Functional respiratory abnormality

0002795

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
120168	340026

Phenotype Comment

This category describes not-primarily structural lesions.

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr6:32607376	rs34250758	HLA-DQA1	G>A	51627	138636	125.9	3.204e-29	1.067
chr6:32582650	rs3104413	-	C>G	48612	130457	119.7	7.236e-28	1.067
chr6:32577973	rs532965	-	T>G	49003	131534	117.8	1.943e-27	1.066
chr6:32583357	rs6931277	-	A>T	47979	128713	116.5	3.725e-27	1.066
chr6:32577380	rs660895	-	A>G	55030	148617	104.3	1.721e-24	1.059
chr6:32581973	rs521539	-	G>A	55037	148760	101.0	8.999e-24	1.058
chr6:32303848	rs28361060	TSBP1	G>A	57625	156235	93.41	4.254e-22	1.055
chr6:32282854	rs6910071	TSBP1	A>G	57532	156068	90.51	1.839e-21	1.054
chr6:32387809	rs2395163	-	T>C	57311	155472	89.97	2.418e-21	1.054
chr6:32333341	rs9268362	TSBP1	A>G	57739	156672	89.81	2.627e-21	1.054
chr6:32379295	rs9268515	-	G>C	48730	131640	88.39	5.365e-21	1.057
chr6:32402778	rs9268614	-	T>G	58263	158195	88.25	5.781e-21	1.053
chr6:32257284	rs9268145	TSBP1	T>G	57499	156129	86.4	1.467e-20	1.053
chr6:32625869	Affx-28496566	-	C>T	94423	273539	77.14	1.591e-18	0.9585
chr6:32371915	rs3793127	BTNL2	C>T	57305	156059	73.29	1.122e-17	1.049
chr6:32375973	rs3763309	-	C>A	57215	155866	72.67	1.535e-17	1.048
chr6:32428062	rs9268833	-	C>T	81652	224145	72.62	1.57e-17	1.043
chr6:32620399	rs17843606	-	T>G	96429	279450	71.19	3.238e-17	0.9605
chr6:32428115	rs9268835	-	G>A	81609	224105	70.99	3.592e-17	1.043
chr6:32376348	rs3763312	-	G>A	56886	154989	70.96	3.647e-17	1.048
chr6:32607376	rs34250758	HLA-DQA1	G>A	49819	133471	139.3	3.839e-32	1.072
chr6:32582650	rs3104413	-	C>G	47067	126127	128.8	7.637e-30	1.071
chr6:32577973	rs532965	-	T>G	47451	127216	125.6	3.67e-29	1.07
chr6:32583357	rs6931277	-	A>T	46472	124484	125.0	5.14e-29	1.07
chr6:32577380	rs660895	-	A>G	52788	142179	118.9	1.082e-27	1.065
chr6:32581973	rs521539	-	G>A	52791	142304	115.4	6.359e-27	1.064
chr6:32303848	rs28361060	TSBP1	G>A	56359	152878	95.44	1.523e-22	1.056
chr6:32282854	rs6910071	TSBP1	A>G	56265	152715	92.42	7.025e-22	1.056
chr6:32333341	rs9268362	TSBP1	A>G	56471	153311	91.78	9.689e-22	1.055
chr6:32379295	rs9268515	-	G>C	47597	128589	91.47	1.132e-21	1.059
chr6:32257284	rs9268145	TSBP1	T>G	56228	152767	88.3	5.63e-21	1.054
chr6:32387809	rs2395163	-	T>C	54859	148970	87.5	8.407e-21	1.055
chr6:32402778	rs9268614	-	T>G	55706	151413	85.34	2.518e-20	1.054
chr6:32428062	rs9268833	-	C>T	78032	214083	78.85	6.712e-19	1.046
chr6:32428115	rs9268835	-	G>A	77990	214044	77.24	1.517e-18	1.046
chr6:32371915	rs3793127	BTNL2	C>T	54953	149701	74.02	7.715e-18	1.05
chr6:32375973	rs3763309	-	C>A	54866	149521	73.32	1.101e-17	1.05
chr6:32625869	Affx-28496566	-	C>T	87905	255011	73.31	1.108e-17	0.9583
chr6:32376348	rs3763312	-	G>A	54559	148689	72.18	1.961e-17	1.05
chr6:32620399	rs17843606	-	T>G	89736	260604	69.98	5.982e-17	0.9596

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr6:32607376	rs34250758	HLA-DQA1	G>A	49819	24960	59.28	1.365e-14	1.069
chr6:32582650	rs3104413	-	C>G	47067	23545	57.15	4.04e-14	1.069
chr6:32577973	rs532965	-	T>G	47451	23748	55.5	9.361e-14	1.068
chr6:32583357	rs6931277	-	A>T	46472	23253	53.92	2.091e-13	1.068
chr6:32577380	rs660895	-	A>G	52788	26560	51.27	8.063e-13	1.063
chr6:32581973	rs521539	-	G>A	52791	26583	49.41	2.077e-12	1.061
chr6:32379295	rs9268515	-	G>C	47597	23929	46.48	9.243e-12	1.062
chr6:32303848	rs28361060	TSBP1	G>A	56359	28587	38.59	5.222e-10	1.053
chr6:32387809	rs2395163	-	T>C	54859	27824	37.46	9.337e-10	1.052
chr6:32282854	rs6910071	TSBP1	A>G	56265	28570	36.57	1.469e-09	1.051
chr6:32625869	Affx-28496566	-	C>T	87905	47601	36.41	1.601e-09	0.9571
chr6:32620399	rs17843606	-	T>G	89736	48677	36.38	1.621e-09	0.9576
chr6:32333341	rs9268362	TSBP1	A>G	56471	28680	35.97	2.006e-09	1.051
chr6:32402778	rs9268614	-	T>G	55706	28297	35.52	2.528e-09	1.051
chr6:32257284	rs9268145	TSBP1	T>G	56228	28578	35.35	2.749e-09	1.05
chr6:32376348	rs3763312	-	G>A	54559	27708	34.74	3.768e-09	1.051
chr6:32613712	rs9273215	HLA-DQA1	A>G	92111	49878	34.51	4.249e-09	0.959
chr6:32428062	rs9268833	-	C>T	78032	39958	34.35	4.614e-09	1.045
chr6:32371915	rs3793127	BTNL2	C>T	54953	27917	34.26	4.823e-09	1.05
chr6:32620775	rs17843619	-	A>C	91807	49719	34.2	4.966e-09	0.9592

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: C099	Tonsil, unspecified	3/20
ICD: J22	Unspecified acute lower respiratory infection	10/20
ICD: J330	Polyp of nasal cavity	6/20
ICD: J339	Nasal polyp, unspecified	6/20
ICD: J459	Asthma, unspecified	8/20

ID	Name	Top Correlation
ICD-10: A498	Other bacterial infections of unspecified site	0/20
ICD-10: A499	Bacterial infection, unspecified	0/20
ICD-10: B441	Other pulmonary aspergillosis	0/20
ICD-10: B963	Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0/20
ICD-10: C342	Middle lobe, bronchus or lung	0/20
ICD-10: C343	Lower lobe, bronchus or lung	0/20
ICD-10: C349	Bronchus or lung, unspecified	0/20
ICD-10: C440	Skin of lip	0/20
ICD-10: D140	Middle ear, nasal cavity and accessory sinuses	0/20
ICD-10: D230	Skin of lip	0/20
ICD-10: D24	Benign neoplasm of breast	0/20
ICD-10: E079	Disorder of thyroid, unspecified	0/20
ICD-10: E105	With peripheral circulatory complications	0/20
ICD-10: E115	With peripheral circulatory complications	0/20
ICD-10: E162	Hypoglycaemia, unspecified	0/20
ICD-10: E662	Extreme obesity with alveolar hypoventilation	0/20
ICD-10: E877	Fluid overload	0/20
ICD-10: F410	Panic disorder [episodic paroxysmal anxiety]	0/20
ICD-10: G458	Other transient cerebral ischaemic attacks and related syndromes	0/20
ICD-10: G470	Disorders of initiating and maintaining sleep [insomnias]	0/20
ICD-10: G473	Sleep apnoea	0/20
ICD-10: G478	Other sleep disorders	0/20
ICD-10: G479	Sleep disorder, unspecified	0/20
ICD-10: G500	Trigeminal neuralgia	0/20
ICD-10: G952	Cord compression, unspecified	0/20
ICD-10: G960	Cerebrospinal fluid leak	0/20
ICD-10: H000	Hordeolum and other deep inflammation of eyelid	0/20
ICD-10: H355	Hereditary retinal dystrophy	0/20
ICD-10: H570	Anomalies of pupillary function	0/20
ICD-10: H579	Disorder of eye and adnexa, unspecified	0/20
ICD-10: I080	Disorders of both mitral and aortic valves	0/20
ICD-10: I151	Hypertension secondary to other renal disorders	0/20
ICD-10: I214	Acute subendocardial myocardial infarction	0/20
ICD-10: I269	Pulmonary embolism without mention of acute cor pulmonale	0/20
ICD-10: I270	Primary pulmonary hypertension	0/20
ICD-10: I272	Other secondary pulmonary hypertension	0/20
ICD-10: I279	Pulmonary heart disease, unspecified	0/20
ICD-10: I460	Cardiac arrest with successful resuscitation	0/20
ICD-10: I500	Congestive heart failure	0/20
ICD-10: I501	Left ventricular failure	0/20
ICD-10: I509	Heart failure, unspecified	0/20
ICD-10: I730	Raynaud's syndrome	0/20
ICD-10: I822	Embolism and thrombosis of vena cava	0/20
ICD-10: I878	Other specified disorders of veins	0/20
ICD-10: I99	Other and unspecified disorders of circulatory system	0/20
ICD-10: J00	Acute nasopharyngitis [common cold]	0/20
ICD-10: J040	Acute laryngitis	0/20
ICD-10: J069	Acute upper respiratory infection, unspecified	0/20
ICD-10: J100	Influenza with pneumonia, influenza virus identified	0/20
ICD-10: J13	Pneumonia due to Streptococcus pneumoniae	0/20
ICD-10: J14	Pneumonia due to Haemophilus influenzae	0/20
ICD-10: J189	Pneumonia, unspecified	0/20
ICD-10: J209	Acute bronchitis, unspecified	0/20
ICD-10: J301	Allergic rhinitis due to pollen	0/20
ICD-10: J303	Other allergic rhinitis	0/20
ICD-10: J304	Allergic rhinitis, unspecified	0/20
ICD-10: J320	Chronic maxillary sinusitis	0/20
ICD-10: J324	Chronic pansinusitis	0/20
ICD-10: J351	Hypertrophy of tonsils	0/20
ICD-10: J384	Oedema of larynx	0/20
ICD-10: J387	Other diseases of larynx	0/20
ICD-10: J398	Other specified diseases of upper respiratory tract	0/20
ICD-10: J42	Unspecified chronic bronchitis	0/20
ICD-10: J432	Centrilobular emphysema	0/20
ICD-10: J440	Chronic obstructive pulmonary disease with acute lower respiratory infection	0/20
ICD-10: J441	Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0/20
ICD-10: J448	Other specified chronic obstructive pulmonary disease	0/20
ICD-10: J449	Chronic obstructive pulmonary disease, unspecified	0/20
ICD-10: J450	Predominantly allergic asthma	0/20
ICD-10: J46	Status asthmaticus	0/20
ICD-10: J47	Bronchiectasis	0/20
ICD-10: J61	Pneumoconiosis due to asbestos and other mineral fibres	0/20
ICD-10: J80	Adult respiratory distress syndrome	0/20
ICD-10: J869	Pyothorax without fistula	0/20
ICD-10: J920	Pleural plaque with presence of asbestos	0/20
ICD-10: J929	Pleural plaque without asbestos	0/20
ICD-10: J950	Tracheostomy malfunction	0/20
ICD-10: J958	Other postprocedural respiratory disorders	0/20
ICD-10: J960	Acute respiratory failure	0/20
ICD-10: J961	Chronic respiratory failure	0/20
ICD-10: J969	Respiratory failure, unspecified	0/20
ICD-10: J984	Other disorders of lung	0/20
ICD-10: J988	Other specified respiratory disorders	0/20
ICD-10: J989	Respiratory disorder, unspecified	0/20
ICD-10: K108	Other specified diseases of jaws	0/20
ICD-10: K148	Other diseases of tongue	0/20
ICD-10: K227	Barrett's oesophagus	0/20
ICD-10: K528	Other specified non-infective gastro-enteritis and colitis	0/20
ICD-10: K821	Hydrops of gallbladder	0/20
ICD-10: L089	Local infection of skin and subcutaneous tissue, unspecified	0/20
ICD-10: L89	Decubitus ulcer	0/20
ICD-10: L929	Granulomatous disorder of skin and subcutaneous tissue, unspecified	0/20
ICD-10: L989	Disorder of skin and subcutaneous tissue, unspecified	0/20
ICD-10: M254	Effusion of joint	0/20
ICD-10: N508	Other specified disorders of male genital organs	0/20
ICD-10: N719	Inflammatory disease of uterus, unspecified	0/20
ICD-10: O120	Gestational oedema	0/20
ICD-10: O622	Other uterine inertia	0/20
ICD-10: Q273	Peripheral arteriovenous malformation	0/20
ICD-10: Q892	Congenital malformations of other endocrine glands	0/20
ICD-10: R042	Haemoptysis	0/20
ICD-10: R05	Cough	0/20
ICD-10: R060	Dyspnoea	0/20
ICD-10: R061	Stridor	0/20
ICD-10: R062	Wheezing	0/20
ICD-10: R064	Hyperventilation	0/20
ICD-10: R065	Mouth breathing	0/20
ICD-10: R066	Hiccough	0/20
ICD-10: R068	Other and unspecified abnormalities of breathing	0/20
ICD-10: R070	Pain in throat	0/20
ICD-10: R071	Chest pain on breathing	0/20
ICD-10: R090	Asphyxia	0/20
ICD-10: R091	Pleurisy	0/20
ICD-10: R092	Respiratory arrest	0/20
ICD-10: R093	Abnormal sputum	0/20
ICD-10: R098	Other specified symptoms and signs involving the circulatory and respiratory systems	0/20
ICD-10: R42	Dizziness and giddiness	0/20
ICD-10: R500	Fever with chills	0/20
ICD-10: R688	Other specified general symptoms and signs	0/20
ICD-10: R69	Unknown and unspecified causes of morbidity	0/20
ICD-10: R700	Elevated erythrocyte sedimentation rate	0/20
ICD-10: R739	Hyperglycaemia, unspecified	0/20
ICD-10: R778	Other specified abnormalities of plasma proteins	0/20
ICD-10: T179	Foreign body in respiratory tract, part unspecified	0/20
ICD-10: T181	Foreign body in oesophagus	0/20
ICD-10: T393	Other nonsteroidal anti-inflammatory drugs [NSAID]	0/20
ICD-10: T598	Other specified gases, fumes and vapours	0/20
ICD-10: T884	Failed or difficult intubation	0/20
ICD-10: X600	Home	0/20
ICD-10: Y433	Other antineoplastic drugs	0/20
ICD-10: Y86	Sequelae of other accidents	0/20

Functional respiratory abnormality

0002795

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Comment

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ