Bowel diverticulosis

0005222

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

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Sex Split

Interactive Plot

Statistics

Case	Control
44213	415981

Phenotype Definition

The presence of multiple diverticula of the intestine. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	4329	62729	718.3	3.067e-158	0.6513
chr15:48426484	rs1426654	SLC24A5	A>G	1330	26196	686.2	3.046e-151	0.4838
chr5:33958959	rs28777	SLC45A2	A>C	3634	53358	636.6	1.798e-140	0.6451
chr15:48392165	rs1834640	-	A>G	1695	29929	617.5	2.664e-136	0.5396
chr5:33955673	rs35391	SLC45A2	C>T	2652	38328	421.6	1.073e-93	0.6599
chr5:33955326	rs35390	SLC45A2	A>C	2666	38481	421.1	1.41e-93	0.6607
chr5:33951116	rs35397	SLC45A2	T>G	6730	83378	420.9	1.553e-93	0.7636
chr1:159174683	rs2814778	ACKR1	T>C	1031	18346	380.7	8.709e-85	0.5388
chr9:129557967	rs7863211	-	G>A	1023	18179	376.2	8.53e-84	0.5395
chr6:3185712	rs7754077	-	C>T	986	17686	374.3	2.22e-83	0.5345
chr16:28995057	rs11859822	SPNS1	T>C	1813	27623	367.3	7.175e-82	0.6279
chr19:42393286	rs717225	ARHGEF1	A>G	1246	20697	359.2	4.182e-80	0.577
chr2:171380643	rs34020565	MYO3B	T>G	1481	23378	348.5	8.827e-78	0.6069
chr5:147671850	rs7724380	-	G>A	1133	19050	341.6	2.918e-76	0.5703
chr23:128718936	rs2362937	OCRL	T>C	1098	18853	338.2	1.558e-75	0.5666
chr16:28954860	rs7203982	-	T>C	1850	27532	336.1	4.624e-75	0.6431
chr15:45491394	rs1648299	SHF	T>C	916	16243	333.5	1.627e-74	0.5412
chr19:42392441	rs16975619	ARHGEF1	T>C	1130	18880	332.5	2.752e-74	0.5741
chr2:66725070	rs12995572	MEIS1	G>C	1681	25470	330.9	6.248e-74	0.6322
chr23:71628912	rs3012642	AL133500.1	A>G	1319	21405	325.5	9.236e-73	0.5996
chr2:144305674	rs6704689	ARHGAP15	A>G	17211	147098	173.3	1.411e-39	1.125
chr2:144403796	rs13409480	ARHGAP15	A>G	44414	404042	88.8	4.362e-21	1.069
chr2:144428286	rs12691689	ARHGAP15	C>T	27113	243241	78.89	6.563e-19	1.071
chr2:144301488	rs34406675	ARHGAP15	G>A	7119	60237	77.8	1.143e-18	1.122
chr9:136149229	rs505922	ABO	T>C	26901	264992	75.56	3.538e-18	0.9354
chr9:136139265	rs657152	ABO	C>A	28823	283148	74.59	5.801e-18	0.9369
chr9:136142355	rs643434	ABO	G>A	28938	284086	72.86	1.394e-17	0.9377
chr9:136132908	rs8176719	ABO	T>TC	28850	283433	72.43	1.73e-17	0.9377
chr9:136142203	rs514659	ABO	A>C	26122	257012	72.39	1.764e-17	0.9359
chr9:136137065	rs687621	ABO	A>G	27015	265732	71.07	3.452e-17	0.9373
chr9:136143442	rs612169	ABO	A>G	27059	266084	70.38	4.89e-17	0.9377
chr2:56040099	rs10199082	-	T>C	12643	111106	61.3	4.891e-15	1.083
chr2:56096892	rs3791679	EFEMP1	A>G	19096	189301	59.97	9.648e-15	0.9357
chr10:25815417	rs3923088	GPR158	A>G	41902	382957	59.0	1.576e-14	1.056
chr19:38753625	rs7250689	SPINT2	C>T	43652	399660	58.5	2.028e-14	1.056
chr10:25821318	rs10508700	GPR158	T>C	40998	396509	54.11	1.899e-13	0.9491
chr7:102466741	rs1541519	FBXL13	G>T	30716	278723	53.91	2.102e-13	1.056
chr6:98364895	rs9482094	-	G>A	31706	308559	53.14	3.108e-13	0.9476
chr19:38735613	rs8102476	SPINT2	C>T	39907	386134	52.63	4.021e-13	0.9497
chr2:56111309	rs3791675	EFEMP1	C>T	19826	195580	52.41	4.494e-13	0.9405

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr2:144305674	rs6704689	ARHGAP15	A>G	17211	38817	163.5	1.991e-37	1.139
chr2:144301488	rs34406675	ARHGAP15	G>A	7119	15815	77.96	1.052e-18	1.14
chr2:144403796	rs13409480	ARHGAP15	A>G	44414	107562	73.41	1.051e-17	1.071
chr2:144428286	rs12691689	ARHGAP15	C>T	27113	64670	67.92	1.699e-16	1.074
chr10:25815417	rs3923088	GPR158	A>G	41902	101459	66.13	4.223e-16	1.067
chr5:37775861	rs2973069	-	G>A	20853	55259	61.14	5.313e-15	0.9297
chr5:37772780	rs10472291	-	C>A	30280	72661	60.97	5.799e-15	1.068
chr10:25821318	rs10508700	GPR158	T>C	40998	106177	59.91	9.91e-15	0.9401
chr5:37709829	rs10461984	WDR70	G>A	41686	101192	56.86	4.678e-14	1.062
chr1:234362972	rs10910388	SLC35F3	A>G	12020	28079	48.62	3.114e-12	1.085
chr19:38753625	rs7250689	SPINT2	C>T	43652	106452	47.45	5.648e-12	1.056
chr2:56096892	rs3791679	EFEMP1	A>G	19096	50327	43.4	4.454e-11	0.9386
chr13:107900049	rs11616947	FAM155A	G>A	19780	51994	42.19	8.302e-11	0.94
chr3:15529115	rs4684248	COLQ	T>G	13089	34857	41.25	1.339e-10	0.931
chr19:38735613	rs8102476	SPINT2	C>T	39907	102852	41.08	1.464e-10	0.9501
chr11:27748493	rs17309930	-	C>A	17321	45690	40.42	2.048e-10	0.9386
chr2:144450181	rs1996447	ARHGAP15	T>G	32012	77590	40.18	2.317e-10	1.054
chr13:108212612	rs11843418	FAM155A	A>G	16914	44598	39.31	3.609e-10	0.9389
chr9:136139265	rs657152	ABO	C>A	28823	74834	38.56	5.313e-10	0.9488
chr6:32387809	rs2395163	-	T>C	20257	48515	38.52	5.419e-10	1.061

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: D125	Sigmoid colon	8/20
ICD: K573	Diverticular disease of large intestine without perforation or abscess	17/20
ICD: K579	Diverticular disease of intestine, part unspecified, without perforation or abscess	14/20

ID	Name	Top Correlation
ICD-10: C187	Sigmoid colon	0/20
ICD-10: D127	Rectosigmoid junction	0/20
ICD-10: K571	Diverticular disease of small intestine without perforation or abscess	0/20
ICD-10: K572	Diverticular disease of large intestine with perforation and abscess	0/20
ICD-10: K578	Diverticular disease of intestine, part unspecified, with perforation and abscess	0/20
ICD-10: R100	Acute abdomen	0/20

Bowel diverticulosis

0005222

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ