Recurrent infections

0002719

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
113473	346721

Phenotype Definition

Increased susceptibility to infections. [HPO:probinson, HPO:skoehler]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr2:44066247	Affx-20090007	ABCG8	G>C	17136	46157	202.2	6.877e-46	1.141
chr2:44065090	Affx-20089987	ABCG5	G>A	16468	44624	175.8	4.09e-40	1.133
chr2:44073656	rs41360247	ABCG8	T>C	16669	45292	170.2	6.812e-39	1.13
chr6:396321	rs12203592	IRF4	C>T	50996	150209	53.96	2.042e-13	1.043
chr2:44185713	rs17031779	LRPPRC	T>C	6334	17598	40.34	2.13e-10	1.099
chr2:44788309	rs72790077	CAMKMT	C>G	4529	12393	39.08	4.067e-10	1.116
chr6:421281	rs62389423	-	G>A	41529	122507	38.36	5.895e-10	1.039
chr19:49211969	rs676388	-	C>T	112985	349297	36.08	1.897e-09	0.9721
chr19:49206172	rs516246	FUT2	T>C	119142	367851	34.08	5.29e-09	0.973
chr19:49206417	rs492602	FUT2	G>A	118918	367268	34.0	5.514e-09	0.973
chr19:49206674	rs601338	FUT2	A>G	118789	366771	33.4	7.512e-09	0.9732
chr19:49206462	rs681343	FUT2	T>C	118938	367216	32.6	1.131e-08	0.9735
chr19:49209010	rs503279	FUT2	C>T	112575	347793	32.52	1.178e-08	0.9735
chr1:201860626	rs2250377	SHISA4	G>A	80636	241091	32.03	1.519e-08	1.029
chr19:49206985	rs602662	FUT2	A>G	112541	347671	31.96	1.573e-08	0.9737
chr19:49208865	rs504963	FUT2	A>G	112984	348941	31.89	1.629e-08	0.9738
chr19:49207206	rs485186	FUT2	G>A	112481	347385	31.81	1.704e-08	0.9738
chr19:49228272	rs2287921	RASIP1	C>T	114353	353041	31.03	2.536e-08	0.9742
chr19:49214470	rs281380	-	T>C	85654	265426	30.94	2.661e-08	0.9731
chr1:201869257	rs2820312	LMOD1	G>A	81199	242859	30.56	3.233e-08	1.028
chr2:44066247	Affx-20090007	ABCG8	G>C	16398	44204	201.4	1.036e-45	1.144
chr2:44065090	Affx-20089987	ABCG5	G>A	15670	42438	178.2	1.176e-40	1.138
chr2:44073656	rs41360247	ABCG8	T>C	15691	42599	171.6	3.333e-39	1.135
chr6:396321	rs12203592	IRF4	C>T	50390	148525	62.52	2.633e-15	1.047
chr6:421281	rs62389423	-	G>A	40974	120891	45.66	1.406e-11	1.044
chr2:136594158	rs2236783	LCT	A>G	46679	146989	41.04	1.488e-10	0.9625
chr2:136643555	rs309125	-	C>T	48550	152744	40.33	2.141e-10	0.9633
chr2:44788309	rs72790077	CAMKMT	C>G	4436	12148	40.17	2.326e-10	1.119
chr2:136407479	rs1446585	R3HDM1	A>G	53744	168716	38.93	4.384e-10	0.9652
chr2:44185713	rs17031779	LRPPRC	T>C	5998	16739	37.28	1.022e-09	1.098
chr2:44074431	rs4245791	ABCG8	T>C	72427	225914	34.93	3.413e-09	0.9698
chr4:151206319	rs6817154	LRBA	T>C	72896	218162	34.53	4.203e-09	1.031
chr2:44073881	rs6544713	ABCG8	C>T	71714	223730	34.39	4.501e-09	0.97
chr4:151199080	rs2290846	LRBA	G>A	66152	197710	34.14	5.13e-09	1.032
chr4:151207127	rs3749574	LRBA	C>T	72889	218205	34.07	5.322e-09	1.031
chr19:49211969	rs676388	-	C>T	104449	323794	31.1	2.454e-08	0.9733
chr2:136555659	rs2322659	LCT	C>T	43455	136487	31.01	2.563e-08	0.9664
chr4:151148930	rs28405622	DCLK2	C>T	70091	209744	30.94	2.658e-08	1.03
chr6:26198046	rs4145878	AL031777.2	T>A	104077	322642	30.29	3.715e-08	0.9736
chr19:49206674	rs601338	FUT2	A>G	110119	341000	29.42	5.815e-08	0.9741

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr9:37735123	rs10814614	AL138752.2	A>G	30034	1873	23.13	1.516e-06	1.13
chr4:189977180	rs114977593	-	C>T	2478	236	21.97	2.767e-06	0.7259
chr23:9362962	rs60102760	-	T>G	5388	457	20.66	5.481e-06	0.7983
chr6:68259307	rs34754384	-	A>C	4167	367	19.47	1.02e-05	0.7847
chr20:43343834	rs34077853	CCN5	T>C	16154	976	19.05	1.275e-05	1.16
chr8:5471647	rs117304430	-	C>A	2885	264	18.82	1.433e-05	0.7555
chr11:128902752	rs12804686	ARHGAP32	G>A	8825	722	18.75	1.491e-05	0.8425
chr11:62194412	rs2509957	-	A>C	54965	4047	18.3	1.887e-05	0.9221
chr2:12415960	rs80051594	-	T>C	8423	690	18.28	1.905e-05	0.8412
chr4:55964565	rs3816584	KDR	A>G	53740	3974	18.24	1.947e-05	0.922
chr4:55962545	rs3214870	KDR	T>TG	54546	4024	18.16	2.026e-05	0.9225
chr12:112963146	rs11615234	-	G>A	47963	3553	18.16	2.036e-05	0.9193
chr3:38584845	rs114549077	-	A>G	10584	852	18.14	2.05e-05	0.8558
chr10:129739485	rs79224041	PTPRE	G>A	7009	392	18.04	2.162e-05	1.25
chr15:40360741	rs7181230	-	A>G	78121	5681	18.03	2.179e-05	0.9296
chr17:2778898	rs9898939	RAP1GAP2	T>C	48683	3151	18.03	2.177e-05	1.091
chr15:40380818	rs1540686	BMF	A>G	101381	6762	17.94	2.277e-05	1.073
chr7:36799721	rs12538037	-	T>C	47908	3103	17.77	2.491e-05	1.091
chr9:114690711	rs181289794	UGCG	A>G	4718	406	17.76	2.506e-05	0.8022
chr12:77630237	rs117599658	-	A>G	4459	386	17.69	2.601e-05	0.7982

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: K297	Gastritis, unspecified	1/20
ICD: K801	Calculus of gallbladder with other cholecystitis	3/20
ICD: K802	Calculus of gallbladder without cholecystitis	3/20
ICD: K804	Calculus of bile duct with cholecystitis	3/20
ICD: K805	Calculus of bile duct without cholangitis or cholecystitis	3/20

ID	Name	Top Correlation
ICD-10: A020	Salmonella gastro-enteritis	0/20
ICD-10: A048	Other specified bacterial intestinal infections	0/20
ICD-10: A09	Diarrhoea and gastro-enteritis of presumed infectious origin	0/20
ICD-10: A090	Other and unspecified gastroenteritis and colitis of infectious origin	0/20
ICD-10: A490	Staphylococcal infection, unspecified	0/20
ICD-10: A491	Streptococcal infection, unspecified	0/20
ICD-10: A498	Other bacterial infections of unspecified site	0/20
ICD-10: A499	Bacterial infection, unspecified	0/20
ICD-10: B24	Unspecified human immunodeficiency virus [HIV] disease	0/20
ICD-10: B259	Cytomegaloviral disease, unspecified	0/20
ICD-10: B348	Other viral infections of unspecified site	0/20
ICD-10: B349	Viral infection, unspecified	0/20
ICD-10: B351	Tinea unguium	0/20
ICD-10: B353	Tinea pedis	0/20
ICD-10: B370	Candidal stomatitis	0/20
ICD-10: B373	Candidiasis of vulva and vagina	0/20
ICD-10: B378	Candidiasis of other sites	0/20
ICD-10: B379	Candidiasis, unspecified	0/20
ICD-10: B441	Other pulmonary aspergillosis	0/20
ICD-10: B449	Aspergillosis, unspecified	0/20
ICD-10: B49	Unspecified mycosis	0/20
ICD-10: B961	Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0/20
ICD-10: B964	Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0/20
ICD-10: B980	Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0/20
ICD-10: C099	Tonsil, unspecified	0/20
ICD-10: C169	Stomach, unspecified	0/20
ICD-10: C880	Waldenstrom's macroglobulinaemia	0/20
ICD-10: D801	Nonfamilial hypogammaglobulinaemia	0/20
ICD-10: E892	Postprocedural hypoparathyroidism	0/20
ICD-10: F429	Obsessive-compulsive disorder, unspecified	0/20
ICD-10: G530	Postzoster neuralgia	0/20
ICD-10: G553	Nerve root and plexus compressions in other dorsopathies	0/20
ICD-10: G933	Postviral fatigue syndrome	0/20
ICD-10: H659	Nonsuppurative otitis media, unspecified	0/20
ICD-10: H669	Otitis media, unspecified	0/20
ICD-10: J019	Acute sinusitis, unspecified	0/20
ICD-10: J029	Acute pharyngitis, unspecified	0/20
ICD-10: J039	Acute tonsillitis, unspecified	0/20
ICD-10: J069	Acute upper respiratory infection, unspecified	0/20
ICD-10: J14	Pneumonia due to Haemophilus influenzae	0/20
ICD-10: J150	Pneumonia due to Klebsiella pneumoniae	0/20
ICD-10: J151	Pneumonia due to Pseudomonas	0/20
ICD-10: J152	Pneumonia due to staphylococcus	0/20
ICD-10: J180	Bronchopneumonia, unspecified	0/20
ICD-10: J209	Acute bronchitis, unspecified	0/20
ICD-10: J22	Unspecified acute lower respiratory infection	0/20
ICD-10: J312	Chronic pharyngitis	0/20
ICD-10: J328	Other chronic sinusitis	0/20
ICD-10: J343	Hypertrophy of nasal turbinates	0/20
ICD-10: J350	Chronic tonsillitis	0/20
ICD-10: J36	Peritonsillar abscess	0/20
ICD-10: J398	Other specified diseases of upper respiratory tract	0/20
ICD-10: J40	Bronchitis, not specified as acute or chronic	0/20
ICD-10: J432	Centrilobular emphysema	0/20
ICD-10: J440	Chronic obstructive pulmonary disease with acute lower respiratory infection	0/20
ICD-10: K073	Anomalies of tooth position	0/20
ICD-10: K120	Recurrent oral aphthae	0/20
ICD-10: K293	Chronic superficial gastritis	0/20
ICD-10: K294	Chronic atrophic gastritis	0/20
ICD-10: K295	Chronic gastritis, unspecified	0/20
ICD-10: K296	Other gastritis	0/20
ICD-10: K30	Dyspepsia	0/20
ICD-10: K621	Rectal polyp	0/20
ICD-10: L032	Cellulitis of face	0/20
ICD-10: L088	Other specified local infections of skin and subcutaneous tissue	0/20
ICD-10: L089	Local infection of skin and subcutaneous tissue, unspecified	0/20
ICD-10: L600	Ingrowing nail	0/20
ICD-10: L608	Other nail disorders	0/20
ICD-10: L732	Hidradenitis suppurativa	0/20
ICD-10: L988	Other specified disorders of skin and subcutaneous tissue	0/20
ICD-10: M238	Other internal derangements of knee	0/20
ICD-10: M239	Internal derangement of knee, unspecified	0/20
ICD-10: M500	Cervical disk disorder with myelopathy	0/20
ICD-10: M549	Dorsalgia, unspecified	0/20
ICD-10: M790	Rheumatism, unspecified	0/20
ICD-10: N028	Other	0/20
ICD-10: N059	Unspecified	0/20
ICD-10: N138	Other obstructive and reflux uropathy	0/20
ICD-10: N139	Obstructive and reflux uropathy, unspecified	0/20
ICD-10: N300	Acute cystitis	0/20
ICD-10: N302	Other chronic cystitis	0/20
ICD-10: N308	Other cystitis	0/20
ICD-10: N309	Cystitis, unspecified	0/20
ICD-10: N321	Vesicointestinal fistula	0/20
ICD-10: N368	Other specified disorders of urethra	0/20
ICD-10: N390	Urinary tract infection, site not specified	0/20
ICD-10: N399	Disorder of urinary system, unspecified	0/20
ICD-10: O234	Unspecified infection of urinary tract in pregnancy	0/20
ICD-10: R062	Wheezing	0/20
ICD-10: R070	Pain in throat	0/20
ICD-10: R53	Malaise and fatigue	0/20
ICD-10: R845	Abnormal microbiological findings	0/20
ICD-10: T885	Other complications of anaesthesia	0/20
ICD-10: Y846	Urinary catheterisation	0/20

Recurrent infections

0002719

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ