Statistics
| Case | Control |
|---|---|
| 3621 | 456573 |
Phenotype Definition
An increased excretion of phosphates in the urine. [HPO:curators]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr8:145639681 | rs1871534 | SLC39A4 | G>C | 248 | 17897 | 73.44 | 1.035e-17 | 1.733 |
| chr17:58508582 | rs8071181 | C17orf64 | G>A | 214 | 15203 | 67.24 | 2.409e-16 | 1.759 |
| chr23:64367019 | rs7064929 | - | G>A | 240 | 17326 | 66.25 | 3.974e-16 | 1.704 |
| chr23:53347028 | rs1547218 | IQSEC2 | T>C | 462 | 38791 | 65.2 | 6.753e-16 | 1.478 |
| chr23:106146349 | rs5962774 | MORC4 | T>C | 165 | 10861 | 63.31 | 1.768e-15 | 1.864 |
| chr17:58506748 | rs57928695 | C17orf64 | C>T | 149 | 9698 | 62.89 | 2.181e-15 | 1.915 |
| chr1:159174683 | rs2814778 | ACKR1 | T>C | 253 | 19124 | 62.84 | 2.245e-15 | 1.656 |
| chr18:9536315 | rs14336 | RALBP1 | A>C | 183 | 12684 | 62.57 | 2.573e-15 | 1.799 |
| chr10:117649124 | rs7904803 | ATRNL1 | C>A | 243 | 18443 | 59.78 | 1.062e-14 | 1.653 |
| chr15:45694768 | rs1834686 | SPATA5L1 | G>T | 151 | 10068 | 58.91 | 1.652e-14 | 1.869 |
| chr9:129979758 | rs3780318 | RALGPS1 | G>A | 217 | 16024 | 58.86 | 1.696e-14 | 1.692 |
| chr12:132549300 | rs7136109 | EP400 | A>G | 155 | 10475 | 57.8 | 2.895e-14 | 1.844 |
| chr15:45556163 | rs8023604 | SLC28A2 | T>C | 180 | 12731 | 57.33 | 3.687e-14 | 1.764 |
| chr9:129984107 | rs3739553 | RALGPS1 | G>A | 206 | 15207 | 55.8 | 8.011e-14 | 1.69 |
| chr15:45695612 | rs1346265 | SPATA5L1 | C>T | 165 | 11505 | 55.23 | 1.073e-13 | 1.787 |
| chr3:188327555 | rs7645635 | LPP | T>C | 194 | 14182 | 54.7 | 1.406e-13 | 1.707 |
| chr17:29298304 | rs7225888 | RNF135 | C>G | 252 | 19683 | 54.32 | 1.705e-13 | 1.601 |
| chr4:178655568 | rs4428236 | - | T>C | 159 | 11070 | 53.7 | 2.337e-13 | 1.792 |
| chr4:110940045 | rs4698804 | - | T>C | 234 | 18030 | 53.34 | 2.803e-13 | 1.621 |
| chr17:29290106 | rs55861543 | - | C>T | 259 | 20500 | 52.64 | 4.001e-13 | 1.58 |
| chr1:46869415 | rs115770031 | FAAH | A>G | 235 | 21467 | 24.48 | 7.491e-07 | 1.389 |
| chr12:10909412 | rs7316817 | - | A>G | 721 | 107576 | 22.93 | 1.678e-06 | 0.8283 |
| chr12:62781002 | rs11174454 | USP15 | A>G | 674 | 71289 | 22.61 | 1.986e-06 | 1.213 |
| chr1:93639101 | rs10874762 | TMED5 | G>T | 2718 | 319397 | 21.12 | 4.325e-06 | 1.118 |
| chr19:53300454 | rs6509685 | - | C>A | 774 | 83323 | 21.1 | 4.36e-06 | 1.192 |
| chr5:142555241 | rs72799993 | ARHGAP26 | T>C | 173 | 15464 | 20.7 | 5.385e-06 | 1.419 |
| chr19:53300984 | rs9917029 | ZNF28 | T>C | 771 | 83267 | 20.51 | 5.923e-06 | 1.189 |
| chr11:36480683 | rs9630172 | PRR5L | G>A | 468 | 48173 | 20.28 | 6.706e-06 | 1.241 |
| chr9:129571638 | rs1329407 | ZBTB43 | G>T | 1829 | 210245 | 20.08 | 7.425e-06 | 1.129 |
| chr4:27897657 | rs75600365 | - | G>T | 937 | 135396 | 19.96 | 7.898e-06 | 0.8548 |
| chr19:53307415 | rs7256471 | ZNF28 | G>T | 1002 | 110771 | 19.59 | 9.602e-06 | 1.163 |
| chr10:125058869 | rs4980184 | - | T>C | 34 | 8946 | 19.37 | 1.078e-05 | 0.4767 |
| chr3:5609942 | rs115356514 | - | C>A | 202 | 18800 | 19.09 | 1.249e-05 | 1.366 |
| chr14:74595745 | rs77145678 | LIN52 | G>T | 219 | 20679 | 18.67 | 1.554e-05 | 1.346 |
| chr11:10378219 | rs2957710 | AMPD3 | A>G | 562 | 59399 | 18.6 | 1.611e-05 | 1.209 |
| chr3:5689828 | rs9311600 | - | C>T | 204 | 19066 | 18.56 | 1.647e-05 | 1.359 |
| chr23:9360426 | rs6530275 | - | C>T | 1892 | 215855 | 18.49 | 1.706e-05 | 1.129 |
| chr23:9387424 | rs5933734 | - | A>G | 1661 | 188078 | 18.16 | 2.03e-05 | 1.133 |
| chr21:33685280 | rs2236611 | MRAP | T>C | 2015 | 234313 | 18.14 | 2.049e-05 | 1.119 |
| chr1:110109039 | rs518076 | GNAI3 | A>G | 657 | 97021 | 18.13 | 2.058e-05 | 0.8398 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr2:46017051 | rs76114421 | PRKCE | C>T | 110 | 10 | 46.22 | 1.056e-11 | 0.1335 |
| chr6:24010781 | rs71555119 | - | A>G | 73 | 7 | 35.5 | 2.55e-09 | 0.127 |
| chr7:112680155 | rs7803252 | - | A>G | 340 | 17 | 34.55 | 4.145e-09 | 0.2294 |
| chr16:26942861 | rs117671697 | - | C>T | 144 | 10 | 32.65 | 1.103e-08 | 0.1749 |
| chr23:136537766 | rs137982365 | - | G>A | 173 | 10 | 32.42 | 1.244e-08 | 0.1698 |
| chr5:141891596 | rs114536166 | - | G>A | 79 | 7 | 31.04 | 2.531e-08 | 0.1415 |
| chr11:124982148 | rs73012301 | - | A>G | 155 | 10 | 30.16 | 3.986e-08 | 0.1851 |
| chr4:118068675 | rs76515850 | - | G>T | 83 | 7 | 29.49 | 5.612e-08 | 0.1476 |
| chr12:13618558 | rs73059129 | GRIN2B | T>C | 158 | 10 | 28.72 | 8.359e-08 | 0.1918 |
| chr9:86848701 | rs11140463 | - | C>G | 47 | 5 | 28.69 | 8.513e-08 | 0.1165 |
| chr3:123811283 | rs115261913 | KALRN | C>T | 85 | 7 | 28.56 | 9.097e-08 | 0.1513 |
| chr1:156273798 | rs72710215 | - | C>A | 159 | 10 | 28.45 | 9.627e-08 | 0.1931 |
| chr3:43800011 | rs6441794 | - | A>C | 348 | 16 | 28.19 | 1.099e-07 | 0.2528 |
| chr17:631380 | rs78125504 | - | C>T | 66 | 6 | 27.77 | 1.364e-07 | 0.138 |
| chr15:68609647 | rs2271725 | ITGA11 | G>T | 135 | 9 | 27.75 | 1.382e-07 | 0.1838 |
| chr1:156314497 | rs41265043 | CCT3 | C>T | 162 | 10 | 27.68 | 1.43e-07 | 0.1968 |
| chr1:156137537 | rs77531750 | SEMA4A | C>T | 162 | 10 | 27.67 | 1.439e-07 | 0.1969 |
| chr9:113759294 | rs78679577 | LPAR1 | G>A | 68 | 6 | 26.76 | 2.303e-07 | 0.1422 |
| chr17:50214934 | rs62070289 | CA10 | T>C | 116 | 8 | 25.43 | 4.583e-07 | 0.1808 |
| chr13:35426699 | rs117509955 | - | G>T | 144 | 9 | 25.25 | 5.045e-07 | 0.1965 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: M5494 | Dorsalgia, unspecified (Thoracic region) | 0/20 |
| ICD-10: R81 | Glycosuria | 0/20 |