Abnormality of the outer ear

0000356

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
26352	433842

Phenotype Definition

An abnormality of the external ear. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr8:145639681	rs1871534	SLC39A4	G>C	705	17440	113.4	1.797e-26	0.6644
chr15:48426484	rs1426654	SLC24A5	A>G	1167	26359	112.5	2.824e-26	0.7266
chr1:159174683	rs2814778	ACKR1	T>C	772	18605	108.2	2.477e-25	0.6822
chr17:58508582	rs8071181	C17orf64	G>A	609	14808	88.91	4.136e-21	0.6773
chr15:48392165	rs1834640	-	A>G	1422	30202	87.91	6.862e-21	0.7733
chr2:163216109	rs3213843	GCA	C>T	455	11697	87.55	8.216e-21	0.6406
chr6:161010118	rs10455872	LPA	A>G	4756	68943	84.05	4.827e-20	1.154
chr6:136480972	rs9483910	PDE7B	C>T	911	20459	83.89	5.244e-20	0.7323
chr6:136505700	rs6570070	PDE7B	G>C	393	10244	80.41	3.045e-19	0.6322
chr4:110940045	rs4698804	-	T>C	763	17501	80.22	3.344e-19	0.7174
chr1:25589335	rs28670433	RSRP1	A>G	585	14048	80.16	3.447e-19	0.6855
chr2:226686177	rs7581591	-	T>C	842	18993	79.3	5.337e-19	0.73
chr9:22096055	rs10757274	-	A>G	27943	444609	78.93	6.435e-19	1.081
chr1:210419650	rs12088691	SERTAD4	A>C	462	11583	78.77	6.98e-19	0.6572
chr3:188327555	rs7645635	LPP	T>C	575	13801	78.54	7.854e-19	0.6859
chr9:22098574	rs4977574	-	A>G	27822	442599	78.33	8.723e-19	1.08
chr1:25555672	rs10903036	SYF2	C>T	539	13074	77.81	1.136e-18	0.6789
chr13:113979968	rs200506581	GRTP1	C>CCACA	498	12228	76.62	2.067e-18	0.6707
chr6:160997118	rs74617384	LPA	A>T	4612	67215	76.57	2.127e-18	1.149
chr24:14850341	rs2032598	USP9Y	T>C	89	2723	76.49	2.217e-18	0.4014
chr6:161010118	rs10455872	LPA	A>G	4693	68057	76.58	2.11e-18	1.148
chr6:160997118	rs74617384	LPA	A>T	4549	66339	69.42	7.938e-17	1.143
chr9:22096055	rs10757274	-	A>G	26630	423523	60.0	9.506e-15	1.072
chr9:22098574	rs4977574	-	A>G	26540	422186	58.05	2.551e-14	1.071
chr9:22125503	rs1333049	-	G>C	26268	417650	57.05	4.252e-14	1.07
chr9:22124477	rs10757278	-	A>G	26281	417825	56.88	4.641e-14	1.07
chr9:22081850	rs6475606	-	C>T	26292	418470	55.17	1.103e-13	1.069
chr9:22088260	rs10757272	-	C>T	26439	420767	55.05	1.172e-13	1.069
chr9:22125347	rs1333048	-	A>C	27115	432026	54.94	1.244e-13	1.069
chr9:22115959	rs2383207	-	G>A	24751	421270	49.84	1.667e-12	0.9385
chr11:111165009	rs7103178	-	T>C	16680	262113	48.53	3.26e-12	1.07
chr11:111171709	rs3802842	COLCA2	A>C	16639	261504	48.43	3.42e-12	1.07
chr9:22083404	rs1333040	-	T>C	21057	359501	45.73	1.36e-11	0.9399
chr11:111125512	rs2001754	C11orf53	A>G	18490	292690	41.23	1.356e-10	1.062
chr6:160848743	rs9457925	SLC22A3	G>A	1167	15878	40.29	2.19e-10	1.215
chr6:160922870	rs117733303	-	A>G	1162	15822	39.88	2.696e-10	1.214
chr6:160961137	rs3798220	LPA	T>C	1143	15639	37.16	1.087e-09	1.207
chr6:160687412	rs10080815	SLC22A2	T>G	1213	16924	31.83	1.685e-08	1.185
chr6:396321	rs12203592	IRF4	C>T	11918	186997	30.97	2.622e-08	1.062
chr9:22068652	rs4977756	-	A>G	20499	348141	30.46	3.405e-08	0.9505

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr9:22081850	rs6475606	-	C>T	26292	27068	35.35	2.751e-09	1.075
chr6:161010118	rs10455872	LPA	A>G	4693	4451	34.83	3.6e-09	1.138
chr9:22083404	rs1333040	-	T>C	21057	23478	34.76	3.728e-09	0.9298
chr9:22096055	rs10757274	-	A>G	26630	27462	33.87	5.889e-09	1.073
chr9:22124477	rs10757278	-	A>G	26281	27077	33.01	9.155e-09	1.072
chr9:22125347	rs1333048	-	A>C	27115	27984	32.74	1.056e-08	1.072
chr9:22125503	rs1333049	-	G>C	26268	27075	32.68	1.089e-08	1.072
chr9:22098574	rs4977574	-	A>G	26540	27387	32.36	1.283e-08	1.072
chr9:22115959	rs2383207	-	G>A	24751	27396	31.43	2.073e-08	0.9342
chr9:22088260	rs10757272	-	C>T	26439	27284	30.77	2.9e-08	1.07
chr6:160997118	rs74617384	LPA	A>T	4549	4357	29.57	5.395e-08	1.128
chr11:111171709	rs3802842	COLCA2	A>C	16639	16980	25.04	5.602e-07	1.068
chr11:111165009	rs7103178	-	T>C	16680	17029	24.46	7.6e-07	1.067
chr6:12903957	rs9349379	PHACTR1	A>G	21874	22552	22.72	1.871e-06	1.061
chr6:50290862	rs4524605	-	G>A	22046	24270	22.55	2.046e-06	0.9426
chr15:38917854	rs117253093	-	G>A	1263	1117	21.54	3.459e-06	1.212
chr8:117630683	rs16892766	-	A>C	4391	4262	21.48	3.579e-06	1.109
chr6:50263685	rs1492623	-	C>T	20633	22802	21.37	3.779e-06	0.9438
chr9:84824303	rs117921372	-	C>T	1871	1718	21.07	4.435e-06	1.169
chr9:22003223	rs3217992	AL359922.1	C>T	19739	20337	21.04	4.506e-06	1.059

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: D125	Sigmoid colon	5/20
ICD: H538	Other visual disturbances	2/20
ICD: I258	Other forms of chronic ischaemic heart disease	6/20
ICD: I73	Other peripheral vascular diseases	4/20

ID	Name	Top Correlation
ICD-10: C187	Sigmoid colon	0/20
ICD-10: D695	Secondary thrombocytopenia	0/20
ICD-10: H539	Visual disturbance, unspecified	0/20
ICD-10: H571	Ocular pain	0/20
ICD-10: H609	Otitis externa, unspecified	0/20
ICD-10: H611	Non-infective disorders of pinna	0/20
ICD-10: H612	Impacted cerumen	0/20
ICD-10: H729	Perforation of tympanic membrane, unspecified	0/20
ICD-10: H740	Tympanosclerosis	0/20
ICD-10: J398	Other specified diseases of upper respiratory tract	0/20
ICD-10: O351	Maternal care for (suspected) chromosomal abnormality in foetus	0/20
ICD-10: Q600	Renal agenesis, unilateral	0/20
ICD-10: Y838	Other surgical procedures	0/20
ICD-10: Y839	Surgical procedure, unspecified	0/20

Abnormality of the outer ear

0000356

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ