Statistics
| Case | Control |
|---|---|
| 822 | 459372 |
Phenotype Definition
Inspiratory stridor is a high pitched sound upon inspiration that is generally related to laryngeal abnormalities. [HPO:curators]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr10:130551159 | rs7094502 | - | A>G | 79 | 23986 | 29.73 | 4.954e-08 | 1.857 |
| chr19:34120344 | rs10401489 | CHST8 | T>G | 69 | 20231 | 28.79 | 8.074e-08 | 1.913 |
| chr12:55391259 | rs880982 | - | A>G | 70 | 20824 | 27.99 | 1.221e-07 | 1.888 |
| chr20:8791797 | rs56131684 | PLCB1 | T>C | 58 | 16379 | 27.18 | 1.857e-07 | 1.981 |
| chr16:11784965 | rs3743584 | TXNDC11 | C>T | 71 | 21427 | 26.98 | 2.054e-07 | 1.859 |
| chr4:6619004 | rs4234764 | MAN2B2 | G>A | 62 | 18036 | 26.44 | 2.719e-07 | 1.924 |
| chr9:107700958 | rs2487036 | - | A>G | 265 | 191696 | 24.92 | 5.989e-07 | 0.7176 |
| chr9:107706188 | rs2487030 | - | C>T | 273 | 196145 | 24.13 | 9.011e-07 | 0.7246 |
| chr25:2535445 | rs2174468 | - | A>G | 169 | 64696 | 23.99 | 9.671e-07 | 1.483 |
| chr19:34636136 | rs547878 | - | A>G | 189 | 74075 | 23.84 | 1.046e-06 | 1.454 |
| chr1:167837285 | rs203812 | ADCY10 | A>C | 45 | 12308 | 23.23 | 1.437e-06 | 2.042 |
| chr8:21500936 | rs10503712 | - | G>A | 86 | 28508 | 23.21 | 1.453e-06 | 1.694 |
| chr7:83642068 | rs117786586 | SEMA3A | C>A | 41 | 10919 | 23.03 | 1.594e-06 | 2.101 |
| chr23:50675928 | rs7889321 | - | A>G | 98 | 36941 | 22.72 | 1.876e-06 | 1.644 |
| chr12:24965708 | rs11047652 | BCAT1 | C>T | 809 | 391060 | 22.48 | 2.12e-06 | 1.254 |
| chr10:15885863 | rs12257572 | MINDY3 | A>C | 123 | 44678 | 22.44 | 2.168e-06 | 1.552 |
| chr18:58951545 | rs7227872 | - | C>T | 198 | 79035 | 22.21 | 2.444e-06 | 1.425 |
| chr10:25769873 | rs111833120 | GPR158 | G>C | 56 | 16563 | 22.18 | 2.487e-06 | 1.878 |
| chr3:159322105 | rs9852770 | IQCJ-SCHIP1 | T>C | 99 | 34308 | 22.16 | 2.512e-06 | 1.621 |
| chr2:208500311 | rs9288384 | - | C>A | 43 | 11825 | 21.74 | 3.116e-06 | 2.027 |
| chr9:107700958 | rs2487036 | - | A>G | 243 | 181117 | 25.22 | 5.106e-07 | 0.706 |
| chr7:83642068 | rs117786586 | SEMA3A | C>A | 41 | 10785 | 24.9 | 6.036e-07 | 2.163 |
| chr9:107706188 | rs2487030 | - | C>T | 251 | 185429 | 24.44 | 7.659e-07 | 0.7134 |
| chr1:1910236 | rs28651716 | CFAP74 | T>C | 464 | 309140 | 21.86 | 2.939e-06 | 0.7743 |
| chr10:1675929 | rs78047380 | ADARB2 | C>T | 60 | 18595 | 21.71 | 3.17e-06 | 1.831 |
| chr1:1912501 | rs35032062 | CFAP74 | A>G | 463 | 308243 | 21.42 | 3.684e-06 | 0.7761 |
| chr2:41726599 | rs78373771 | - | G>C | 77 | 25726 | 21.27 | 3.998e-06 | 1.704 |
| chr7:155223106 | rs13225426 | - | A>G | 545 | 257844 | 20.99 | 4.608e-06 | 1.271 |
| chr2:62481051 | rs60926739 | - | G>C | 444 | 204832 | 20.82 | 5.052e-06 | 1.288 |
| chr4:11354129 | rs116333103 | - | G>A | 37 | 9971 | 20.67 | 5.456e-06 | 2.097 |
| chr12:132912556 | rs117953392 | - | G>T | 42 | 11982 | 19.92 | 8.084e-06 | 1.984 |
| chr7:25561288 | rs6972342 | - | A>G | 172 | 69372 | 19.89 | 8.201e-06 | 1.43 |
| chr14:59481133 | rs2348831 | - | A>G | 177 | 134108 | 19.45 | 1.034e-05 | 0.7051 |
| chr17:48196396 | rs9915064 | SAMD14 | G>A | 46 | 13622 | 19.44 | 1.038e-05 | 1.914 |
| chr10:6488624 | rs118190892 | PRKCQ | G>A | 65 | 21293 | 19.41 | 1.054e-05 | 1.736 |
| chr12:63445092 | rs10506458 | - | G>A | 236 | 100831 | 19.28 | 1.127e-05 | 1.361 |
| chr12:24965708 | rs11047652 | BCAT1 | C>T | 735 | 361947 | 18.98 | 1.32e-05 | 1.241 |
| chr10:25769873 | rs111833120 | GPR158 | G>C | 49 | 14792 | 18.93 | 1.359e-05 | 1.863 |
| chr21:26587168 | rs17000769 | - | T>G | 278 | 121811 | 18.83 | 1.429e-05 | 1.33 |
| chr7:25579577 | rs17725870 | - | C>T | 214 | 90151 | 18.81 | 1.447e-05 | 1.373 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: T181 | Foreign body in oesophagus | 4/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: R061 | Stridor | 0/20 |