Statistics
| Case | Control |
|---|---|
| 616 | 459578 |
Phenotype Definition
An unintentional, oscillating to-and-fro muscle movement affecting head movement. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr9:86337027 | rs7030362 | - | T>C | 87 | 38628 | 25.89 | 3.621e-07 | 1.747 |
| chr16:85892860 | rs17233149 | - | A>C | 243 | 135594 | 25.72 | 3.939e-07 | 1.433 |
| chr11:80861458 | rs59361080 | - | G>A | 69 | 29406 | 23.94 | 9.933e-07 | 1.818 |
| chr12:132365551 | rs73162931 | - | C>A | 60 | 24713 | 23.29 | 1.392e-06 | 1.875 |
| chr5:40477780 | rs6880924 | - | G>T | 341 | 317647 | 22.75 | 1.844e-06 | 0.7407 |
| chr2:12393885 | rs72783930 | - | G>C | 60 | 25423 | 21.8 | 3.032e-06 | 1.838 |
| chr3:30755011 | rs74444822 | - | C>T | 80 | 36565 | 21.52 | 3.494e-06 | 1.699 |
| chr21:17308629 | rs117988969 | - | C>T | 82 | 37751 | 21.44 | 3.648e-06 | 1.687 |
| chr8:128559650 | rs4284014 | - | T>C | 675 | 448403 | 21.08 | 4.403e-06 | 1.292 |
| chr7:139003602 | rs10260850 | - | C>A | 325 | 195690 | 20.99 | 4.614e-06 | 1.341 |
| chr3:61961378 | rs704342 | PTPRG | A>G | 59 | 24967 | 20.89 | 4.872e-06 | 1.823 |
| chr5:79272466 | rs6889652 | - | C>T | 515 | 451089 | 20.74 | 5.274e-06 | 0.7686 |
| chr9:86696174 | rs1968498 | - | T>C | 77 | 35509 | 20.01 | 7.719e-06 | 1.683 |
| chr5:103292556 | rs2195441 | - | A>G | 139 | 148166 | 19.92 | 8.075e-06 | 0.6714 |
| chr1:97099142 | rs11165686 | - | G>A | 402 | 250815 | 19.9 | 8.178e-06 | 1.307 |
| chr7:138916955 | rs58864376 | UBN2 | C>T | 395 | 246121 | 19.47 | 1.02e-05 | 1.305 |
| chr7:128507297 | rs2029623 | KCP | T>C | 30 | 48666 | 19.46 | 1.026e-05 | 0.4519 |
| chr20:45562958 | rs6066127 | EYA2 | T>C | 68 | 30539 | 19.37 | 1.077e-05 | 1.72 |
| chr9:34373041 | rs10972084 | MYORG | C>T | 279 | 165904 | 19.27 | 1.134e-05 | 1.345 |
| chr18:55791003 | rs7231139 | NEDD4L | C>T | 32 | 11346 | 19.27 | 1.136e-05 | 2.155 |
| chr9:86337027 | rs7030362 | - | T>C | 86 | 38021 | 24.91 | 6.012e-07 | 1.736 |
| chr12:132365551 | rs73162931 | - | C>A | 60 | 24355 | 23.56 | 1.208e-06 | 1.883 |
| chr2:12393885 | rs72783930 | - | G>C | 58 | 23833 | 22.45 | 2.154e-06 | 1.874 |
| chr16:85892860 | rs17233149 | - | A>C | 236 | 132406 | 22.35 | 2.266e-06 | 1.406 |
| chr7:138916955 | rs58864376 | UBN2 | C>T | 367 | 222382 | 21.08 | 4.405e-06 | 1.33 |
| chr3:30755011 | rs74444822 | - | C>T | 79 | 35794 | 20.96 | 4.695e-06 | 1.694 |
| chr15:85470292 | rs2122859 | SLC28A1 | G>T | 360 | 218527 | 20.78 | 5.155e-06 | 1.33 |
| chr8:128559650 | rs4284014 | - | T>C | 646 | 423695 | 20.66 | 5.483e-06 | 1.297 |
| chr8:109686625 | rs7844999 | TMEM74 | G>A | 552 | 354774 | 20.64 | 5.531e-06 | 1.297 |
| chr5:144103375 | rs2041070 | - | A>G | 316 | 291619 | 20.42 | 6.207e-06 | 0.7451 |
| chr20:45562958 | rs6066127 | EYA2 | T>C | 66 | 28702 | 20.4 | 6.296e-06 | 1.759 |
| chr3:61961378 | rs704342 | PTPRG | A>G | 58 | 24328 | 20.36 | 6.43e-06 | 1.82 |
| chr21:17308629 | rs117988969 | - | C>T | 78 | 35544 | 20.29 | 6.666e-06 | 1.685 |
| chr11:80861458 | rs59361080 | - | G>A | 62 | 26601 | 20.17 | 7.068e-06 | 1.783 |
| chr2:158695859 | rs35339214 | ACVR1 | G>A | 43 | 16477 | 20.11 | 7.324e-06 | 1.981 |
| chr9:107813550 | rs72740311 | - | T>C | 36 | 13099 | 19.74 | 8.859e-06 | 2.088 |
| chr7:138993919 | rs17160863 | - | A>G | 48 | 19169 | 19.68 | 9.158e-06 | 1.902 |
| chr12:129700697 | rs10773613 | TMEM132D | G>A | 650 | 427448 | 19.59 | 9.596e-06 | 1.287 |
| chr13:61618952 | rs78276390 | - | G>C | 44 | 17065 | 19.46 | 1.028e-05 | 1.947 |
| chr23:9746255 | rs73194156 | GPR143 | C>G | 28 | 9041 | 19.41 | 1.053e-05 | 2.277 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr23:55778139 | rs1007153 | RRAGB | C>T | 298 | 245 | 24.65 | 6.884e-07 | 1.639 |
| chr23:55852696 | rs5914476 | - | T>G | 290 | 241 | 23.85 | 1.041e-06 | 1.633 |
| chr3:173210068 | rs77101745 | NLGN1 | A>G | 109 | 69 | 22.26 | 2.385e-06 | 2.087 |
| chr7:153731451 | rs116066333 | DPP6 | A>T | 107 | 223 | 21.48 | 3.583e-06 | 0.5649 |
| chr10:109373884 | rs12765333 | - | A>G | 112 | 230 | 21.03 | 4.516e-06 | 0.5739 |
| chr3:61961378 | rs704342 | PTPRG | A>G | 58 | 27 | 20.59 | 5.699e-06 | 2.8 |
| chr23:57979353 | rs73226048 | - | T>C | 242 | 197 | 20.37 | 6.381e-06 | 1.622 |
| chr23:57313357 | rs2516023 | FAAH2 | T>C | 250 | 205 | 19.74 | 8.866e-06 | 1.6 |
| chr23:56640134 | rs74503599 | - | C>T | 265 | 221 | 19.53 | 9.921e-06 | 1.579 |
| chr23:57480930 | rs1594503 | FAAH2 | C>T | 269 | 224 | 19.51 | 1.002e-05 | 1.576 |
| chr5:144322230 | rs35778576 | - | C>T | 361 | 576 | 19.12 | 1.229e-05 | 0.6997 |
| chr23:55747717 | rs5913856 | RRAGB | A>G | 269 | 227 | 19.11 | 1.235e-05 | 1.566 |
| chr10:3179842 | rs2306319 | PFKP | C>T | 309 | 505 | 19.04 | 1.283e-05 | 0.6901 |
| chr14:87123014 | rs17122593 | - | C>T | 366 | 582 | 18.96 | 1.335e-05 | 0.7017 |
| chr7:11286221 | rs80105652 | - | A>G | 130 | 94 | 18.7 | 1.533e-05 | 1.828 |
| chr14:38682693 | rs4640088 | - | G>A | 221 | 188 | 18.67 | 1.556e-05 | 1.588 |
| chr23:57129959 | rs5914052 | - | A>G | 245 | 205 | 18.55 | 1.656e-05 | 1.581 |
| chr3:159653368 | rs13084736 | - | C>A | 596 | 625 | 18.5 | 1.695e-05 | 1.393 |
| chr23:57622607 | rs1997715 | ZXDB | G>A | 248 | 207 | 18.38 | 1.812e-05 | 1.573 |
| chr23:55476740 | rs57620007 | - | T>C | 278 | 238 | 18.29 | 1.899e-05 | 1.541 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: G250 | Essential tremor | 3/20 |
| ICD: G431 | Migraine with aura [classical migraine] | 1/20 |
| ID | Name | Top Correlation |
|---|