Nonarteritic anterior ischemic optic neuropathy



No Female GWAS available for 0007634


No Male GWAS available for 0007634


Female Case Female Control % Female
147 249710 65%
Male Case Male Control % Male
78 210259 35%

Phenotype Definition

An acute condition characterized by sudden visual loss (usually discovered in the morning), optic disc edema at onset, optic disc-related visual field defects. Nonarteritic anterior ischemic optic neuropathy can be associated with flame hemorrhages on the swollen disc or nearby neuroretinal layer, and sometimes with nearby cotton-wool exudates. [HPO:probinson, PMID:17698200]

Phenotype Comment

Nonarteritic anterior ischemic optic neuropathy is caused by infarction of the laminar or retrolaminar portion of the optic nerve head supplied by the short posterior ciliary arteries. Clinically NAION is characterized by sudden, usually painless, loss of vision in one or both eyes. Examination findings include decreased visual acuity, a visual field defect, decreased colour vision, a relative afferent pupillary defect, and optic disc swelling.

Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: H050 Acute inflammation of orbit 4/20