0005293

Case	Control
13807	446387

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr15:48426484	rs1426654	SLC24A5	A>G	430	27096	188.7	6.26e-43	0.5165
chr1:10833232	rs58064215	CASZ1	G>C	9721	287509	161.4	5.65e-37	1.175
chr15:48392165	rs1834640	-	A>G	560	31064	157.0	5.064e-36	0.5866
chr8:145639681	rs1871534	SLC39A4	G>C	265	17880	142.0	9.487e-33	0.4843
chr1:159174683	rs2814778	ACKR1	T>C	307	19070	127.5	1.417e-29	0.5261
chr16:88808743	Affx-13429237	PIEZO1	G>A	4253	119323	125.1	4.812e-29	1.208
chr9:140957557	rs11137360	CACNA1B	A>G	348	20658	124.3	7.24e-29	0.5502
chr5:33951693	rs16891982	SLC45A2	G>C	1504	65554	123.0	1.368e-28	0.7437
chr8:10557760	rs57041981	RP1L1	A>G	250	16398	123.0	1.369e-28	0.4986
chr17:58508582	rs8071181	C17orf64	G>A	223	15194	122.8	1.554e-28	0.48
chr19:42393286	rs717225	ARHGEF1	A>G	373	21570	121.1	3.649e-28	0.5651
chr5:147666044	rs7707813	-	T>C	300	18463	120.8	4.234e-28	0.5312
chr5:147671850	rs7724380	-	G>A	338	19845	115.8	5.258e-27	0.5568
chr9:129979758	rs3780318	RALGPS1	G>A	248	15993	115.7	5.495e-27	0.5075
chr16:88744470	rs8048897	SNAI3	G>T	3009	82104	115.2	7.133e-27	1.234
chr17:29290106	rs55861543	-	C>T	353	20406	114.4	1.067e-26	0.5655
chr9:137925543	rs7027926	-	G>A	264	16556	112.8	2.328e-26	0.5217
chr17:29298304	rs7225888	RNF135	C>G	336	19599	112.5	2.721e-26	0.5604
chr23:71628912	rs3012642	AL133500.1	A>G	439	22285	112.4	2.953e-26	0.6003
chr16:88853729	Affx-13430005	-	T>C	13576	418388	111.6	4.452e-26	1.135
chr1:10833232	rs58064215	CASZ1	G>C	9124	255499	254.5	2.76e-57	1.23
chr1:10831218	rs172228	CASZ1	G>C	4905	133119	170.8	4.926e-39	1.233
chr1:10824329	rs6540950	CASZ1	C>T	5601	157096	134.3	4.657e-31	1.193
chr16:88808743	Affx-13429237	PIEZO1	G>A	4127	113747	117.2	2.617e-27	1.204
chr2:68435280	rs7572554	AC017083.3	T>C	8623	306774	115.3	6.829e-27	0.8681
chr16:88853729	Affx-13430005	-	T>C	13104	394743	114.9	8.157e-27	1.14
chr2:68457573	rs12468533	AC017083.3	T>C	8640	307003	114.1	1.218e-26	0.8688
chr16:88776297	rs4390574	CTU2	C>T	3522	95814	113.9	1.35e-26	1.216
chr2:68385097	rs2044693	AC017083.3	G>A	8987	318062	111.6	4.356e-26	0.8714
chr16:88783521	Affx-13428745	PIEZO1	C>T	3408	92715	110.6	7.187e-26	1.216
chr16:88792047	Affx-13428879	PIEZO1	G>A	3809	104839	108.6	1.977e-25	1.203
chr16:88807896	rs7404939	PIEZO1	G>A	3851	106121	107.4	3.628e-25	1.201
chr16:88804734	rs7184427	PIEZO1	G>A	4650	130145	107.3	3.816e-25	1.186
chr16:88744470	rs8048897	SNAI3	G>T	2924	78520	106.8	4.818e-25	1.228
chr16:88787704	rs8043924	PIEZO1	C>G	3894	107780	103.5	2.655e-24	1.196
chr16:88783449	rs8057031	PIEZO1	G>C	13037	394397	100.3	1.335e-23	1.13
chr2:68409037	rs1868402	AC017083.3	A>G	7202	257177	94.69	2.232e-22	0.8735
chr16:88844433	rs2968482	PIEZO1	T>C	7518	265967	83.97	5.023e-20	0.8819
chr16:88846552	rs62048221	PIEZO1	C>T	5725	205699	81.46	1.784e-19	0.873
chr16:88847523	rs57374020	PIEZO1	T>C	5882	210519	77.27	1.491e-18	0.8771

Location

SNP

Gene

Ref>Alt

Alt in Case

Alt in Control

Chi-square

P-value

Odds ratio

chr15:48426484

rs1426654

SLC24A5

A>G

430

27096

188.7

6.26e-43

0.5165

chr1:10833232

rs58064215

CASZ1

G>C

9721

287509

161.4

5.65e-37

1.175

chr15:48392165

rs1834640

-

A>G

560

31064

157.0

5.064e-36

0.5866

chr8:145639681

rs1871534

SLC39A4

G>C

265

17880

142.0

9.487e-33

0.4843

chr1:159174683

rs2814778

ACKR1

T>C

307

19070

127.5

1.417e-29

0.5261

chr16:88808743

Affx-13429237

PIEZO1

G>A

4253

119323

125.1

4.812e-29

1.208

chr9:140957557

rs11137360

CACNA1B

A>G

348

20658

124.3

7.24e-29

0.5502

chr5:33951693

rs16891982

SLC45A2

G>C

1504

65554

123.0

1.368e-28

0.7437

chr8:10557760

rs57041981

RP1L1

A>G

250

16398

123.0

1.369e-28

0.4986

chr17:58508582

rs8071181

C17orf64

G>A

223

15194

122.8

1.554e-28

0.48

chr19:42393286

rs717225

ARHGEF1

A>G

373

21570

121.1

3.649e-28

0.5651

chr5:147666044

rs7707813

-

T>C

300

18463

120.8

4.234e-28

0.5312

chr5:147671850

rs7724380

-

G>A

338

19845

115.8

5.258e-27

0.5568

chr9:129979758

rs3780318

RALGPS1

G>A

248

15993

115.7

5.495e-27

0.5075

chr16:88744470

rs8048897

SNAI3

G>T

3009

82104

115.2

7.133e-27

1.234

chr17:29290106

rs55861543

-

C>T

353

20406

114.4

1.067e-26

0.5655

chr9:137925543

rs7027926

-

G>A

264

16556

112.8

2.328e-26

0.5217

chr17:29298304

rs7225888

RNF135

C>G

336

19599

112.5

2.721e-26

0.5604

chr23:71628912

rs3012642

AL133500.1

A>G

439

22285

112.4

2.953e-26

0.6003

chr16:88853729

Affx-13430005

-

T>C

13576

418388

111.6

4.452e-26

1.135

chr1:10833232

rs58064215

CASZ1

G>C

9124

255499

254.5

2.76e-57

1.23

chr1:10831218

rs172228

CASZ1

G>C

4905

133119

170.8

4.926e-39

1.233

chr1:10824329

rs6540950

CASZ1

C>T

5601

157096

134.3

4.657e-31

1.193

chr16:88808743

Affx-13429237

PIEZO1

G>A

4127

113747

117.2

2.617e-27

1.204

chr2:68435280

rs7572554

AC017083.3

T>C

8623

306774

115.3

6.829e-27

0.8681

chr16:88853729

Affx-13430005

-

T>C

13104

394743

114.9

8.157e-27

1.14

chr2:68457573

rs12468533

AC017083.3

T>C

8640

307003

114.1

1.218e-26

0.8688

chr16:88776297

rs4390574

CTU2

C>T

3522

95814

113.9

1.35e-26

1.216

chr2:68385097

rs2044693

AC017083.3

G>A

8987

318062

111.6

4.356e-26

0.8714

chr16:88783521

Affx-13428745

PIEZO1

C>T

3408

92715

110.6

7.187e-26

1.216

chr16:88792047

Affx-13428879

PIEZO1

G>A

3809

104839

108.6

1.977e-25

1.203

chr16:88807896

rs7404939

PIEZO1

G>A

3851

106121

107.4

3.628e-25

1.201

chr16:88804734

rs7184427

PIEZO1

G>A

4650

130145

107.3

3.816e-25

1.186

chr16:88744470

rs8048897

SNAI3

G>T

2924

78520

106.8

4.818e-25

1.228

chr16:88787704

rs8043924

PIEZO1

C>G

3894

107780

103.5

2.655e-24

1.196

chr16:88783449

rs8057031

PIEZO1

G>C

13037

394397

100.3

1.335e-23

1.13

chr2:68409037

rs1868402

AC017083.3

A>G

7202

257177

94.69

2.232e-22

0.8735

chr16:88844433

rs2968482

PIEZO1

T>C

7518

265967

83.97

5.023e-20

0.8819

chr16:88846552

rs62048221

PIEZO1

C>T

5725

205699

81.46

1.784e-19

0.873

chr16:88847523

rs57374020

PIEZO1

T>C

5882

210519

77.27

1.491e-18

0.8771

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	1504	1237	135.9	2.125e-31	0.6312
chr15:48426484	rs1426654	SLC24A5	A>G	430	482	132.5	1.151e-30	0.4698
chr9:129979758	rs3780318	RALGPS1	G>A	248	321	117.9	1.803e-27	0.4084
chr1:159174683	rs2814778	ACKR1	T>C	307	368	116.8	3.25e-27	0.4403
chr9:129984107	rs3739553	RALGPS1	G>A	241	311	113.7	1.494e-26	0.4095
chr5:33958959	rs28777	SLC45A2	A>C	1291	1058	113.1	2.005e-26	0.6368
chr23:106146349	rs5962774	MORC4	T>C	168	234	110.8	6.615e-26	0.3581
chr2:66725070	rs12995572	MEIS1	G>C	522	525	110.1	9.169e-26	0.5237
chr17:29290106	rs55861543	-	C>T	353	395	107.9	2.766e-25	0.4717
chr9:117110112	Affx-52344420	AKNA	T>TG	226	293	107.7	3.205e-25	0.4084
chr23:64367019	rs7064929	-	G>A	329	357	106.5	5.685e-25	0.459
chr10:49805216	rs11101394	ARHGAP22	C>T	308	356	104.0	2.004e-24	0.4578
chr5:147666044	rs7707813	-	T>C	300	348	102.8	3.757e-24	0.4558
chr10:79785825	rs3758464	POLR3A	T>G	170	240	102.2	5.014e-24	0.3753
chr16:28995057	rs11859822	SPNS1	T>C	587	561	102.1	5.408e-24	0.5504
chr16:28954860	rs7203982	-	T>C	594	565	101.2	8.304e-24	0.5532
chr2:171380643	rs34020565	MYO3B	T>G	482	484	100.9	9.822e-24	0.5253
chr17:58508582	rs8071181	C17orf64	G>A	223	283	100.3	1.307e-23	0.4167
chr23:128718936	rs2362937	OCRL	T>C	388	393	100.1	1.428e-23	0.4911
chr2:185043361	rs1997132	-	T>C	156	225	99.31	2.156e-23	0.3672
chr1:10833232	rs58064215	CASZ1	G>C	9124	4020	100.9	9.92e-24	1.255
chr16:88853729	Affx-13430005	-	T>C	13104	6139	73.23	1.153e-17	1.195
chr2:68435280	rs7572554	AC017083.3	T>C	8623	4997	62.97	2.099e-15	0.8409
chr2:68457573	rs12468533	AC017083.3	T>C	8640	5001	62.75	2.343e-15	0.8412
chr2:68385097	rs2044693	AC017083.3	G>A	8987	5173	60.73	6.537e-15	0.8448
chr1:10824329	rs6540950	CASZ1	C>T	5601	2445	58.93	1.637e-14	1.228
chr1:10831218	rs172228	CASZ1	G>C	4905	2113	57.36	3.63e-14	1.239
chr16:88804734	rs7184427	PIEZO1	G>A	4650	2031	45.67	1.399e-11	1.216
chr16:88808743	Affx-13429237	PIEZO1	G>A	4127	1800	41.06	1.475e-10	1.214
chr12:48194957	rs2544029	HDAC7	C>T	7954	3688	39.25	3.726e-10	1.157
chr6:29975047	rs356968	-	G>T	7649	4360	39.14	3.936e-10	0.8681
chr2:68409037	rs1868402	AC017083.3	A>G	7202	4126	38.91	4.441e-10	0.8663
chr16:88846552	rs62048221	PIEZO1	C>T	5725	3329	38.86	4.55e-10	0.8571
chr6:30028831	rs1150742	ZNRD1	T>C	7683	4374	38.78	4.737e-10	0.8688
chr12:48195451	rs2544030	HDAC7	G>A	7956	3693	38.77	4.777e-10	1.156
chr5:127347013	rs34145453	-	A>G	10791	5122	38.52	5.412e-10	1.142
chr6:30038352	rs1245371	RNF39	A>G	7662	4359	38.34	5.936e-10	0.8693
chr6:30011934	rs259940	-	A>G	7643	4354	38.24	6.244e-10	0.8695
chr16:88744470	rs8048897	SNAI3	G>T	2924	1237	37.93	7.327e-10	1.245
chr6:29973910	rs356967	-	G>A	7669	4358	37.86	7.586e-10	0.8701

ID	Name	Top Correlation
ICD-10: I830	Varicose veins of lower extremities with ulcer	0/20
ICD-10: I831	Varicose veins of lower extremities with inflammation	0/20
ICD-10: I832	Varicose veins of lower extremities with both ulcer and inflammation	0/20
ICD-10: I872	Venous insufficiency (chronic) (peripheral)	0/20
ICD-10: I878	Other specified disorders of veins	0/20

Venous insufficiency

0005293

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Statistics

Top SNP Information

Associated Diseases ^ⓘ

Venous insufficiency

0005293

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ