Case | Control |
---|---|
10027 | 450167 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr19:45422946 | rs4420638 | - | A>G | 4512 | 177999 | 94.32 | 2.681e-22 | 1.179 |
chr19:45410002 | rs769449 | APOE | G>A | 3004 | 114916 | 88.3 | 5.616e-21 | 1.206 |
chr19:45395619 | rs2075650 | TOMM40 | A>G | 3439 | 136972 | 58.34 | 2.203e-14 | 1.155 |
chr19:45395714 | rs157581 | TOMM40 | T>C | 5096 | 210451 | 47.2 | 6.4e-12 | 1.118 |
chr19:45414451 | rs439401 | - | C>T | 7360 | 347408 | 24.67 | 6.787e-07 | 0.9301 |
chr8:139302266 | rs78340141 | FAM135B | G>A | 641 | 23876 | 22.95 | 1.666e-06 | 1.215 |
chr13:46447104 | rs759960 | - | A>G | 1585 | 79998 | 22.85 | 1.755e-06 | 0.8816 |
chr5:101155096 | rs72770602 | - | C>T | 6915 | 325883 | 22.53 | 2.072e-06 | 0.9321 |
chr21:37579120 | rs77335750 | DOP1B | C>T | 636 | 23749 | 22.07 | 2.622e-06 | 1.211 |
chr18:13399272 | rs79328727 | LDLRAD4 | A>G | 233 | 14229 | 21.87 | 2.91e-06 | 0.7339 |
chr1:112129736 | rs17028048 | RAP1A | T>C | 2118 | 86478 | 21.5 | 3.53e-06 | 1.113 |
chr6:145518570 | rs62437750 | - | G>A | 1701 | 68693 | 20.65 | 5.525e-06 | 1.123 |
chr5:133887641 | rs41298956 | JADE2 | A>G | 496 | 27324 | 20.59 | 5.695e-06 | 0.8125 |
chr7:28210660 | rs520161 | JAZF1 | C>T | 6587 | 282573 | 20.56 | 5.789e-06 | 1.07 |
chr7:28185091 | rs849141 | JAZF1 | G>A | 6277 | 268909 | 20.36 | 6.429e-06 | 1.071 |
chr23:39833745 | rs5917908 | - | T>G | 3027 | 153322 | 20.32 | 6.567e-06 | 0.912 |
chr6:33552202 | rs549888 | - | A>G | 8310 | 388232 | 19.78 | 8.698e-06 | 0.9387 |
chr21:45180380 | Affx-18113854 | PDXK | A>G | 5188 | 220937 | 19.64 | 9.368e-06 | 1.074 |
chr20:12226412 | rs78479182 | - | G>A | 415 | 23219 | 19.57 | 9.694e-06 | 0.8018 |
chr21:19050937 | rs112926469 | - | C>A | 640 | 24202 | 19.51 | 9.999e-06 | 1.196 |
chr19:45422946 | rs4420638 | - | A>G | 4285 | 169311 | 84.65 | 3.568e-20 | 1.174 |
chr19:45410002 | rs769449 | APOE | G>A | 2911 | 111769 | 79.79 | 4.165e-19 | 1.199 |
chr19:45395619 | rs2075650 | TOMM40 | A>G | 3274 | 130493 | 53.01 | 3.317e-13 | 1.151 |
chr19:45395714 | rs157581 | TOMM40 | T>C | 4714 | 193713 | 46.21 | 1.064e-11 | 1.121 |
chr9:125548202 | rs11793583 | - | C>T | 2105 | 85012 | 25.72 | 3.941e-07 | 1.126 |
chr21:37579120 | rs77335750 | DOP1B | C>T | 630 | 23488 | 21.73 | 3.135e-06 | 1.21 |
chr19:45414451 | rs439401 | - | C>T | 6945 | 326374 | 21.04 | 4.5e-06 | 0.9335 |
chr8:139302266 | rs78340141 | FAM135B | G>A | 628 | 23540 | 20.49 | 5.994e-06 | 1.204 |
chr14:67128346 | rs7150227 | GPHN | A>G | 218 | 7229 | 19.74 | 8.857e-06 | 1.358 |
chr8:75155388 | rs12216776 | JPH1 | T>G | 256 | 8743 | 18.88 | 1.393e-05 | 1.318 |
chr5:101155096 | rs72770602 | - | C>T | 6589 | 308817 | 18.69 | 1.541e-05 | 0.9364 |
chr3:184303349 | rs61545883 | - | T>C | 3507 | 147240 | 18.66 | 1.558e-05 | 1.085 |
chr23:39833745 | rs5917908 | - | T>G | 2905 | 146833 | 18.53 | 1.676e-05 | 0.914 |
chr6:145518570 | rs62437750 | - | G>A | 1669 | 67574 | 18.51 | 1.69e-05 | 1.118 |
chr9:26153585 | rs16910205 | - | T>C | 1437 | 71984 | 18.5 | 1.696e-05 | 0.8879 |
chr4:74358308 | rs77466464 | AFM | G>C | 371 | 20805 | 18.45 | 1.743e-05 | 0.7972 |
chr21:19050937 | rs112926469 | - | C>A | 613 | 23162 | 18.42 | 1.776e-05 | 1.195 |
chr2:176745775 | rs34155645 | - | T>C | 1787 | 88349 | 18.16 | 2.035e-05 | 0.8988 |
chr7:16566645 | rs2301968 | SOSTDC1 | C>G | 2256 | 92886 | 18.15 | 2.037e-05 | 1.101 |
chr13:27471503 | rs61946191 | - | T>C | 1221 | 48669 | 18.03 | 2.17e-05 | 1.135 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr19:45422946 | rs4420638 | - | A>G | 4285 | 44336 | 80.92 | 2.351e-19 | 1.176 |
chr19:45410002 | rs769449 | APOE | G>A | 2911 | 29347 | 72.83 | 1.414e-17 | 1.196 |
chr19:45395619 | rs2075650 | TOMM40 | A>G | 3274 | 34213 | 49.54 | 1.942e-12 | 1.151 |
chr19:45395714 | rs157581 | TOMM40 | T>C | 4714 | 50544 | 48.0 | 4.263e-12 | 1.128 |
chr9:125548202 | rs11793583 | - | C>T | 2105 | 22186 | 26.1 | 3.234e-07 | 1.131 |
chr21:37579120 | rs77335750 | DOP1B | C>T | 630 | 6093 | 22.58 | 2.013e-06 | 1.223 |
chr14:67128346 | rs7150227 | GPHN | A>G | 218 | 1832 | 22.5 | 2.101e-06 | 1.405 |
chr14:67609692 | rs28410937 | GPHN | C>T | 214 | 1817 | 20.72 | 5.314e-06 | 1.39 |
chr8:75155388 | rs12216776 | JPH1 | T>G | 256 | 2237 | 20.68 | 5.424e-06 | 1.351 |
chr13:27471503 | rs61946191 | - | T>C | 1221 | 12604 | 20.52 | 5.914e-06 | 1.15 |
chr19:45414451 | rs439401 | - | C>T | 6945 | 85594 | 20.3 | 6.627e-06 | 0.9327 |
chr14:67724778 | rs10151131 | MPP5 | T>C | 261 | 2304 | 19.73 | 8.928e-06 | 1.338 |
chr1:63261652 | rs12122434 | ATG4C | A>G | 797 | 7982 | 19.7 | 9.071e-06 | 1.183 |
chr5:165043610 | rs80167075 | - | G>A | 3723 | 40943 | 19.33 | 1.098e-05 | 1.087 |
chr3:184303349 | rs61545883 | - | T>C | 3507 | 38474 | 19.21 | 1.17e-05 | 1.089 |
chr21:19050937 | rs112926469 | - | C>A | 613 | 6017 | 18.98 | 1.323e-05 | 1.206 |
chr7:16566645 | rs2301968 | SOSTDC1 | C>G | 2256 | 24242 | 18.89 | 1.382e-05 | 1.107 |
chr5:101155096 | rs72770602 | - | C>T | 6589 | 81037 | 18.53 | 1.673e-05 | 0.9349 |
chr1:247125355 | rs11579381 | ZNF670-ZNF695 | C>T | 6539 | 80480 | 18.07 | 2.127e-05 | 0.9353 |
chr11:115783437 | rs61899166 | - | T>C | 540 | 7644 | 17.74 | 2.529e-05 | 0.827 |