Proteinuria

0000093

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
28063	432131

Phenotype Definition

Increased levels of protein in the urine. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	7567	59491	2690.0	0.0	1.937
chr5:33958959	rs28777	SLC45A2	A>C	6426	50566	2254.0	0.0	1.917
chr5:33955326	rs35390	SLC45A2	A>C	4611	36536	1552.0	0.0	1.874
chr5:33955673	rs35391	SLC45A2	C>T	4595	36385	1550.0	0.0	1.876
chr5:33951116	rs35397	SLC45A2	T>G	8610	81498	1513.0	0.0	1.599
chr16:28995057	rs11859822	SPNS1	T>C	3477	25959	1398.0	5.354e-306	1.975
chr16:28954860	rs7203982	-	T>C	3463	25919	1383.0	9.336e-303	1.971
chr23:128718936	rs2362937	OCRL	T>C	2382	17569	1242.0	4.782e-272	2.161
chr16:28974658	rs8044999	NFATC2IP	A>G	2909	21536	1194.0	1.02e-261	1.984
chr15:48426484	rs1426654	SLC24A5	A>G	3185	24341	1189.0	1.487e-260	1.924
chr15:48392165	rs1834640	-	A>G	3505	28119	1119.0	1.966e-245	1.834
chr23:102201216	rs725570	-	A>G	2214	16756	1076.0	5.749e-236	2.101
chr19:42393286	rs717225	ARHGEF1	A>G	2613	19330	1072.0	3.661e-235	1.98
chr6:100241479	rs9495569	-	A>G	2657	20046	1028.0	1.558e-225	1.942
chr2:66725070	rs12995572	MEIS1	G>C	3048	24103	1021.0	5.955e-224	1.857
chr23:71628912	rs3012642	AL133500.1	A>G	2509	20215	1020.0	8.055e-224	1.977
chr15:65114484	rs8031690	PIF1	G>A	1609	10111	1014.0	1.979e-222	2.317
chr2:171380643	rs34020565	MYO3B	T>G	2830	22029	994.0	3.534e-218	1.883
chr19:42392441	rs16975619	ARHGEF1	T>C	2387	17623	983.4	7.155e-216	1.981
chr16:28949473	rs2070961	CD19	C>T	2348	17377	960.0	8.734e-211	1.975
chr10:114758349	rs7903146	TCF7L2	C>T	18644	243508	653.3	4.222e-144	1.268
chr10:114756041	rs4506565	TCF7L2	A>T	20049	267056	571.9	2.126e-126	1.243
chr10:114788815	rs12243326	TCF7L2	T>C	18175	241030	526.7	1.454e-116	1.239
chr10:114808902	rs12255372	TCF7L2	G>T	18385	244434	514.9	5.473e-114	1.235
chr10:114781297	rs10787472	TCF7L2	A>C	27758	400057	211.5	6.554e-48	1.135
chr10:114736614	rs11196175	TCF7L2	T>C	17215	241250	199.9	2.144e-45	1.143
chr10:114740745	rs7081062	TCF7L2	A>G	19817	323653	102.6	4.168e-24	0.9119
chr3:185529080	rs1470579	IGF2BP2	A>C	18734	270931	101.5	6.981e-24	1.098
chr6:20686996	rs9368222	CDKAL1	C>A	15682	224974	101.3	7.874e-24	1.103
chr6:20679709	rs7756992	CDKAL1	A>G	15926	228510	101.0	9.278e-24	1.102
chr3:185530290	rs6769511	IGF2BP2	T>C	18741	270985	100.9	9.744e-24	1.097
chr3:185513392	rs7651090	IGF2BP2	A>G	18690	270207	100.9	9.655e-24	1.097
chr6:20717255	rs9465871	CDKAL1	T>C	10875	153205	98.08	4.024e-23	1.116
chr3:185511687	rs4402960	IGF2BP2	G>T	18662	269987	97.91	4.371e-23	1.096
chr16:53809247	rs1121980	FTO	G>A	24839	364178	97.06	6.738e-23	1.09
chr6:20694884	rs2206734	CDKAL1	C>T	10748	151409	95.96	1.172e-22	1.115
chr16:53800754	rs9940128	FTO	G>A	24845	364348	95.36	1.585e-22	1.09
chr16:53800954	rs1421085	FTO	T>C	23709	346981	94.82	2.083e-22	1.09
chr9:22132076	rs2383208	-	A>G	9127	154266	91.28	1.249e-21	0.8936
chr16:53818460	rs3751812	FTO	G>T	23139	338720	91.17	1.321e-21	1.088

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr10:114758349	rs7903146	TCF7L2	C>T	18644	1194	72.34	1.809e-17	1.347
chr10:114808902	rs12255372	TCF7L2	G>T	18385	1201	58.33	2.221e-14	1.306
chr10:114756041	rs4506565	TCF7L2	A>T	20049	1328	58.32	2.228e-14	1.295
chr10:114788815	rs12243326	TCF7L2	T>C	18175	1196	53.51	2.567e-13	1.291
chr2:44073656	rs41360247	ABCG8	T>C	3554	374	30.84	2.808e-08	0.7305
chr2:44066247	Affx-20090007	ABCG8	G>C	3687	385	30.06	4.196e-08	0.7365
chr10:114781297	rs10787472	TCF7L2	A>C	27758	2006	27.99	1.217e-07	1.181
chr2:44065090	Affx-20089987	ABCG5	G>A	3545	369	27.84	1.315e-07	0.7407
chr10:114736614	rs11196175	TCF7L2	T>C	17215	1199	24.57	7.179e-07	1.19
chr6:45410323	rs34454023	RUNX2	G>A	2337	250	22.58	2.016e-06	0.7233
chr6:32130329	rs34129552	PPT2	C>G	1349	157	22.22	2.427e-06	0.669
chr7:139176178	rs11970854	-	C>T	7616	711	21.67	3.243e-06	0.8198
chr8:88413427	rs3922614	CNBD1	T>C	19483	1689	21.54	3.457e-06	0.8611
chr4:42199292	rs35250584	-	T>C	6338	600	20.52	5.891e-06	0.8125
chr13:86505830	rs9547448	-	A>G	12727	1136	20.52	5.889e-06	0.85
chr1:23090913	rs75642872	EPHB2	C>T	564	76	20.01	7.709e-06	0.5802
chr6:32654714	rs9275184	-	T>C	6312	401	19.96	7.893e-06	1.273
chr6:164323224	rs74704862	-	A>T	906	111	19.86	8.321e-06	0.6377
chr6:8162337	rs77686438	-	A>G	858	106	19.84	8.431e-06	0.6313
chr20:18357556	rs78209042	-	C>T	948	115	19.77	8.732e-06	0.6433

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: E119	Without complications	19/20
ICD: N039	Unspecified	1/20
ICD: O13	Gestational [pregnancy-induced] hypertension without significant proteinuria	1/20
ICD: O269	Pregnancy-related condition, unspecified	1/20
ICD: O809	Single spontaneous delivery, unspecified	2/20

ID	Name	Top Correlation
ICD-10: B961	Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0/20
ICD-10: E101	With ketoacidosis	0/20
ICD-10: J150	Pneumonia due to Klebsiella pneumoniae	0/20
ICD-10: O120	Gestational oedema	0/20
ICD-10: O140	Moderate preeclampsia	0/20
ICD-10: O709	Perineal laceration during delivery, unspecified	0/20
ICD-10: R80	Isolated proteinuria	0/20
ICD-10: R81	Glycosuria	0/20
ICD-10: T464	Angiotensin-converting-enzyme inhibitors	0/20

Proteinuria

0000093

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ