Statistics
| Case | Control |
|---|---|
| 9989 | 450205 |
Phenotype Definition
Reduction inexisting body weight. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32623150 | rs3021302 | - | T>C | 3794 | 157034 | 28.13 | 1.135e-07 | 1.101 |
| chr6:32605884 | rs2187668 | HLA-DQA1 | C>T | 3261 | 134410 | 25.06 | 5.57e-07 | 1.101 |
| chr6:32657436 | rs3129716 | - | T>C | 3302 | 136333 | 24.33 | 8.133e-07 | 1.099 |
| chr2:238069457 | rs114893602 | - | C>T | 598 | 21968 | 23.26 | 1.413e-06 | 1.224 |
| chr1:240015622 | rs78276630 | CHRM3 | G>A | 386 | 21927 | 22.08 | 2.612e-06 | 0.7843 |
| chr6:32659645 | rs2856674 | - | A>G | 3303 | 137095 | 21.79 | 3.042e-06 | 1.094 |
| chr2:238143156 | rs72979880 | - | T>C | 621 | 23083 | 21.3 | 3.933e-06 | 1.209 |
| chr16:27327201 | rs113001936 | IL4R | G>A | 313 | 10782 | 21.17 | 4.211e-06 | 1.303 |
| chr6:31346621 | rs2442736 | - | G>C | 5129 | 216838 | 21.1 | 4.363e-06 | 1.077 |
| chr10:135259493 | rs114219906 | - | C>T | 458 | 16598 | 20.29 | 6.664e-06 | 1.24 |
| chr6:32666526 | rs1794282 | - | C>T | 2798 | 115622 | 19.95 | 7.967e-06 | 1.096 |
| chr1:34375199 | rs911216 | CSMD2 | A>C | 4170 | 198582 | 19.85 | 8.38e-06 | 0.9252 |
| chr11:20091167 | rs35805981 | NAV2 | G>A | 3096 | 128601 | 19.51 | 9.998e-06 | 1.091 |
| chr16:83706465 | rs6563962 | CDH13 | C>T | 5941 | 253036 | 19.43 | 1.041e-05 | 1.07 |
| chr9:82421342 | rs116043877 | - | A>G | 326 | 11404 | 19.42 | 1.051e-05 | 1.282 |
| chr13:95541747 | rs9516487 | - | A>G | 9278 | 400963 | 19.22 | 1.163e-05 | 1.063 |
| chr7:20224363 | rs3095222 | MACC1 | G>C | 10581 | 459612 | 19.01 | 1.298e-05 | 1.062 |
| chr6:32303692 | rs1265754 | TSBP1 | T>A | 2837 | 117543 | 18.81 | 1.441e-05 | 1.093 |
| chr19:45410002 | rs769449 | APOE | G>A | 2778 | 115142 | 18.66 | 1.563e-05 | 1.093 |
| chr14:42190344 | rs28778645 | LRFN5 | T>C | 6988 | 300054 | 18.63 | 1.586e-05 | 1.066 |
| chr6:32623150 | rs3021302 | - | T>C | 3585 | 148933 | 28.68 | 8.519e-08 | 1.105 |
| chr6:32605884 | rs2187668 | HLA-DQA1 | C>T | 3117 | 129000 | 26.33 | 2.879e-07 | 1.107 |
| chr6:32657436 | rs3129716 | - | T>C | 3166 | 131059 | 25.91 | 3.578e-07 | 1.105 |
| chr6:32659645 | rs2856674 | - | A>G | 3168 | 131690 | 23.89 | 1.02e-06 | 1.101 |
| chr6:32666526 | rs1794282 | - | C>T | 2773 | 114504 | 23.85 | 1.042e-06 | 1.106 |
| chr2:238069457 | rs114893602 | - | C>T | 585 | 21569 | 23.53 | 1.23e-06 | 1.229 |
| chr6:32303692 | rs1265754 | TSBP1 | T>A | 2810 | 116387 | 22.38 | 2.232e-06 | 1.102 |
| chr16:27327201 | rs113001936 | IL4R | G>A | 308 | 10591 | 22.24 | 2.404e-06 | 1.315 |
| chr19:45410002 | rs769449 | APOE | G>A | 2705 | 111975 | 22.12 | 2.565e-06 | 1.103 |
| chr6:31430694 | rs3094605 | - | G>C | 3049 | 126881 | 22.11 | 2.573e-06 | 1.098 |
| chr6:32302382 | rs1265757 | TSBP1 | C>T | 2800 | 116101 | 21.58 | 3.395e-06 | 1.1 |
| chr6:32310863 | rs2849018 | TSBP1 | T>C | 2804 | 116386 | 21.48 | 3.567e-06 | 1.1 |
| chr6:32325562 | rs2395149 | TSBP1 | G>A | 2802 | 116250 | 21.47 | 3.598e-06 | 1.1 |
| chr6:31434366 | rs3094013 | - | G>A | 3046 | 126920 | 21.3 | 3.928e-06 | 1.096 |
| chr6:32408497 | rs3135394 | HLA-DRA | A>G | 2791 | 115843 | 21.25 | 4.033e-06 | 1.1 |
| chr6:32261252 | rs7775397 | TSBP1 | T>G | 2802 | 116320 | 21.24 | 4.047e-06 | 1.1 |
| chr6:32333827 | rs3129927 | TSBP1 | A>C | 2803 | 116346 | 21.15 | 4.247e-06 | 1.099 |
| chr6:31434621 | rs3131618 | - | A>G | 3031 | 126304 | 21.13 | 4.291e-06 | 1.096 |
| chr6:31312326 | rs3134792 | HLA-B | T>G | 3103 | 129489 | 21.03 | 4.531e-06 | 1.095 |
| chr6:31306420 | rs1625792 | HLA-B | G>A | 3039 | 126605 | 21.02 | 4.536e-06 | 1.096 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32659645 | rs2856674 | - | A>G | 3303 | 2780 | 895.4 | 9.844e-197 | 0.4184 |
| chr6:32657436 | rs3129716 | - | T>C | 3302 | 2767 | 881.1 | 1.268e-193 | 0.4211 |
| chr6:32605884 | rs2187668 | HLA-DQA1 | C>T | 3261 | 2715 | 856.3 | 3.149e-188 | 0.4235 |
| chr6:32408497 | rs3135394 | HLA-DRA | A>G | 2818 | 2464 | 844.8 | 9.861e-186 | 0.4122 |
| chr6:32666526 | rs1794282 | - | C>T | 2798 | 2449 | 842.1 | 3.774e-185 | 0.4119 |
| chr6:32345689 | rs2894254 | - | T>G | 2808 | 2454 | 842.1 | 3.853e-185 | 0.4122 |
| chr6:32395726 | rs3129843 | - | A>G | 2802 | 2442 | 835.4 | 1.08e-183 | 0.4131 |
| chr6:32631348 | rs9274253 | HLA-DQB1 | G>A | 5540 | 3890 | 828.0 | 4.394e-182 | 0.4719 |
| chr6:32634467 | rs3891175 | HLA-DQB1 | C>T | 5515 | 3866 | 824.5 | 2.526e-181 | 0.4723 |
| chr6:32628698 | rs9273529 | HLA-DQB1 | C>T | 5557 | 3886 | 821.6 | 1.094e-180 | 0.4737 |
| chr6:32290208 | rs9268235 | TSBP1 | C>T | 2854 | 2460 | 817.2 | 9.902e-180 | 0.4186 |
| chr6:32310863 | rs2849018 | TSBP1 | T>C | 2832 | 2446 | 813.7 | 5.807e-179 | 0.4186 |
| chr6:32333827 | rs3129927 | TSBP1 | A>C | 2830 | 2445 | 812.7 | 9.158e-179 | 0.4188 |
| chr6:32261252 | rs7775397 | TSBP1 | T>G | 2829 | 2442 | 811.8 | 1.483e-178 | 0.4189 |
| chr6:32325562 | rs2395149 | TSBP1 | G>A | 2829 | 2441 | 811.5 | 1.663e-178 | 0.4189 |
| chr6:32194630 | rs3096690 | - | G>C | 2883 | 2468 | 808.0 | 9.747e-178 | 0.4215 |
| chr6:32303692 | rs1265754 | TSBP1 | T>A | 2837 | 2441 | 806.4 | 2.187e-177 | 0.4201 |
| chr6:32302382 | rs1265757 | TSBP1 | C>T | 2827 | 2435 | 806.1 | 2.593e-177 | 0.4199 |
| chr6:32603007 | rs2040406 | HLA-DQA1 | A>G | 3922 | 3030 | 785.0 | 9.883e-173 | 0.4554 |
| chr6:32080191 | rs1269852 | TNXB | G>C | 2797 | 2390 | 770.4 | 1.504e-169 | 0.426 |
| chr6:32659645 | rs2856674 | - | A>G | 3168 | 2690 | 900.5 | 7.648e-198 | 0.4088 |
| chr6:32657436 | rs3129716 | - | T>C | 3166 | 2678 | 887.8 | 4.342e-195 | 0.4112 |
| chr6:32605884 | rs2187668 | HLA-DQA1 | C>T | 3117 | 2625 | 867.2 | 1.314e-190 | 0.4124 |
| chr6:32408497 | rs3135394 | HLA-DRA | A>G | 2791 | 2443 | 857.7 | 1.551e-188 | 0.4047 |
| chr6:32666526 | rs1794282 | - | C>T | 2773 | 2430 | 855.2 | 5.452e-188 | 0.4045 |
| chr6:32345689 | rs2894254 | - | T>G | 2781 | 2434 | 854.6 | 7.251e-188 | 0.4048 |
| chr6:32395726 | rs3129843 | - | A>G | 2777 | 2421 | 846.4 | 4.367e-186 | 0.406 |
| chr6:32631348 | rs9274253 | HLA-DQB1 | G>A | 5246 | 3725 | 843.2 | 2.203e-185 | 0.458 |
| chr6:32628698 | rs9273529 | HLA-DQB1 | C>T | 5271 | 3723 | 833.3 | 3.125e-183 | 0.4605 |
| chr6:32634467 | rs3891175 | HLA-DQB1 | C>T | 5248 | 3709 | 832.2 | 5.312e-183 | 0.4604 |
| chr6:32290208 | rs9268235 | TSBP1 | C>T | 2827 | 2437 | 827.1 | 6.757e-182 | 0.4115 |
| chr6:32333827 | rs3129927 | TSBP1 | A>C | 2803 | 2423 | 823.3 | 4.752e-181 | 0.4117 |
| chr6:32310863 | rs2849018 | TSBP1 | T>C | 2804 | 2422 | 822.5 | 6.827e-181 | 0.4118 |
| chr6:32325562 | rs2395149 | TSBP1 | G>A | 2802 | 2419 | 821.6 | 1.073e-180 | 0.4119 |
| chr6:32261252 | rs7775397 | TSBP1 | T>G | 2802 | 2420 | 821.2 | 1.314e-180 | 0.412 |
| chr6:32194630 | rs3096690 | - | G>C | 2852 | 2444 | 820.0 | 2.467e-180 | 0.4139 |
| chr6:32302382 | rs1265757 | TSBP1 | C>T | 2800 | 2413 | 816.6 | 1.32e-179 | 0.4128 |
| chr6:32303692 | rs1265754 | TSBP1 | T>A | 2810 | 2418 | 815.7 | 2.089e-179 | 0.4133 |
| chr6:32603007 | rs2040406 | HLA-DQA1 | A>G | 3697 | 2910 | 808.5 | 7.6e-178 | 0.4402 |
| chr6:32080191 | rs1269852 | TNXB | G>C | 2773 | 2371 | 781.5 | 5.82e-172 | 0.4189 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: R634 | Abnormal weight loss | 9/20 |