Abnormality of the larynx

0001600

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
10138	450056

Phenotype Definition

An abnormality of the larynx. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr1:159174683	rs2814778	ACKR1	T>C	559	18818	40.17	2.324e-10	1.316
chr3:45987980	rs2234355	FYCO1	G>A	323	10000	39.63	3.063e-10	1.429
chr3:46036264	rs55844314	FYCO1	T>G	839	29823	38.64	5.092e-10	1.248
chr15:45694768	rs1834686	SPATA5L1	G>T	317	9902	36.91	1.239e-09	1.415
chr1:173579034	rs12065033	AL139142.2	C>T	449	14892	35.78	2.207e-09	1.334
chr9:117110112	Affx-52344420	AKNA	T>TG	427	14152	34.13	5.153e-09	1.335
chr23:19215613	rs5955734	-	C>G	805	29220	33.99	5.532e-09	1.238
chr23:64367019	rs7064929	-	G>A	498	17068	33.95	5.66e-09	1.308
chr12:56755058	rs4301822	APOF	A>G	374	12238	32.22	1.378e-08	1.349
chr15:45695612	rs1346265	SPATA5L1	C>T	348	11322	31.52	1.971e-08	1.359
chr13:75861001	rs557337	TBC1D4	A>G	1619	62210	31.42	2.083e-08	1.158
chr1:207782889	rs17047661	CR1	A>G	415	13904	30.78	2.893e-08	1.321
chr10:65924376	rs4390238	-	G>T	352	11523	30.66	3.07e-08	1.351
chr15:45491394	rs1648299	SHF	T>C	487	16672	30.61	3.159e-08	1.292
chr23:109671384	rs768312	AMMECR1	T>C	444	15195	30.48	3.369e-08	1.308
chr1:4031644	rs58856511	-	C>G	986	36466	30.29	3.714e-08	1.199
chr20:57885858	rs197185	EDN3	A>G	781	28326	29.48	5.66e-08	1.222
chr1:49177000	rs405325	AGBL4	G>A	350	11527	29.23	6.437e-08	1.343
chr5:64447660	rs6879867	ADAMTS6	G>A	354	11683	29.05	7.048e-08	1.339
chr12:80106323	rs2463171	-	G>A	835	30568	28.64	8.694e-08	1.211
chr9:32436683	rs10813815	ACO1	G>C	6061	283061	21.22	4.085e-06	0.931
chr10:14720733	rs6602750	FAM107B	G>A	7982	339877	21.1	4.351e-06	1.069
chr12:100562476	rs114732197	-	C>T	400	14142	20.56	5.79e-06	1.261
chr6:31862876	rs115062572	EHMT2	C>T	634	23527	20.49	6.002e-06	1.203
chr6:31631531	rs114733011	GPANK1	G>A	634	23542	20.29	6.652e-06	1.202
chr4:160787840	rs114585534	-	A>G	1139	44337	20.09	7.377e-06	1.148
chr16:65193896	rs77835220	-	T>C	360	12622	19.92	8.062e-06	1.271
chr1:236147660	rs34415891	NID1	C>T	609	32329	19.9	8.169e-06	0.8311
chr7:42916582	rs114911199	-	C>T	404	14351	19.87	8.285e-06	1.254
chr23:130451880	rs140935000	IGSF1	C>T	550	20475	19.61	9.488e-06	1.215
chr9:32433526	rs10970976	ACO1	T>C	6131	285406	19.3	1.115e-05	0.9343
chr2:67992075	rs730424	-	G>A	1594	63554	19.29	1.121e-05	1.123
chr10:118996115	rs4081624	-	A>C	4851	227459	19.28	1.129e-05	0.9293
chr12:19344476	rs117787503	PLEKHA5	A>G	468	16966	19.26	1.143e-05	1.231
chr2:120383138	rs77292092	CFAP221	CATT>C	3386	160602	18.88	1.39e-05	0.92
chr12:19371221	rs79834800	PLEKHA5	A>G	443	15999	18.81	1.447e-05	1.235
chr1:24999518	rs114067890	SRRM1	A>G	168	10405	18.73	1.507e-05	0.7143
chr12:19226740	rs116942698	-	G>A	970	37535	18.73	1.503e-05	1.155
chr20:43235738	rs78824799	PKIG	A>G	1474	72903	18.46	1.734e-05	0.8893
chr3:131778114	rs78818536	CPNE4	T>C	417	22808	18.36	1.828e-05	0.8077

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr20:43235738	rs78824799	PKIG	A>G	1474	11531	26.1	3.245e-07	0.8635
chr15:70339296	rs10083564	-	G>A	1426	11038	21.21	4.123e-06	0.8742
chr14:40572090	rs117604848	-	A>C	432	2334	20.69	5.401e-06	1.271
chr14:63966635	rs73276588	PPP2R5E	A>G	3203	23663	20.46	6.085e-06	0.9113
chr10:111583677	rs72826162	-	T>C	409	3516	19.78	8.691e-06	0.7911
chr21:37408491	rs76492178	AP000688.1	G>C	273	1395	19.71	8.993e-06	1.343
chr3:87318299	rs115735344	POU1F1	G>A	389	2094	19.24	1.15e-05	1.276
chr4:160787840	rs114585534	-	A>G	1139	6795	18.95	1.338e-05	1.154
chr18:23361294	rs7235649	-	A>G	6749	48301	18.73	1.509e-05	0.9333
chr8:101382405	rs77524076	-	T>C	913	7240	18.65	1.572e-05	0.8563
chr6:31862876	rs115062572	EHMT2	C>T	634	3611	18.63	1.588e-05	1.207
chr10:118996115	rs4081624	-	A>C	4851	35148	18.61	1.602e-05	0.9267
chr5:2696353	rs11750155	-	T>C	2947	18609	18.48	1.718e-05	1.096
chr6:31631531	rs114733011	GPANK1	G>A	634	3614	18.4	1.787e-05	1.206
chr11:44886593	rs835749	TSPAN18	C>G	4525	29110	18.33	1.858e-05	1.081
chr15:31428256	rs803534	TRPM1	C>T	6128	39845	18.15	2.038e-05	1.073
chr1:236147660	rs34415891	NID1	C>T	609	4978	18.02	2.191e-05	0.8312
chr11:44884772	rs4755293	TSPAN18	G>A	4820	31094	17.98	2.227e-05	1.078
chr7:42876471	rs77657921	-	G>C	467	2589	17.92	2.31e-05	1.24
chr7:42916582	rs114911199	-	C>T	404	2207	17.55	2.793e-05	1.257

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: J381	Polyp of vocal cord and larynx	1/20
ICD: R05	Cough	1/20
ICD: R061	Stridor	1/20
ICD: T172	Foreign body in pharynx	4/20
ICD: T783	Angioneurotic oedema	5/20

ID	Name	Top Correlation
ICD-10: C320	Glottis	0/20
ICD-10: C329	Larynx, unspecified	0/20
ICD-10: D370	Lip, oral cavity and pharynx	0/20
ICD-10: D381	Trachea, bronchus and lung	0/20
ICD-10: E041	Non-toxic single thyroid nodule	0/20
ICD-10: J040	Acute laryngitis	0/20
ICD-10: J312	Chronic pharyngitis	0/20
ICD-10: J370	Chronic laryngitis	0/20
ICD-10: J380	Paralysis of vocal cords and larynx	0/20
ICD-10: J382	Nodules of vocal cords	0/20
ICD-10: J384	Oedema of larynx	0/20
ICD-10: J387	Other diseases of larynx	0/20
ICD-10: J869	Pyothorax without fistula	0/20
ICD-10: K089	Disorder of teeth and supporting structures, unspecified	0/20
ICD-10: M313	Wegener's granulomatosis	0/20
ICD-10: O698	Labour and delivery complicated by other cord complications	0/20
ICD-10: R066	Hiccough	0/20
ICD-10: R490	Dysphonia	0/20
ICD-10: R498	Other and unspecified voice disturbances	0/20
ICD-10: R845	Abnormal microbiological findings	0/20
ICD-10: T885	Other complications of anaesthesia	0/20

Abnormality of the larynx

0001600

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ