Abnormality of the immune system


Normal Case/Contol

GWAS of 0002715

Sibling Case/Control

No sibling GWAS available 0002715


Case Control
247196 212998

Phenotype Definition

An abnormality of the immune system. [HPO:probinson]

Phenotype Comment

The immune system is composed of organs and interdependent cell types that collectively protect the body from infections and from the growth of tumor cells. The organs of the immune system comprise the bone marrow, the spleen, the thymus,the lymph nodes, and the cell types comprise B cells, T cells, natural killer cells, granulocytes,dendritic cells, and macrophages.

Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: A048 Other specified bacterial intestinal infections 1/20
ICD: A09 Diarrhoea and gastro-enteritis of presumed infectious origin 1/20
ICD: A099 Gastroenteritis and colitis of unspecified origin 1/20
ICD: B169 Acute hepatitis B without delta-agent and without hepatic coma 1/20
ICD: B181 Chronic viral hepatitis B without delta-agent 2/20
ICD: B182 Chronic viral hepatitis C 1/20
ICD: B980 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters 1/20
ICD: C159 Oesophagus, unspecified 1/20
ICD: C441 Skin of eyelid, including canthus 3/20
ICD: C442 Skin of ear and external auricular canal 3/20
ICD: C443 Skin of other and unspecified parts of face 3/20
ICD: C444 Skin of scalp and neck 3/20
ICD: C446 Skin of upper limb, including shoulder 3/20
ICD: C771 Intrathoracic lymph nodes 1/20
ICD: C911 Chronic lymphocytic leukaemia 2/20
ICD: D24 Benign neoplasm of breast 2/20
ICD: D571 Sickle-cell anaemia without crisis 1/20
ICD: D649 Anaemia, unspecified 1/20
ICD: D70 Agranulocytosis 1/20
ICD: D860 Sarcoidosis of lung 1/20
ICD: D868 Sarcoidosis of other and combined sites 1/20
ICD: D869 Sarcoidosis, unspecified 1/20
ICD: E104 With neurological complications 2/20
ICD: F10 Mental and behavioural disorders due to use of alcohol 4/20
ICD: H405 Glaucoma secondary to other eye disorders 1/20
ICD: H530 Amblyopia ex anopsia 1/20
ICD: H538 Other visual disturbances 1/20
ICD: I319 Disease of pericardium, unspecified 1/20
ICD: J181 Lobar pneumonia, unspecified 1/20
ICD: J22 Unspecified acute lower respiratory infection 1/20
ICD: J301 Allergic rhinitis due to pollen 1/20
ICD: J310 Chronic rhinitis 1/20
ICD: J330 Polyp of nasal cavity 1/20
ICD: J440 Chronic obstructive pulmonary disease with acute lower respiratory infection 1/20
ICD: J441 Chronic obstructive pulmonary disease with acute exacerbation, unspecified 1/20
ICD: K053 Chronic periodontitis 1/20
ICD: K20 Oesophagitis 2/20
ICD: K21 Gastro-oesophageal reflux disease 3/20
ICD: K210 Gastro-oesophageal reflux disease with oesophagitis 1/20
ICD: K221 Ulcer of oesophagus 1/20
ICD: K29 Gastritis and duodenitis 2/20
ICD: K297 Gastritis, unspecified 1/20
ICD: K30 Dyspepsia 1/20
ICD: K513 Ulcerative (chronic) rectosigmoiditis 1/20
ICD: K519 Ulcerative colitis, unspecified 1/20
ICD: K621 Rectal polyp 2/20
ICD: K660 Peritoneal adhesions 2/20
ICD: K801 Calculus of gallbladder with other cholecystitis 3/20
ICD: K802 Calculus of gallbladder without cholecystitis 3/20
ICD: K804 Calculus of bile duct with cholecystitis 2/20
ICD: K805 Calculus of bile duct without cholangitis or cholecystitis 3/20
ICD: K821 Hydrops of gallbladder 2/20
ICD: K838 Other specified diseases of biliary tract 2/20
ICD: K85 Acute pancreatitis 2/20
ICD: L031 Cellulitis of other parts of limb 2/20
ICD: L989 Disorder of skin and subcutaneous tissue, unspecified 2/20
ICD: M059 Seropositive rheumatoid arthritis, unspecified 1/20
ICD: M069 Rheumatoid arthritis, unspecified 1/20
ICD: M329 Systemic lupus erythematosus, unspecified 1/20
ICD: N12 Tubulo-interstitial nephritis, not specified as acute or chronic 1/20
ICD: N736 Female pelvic peritoneal adhesions 1/20
ICD: O034 Incomplete, without complication 1/20
ICD: O039 Complete or unspecified, without complication 1/20
ICD: O420 Premature rupture of membranes, onset of labour within 24 hours 1/20
ICD: O421 Premature rupture of membranes, onset of labour after 24 hours 1/20
ICD: O721 Other immediate postpartum haemorrhage 1/20
ICD: O990 Anaemia complicating pregnancy, childbirth and the puerperium 1/20
ICD: R101 Pain localised to upper abdomen 2/20
ICD: R102 Pelvic and perineal pain 1/20
ICD: R945 Abnormal results of liver function studies 2/20
ICD: Y838 Other surgical procedures 2/20