0008419

Case	Control
22786	437408

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr23:64367019	rs7064929	-	G>A	1214	16352	117.1	2.795e-27	1.385
chr1:159174683	rs2814778	ACKR1	T>C	1282	18095	105.8	8.317e-25	1.35
chr12:132549300	rs7136109	EP400	A>G	757	9873	99.68	1.794e-23	1.458
chr8:145639681	rs1871534	SLC39A4	G>C	1196	16949	96.49	8.976e-23	1.345
chr23:148151708	Affx-34694529	-	A>C	656	8195	95.54	1.451e-22	1.488
chr9:117110112	Affx-52344420	AKNA	T>TG	986	13593	94.43	2.545e-22	1.38
chr23:109671384	rs768312	AMMECR1	T>C	1066	14573	93.08	5.012e-22	1.362
chr23:63423664	rs5964740	AMER1	C>T	1560	22540	92.15	8.054e-22	1.291
chr23:63410110	rs61730681	AMER1	T>C	1561	22572	91.59	1.068e-21	1.29
chr23:53347028	rs1547218	IQSEC2	T>C	2417	36836	89.65	2.841e-21	1.227
chr9:129979758	rs3780318	RALGPS1	G>A	1076	15165	89.34	3.331e-21	1.35
chr16:129223	rs710079	MPG	C>T	1747	26295	88.94	4.074e-21	1.267
chr17:29298304	rs7225888	RNF135	C>G	1288	18647	88.69	4.607e-21	1.315
chr23:106146349	rs5962774	MORC4	T>C	781	10245	87.8	7.243e-21	1.418
chr15:45556163	rs8023604	SLC28A2	T>C	878	12033	87.07	1.049e-20	1.388
chr23:110685534	rs16986503	-	C>T	868	11615	86.46	1.429e-20	1.39
chr17:29290106	rs55861543	-	C>T	1329	19430	85.32	2.536e-20	1.303
chr5:33951693	rs16891982	SLC45A2	G>C	3868	63190	84.79	3.318e-20	1.172
chr23:142717383	rs73577386	SLITRK4	A>G	568	7054	84.76	3.372e-20	1.495
chr9:129984107	rs3739553	RALGPS1	G>A	1019	14394	83.21	7.394e-20	1.347
chr15:67367706	rs1498507	SMAD3	A>C	20362	404321	42.09	8.706e-11	0.9392
chr6:34546560	rs2814982	-	C>T	5038	88814	38.43	5.68e-10	1.1
chr2:182687502	rs72891049	-	A>G	3466	72692	28.61	8.87e-08	0.9078
chr9:31233220	rs13292646	-	T>C	14895	296260	26.77	2.29e-07	0.9484
chr9:31144887	rs13286518	-	A>G	14355	285706	26.65	2.439e-07	0.948
chr1:227309961	rs596131	CDC42BPA	A>G	11618	232683	26.55	2.57e-07	0.9448
chr1:198237879	rs3885821	NEK7	C>T	5108	91503	25.72	3.949e-07	1.08
chr6:34616322	rs3800461	ILRUN	G>C	5516	99197	25.38	4.716e-07	1.077
chr1:198214462	rs12046935	NEK7	G>A	4953	88454	25.36	4.748e-07	1.081
chr7:27240482	rs3807598	-	C>G	20884	390741	24.78	6.434e-07	1.05
chr19:33281924	rs11881633	TDRD12	G>A	21426	421681	24.38	7.896e-07	0.9535
chr21:46487831	rs2838762	-	C>A	19623	366343	24.36	8.006e-07	1.049
chr3:50070763	rs7621352	RBM6	A>C	20786	409263	24.16	8.864e-07	0.9537
chr1:198299057	rs6660389	-	G>A	6479	117350	24.05	9.407e-07	1.07
chr3:49941436	rs2280406	-	G>A	23552	441824	23.74	1.1e-06	1.048
chr2:113936106	rs45491191	PSD4	A>G	4848	99428	22.96	1.655e-06	0.9282
chr19:33254878	rs2868188	TDRD12	G>A	21587	424415	22.44	2.167e-06	0.9554
chr6:34552797	rs2814944	-	G>A	7033	127976	22.36	2.261e-06	1.065
chr19:1957079	rs11084923	CSNK1G2	T>C	19790	389966	22.3	2.332e-06	0.9552
chr19:33246317	rs10404914	TDRD12	G>A	21490	422293	22.22	2.428e-06	0.9556

Location

SNP

Gene

Ref>Alt

Alt in Case

Alt in Control

Chi-square

P-value

Odds ratio

chr23:64367019

rs7064929

-

G>A

1214

16352

117.1

2.795e-27

1.385

chr1:159174683

rs2814778

ACKR1

T>C

1282

18095

105.8

8.317e-25

1.35

chr12:132549300

rs7136109

EP400

A>G

757

9873

99.68

1.794e-23

1.458

chr8:145639681

rs1871534

SLC39A4

G>C

1196

16949

96.49

8.976e-23

1.345

chr23:148151708

Affx-34694529

-

A>C

656

8195

95.54

1.451e-22

1.488

chr9:117110112

Affx-52344420

AKNA

T>TG

986

13593

94.43

2.545e-22

1.38

chr23:109671384

rs768312

AMMECR1

T>C

1066

14573

93.08

5.012e-22

1.362

chr23:63423664

rs5964740

AMER1

C>T

1560

22540

92.15

8.054e-22

1.291

chr23:63410110

rs61730681

AMER1

T>C

1561

22572

91.59

1.068e-21

1.29

chr23:53347028

rs1547218

IQSEC2

T>C

2417

36836

89.65

2.841e-21

1.227

chr9:129979758

rs3780318

RALGPS1

G>A

1076

15165

89.34

3.331e-21

1.35

chr16:129223

rs710079

MPG

C>T

1747

26295

88.94

4.074e-21

1.267

chr17:29298304

rs7225888

RNF135

C>G

1288

18647

88.69

4.607e-21

1.315

chr23:106146349

rs5962774

MORC4

T>C

781

10245

87.8

7.243e-21

1.418

chr15:45556163

rs8023604

SLC28A2

T>C

878

12033

87.07

1.049e-20

1.388

chr23:110685534

rs16986503

-

C>T

868

11615

86.46

1.429e-20

1.39

chr17:29290106

rs55861543

-

C>T

1329

19430

85.32

2.536e-20

1.303

chr5:33951693

rs16891982

SLC45A2

G>C

3868

63190

84.79

3.318e-20

1.172

chr23:142717383

rs73577386

SLITRK4

A>G

568

7054

84.76

3.372e-20

1.495

chr9:129984107

rs3739553

RALGPS1

G>A

1019

14394

83.21

7.394e-20

1.347

chr15:67367706

rs1498507

SMAD3

A>C

20362

404321

42.09

8.706e-11

0.9392

chr6:34546560

rs2814982

-

C>T

5038

88814

38.43

5.68e-10

1.1

chr2:182687502

rs72891049

-

A>G

3466

72692

28.61

8.87e-08

0.9078

chr9:31233220

rs13292646

-

T>C

14895

296260

26.77

2.29e-07

0.9484

chr9:31144887

rs13286518

-

A>G

14355

285706

26.65

2.439e-07

0.948

chr1:227309961

rs596131

CDC42BPA

A>G

11618

232683

26.55

2.57e-07

0.9448

chr1:198237879

rs3885821

NEK7

C>T

5108

91503

25.72

3.949e-07

1.08

chr6:34616322

rs3800461

ILRUN

G>C

5516

99197

25.38

4.716e-07

1.077

chr1:198214462

rs12046935

NEK7

G>A

4953

88454

25.36

4.748e-07

1.081

chr7:27240482

rs3807598

-

C>G

20884

390741

24.78

6.434e-07

1.05

chr19:33281924

rs11881633

TDRD12

G>A

21426

421681

24.38

7.896e-07

0.9535

chr21:46487831

rs2838762

-

C>A

19623

366343

24.36

8.006e-07

1.049

chr3:50070763

rs7621352

RBM6

A>C

20786

409263

24.16

8.864e-07

0.9537

chr1:198299057

rs6660389

-

G>A

6479

117350

24.05

9.407e-07

1.07

chr3:49941436

rs2280406

-

G>A

23552

441824

23.74

1.1e-06

1.048

chr2:113936106

rs45491191

PSD4

A>G

4848

99428

22.96

1.655e-06

0.9282

chr19:33254878

rs2868188

TDRD12

G>A

21587

424415

22.44

2.167e-06

0.9554

chr6:34552797

rs2814944

-

G>A

7033

127976

22.36

2.261e-06

1.065

chr19:1957079

rs11084923

CSNK1G2

T>C

19790

389966

22.3

2.332e-06

0.9552

chr19:33246317

rs10404914

TDRD12

G>A

21490

422293

22.22

2.428e-06

0.9556

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr15:67367706	rs1498507	SMAD3	A>C	20362	106040	31.5	1.994e-08	0.9437
chr1:227309961	rs596131	CDC42BPA	A>G	11618	61352	26.85	2.204e-07	0.941
chr6:34546560	rs2814982	-	C>T	5038	23600	25.79	3.799e-07	1.087
chr1:198299057	rs6660389	-	G>A	6479	30861	20.81	5.073e-06	1.07
chr9:31233220	rs13292646	-	T>C	14895	77698	20.18	7.039e-06	0.9521
chr9:31144887	rs13286518	-	A>G	14355	74933	20.11	7.296e-06	0.9518
chr7:27240482	rs3807598	-	C>G	20884	102920	19.46	1.026e-05	1.047
chr2:182687502	rs72891049	-	A>G	3466	18894	19.2	1.18e-05	0.9192
chr1:227351712	rs6426573	CDC42BPA	G>T	12616	66015	19.1	1.243e-05	0.9512
chr2:113936106	rs45491191	PSD4	A>G	4848	26066	18.58	1.63e-05	0.9311
chr11:8302755	rs7929080	-	G>A	13146	64088	18.52	1.684e-05	1.05
chr20:43435676	rs61078127	RIMS4	C>A	1561	7004	18.39	1.797e-05	1.13
chr4:173105236	rs76470327	GALNTL6	C>T	2391	13235	18.29	1.895e-05	0.907
chr9:86065188	rs11140095	FRMD3	G>A	1691	7624	18.24	1.945e-05	1.124
chr5:45987518	rs75346245	-	G>T	3799	20587	18.07	2.127e-05	0.9245
chr21:33221812	rs35343964	-	T>C	7406	39253	17.91	2.312e-05	0.943
chr4:180250564	rs17817727	-	C>T	7974	42203	17.9	2.334e-05	0.9447
chr9:3804237	rs117717271	-	T>G	786	4663	17.84	2.398e-05	0.8486
chr5:43663640	rs62367650	NNT	G>A	3069	16771	17.75	2.521e-05	0.9179
chr2:69648520	rs7559850	NFU1	T>C	18925	93067	17.59	2.735e-05	1.045

ID	Name	Top Correlation
ICD: M545	Low back pain	12/20
ICD: M549	Dorsalgia, unspecified	12/20

ID	Name	Top Correlation
ICD-10: G551	Nerve root and plexus compressions in intervertebral disk disorders	0/20
ICD-10: M431	Spondylolisthesis	0/20
ICD-10: M501	Cervical disk disorder with radiculopathy	0/20
ICD-10: M503	Other cervical disk degeneration	0/20
ICD-10: M511	Lumbar and other intervertebral disk disorders with radiculopathy	0/20
ICD-10: M512	Other specified intervertebral disk displacement	0/20
ICD-10: M513	Other specified intervertebral disk degeneration	0/20
ICD-10: M518	Other specified intervertebral disk disorders	0/20
ICD-10: M519	Intervertebral disk disorder, unspecified	0/20

Intervertebral disc degeneration

0008419

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information

Associated Diseases ^ⓘ

Intervertebral disc degeneration

0008419

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ