Statistics
| Case | Control |
|---|---|
| 1130 | 459064 |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr19:30873795 | rs113344036 | ZNF536 | A>G | 102 | 25504 | 25.47 | 4.495e-07 | 1.659 |
| chr1:222464646 | rs77054023 | - | A>G | 67 | 15103 | 24.44 | 7.685e-07 | 1.831 |
| chr5:136984755 | rs80072977 | KLHL3 | T>G | 97 | 24601 | 22.75 | 1.846e-06 | 1.633 |
| chr12:82399734 | rs78743637 | - | C>T | 345 | 110931 | 21.88 | 2.906e-06 | 1.312 |
| chr6:115195868 | rs7741124 | - | C>T | 242 | 130416 | 20.91 | 4.808e-06 | 0.7339 |
| chr1:53860219 | rs11577494 | - | A>G | 112 | 30226 | 20.07 | 7.462e-06 | 1.539 |
| chr3:36142512 | rs17829662 | - | T>C | 379 | 124569 | 20.02 | 7.678e-06 | 1.284 |
| chr19:40092547 | rs79307501 | - | C>G | 86 | 21842 | 19.96 | 7.896e-06 | 1.627 |
| chr14:94400394 | rs113402958 | - | C>T | 192 | 57625 | 19.45 | 1.032e-05 | 1.392 |
| chr10:30731411 | rs7071698 | MAP3K8 | A>G | 175 | 97655 | 19.41 | 1.054e-05 | 0.7085 |
| chr2:192615511 | rs77652784 | - | C>T | 125 | 34657 | 19.33 | 1.098e-05 | 1.495 |
| chr12:131024990 | rs77507082 | RIMBP2 | G>C | 55 | 12550 | 19.32 | 1.105e-05 | 1.808 |
| chr6:36234176 | rs11753002 | PNPLA1 | T>C | 122 | 72633 | 19.09 | 1.247e-05 | 0.6678 |
| chr4:112159676 | rs72676716 | - | G>A | 201 | 61027 | 19.02 | 1.292e-05 | 1.378 |
| chr3:22635096 | rs13085456 | - | T>C | 62 | 14766 | 18.86 | 1.41e-05 | 1.738 |
| chr7:28497994 | rs9791570 | CREB5 | T>G | 656 | 230848 | 18.82 | 1.437e-05 | 1.22 |
| chr3:31667308 | rs113140483 | STT3B | A>G | 79 | 19983 | 18.74 | 1.5e-05 | 1.634 |
| chr15:80566573 | rs2866597 | - | G>A | 976 | 357774 | 18.68 | 1.546e-05 | 1.198 |
| chr12:52961710 | rs79199336 | KRT74 | G>A | 382 | 126778 | 18.66 | 1.561e-05 | 1.273 |
| chr1:222551916 | rs76841236 | - | G>A | 81 | 20638 | 18.63 | 1.591e-05 | 1.623 |
| chr19:30873795 | rs113344036 | ZNF536 | A>G | 101 | 25055 | 25.66 | 4.073e-07 | 1.667 |
| chr12:82399734 | rs78743637 | - | C>T | 329 | 103709 | 23.72 | 1.113e-06 | 1.336 |
| chr1:222464646 | rs77054023 | - | A>G | 66 | 14908 | 23.58 | 1.199e-06 | 1.82 |
| chr6:36234176 | rs11753002 | PNPLA1 | T>C | 104 | 65863 | 22.46 | 2.148e-06 | 0.6239 |
| chr5:136984755 | rs80072977 | KLHL3 | T>G | 96 | 24289 | 22.38 | 2.237e-06 | 1.631 |
| chr10:30731411 | rs7071698 | MAP3K8 | A>G | 139 | 82372 | 22.15 | 2.521e-06 | 0.6639 |
| chr17:3553526 | rs161350 | CTNS | G>A | 11 | 1196 | 21.86 | 2.936e-06 | 3.748 |
| chr6:115195868 | rs7741124 | - | C>T | 237 | 127927 | 21.38 | 3.76e-06 | 0.7285 |
| chr25:1238328 | rs73614126 | - | A>G | 405 | 133177 | 20.85 | 4.972e-06 | 1.284 |
| chr8:124865217 | Affx-31498854 | FER1L6 | C>A | 76 | 18484 | 20.67 | 5.454e-06 | 1.691 |
| chr5:85168242 | rs73144616 | - | C>A | 74 | 17976 | 20.35 | 6.445e-06 | 1.696 |
| chr12:52961710 | rs79199336 | KRT74 | G>A | 365 | 119011 | 20.33 | 6.521e-06 | 1.294 |
| chr12:131024990 | rs77507082 | RIMBP2 | G>C | 55 | 12406 | 19.79 | 8.623e-06 | 1.822 |
| chr1:53860219 | rs11577494 | - | A>G | 109 | 29351 | 19.31 | 1.113e-05 | 1.536 |
| chr2:192615511 | rs77652784 | - | C>T | 121 | 33249 | 19.22 | 1.167e-05 | 1.503 |
| chr15:80566573 | rs2866597 | - | G>A | 951 | 346074 | 19.08 | 1.253e-05 | 1.205 |
| chr10:34957570 | rs78009943 | PARD3 | C>T | 127 | 35465 | 19.01 | 1.298e-05 | 1.487 |
| chr2:115080598 | rs952595 | - | C>T | 138 | 39024 | 19.0 | 1.309e-05 | 1.464 |
| chr14:94400394 | rs113402958 | - | C>T | 189 | 56650 | 18.86 | 1.408e-05 | 1.39 |
| chr9:89189773 | rs72752765 | - | C>T | 278 | 88329 | 18.75 | 1.488e-05 | 1.319 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr19:30873795 | rs113344036 | ZNF536 | A>G | 101 | 509 | 27.58 | 1.508e-07 | 1.78 |
| chr5:136984755 | rs80072977 | KLHL3 | T>G | 96 | 484 | 26.1 | 3.237e-07 | 1.777 |
| chr17:32012187 | rs8071384 | ASIC2 | A>G | 982 | 9706 | 24.05 | 9.384e-07 | 0.803 |
| chr17:32011978 | rs8069370 | ASIC2 | G>A | 661 | 6814 | 22.69 | 1.905e-06 | 0.7935 |
| chr12:131024990 | rs77507082 | RIMBP2 | G>C | 55 | 246 | 21.72 | 3.161e-06 | 1.993 |
| chr7:141721639 | rs2272327 | MGAM | G>A | 40 | 160 | 21.21 | 4.122e-06 | 2.224 |
| chr1:222464646 | rs77054023 | - | A>G | 66 | 316 | 21.15 | 4.243e-06 | 1.861 |
| chr6:115195868 | rs7741124 | - | C>T | 237 | 2796 | 21.08 | 4.399e-06 | 0.7205 |
| chr6:36234176 | rs11753002 | PNPLA1 | T>C | 104 | 1422 | 20.62 | 5.612e-06 | 0.6259 |
| chr4:112159676 | rs72676716 | - | G>A | 198 | 1254 | 20.25 | 6.78e-06 | 1.43 |
| chr10:30731411 | rs7071698 | MAP3K8 | A>G | 139 | 1780 | 20.24 | 6.825e-06 | 0.6657 |
| chr5:85168242 | rs73144616 | - | C>A | 74 | 374 | 19.96 | 7.893e-06 | 1.768 |
| chr12:82399734 | rs78743637 | - | C>T | 329 | 2260 | 19.91 | 8.127e-06 | 1.328 |
| chr3:118124359 | rs114740671 | - | T>C | 65 | 317 | 19.76 | 8.783e-06 | 1.83 |
| chr10:123992227 | rs4366423 | TACC2 | C>T | 30 | 109 | 19.76 | 8.782e-06 | 2.441 |
| chr7:28497994 | rs9791570 | CREB5 | T>G | 624 | 4668 | 19.22 | 1.168e-05 | 1.244 |
| chr21:37872203 | rs117356573 | CLDN14 | C>T | 65 | 323 | 18.49 | 1.71e-05 | 1.794 |
| chr1:53860219 | rs11577494 | - | A>G | 109 | 621 | 18.45 | 1.743e-05 | 1.573 |
| chr9:34329839 | rs2039345 | NUDT2 | C>G | 535 | 3948 | 18.25 | 1.933e-05 | 1.251 |
| chr3:22635096 | rs13085456 | - | T>C | 61 | 300 | 18.14 | 2.056e-05 | 1.817 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: A415 | Septicaemia due to other Gram-negative organisms | 4/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: N321 | Vesicointestinal fistula | 0/20 |