Statistics
| Case | Control |
|---|---|
| 22433 | 437761 |
Phenotype Definition
An abnormality of the lobule of pinna. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr15:48426484 | rs1426654 | SLC24A5 | A>G | 959 | 26567 | 114.0 | 1.317e-26 | 0.7027 |
| chr6:161010118 | rs10455872 | LPA | A>G | 4159 | 69540 | 109.9 | 1.007e-25 | 1.191 |
| chr8:145639681 | rs1871534 | SLC39A4 | G>C | 579 | 17566 | 109.8 | 1.083e-25 | 0.6429 |
| chr9:22096055 | rs10757274 | - | A>G | 23987 | 448565 | 107.6 | 3.272e-25 | 1.103 |
| chr9:22098574 | rs4977574 | - | A>G | 23870 | 446551 | 105.4 | 9.893e-25 | 1.102 |
| chr6:160997118 | rs74617384 | LPA | A>T | 4037 | 67790 | 102.8 | 3.73e-24 | 1.187 |
| chr1:159174683 | rs2814778 | ACKR1 | T>C | 639 | 18738 | 102.6 | 4.171e-24 | 0.6654 |
| chr9:22124477 | rs10757278 | - | A>G | 23643 | 442457 | 98.76 | 2.857e-23 | 1.098 |
| chr9:22088260 | rs10757272 | - | C>T | 23896 | 447852 | 95.87 | 1.225e-22 | 1.097 |
| chr9:22125503 | rs1333049 | - | G>C | 23635 | 442803 | 94.44 | 2.527e-22 | 1.096 |
| chr9:22125347 | rs1333048 | - | A>C | 24457 | 459200 | 93.31 | 4.468e-22 | 1.095 |
| chr17:58508582 | rs8071181 | C17orf64 | G>A | 501 | 14916 | 86.25 | 1.589e-20 | 0.6564 |
| chr15:48392165 | rs1834640 | - | A>G | 1188 | 30436 | 83.9 | 5.216e-20 | 0.7607 |
| chr2:163216109 | rs3213843 | GCA | C>T | 375 | 11777 | 82.64 | 9.826e-20 | 0.6223 |
| chr6:136480972 | rs9483910 | PDE7B | C>T | 759 | 20611 | 79.25 | 5.478e-19 | 0.7187 |
| chr2:226686177 | rs7581591 | - | T>C | 694 | 19141 | 79.11 | 5.882e-19 | 0.7085 |
| chr12:56722060 | rs1918496 | PAN2 | G>T | 361 | 11256 | 77.1 | 1.628e-18 | 0.6268 |
| chr1:25589335 | rs28670433 | RSRP1 | A>G | 485 | 14148 | 75.62 | 3.441e-18 | 0.6696 |
| chr16:7465748 | rs4786166 | RBFOX1 | C>T | 617 | 17177 | 74.54 | 5.95e-18 | 0.7017 |
| chr24:14850341 | rs2032598 | USP9Y | T>C | 73 | 2739 | 74.51 | 6.025e-18 | 0.373 |
| chr6:161010118 | rs10455872 | LPA | A>G | 4102 | 68648 | 99.14 | 2.355e-23 | 1.183 |
| chr6:160997118 | rs74617384 | LPA | A>T | 3980 | 66908 | 92.17 | 7.962e-22 | 1.178 |
| chr9:22096055 | rs10757274 | - | A>G | 22887 | 427266 | 85.2 | 2.693e-20 | 1.094 |
| chr9:22098574 | rs4977574 | - | A>G | 22798 | 425928 | 81.9 | 1.431e-19 | 1.092 |
| chr9:22124477 | rs10757278 | - | A>G | 22565 | 421541 | 77.64 | 1.238e-18 | 1.089 |
| chr9:22088260 | rs10757272 | - | C>T | 22713 | 424493 | 77.61 | 1.257e-18 | 1.089 |
| chr9:22125503 | rs1333049 | - | G>C | 22553 | 421365 | 77.38 | 1.41e-18 | 1.089 |
| chr9:22125347 | rs1333048 | - | A>C | 23287 | 435854 | 77.25 | 1.507e-18 | 1.089 |
| chr9:22081850 | rs6475606 | - | C>T | 22562 | 422200 | 73.33 | 1.096e-17 | 1.086 |
| chr9:22115959 | rs2383207 | - | G>A | 20868 | 425153 | 71.63 | 2.597e-17 | 0.9211 |
| chr9:22083404 | rs1333040 | - | T>C | 17733 | 362825 | 65.99 | 4.531e-16 | 0.9227 |
| chr6:160848743 | rs9457925 | SLC22A3 | G>A | 1024 | 16021 | 48.0 | 4.263e-12 | 1.253 |
| chr6:160922870 | rs117733303 | - | A>G | 1019 | 15965 | 47.27 | 6.188e-12 | 1.251 |
| chr11:111165009 | rs7103178 | - | T>C | 14239 | 264554 | 46.62 | 8.631e-12 | 1.074 |
| chr11:111171709 | rs3802842 | COLCA2 | A>C | 14204 | 263939 | 46.32 | 1.004e-11 | 1.073 |
| chr6:160961137 | rs3798220 | LPA | T>C | 1001 | 15781 | 43.68 | 3.871e-11 | 1.243 |
| chr11:111125512 | rs2001754 | C11orf53 | A>G | 15800 | 295380 | 42.15 | 8.433e-11 | 1.068 |
| chr6:160687412 | rs10080815 | SLC22A2 | T>G | 1061 | 17076 | 38.13 | 6.624e-10 | 1.218 |
| chr9:22068652 | rs4977756 | - | A>G | 17362 | 351278 | 35.31 | 2.817e-09 | 0.9426 |
| chr9:22003223 | rs3217992 | AL359922.1 | C>T | 16978 | 319272 | 35.14 | 3.072e-09 | 1.061 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr13:103051907 | rs80181797 | FGF14 | G>A | 1011 | 139 | 30.3 | 3.708e-08 | 0.6055 |
| chr8:13828275 | rs1351985 | - | G>T | 10163 | 1003 | 28.14 | 1.13e-07 | 0.8154 |
| chr3:131377547 | rs11713883 | CPNE4 | A>T | 9614 | 948 | 26.82 | 2.23e-07 | 0.8162 |
| chr9:22083404 | rs1333040 | - | T>C | 17733 | 1651 | 24.59 | 7.082e-07 | 0.8442 |
| chr4:77878521 | rs12650893 | SEPTIN11 | G>A | 14774 | 1105 | 23.03 | 1.595e-06 | 1.195 |
| chr12:125239116 | rs73227548 | - | C>T | 686 | 96 | 22.08 | 2.611e-06 | 0.5988 |
| chr13:103018693 | rs76244678 | FGF14 | G>A | 1136 | 144 | 21.88 | 2.896e-06 | 0.6579 |
| chr13:103002381 | rs9585895 | FGF14 | T>C | 1951 | 227 | 21.84 | 2.962e-06 | 0.7145 |
| chr1:234046376 | rs115240947 | SLC35F3 | T>C | 2658 | 295 | 21.7 | 3.181e-06 | 0.7434 |
| chr1:30318660 | rs77945679 | - | C>T | 738 | 100 | 20.39 | 6.302e-06 | 0.617 |
| chr2:65398107 | rs79182367 | - | T>C | 1568 | 186 | 19.94 | 7.988e-06 | 0.7025 |
| chr7:43458506 | rs6949148 | HECW1 | T>C | 18085 | 1671 | 19.91 | 8.131e-06 | 0.8589 |
| chr13:62383603 | rs73213595 | - | A>G | 2709 | 298 | 19.84 | 8.439e-06 | 0.7541 |
| chr22:24577986 | rs3788368 | SUSD2 | T>C | 3285 | 353 | 19.83 | 8.479e-06 | 0.7703 |
| chr8:84988322 | rs34067813 | - | A>G | 10195 | 978 | 19.59 | 9.574e-06 | 0.8422 |
| chr9:22096055 | rs10757274 | - | A>G | 22887 | 1793 | 19.34 | 1.096e-05 | 1.161 |
| chr22:19952132 | rs4646316 | COMT | C>T | 10822 | 1038 | 19.25 | 1.146e-05 | 0.8461 |
| chr20:21416589 | rs118076847 | - | C>A | 800 | 105 | 19.24 | 1.152e-05 | 0.6326 |
| chr4:2277234 | rs79034187 | ZFYVE28 | T>C | 756 | 100 | 18.67 | 1.557e-05 | 0.6302 |
| chr14:84470423 | rs17654303 | - | G>A | 1270 | 154 | 18.62 | 1.594e-05 | 0.6883 |