Case | Control |
---|---|
67838 | 392356 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr1:236085940 | rs12038310 | - | C>T | 1851 | 13425 | 81.36 | 1.885e-19 | 0.7988 |
chr15:48426484 | rs1426654 | SLC24A5 | A>G | 3522 | 24004 | 80.14 | 3.492e-19 | 0.8492 |
chr20:19214390 | rs6136658 | SLC24A3 | G>A | 1649 | 12026 | 75.88 | 3.014e-18 | 0.7948 |
chr6:93667780 | rs9363020 | - | G>A | 1453 | 10538 | 63.49 | 1.614e-15 | 0.7996 |
chr17:14424508 | rs80090021 | - | C>A | 1313 | 9625 | 62.97 | 2.104e-15 | 0.7913 |
chr6:170242949 | rs9396958 | - | T>C | 2013 | 14101 | 62.5 | 2.668e-15 | 0.8274 |
chr5:33951693 | rs16891982 | SLC45A2 | G>C | 9149 | 57909 | 61.45 | 4.541e-15 | 0.9129 |
chr2:211717706 | rs12995612 | - | C>G | 2068 | 14404 | 60.21 | 8.525e-15 | 0.8323 |
chr5:33958959 | rs28777 | SLC45A2 | A>C | 7730 | 49262 | 60.06 | 9.218e-15 | 0.9071 |
chr11:44843134 | rs11038167 | TSPAN18 | A>C | 1255 | 9194 | 59.98 | 9.59e-15 | 0.7917 |
chr2:26113913 | rs78404020 | - | A>G | 1709 | 12108 | 59.61 | 1.155e-14 | 0.8184 |
chr2:3313043 | rs73133173 | EIPR1 | A>C | 1798 | 12665 | 59.06 | 1.532e-14 | 0.8231 |
chr6:170602429 | rs17860704 | DLL1 | T>C | 1435 | 10283 | 55.93 | 7.512e-14 | 0.8094 |
chr6:22050187 | rs1736507 | - | C>A | 1816 | 12697 | 55.87 | 7.759e-14 | 0.8282 |
chr15:48392165 | rs1834640 | - | A>G | 4180 | 27444 | 55.56 | 9.087e-14 | 0.882 |
chr20:2315543 | rs6132532 | AL121899.2 | A>G | 6705 | 42829 | 54.28 | 1.738e-13 | 0.9056 |
chr5:33951116 | rs35397 | SLC45A2 | T>G | 12489 | 77619 | 53.65 | 2.396e-13 | 0.9287 |
chr10:108672251 | rs1572457 | SORCS1 | C>T | 1441 | 10277 | 53.63 | 2.426e-13 | 0.8133 |
chr1:206665837 | rs11118256 | IKBKE | G>A | 1260 | 9100 | 52.74 | 3.801e-13 | 0.8034 |
chr1:29783282 | rs6676357 | - | T>C | 1222 | 8832 | 51.67 | 6.576e-13 | 0.8026 |
chr25:2644302 | rs1136470 | - | C>T | 17850 | 107964 | 33.74 | 6.305e-09 | 0.9508 |
chr6:396321 | rs12203592 | IRF4 | C>T | 30112 | 168803 | 30.81 | 2.848e-08 | 1.04 |
chr15:74716174 | rs11856835 | SEMA7A | G>A | 68229 | 388531 | 28.08 | 1.164e-07 | 1.032 |
chr17:2092064 | rs11078856 | SMG6 | G>A | 43062 | 243520 | 27.27 | 1.767e-07 | 1.034 |
chr6:14719496 | rs17119 | - | A>G | 25625 | 153037 | 26.97 | 2.063e-07 | 0.9617 |
chr5:4096237 | rs1187477 | - | C>T | 29199 | 164049 | 26.19 | 3.096e-07 | 1.037 |
chr6:14724910 | rs13197778 | - | T>C | 24671 | 147474 | 26.11 | 3.221e-07 | 0.9618 |
chr17:2091765 | rs903160 | SMG6 | C>T | 43454 | 246036 | 24.91 | 6.013e-07 | 1.032 |
chr6:14716037 | rs1267495 | - | T>C | 25526 | 152137 | 24.54 | 7.294e-07 | 0.9635 |
chr6:421281 | rs62389423 | - | G>A | 24497 | 137368 | 24.28 | 8.312e-07 | 1.038 |
chr2:192668645 | rs4853639 | - | T>C | 13917 | 77104 | 24.19 | 8.717e-07 | 1.049 |
chr2:204836598 | rs1075547 | - | C>T | 53530 | 304165 | 24.07 | 9.289e-07 | 1.03 |
chr6:14733033 | rs62389638 | - | T>C | 24646 | 146991 | 24.02 | 9.559e-07 | 0.9634 |
chr22:45703075 | rs226499 | - | G>A | 50230 | 295913 | 23.81 | 1.062e-06 | 0.9707 |
chr12:123921264 | rs28434767 | - | G>T | 37536 | 222077 | 23.49 | 1.256e-06 | 0.9687 |
chr20:21253368 | rs78910017 | - | G>A | 2984 | 18966 | 23.46 | 1.273e-06 | 0.9081 |
chr22:45718743 | rs7290139 | FAM118A | G>A | 50978 | 300344 | 23.34 | 1.355e-06 | 0.9711 |
chr10:22729783 | rs7921007 | SPAG6 | C>A | 4861 | 30243 | 23.23 | 1.439e-06 | 0.927 |
chr5:127548955 | rs36694 | - | A>C | 35655 | 201353 | 23.08 | 1.552e-06 | 1.033 |
chr17:2017079 | rs2760743 | SMG6 | C>A | 40531 | 229334 | 23.06 | 1.573e-06 | 1.031 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr15:48426484 | rs1426654 | SLC24A5 | A>G | 3522 | 6199 | 186.3 | 2.073e-42 | 0.7475 |
chr15:48392165 | rs1834640 | - | A>G | 4180 | 6984 | 144.4 | 2.859e-33 | 0.7879 |
chr25:2692710 | rs2259750 | - | A>G | 27377 | 33268 | 143.2 | 5.297e-33 | 1.115 |
chr1:159174683 | rs2814778 | ACKR1 | T>C | 2649 | 4626 | 130.9 | 2.585e-30 | 0.7552 |
chr13:72441665 | rs3759505 | - | C>T | 2178 | 3880 | 124.4 | 6.892e-29 | 0.7407 |
chr2:226686177 | rs7581591 | - | T>C | 2644 | 4587 | 123.6 | 1.014e-28 | 0.7607 |
chr5:147666044 | rs7707813 | - | T>C | 2495 | 4357 | 123.3 | 1.18e-28 | 0.7553 |
chr25:2644302 | rs1136470 | - | C>T | 18776 | 27489 | 122.4 | 1.861e-28 | 0.8933 |
chr5:147671850 | rs7724380 | - | G>A | 2691 | 4638 | 119.7 | 7.302e-28 | 0.7655 |
chr25:2661556 | rs73188900 | - | A>C | 2925 | 2935 | 117.7 | 2.016e-27 | 1.33 |
chr13:72463541 | rs1460465 | - | A>G | 2070 | 3680 | 116.4 | 3.871e-27 | 0.7424 |
chr3:122328753 | rs2173764 | PARP15 | A>G | 1870 | 3367 | 114.8 | 8.506e-27 | 0.7333 |
chr2:237222746 | rs60984264 | - | G>A | 2515 | 4343 | 113.6 | 1.572e-26 | 0.7642 |
chr9:127267689 | rs3814134 | NR5A1 | A>G | 3978 | 6497 | 110.7 | 6.721e-26 | 0.8067 |
chr19:42393286 | rs717225 | ARHGEF1 | A>G | 2965 | 5002 | 110.6 | 7.318e-26 | 0.7819 |
chr8:145639681 | rs1871534 | SLC39A4 | G>C | 2501 | 4306 | 110.2 | 8.795e-26 | 0.7666 |
chr17:58508582 | rs8071181 | C17orf64 | G>A | 2097 | 3687 | 108.5 | 2.08e-25 | 0.751 |
chr19:42392441 | rs16975619 | ARHGEF1 | T>C | 2683 | 4567 | 107.8 | 2.913e-25 | 0.7752 |
chr23:128718936 | rs2362937 | OCRL | T>C | 2532 | 5114 | 106.4 | 6.101e-25 | 0.7762 |
chr25:155058865 | rs73234550 | - | G>A | 4757 | 5143 | 106.2 | 6.614e-25 | 1.234 |
chr25:2644302 | rs1136470 | - | C>T | 17850 | 26013 | 127.1 | 1.79e-29 | 0.8887 |
chr25:2692710 | rs2259750 | - | A>G | 25433 | 30874 | 110.0 | 9.686e-26 | 1.104 |
chr25:2661556 | rs73188900 | - | A>C | 2894 | 2911 | 107.4 | 3.683e-25 | 1.315 |
chr25:155058865 | rs73234550 | - | G>A | 4706 | 5089 | 95.64 | 1.38e-22 | 1.222 |
chr25:2679949 | rs311121 | - | G>T | 18897 | 26892 | 82.17 | 1.247e-19 | 0.9112 |
chr25:2645366 | rs311083 | - | C>G | 50149 | 63295 | 78.3 | 8.845e-19 | 1.069 |
chr25:154998312 | rs306885 | - | T>G | 63726 | 86601 | 73.63 | 9.422e-18 | 0.9398 |
chr25:154935282 | rs112437556 | - | C>T | 4075 | 6267 | 62.9 | 2.173e-15 | 0.8503 |
chr25:155104608 | rs5940618 | - | G>A | 27856 | 34681 | 60.05 | 9.255e-15 | 1.072 |
chr25:2676915 | rs311115 | - | G>C | 9679 | 14015 | 57.99 | 2.628e-14 | 0.9007 |
chr25:2685254 | rs311142 | - | C>T | 53316 | 67833 | 54.07 | 1.932e-13 | 1.056 |
chr25:2681878 | rs73190930 | - | A>G | 16810 | 23685 | 53.71 | 2.325e-13 | 0.9239 |
chr25:154986418 | rs142918084 | - | C>G | 4385 | 6641 | 53.43 | 2.68e-13 | 0.8651 |
chr23:154395148 | rs113038688 | - | C>T | 2707 | 3546 | 50.6 | 1.134e-12 | 1.202 |
chr25:2677358 | rs66607823 | - | A>G | 13566 | 19216 | 49.0 | 2.564e-12 | 0.9205 |
chr25:2669401 | rs146821057 | - | A>G | 16982 | 23848 | 48.65 | 3.065e-12 | 0.9277 |
chr25:2676160 | rs312232 | - | C>T | 29079 | 40071 | 48.15 | 3.956e-12 | 0.9413 |
chr25:155013081 | rs146997510 | - | T>A | 3913 | 4430 | 48.05 | 4.16e-12 | 1.167 |
chr25:155085824 | rs1969622 | - | G>C | 19018 | 23471 | 47.75 | 4.841e-12 | 1.075 |
chr25:155053713 | rs28884873 | - | G>A | 21067 | 26151 | 45.28 | 1.707e-11 | 1.07 |
ID | Name | Top Correlation |
---|---|---|
ICD: C445 | Skin of trunk | 5/20 |
ICD: K621 | Rectal polyp | 5/20 |
ICD: L720 | Epidermal cyst | 1/20 |
ICD: L900 | Lichen sclerosus et atrophicus | 1/20 |