Statistics
| Case | Control |
|---|---|
| 3168 | 457026 |
Phenotype Definition
Increased count of eosinophils in the blood. [HPO:sdoelken]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr17:9741032 | rs4239109 | GLP2R | T>C | 435 | 79537 | 24.72 | 6.622e-07 | 0.7814 |
| chr19:32582254 | rs147138724 | - | C>A | 129 | 12268 | 23.76 | 1.09e-06 | 1.541 |
| chr6:158856783 | rs341112 | TULP4 | C>T | 2397 | 322412 | 22.19 | 2.465e-06 | 1.128 |
| chr8:62220431 | rs2931298 | CLVS1 | A>G | 428 | 49831 | 22.15 | 2.52e-06 | 1.266 |
| chr2:60914729 | rs17031887 | - | T>C | 1541 | 201615 | 21.59 | 3.38e-06 | 1.145 |
| chr12:18706024 | rs12318497 | PIK3C2G | A>G | 112 | 24959 | 21.08 | 4.41e-06 | 0.6472 |
| chr11:127291567 | rs2169833 | - | T>C | 1424 | 231035 | 20.98 | 4.652e-06 | 0.8716 |
| chr8:144107977 | rs10283236 | - | G>A | 528 | 92864 | 20.94 | 4.735e-06 | 0.8121 |
| chr15:88035882 | rs74028746 | - | T>C | 994 | 165181 | 20.82 | 5.041e-06 | 0.8545 |
| chr2:70187 | rs10170011 | - | G>A | 537 | 64705 | 20.64 | 5.557e-06 | 1.228 |
| chr1:94509224 | rs4847272 | ABCA4 | A>G | 191 | 20098 | 20.46 | 6.086e-06 | 1.394 |
| chr2:152676741 | rs16830400 | ARL5A | G>C | 252 | 27730 | 20.39 | 6.3e-06 | 1.337 |
| chr7:11705375 | rs62434554 | THSD7A | G>A | 540 | 94275 | 19.84 | 8.435e-06 | 0.8184 |
| chr1:65860660 | rs12077111 | DNAJC6 | T>C | 123 | 26508 | 19.5 | 1.006e-05 | 0.6702 |
| chr11:93577817 | rs11826139 | VSTM5 | C>T | 202 | 39765 | 19.35 | 1.086e-05 | 0.7306 |
| chr3:78554086 | rs114791774 | - | A>G | 231 | 25266 | 19.29 | 1.123e-05 | 1.342 |
| chr21:32473934 | rs8129586 | - | A>T | 614 | 105640 | 19.12 | 1.228e-05 | 0.8307 |
| chr18:55425076 | rs28651604 | ATP8B1 | A>C | 466 | 82198 | 18.88 | 1.395e-05 | 0.8114 |
| chr1:65858151 | rs11208644 | DNAJC6 | C>T | 124 | 26366 | 18.44 | 1.758e-05 | 0.6786 |
| chr16:89898764 | rs6500457 | SPIRE2 | C>G | 2821 | 385972 | 18.42 | 1.776e-05 | 1.113 |
| chr8:62220431 | rs2931298 | CLVS1 | A>G | 427 | 49015 | 23.25 | 1.42e-06 | 1.274 |
| chr19:32582254 | rs147138724 | - | C>A | 128 | 12139 | 22.93 | 1.683e-06 | 1.532 |
| chr7:11705375 | rs62434554 | THSD7A | G>A | 496 | 87548 | 22.38 | 2.236e-06 | 0.8012 |
| chr6:41372215 | rs114547730 | - | T>G | 84 | 7327 | 21.76 | 3.085e-06 | 1.665 |
| chr18:55425076 | rs28651604 | ATP8B1 | A>C | 441 | 78071 | 20.29 | 6.652e-06 | 0.8004 |
| chr4:63341366 | rs13134351 | - | C>T | 2604 | 351224 | 20.15 | 7.15e-06 | 1.122 |
| chr1:94509224 | rs4847272 | ABCA4 | A>G | 180 | 18675 | 19.93 | 8.04e-06 | 1.402 |
| chr11:129503398 | rs117937738 | - | G>A | 205 | 21854 | 19.25 | 1.147e-05 | 1.366 |
| chr3:185151885 | rs1017502 | MAP3K13 | C>T | 958 | 121093 | 19.2 | 1.177e-05 | 1.167 |
| chr11:76898338 | rs10437740 | MYO7A | C>T | 584 | 70825 | 18.92 | 1.36e-05 | 1.209 |
| chr7:11742920 | rs9785045 | THSD7A | T>G | 565 | 96852 | 18.76 | 1.486e-05 | 0.8259 |
| chr11:127291567 | rs2169833 | - | T>C | 1307 | 209877 | 18.52 | 1.684e-05 | 0.8745 |
| chr7:136095212 | rs17168660 | - | T>C | 342 | 39339 | 18.29 | 1.9e-05 | 1.269 |
| chr2:152676741 | rs16830400 | ARL5A | G>C | 238 | 26153 | 18.27 | 1.913e-05 | 1.327 |
| chr3:78554086 | rs114791774 | - | A>G | 228 | 24870 | 18.26 | 1.923e-05 | 1.335 |
| chr2:70187 | rs10170011 | - | G>A | 526 | 63467 | 18.17 | 2.021e-05 | 1.215 |
| chr17:7814099 | rs12950420 | CHD3 | T>C | 455 | 54156 | 18.08 | 2.121e-05 | 1.23 |
| chr6:88593579 | rs9359760 | - | C>T | 1295 | 168126 | 17.89 | 2.344e-05 | 1.141 |
| chr20:10906653 | rs1232582 | - | T>C | 422 | 49877 | 17.85 | 2.395e-05 | 1.238 |
| chr11:123415164 | rs1290815 | GRAMD1B | G>A | 592 | 72299 | 17.71 | 2.568e-05 | 1.2 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32605699 | rs111541957 | HLA-DQA1 | G>A | 737 | 204 | 24.66 | 6.839e-07 | 1.506 |
| chr6:32504136 | rs66525318 | - | C>A | 831 | 238 | 23.68 | 1.138e-06 | 1.456 |
| chr6:32665420 | rs10484561 | - | T>G | 767 | 215 | 23.65 | 1.152e-06 | 1.48 |
| chr6:32549638 | rs72850244 | HLA-DRB1 | G>A | 770 | 218 | 23.22 | 1.443e-06 | 1.472 |
| chr17:9741032 | rs4239109 | GLP2R | T>C | 362 | 215 | 22.81 | 1.789e-06 | 0.6538 |
| chr15:70018990 | rs7176508 | - | G>A | 2370 | 1082 | 22.45 | 2.158e-06 | 0.7972 |
| chr6:32550580 | rs35662241 | HLA-DRB1 | C>T | 716 | 199 | 22.43 | 2.178e-06 | 1.486 |
| chr6:32590844 | rs17533167 | - | G>C | 767 | 218 | 22.25 | 2.393e-06 | 1.46 |
| chr6:32542638 | rs34451186 | - | T>C | 771 | 221 | 21.68 | 3.226e-06 | 1.45 |
| chr2:26797358 | rs75168184 | FAM166C | G>A | 73 | 63 | 21.38 | 3.761e-06 | 0.4568 |
| chr6:32553626 | rs113647600 | HLA-DRB1 | C>A | 772 | 222 | 21.32 | 3.878e-06 | 1.445 |
| chr6:32583188 | rs113979555 | - | G>A | 767 | 221 | 21.07 | 4.427e-06 | 1.443 |
| chr6:32548469 | rs3830133 | HLA-DRB1 | A>G | 772 | 223 | 21.06 | 4.446e-06 | 1.441 |
| chr6:32527079 | rs28530648 | - | A>C | 803 | 234 | 20.66 | 5.494e-06 | 1.426 |
| chr22:45731731 | rs2205660 | FAM118A | A>G | 734 | 382 | 20.63 | 5.584e-06 | 0.7348 |
| chr6:32581889 | rs4530903 | - | C>T | 757 | 219 | 20.12 | 7.291e-06 | 1.433 |
| chr22:45757987 | rs5764704 | SMC1B | T>C | 732 | 381 | 19.99 | 7.793e-06 | 0.7382 |
| chr12:68882906 | rs12426108 | - | T>C | 125 | 91 | 19.94 | 7.979e-06 | 0.5404 |
| chr10:55955610 | rs10825269 | PCDH15 | C>T | 737 | 383 | 19.88 | 8.242e-06 | 0.7393 |
| chr17:67497411 | rs17763881 | MAP2K6 | C>T | 239 | 150 | 19.88 | 8.257e-06 | 0.6232 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: C772 | Intra-abdominal lymph nodes | 4/20 |