Statistics
| Case | Control |
|---|---|
| 3244 | 456950 |
Phenotype Definition
An abnormality of the mastoid process, which is the conical prominence projecting from the undersurface of the mastoid portion of the temporal bone. [HPO:pnrobinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr9:96366133 | rs62574559 | PHF2 | G>A | 193 | 19140 | 23.66 | 1.149e-06 | 1.426 |
| chr19:41255191 | rs76177309 | C19orf54 | C>T | 227 | 23387 | 22.19 | 2.467e-06 | 1.375 |
| chr7:12856719 | rs17680996 | - | A>G | 926 | 149200 | 21.21 | 4.106e-06 | 0.8496 |
| chr9:96470310 | rs62574024 | - | A>G | 404 | 45607 | 19.94 | 7.996e-06 | 1.258 |
| chr17:69526644 | rs77447012 | - | A>G | 127 | 12058 | 19.68 | 9.134e-06 | 1.487 |
| chr16:10285569 | rs1650397 | - | A>G | 1811 | 277729 | 19.62 | 9.424e-06 | 0.8855 |
| chr8:58660438 | rs34677260 | - | C>T | 168 | 16854 | 19.16 | 1.201e-05 | 1.408 |
| chr22:48912283 | rs133501 | TAFA5 | T>C | 1279 | 160558 | 18.99 | 1.317e-05 | 1.145 |
| chr15:97184582 | rs35752767 | - | G>T | 626 | 74426 | 18.76 | 1.479e-05 | 1.2 |
| chr2:231335094 | rs72983756 | SP100 | C>A | 293 | 32006 | 18.74 | 1.498e-05 | 1.296 |
| chr14:32973881 | rs1956995 | AKAP6 | C>T | 1727 | 264870 | 18.64 | 1.576e-05 | 0.8865 |
| chr15:97201055 | rs4636878 | - | G>A | 816 | 99094 | 18.51 | 1.689e-05 | 1.175 |
| chr17:30635002 | rs11653974 | RHBDL3 | C>T | 2901 | 381576 | 18.49 | 1.706e-05 | 1.111 |
| chr9:3591229 | rs17716128 | - | G>A | 225 | 41698 | 18.41 | 1.782e-05 | 0.7478 |
| chr8:142296482 | rs6989853 | SLC45A4 | C>T | 1082 | 134487 | 18.22 | 1.967e-05 | 1.152 |
| chr14:46064271 | rs11629143 | - | G>A | 1187 | 185976 | 17.95 | 2.27e-05 | 0.8733 |
| chr9:101137859 | rs79202056 | GABBR2 | T>G | 323 | 35990 | 17.83 | 2.413e-05 | 1.273 |
| chr10:71440045 | rs78055882 | - | A>G | 518 | 60820 | 17.61 | 2.706e-05 | 1.212 |
| chr9:135099417 | rs10121025 | NTNG2 | G>C | 3005 | 445657 | 17.6 | 2.73e-05 | 0.9029 |
| chr12:96312686 | rs12368787 | CCDC38 | C>A | 954 | 117701 | 17.59 | 2.736e-05 | 1.158 |
| chr9:96366133 | rs62574559 | PHF2 | G>A | 192 | 18908 | 25.12 | 5.392e-07 | 1.443 |
| chr15:97201055 | rs4636878 | - | G>A | 708 | 84012 | 22.58 | 2.011e-06 | 1.209 |
| chr19:41255191 | rs76177309 | C19orf54 | C>T | 222 | 22870 | 22.34 | 2.282e-06 | 1.381 |
| chr9:96470310 | rs62574024 | - | A>G | 388 | 43340 | 21.82 | 2.993e-06 | 1.278 |
| chr5:123795968 | rs6595529 | - | A>G | 374 | 42255 | 20.3 | 6.61e-06 | 1.273 |
| chr14:32973881 | rs1956995 | AKAP6 | C>T | 1626 | 251882 | 20.23 | 6.868e-06 | 0.8787 |
| chr10:71440045 | rs78055882 | - | A>G | 510 | 59527 | 19.44 | 1.039e-05 | 1.226 |
| chr7:114646114 | rs35318020 | MDFIC | G>A | 816 | 99233 | 19.36 | 1.084e-05 | 1.18 |
| chr4:19996488 | rs17528848 | - | C>T | 240 | 44592 | 19.31 | 1.114e-05 | 0.7492 |
| chr8:58660438 | rs34677260 | - | C>T | 165 | 16557 | 19.25 | 1.145e-05 | 1.413 |
| chr16:10285569 | rs1650397 | - | A>G | 1701 | 262332 | 19.24 | 1.155e-05 | 0.8832 |
| chr22:48912283 | rs133501 | TAFA5 | T>C | 1156 | 144736 | 19.12 | 1.227e-05 | 1.153 |
| chr15:97184582 | rs35752767 | - | G>T | 601 | 71424 | 19.04 | 1.281e-05 | 1.206 |
| chr8:142296482 | rs6989853 | SLC45A4 | C>T | 996 | 123434 | 18.76 | 1.484e-05 | 1.161 |
| chr9:101137859 | rs79202056 | GABBR2 | T>G | 319 | 35435 | 18.75 | 1.49e-05 | 1.283 |
| chr9:3591229 | rs17716128 | - | G>A | 218 | 40828 | 18.69 | 1.535e-05 | 0.7426 |
| chr12:32025486 | rs79026516 | - | G>A | 202 | 21075 | 18.6 | 1.614e-05 | 1.361 |
| chr7:114015707 | rs12705960 | FOXP2 | A>C | 3319 | 443813 | 18.07 | 2.13e-05 | 1.112 |
| chr17:69526644 | rs77447012 | - | A>G | 101 | 9363 | 17.95 | 2.267e-05 | 1.528 |
| chr23:15267248 | Affx-34713990 | ASB9 | A>G | 518 | 88408 | 17.91 | 2.318e-05 | 0.8213 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr23:106016551 | rs2880013 | RNF128 | G>T | 942 | 18935 | 22.9 | 1.71e-06 | 1.193 |
| chr17:69526644 | rs77447012 | - | A>G | 127 | 1947 | 21.32 | 3.878e-06 | 1.528 |
| chr9:3591229 | rs17716128 | - | G>A | 225 | 7076 | 21.14 | 4.266e-06 | 0.7295 |
| chr23:144577772 | rs12687323 | - | T>G | 217 | 3699 | 21.06 | 4.443e-06 | 1.385 |
| chr19:41255191 | rs76177309 | C19orf54 | C>T | 227 | 3893 | 20.63 | 5.558e-06 | 1.369 |
| chr9:96366133 | rs62574559 | PHF2 | G>A | 193 | 3224 | 20.54 | 5.846e-06 | 1.403 |
| chr8:58660438 | rs34677260 | - | C>T | 168 | 2750 | 20.04 | 7.575e-06 | 1.431 |
| chr10:71440045 | rs78055882 | - | A>G | 518 | 9931 | 19.91 | 8.127e-06 | 1.232 |
| chr2:231335094 | rs72983756 | SP100 | C>A | 293 | 5267 | 19.06 | 1.269e-05 | 1.306 |
| chr8:142296482 | rs6989853 | SLC45A4 | C>T | 1082 | 22187 | 19.06 | 1.265e-05 | 1.159 |
| chr7:12856719 | rs17680996 | - | A>G | 926 | 24606 | 19.02 | 1.296e-05 | 0.8549 |
| chr15:97184582 | rs35752767 | - | G>T | 626 | 12295 | 18.8 | 1.448e-05 | 1.204 |
| chr9:96470310 | rs62574024 | - | A>G | 404 | 7576 | 18.75 | 1.487e-05 | 1.255 |
| chr9:34392908 | rs10758259 | C9orf24 | A>G | 1332 | 27741 | 18.68 | 1.544e-05 | 1.144 |
| chr14:32973881 | rs1956995 | AKAP6 | C>T | 1727 | 43967 | 18.63 | 1.591e-05 | 0.8848 |
| chr14:58372711 | rs12435743 | SLC35F4 | T>C | 847 | 17123 | 18.48 | 1.719e-05 | 1.176 |
| chr11:61547237 | rs108499 | MYRF | C>T | 2421 | 52442 | 18.26 | 1.925e-05 | 1.116 |
| chr23:105911987 | rs6622104 | RADX | A>G | 994 | 20444 | 18.09 | 2.104e-05 | 1.166 |
| chr16:10285569 | rs1650397 | - | A>G | 1811 | 45948 | 17.93 | 2.29e-05 | 0.8885 |
| chr8:55442544 | rs77645749 | RP1 | G>T | 197 | 3376 | 17.9 | 2.332e-05 | 1.368 |
| chr15:97201055 | rs4636878 | - | G>A | 708 | 13875 | 22.71 | 1.885e-06 | 1.214 |
| chr10:71440045 | rs78055882 | - | A>G | 510 | 9695 | 22.35 | 2.27e-06 | 1.25 |
| chr9:96366133 | rs62574559 | PHF2 | G>A | 192 | 3174 | 22.32 | 2.311e-06 | 1.425 |
| chr23:106016551 | rs2880013 | RNF128 | G>T | 874 | 17584 | 22.17 | 2.5e-06 | 1.197 |
| chr9:3591229 | rs17716128 | - | G>A | 218 | 6933 | 21.47 | 3.588e-06 | 0.724 |
| chr16:12743796 | rs7193999 | - | G>A | 165 | 2671 | 21.47 | 3.592e-06 | 1.454 |
| chr19:41255191 | rs76177309 | C19orf54 | C>T | 222 | 3791 | 21.36 | 3.8e-06 | 1.382 |
| chr8:58660438 | rs34677260 | - | C>T | 165 | 2687 | 20.75 | 5.242e-06 | 1.445 |
| chr14:32973881 | rs1956995 | AKAP6 | C>T | 1626 | 41810 | 20.13 | 7.221e-06 | 0.8771 |
| chr15:97184582 | rs35752767 | - | G>T | 601 | 11788 | 19.3 | 1.117e-05 | 1.212 |
| chr9:96470310 | rs62574024 | - | A>G | 388 | 7260 | 19.1 | 1.24e-05 | 1.264 |
| chr11:61547237 | rs108499 | MYRF | C>T | 2343 | 50839 | 18.85 | 1.416e-05 | 1.122 |
| chr8:55442544 | rs77645749 | RP1 | G>T | 194 | 3315 | 18.48 | 1.714e-05 | 1.379 |
| chr17:69526644 | rs77447012 | - | A>G | 101 | 1537 | 17.87 | 2.368e-05 | 1.544 |
| chr8:142296482 | rs6989853 | SLC45A4 | C>T | 996 | 20495 | 17.75 | 2.522e-05 | 1.16 |
| chr2:231335094 | rs72983756 | SP100 | C>A | 276 | 4997 | 17.55 | 2.794e-05 | 1.302 |
| chr3:145943792 | rs9838816 | PLSCR4 | A>C | 2349 | 51081 | 17.38 | 3.068e-05 | 1.116 |
| chr14:71101054 | rs73286073 | - | G>A | 601 | 11932 | 17.38 | 3.059e-05 | 1.201 |
| chr2:33678924 | Affx-19935560 | RASGRP3 | A>G | 3086 | 68087 | 17.31 | 3.168e-05 | 1.112 |
| chr2:160604936 | rs13024801 | MARCHF7 | G>A | 529 | 10334 | 17.29 | 3.212e-05 | 1.213 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: H830 | Labyrinthitis | 1/20 |