Colonic diverticula

0002253

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

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Interactive Plot

Statistics

Case	Control
43860	416334

Phenotype Definition

The presence of multiple diverticula of the colon. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	4262	62796	734.5	9.489e-162	0.6463
chr15:48426484	rs1426654	SLC24A5	A>G	1312	26214	687.3	1.702e-151	0.4813
chr5:33958959	rs28777	SLC45A2	A>C	3573	53419	653.7	3.482e-144	0.6392
chr15:48392165	rs1834640	-	A>G	1673	29951	619.4	1.026e-136	0.5371
chr5:33955326	rs35390	SLC45A2	A>C	2620	38527	434.1	2.094e-96	0.6544
chr5:33955673	rs35391	SLC45A2	C>T	2608	38372	433.4	3.025e-96	0.6541
chr5:33951116	rs35397	SLC45A2	T>G	6645	83463	431.1	9.327e-96	0.76
chr9:129557967	rs7863211	-	G>A	1000	18202	386.8	4.135e-86	0.5315
chr1:159174683	rs2814778	ACKR1	T>C	1018	18359	381.4	6.134e-85	0.5366
chr6:3185712	rs7754077	-	C>T	970	17702	378.4	2.768e-84	0.5302
chr16:28995057	rs11859822	SPNS1	T>C	1783	27653	375.5	1.2e-83	0.6225
chr19:42393286	rs717225	ARHGEF1	A>G	1227	20716	363.5	4.829e-81	0.5729
chr2:171380643	rs34020565	MYO3B	T>G	1465	23394	348.3	9.958e-78	0.6055
chr5:147671850	rs7724380	-	G>A	1117	19066	344.2	7.614e-77	0.567
chr16:28954860	rs7203982	-	T>C	1821	27561	343.0	1.401e-76	0.6382
chr23:128718936	rs2362937	OCRL	T>C	1082	18869	341.0	3.909e-76	0.5631
chr19:42392441	rs16975619	ARHGEF1	T>C	1112	18898	337.0	2.807e-75	0.5696
chr15:45491394	rs1648299	SHF	T>C	904	16255	334.6	9.506e-75	0.5387
chr2:66725070	rs12995572	MEIS1	G>C	1660	25491	333.2	1.979e-74	0.6296
chr23:71628912	rs3012642	AL133500.1	A>G	1295	21429	333.1	2.044e-74	0.5936
chr2:144305674	rs6704689	ARHGAP15	A>G	17085	147224	174.5	7.522e-40	1.126
chr2:144403796	rs13409480	ARHGAP15	A>G	44064	404392	88.66	4.699e-21	1.069
chr2:144428286	rs12691689	ARHGAP15	C>T	26925	243429	82.25	1.198e-19	1.072
chr2:144301488	rs34406675	ARHGAP15	G>A	7074	60282	79.99	3.768e-19	1.124
chr9:136149229	rs505922	ABO	T>C	26668	265225	77.27	1.492e-18	0.9345
chr9:136139265	rs657152	ABO	C>A	28573	283398	76.6	2.097e-18	0.9359
chr9:136142355	rs643434	ABO	G>A	28684	284340	75.19	4.277e-18	0.9365
chr9:136142203	rs514659	ABO	A>C	25894	257240	74.25	6.887e-18	0.9349
chr9:136132908	rs8176719	ABO	T>TC	28601	283682	74.24	6.915e-18	0.9368
chr9:136137065	rs687621	ABO	A>G	26778	265969	73.16	1.199e-17	0.9361
chr9:136143442	rs612169	ABO	A>G	26821	266322	72.56	1.623e-17	0.9365
chr2:56040099	rs10199082	-	T>C	12541	111208	60.62	6.927e-15	1.082
chr10:25815417	rs3923088	GPR158	A>G	41571	383288	58.95	1.619e-14	1.056
chr19:38753625	rs7250689	SPINT2	C>T	43305	400007	58.07	2.523e-14	1.056
chr2:56096892	rs3791679	EFEMP1	A>G	18968	189429	56.19	6.563e-14	0.9375
chr6:98364895	rs9482094	-	G>A	31429	308836	55.15	1.118e-13	0.9465
chr7:102466741	rs1541519	FBXL13	G>T	30473	278966	53.75	2.274e-13	1.056
chr10:25821318	rs10508700	GPR158	T>C	40674	396833	53.19	3.035e-13	0.9494
chr2:144450181	rs1996447	ARHGAP15	T>G	31788	291537	52.48	4.357e-13	1.055
chr19:38735613	rs8102476	SPINT2	C>T	39590	386451	52.05	5.417e-13	0.9498

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr2:144305674	rs6704689	ARHGAP15	A>G	17085	24127	163.5	1.908e-37	1.152
chr10:25815417	rs3923088	GPR158	A>G	41571	63267	76.85	1.847e-18	1.079
chr2:144301488	rs34406675	ARHGAP15	G>A	7074	9878	72.14	2.002e-17	1.148
chr2:144428286	rs12691689	ARHGAP15	C>T	26925	40369	71.7	2.502e-17	1.083
chr2:144403796	rs13409480	ARHGAP15	A>G	44064	67333	69.79	6.601e-17	1.075
chr10:25821318	rs10508700	GPR158	T>C	40674	66857	64.02	1.233e-15	0.9331
chr5:37775861	rs2973069	-	G>A	20668	34716	57.03	4.289e-14	0.9267
chr5:37772780	rs10472291	-	C>A	30047	45514	55.89	7.677e-14	1.071
chr1:234362972	rs10910388	SLC35F3	A>G	11930	17570	44.5	2.548e-11	1.089
chr5:37709829	rs10461984	WDR70	G>A	41360	63615	41.78	1.023e-10	1.058
chr7:102466741	rs1541519	FBXL13	G>T	30473	46462	41.54	1.154e-10	1.06
chr3:15529115	rs4684248	COLQ	T>G	12982	21957	40.82	1.673e-10	0.9261
chr2:144354323	rs67443657	ARHGAP15	C>T	21138	35155	40.78	1.7e-10	0.938
chr11:27748493	rs17309930	-	C>A	17181	28762	39.79	2.825e-10	0.9342
chr2:144450181	rs1996447	ARHGAP15	T>G	31788	48610	39.04	4.146e-10	1.058
chr5:64021531	rs56280150	SREK1IP1	C>T	21005	31700	38.97	4.311e-10	1.066
chr13:107900049	rs11616947	FAM155A	G>A	19631	32686	38.76	4.798e-10	0.9379
chr11:27667202	rs925946	-	G>T	26626	43913	37.74	8.075e-10	0.9442
chr11:27701365	rs10835211	BDNF	G>A	21977	36443	37.66	8.424e-10	0.9411
chr7:102527517	rs10241865	FBXL13	G>A	32310	49486	36.13	1.85e-09	1.055

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: D125	Sigmoid colon	8/20
ICD: K573	Diverticular disease of large intestine without perforation or abscess	17/20
ICD: K579	Diverticular disease of intestine, part unspecified, without perforation or abscess	14/20

ID	Name	Top Correlation
ICD-10: C187	Sigmoid colon	0/20
ICD-10: D127	Rectosigmoid junction	0/20
ICD-10: K571	Diverticular disease of small intestine without perforation or abscess	0/20
ICD-10: K572	Diverticular disease of large intestine with perforation and abscess	0/20
ICD-10: K578	Diverticular disease of intestine, part unspecified, with perforation and abscess	0/20

Colonic diverticula

0002253

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ