Abnormality of the hypothalamus-pituitary axis


Normal Case/Contol

GWAS of 0000864

Sibling Case/Control

No sibling GWAS available 0000864


Case Control
41876 418318

Phenotype Definition

Abnormality of the pituitary gland (also known as hypophysis), which is an endocrine gland that protrudes from the bottom of the hypothalamus at the base of the brain. The pituitary gland secretes the hormones ACTH, TSH, PRL, GH, endorphins, FSH, LH, oxytocin, and antidiuretic hormone. The secretion of hormones from the anterior pituitary is under the strict control of hypothalamic hormones, and the posterior pituitary is essentially an extension of the hypothalamus, so that hypothalamus and pituitary gland may be regarded as a functional unit. [DDD:spark]

Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: C442 Skin of ear and external auricular canal 8/20
ICD: C443 Skin of other and unspecified parts of face 8/20
ICD: C444 Skin of scalp and neck 7/20
ICD: C446 Skin of upper limb, including shoulder 5/20
ICD: D352 Pituitary gland 2/20
ICD: E039 Hypothyroidism, unspecified 7/20
ICD: H538 Other visual disturbances 2/20
ICD: N701 Chronic salpingitis and oophoritis 4/20