Emphysema

0002097

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

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Statistics

Case	Control
13622	446572

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr15:48426484	rs1426654	SLC24A5	A>G	380	27146	230.3	5.049e-52	0.4629
chr15:48392165	rs1834640	-	A>G	508	31116	192.0	1.145e-43	0.5402
chr5:33951693	rs16891982	SLC45A2	G>C	1366	65692	187.1	1.342e-42	0.6831
chr5:33958959	rs28777	SLC45A2	A>C	1131	55861	177.0	2.238e-40	0.6669
chr23:71628912	rs3012642	AL133500.1	A>G	308	22416	165.3	7.962e-38	0.4833
chr1:159174683	rs2814778	ACKR1	T>C	274	19103	153.6	2.843e-35	0.4767
chr6:136480972	rs9483910	PDE7B	C>T	323	21047	148.3	4.178e-34	0.5097
chr2:171380643	rs34020565	MYO3B	T>G	405	24454	144.3	3.116e-33	0.5503
chr6:170242949	rs9396958	-	T>C	219	15895	136.5	1.562e-31	0.4592
chr5:147863034	rs9325101	HTR4	A>G	234	16506	135.2	3e-31	0.4719
chr2:66725070	rs12995572	MEIS1	G>C	472	26679	131.7	1.714e-30	0.5878
chr9:127267689	rs3814134	NR5A1	A>G	522	28684	130.7	2.923e-30	0.6039
chr5:147671850	rs7724380	-	G>A	317	19866	128.0	1.146e-29	0.5307
chr8:145639681	rs1871534	SLC39A4	G>C	272	17873	127.7	1.285e-29	0.5063
chr2:3313043	rs73133173	EIPR1	A>C	193	14270	126.5	2.351e-29	0.4508
chr19:42393286	rs717225	ARHGEF1	A>G	361	21582	124.2	7.705e-29	0.5561
chr23:128718936	rs2362937	OCRL	T>C	291	19660	123.3	1.173e-28	0.5225
chr6:144665357	rs6917261	UTRN	T>C	168	12947	122.5	1.787e-28	0.4328
chr17:29350769	rs8073072	-	T>G	450	25256	122.3	1.937e-28	0.5919
chr6:3185712	rs7754077	-	C>T	289	18383	122.1	2.198e-28	0.5235
chr15:78898723	rs12914385	CHRNA3	C>T	11063	339790	73.61	9.505e-18	1.113
chr15:78911181	rs8040868	CHRNA3	T>C	11333	349413	67.99	1.64e-16	1.108
chr15:78802869	rs9788721	HYKK	T>C	9870	302707	64.55	9.427e-16	1.108
chr15:78878541	rs951266	CHRNA5	G>A	9579	293493	63.1	1.965e-15	1.108
chr15:78873993	rs7180002	CHRNA5	A>T	9579	293406	62.83	2.257e-15	1.108
chr15:78882925	rs16969968	CHRNA5	G>A	9602	294342	62.82	2.268e-15	1.107
chr15:78911672	rs4243084	CHRNA3	G>C	9742	299131	62.58	2.562e-15	1.107
chr15:78806023	rs8034191	HYKK	T>C	9713	297816	62.57	2.572e-15	1.107
chr15:78894339	rs1051730	CHRNA3	G>A	9592	293988	62.4	2.8e-15	1.107
chr15:78814046	rs10519203	HYKK	A>G	9750	299198	62.02	3.397e-15	1.106
chr15:78867482	rs17486278	CHRNA5	A>C	9601	294620	61.21	5.129e-15	1.106
chr4:145480780	rs1828591	AC098588.2	A>G	10120	352663	61.16	5.249e-15	0.9053
chr15:78754000	rs1964678	IREB2	G>A	9782	341671	61.15	5.297e-15	0.9046
chr15:78826180	rs931794	HYKK	A>G	9732	298957	60.9	6.009e-15	1.105
chr4:145474473	rs1489759	AC098588.2	A>G	10086	351438	60.56	7.127e-15	0.9055
chr15:78789488	rs13180	IREB2	T>C	9846	343414	60.34	7.997e-15	0.9054
chr4:145506456	rs13141641	AC098588.2	T>C	10080	351228	59.75	1.079e-14	0.9062
chr15:78774271	rs8042238	IREB2	T>C	9843	343318	59.57	1.181e-14	0.9059
chr4:145479761	rs6537293	AC098588.2	A>G	10109	351960	59.1	1.501e-14	0.9067
chr15:78857939	rs55853698	CHRNA5	T>G	9688	297755	59.01	1.569e-14	1.104

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr15:48426484	rs1426654	SLC24A5	A>G	380	4643	166.2	4.91e-38	0.5066
chr23:71628912	rs3012642	AL133500.1	A>G	308	4101	150.6	1.263e-34	0.4887
chr5:33951693	rs16891982	SLC45A2	G>C	1366	11950	146.7	9.212e-34	0.7024
chr5:33958959	rs28777	SLC45A2	A>C	1131	10220	145.3	1.893e-33	0.6814
chr15:48392165	rs1834640	-	A>G	508	5417	137.8	7.885e-32	0.5807
chr1:159174683	rs2814778	ACKR1	T>C	274	3452	131.0	2.489e-30	0.4929
chr6:136480972	rs9483910	PDE7B	C>T	323	3769	121.0	3.821e-28	0.5319
chr2:171380643	rs34020565	MYO3B	T>G	405	4385	115.7	5.51e-27	0.5735
chr2:66725070	rs12995572	MEIS1	G>C	472	4913	115.6	5.681e-27	0.5962
chr5:147863034	rs9325101	HTR4	A>G	234	2900	106.0	7.505e-25	0.502
chr17:29350769	rs8073072	-	T>G	450	4634	105.6	9.168e-25	0.6027
chr23:64367019	rs7064929	-	G>A	260	3269	105.5	9.557e-25	0.5195
chr8:145639681	rs1871534	SLC39A4	G>C	272	3198	104.3	1.782e-24	0.5286
chr17:29298304	rs7225888	RNF135	C>G	318	3572	103.9	2.156e-24	0.5535
chr9:127267689	rs3814134	NR5A1	A>G	522	5151	101.9	5.701e-24	0.6286
chr6:144665357	rs6917261	UTRN	T>C	168	2303	101.7	6.439e-24	0.4547
chr19:42393286	rs717225	ARHGEF1	A>G	361	3881	100.5	1.166e-23	0.5777
chr16:28995057	rs11859822	SPNS1	T>C	540	5272	100.3	1.335e-23	0.6355
chr6:3185712	rs7754077	-	C>T	289	3302	100.1	1.439e-23	0.5445
chr23:128718936	rs2362937	OCRL	T>C	291	3484	99.81	1.677e-23	0.546
chr15:78898723	rs12914385	CHRNA3	C>T	11063	63589	61.8	3.794e-15	1.11
chr15:78911181	rs8040868	CHRNA3	T>C	11333	65406	56.55	5.47e-14	1.105
chr15:78911672	rs4243084	CHRNA3	G>C	9742	55909	54.72	1.386e-13	1.106
chr15:78878541	rs951266	CHRNA5	G>A	9579	54904	53.69	2.346e-13	1.106
chr15:78882925	rs16969968	CHRNA5	G>A	9602	55068	53.53	2.543e-13	1.106
chr15:78873993	rs7180002	CHRNA5	A>T	9579	54890	53.39	2.732e-13	1.106
chr15:78894339	rs1051730	CHRNA3	G>A	9592	55003	53.12	3.144e-13	1.105
chr15:78867482	rs17486278	CHRNA5	A>C	9601	55114	52.14	5.169e-13	1.104
chr15:78802869	rs9788721	HYKK	T>C	9870	56766	51.34	7.772e-13	1.103
chr4:145474473	rs1489759	AC098588.2	A>G	10086	65568	50.89	9.781e-13	0.908
chr4:145480780	rs1828591	AC098588.2	A>G	10120	65770	50.66	1.1e-12	0.9083
chr15:78806023	rs8034191	HYKK	T>C	9713	55831	50.09	1.466e-12	1.102
chr15:78868636	rs72740964	CHRNA5	G>A	9460	54367	49.47	2.016e-12	1.102
chr15:78896129	rs1317286	CHRNA3	A>G	9655	55528	49.27	2.227e-12	1.101
chr4:145479761	rs6537293	AC098588.2	A>G	10109	65661	49.24	2.262e-12	0.9095
chr15:78814046	rs10519203	HYKK	A>G	9750	56100	49.01	2.543e-12	1.1
chr4:145486389	rs13118928	AC098588.2	A>G	10102	65639	48.45	3.385e-12	0.9102
chr15:78826180	rs931794	HYKK	A>G	9732	56062	48.07	4.119e-12	1.099
chr4:145460230	rs13147758	AC098588.2	A>G	10091	65437	48.03	4.197e-12	0.9106
chr15:78857939	rs55853698	CHRNA5	T>G	9688	55783	47.82	4.682e-12	1.099

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: J439	Emphysema, unspecified	1/20
ICD: J448	Other specified chronic obstructive pulmonary disease	1/20
ICD: J449	Chronic obstructive pulmonary disease, unspecified	14/20

ID	Name	Top Correlation
ICD-10: D381	Trachea, bronchus and lung	0/20
ICD-10: J40	Bronchitis, not specified as acute or chronic	0/20
ICD-10: J42	Unspecified chronic bronchitis	0/20
ICD-10: J432	Centrilobular emphysema	0/20
ICD-10: T797	Traumatic subcutaneous emphysema	0/20

Emphysema

0002097

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ