Statistics
| Case | Control |
|---|---|
| 1483 | 458711 |
Phenotype Definition
The presence of a diverticulum (sac or pouch) in the wall of the urethra. [HPO:curators]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr10:115627055 | rs78384060 | NHLRC2 | A>G | 111 | 21501 | 26.03 | 3.36e-07 | 1.632 |
| chr12:1633173 | rs80261425 | - | C>T | 159 | 33839 | 24.05 | 9.397e-07 | 1.488 |
| chr3:69165081 | rs62255470 | LMOD3 | T>C | 96 | 18518 | 22.7 | 1.893e-06 | 1.633 |
| chr18:37991896 | rs77993724 | - | A>G | 163 | 35451 | 22.04 | 2.672e-06 | 1.457 |
| chr2:56351058 | rs75818885 | - | C>G | 154 | 33189 | 21.81 | 3.017e-06 | 1.469 |
| chr8:65193106 | rs77907407 | - | C>T | 85 | 16185 | 21.29 | 3.953e-06 | 1.654 |
| chr1:163413540 | rs111888546 | - | A>G | 136 | 28944 | 20.76 | 5.213e-06 | 1.489 |
| chr10:134082826 | rs74161756 | STK32C | G>A | 169 | 37540 | 20.54 | 5.837e-06 | 1.43 |
| chr14:94479835 | rs11851944 | - | C>T | 435 | 165133 | 20.49 | 5.996e-06 | 0.7916 |
| chr17:52818321 | rs34838222 | - | C>T | 531 | 138634 | 19.78 | 8.704e-06 | 1.236 |
| chr16:79943873 | rs7187277 | - | A>G | 459 | 117666 | 19.37 | 1.075e-05 | 1.249 |
| chr17:10380939 | rs4791991 | - | G>C | 257 | 61493 | 19.19 | 1.184e-05 | 1.33 |
| chr17:10451474 | rs7215791 | MYH2 | T>C | 253 | 60453 | 18.85 | 1.417e-05 | 1.329 |
| chr19:6984125 | rs72995089 | - | T>C | 119 | 25205 | 18.55 | 1.655e-05 | 1.493 |
| chr5:71144626 | rs76941444 | - | G>A | 220 | 51783 | 18.35 | 1.834e-05 | 1.349 |
| chr7:41851374 | rs77737758 | - | C>T | 130 | 27998 | 18.32 | 1.872e-05 | 1.465 |
| chr3:68904164 | rs62256069 | TAFA4 | A>G | 73 | 13899 | 18.24 | 1.945e-05 | 1.652 |
| chr1:85269521 | rs72716996 | - | A>G | 130 | 28027 | 18.11 | 2.084e-05 | 1.462 |
| chr3:17231524 | rs114362220 | TBC1D5 | T>C | 207 | 48372 | 18.08 | 2.121e-05 | 1.357 |
| chr3:35250224 | rs34123676 | - | C>T | 922 | 254283 | 18.05 | 2.15e-05 | 1.181 |
| chr12:1633173 | rs80261425 | - | C>T | 157 | 33408 | 22.89 | 1.713e-06 | 1.478 |
| chr10:115627055 | rs78384060 | NHLRC2 | A>G | 107 | 21113 | 22.39 | 2.222e-06 | 1.589 |
| chr8:65193106 | rs77907407 | - | C>T | 84 | 15789 | 21.54 | 3.459e-06 | 1.665 |
| chr2:56351058 | rs75818885 | - | C>G | 151 | 32437 | 20.94 | 4.744e-06 | 1.463 |
| chr11:68851414 | rs2376558 | TPCN2 | C>T | 31 | 4336 | 20.55 | 5.813e-06 | 2.225 |
| chr6:116575083 | rs2232470 | TSPYL4 | A>C | 995 | 344643 | 20.11 | 7.306e-06 | 0.8398 |
| chr11:68817229 | rs4930259 | TPCN2 | T>C | 32 | 4564 | 20.08 | 7.434e-06 | 2.18 |
| chr6:116658955 | rs2501052 | DSE | G>A | 996 | 344667 | 20.05 | 7.559e-06 | 0.84 |
| chr1:106117026 | rs5001988 | - | A>G | 84 | 16103 | 19.85 | 8.379e-06 | 1.632 |
| chr18:37991896 | rs77993724 | - | A>G | 158 | 34584 | 19.8 | 8.596e-06 | 1.437 |
| chr8:93977436 | rs16915399 | TRIQK | T>C | 82 | 15647 | 19.78 | 8.669e-06 | 1.639 |
| chr1:163413540 | rs111888546 | - | A>G | 134 | 28518 | 19.75 | 8.832e-06 | 1.479 |
| chr3:69165081 | rs62255470 | LMOD3 | T>C | 90 | 17584 | 19.51 | 1.003e-05 | 1.599 |
| chr1:204494576 | rs4252675 | MDM4 | T>C | 211 | 48642 | 19.24 | 1.151e-05 | 1.367 |
| chr5:10735379 | rs55809554 | DAP | C>T | 264 | 62998 | 19.15 | 1.209e-05 | 1.326 |
| chr23:23395694 | rs186609862 | PTCHD1 | T>G | 36 | 5030 | 18.91 | 1.369e-05 | 2.049 |
| chr5:38907814 | rs73751809 | OSMR | C>T | 163 | 36166 | 18.81 | 1.441e-05 | 1.417 |
| chr6:116563547 | rs1204822 | NT5DC1 | G>A | 1041 | 357135 | 18.61 | 1.601e-05 | 0.8469 |
| chr23:37877977 | rs62586981 | AF241726.2 | C>G | 81 | 14366 | 18.53 | 1.674e-05 | 1.621 |
| chr1:85269521 | rs72716996 | - | A>G | 129 | 27579 | 18.14 | 2.055e-05 | 1.465 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr12:1633173 | rs80261425 | - | C>T | 157 | 1116 | 24.33 | 8.119e-07 | 1.535 |
| chr7:158051019 | rs118041716 | PTPRN2 | C>T | 82 | 506 | 22.38 | 2.24e-06 | 1.756 |
| chr8:3060512 | rs60520984 | CSMD1 | A>C | 1162 | 13801 | 21.1 | 4.357e-06 | 0.8349 |
| chr11:2021075 | rs2107425 | - | C>T | 975 | 9206 | 20.54 | 5.854e-06 | 1.204 |
| chr5:38907814 | rs73751809 | OSMR | C>T | 163 | 1210 | 20.37 | 6.366e-06 | 1.469 |
| chr6:87248703 | rs6903888 | - | T>C | 715 | 6560 | 19.62 | 9.446e-06 | 1.221 |
| chr6:116575083 | rs2232470 | TSPYL4 | A>C | 995 | 11973 | 19.53 | 9.911e-06 | 0.8359 |
| chr6:116658955 | rs2501052 | DSE | G>A | 996 | 11958 | 19.3 | 1.115e-05 | 0.8367 |
| chr23:23395694 | rs186609862 | PTCHD1 | T>G | 36 | 146 | 19.07 | 1.262e-05 | 2.219 |
| chr20:38782947 | rs7271724 | - | A>G | 1239 | 11963 | 18.85 | 1.417e-05 | 1.184 |
| chr20:12464082 | rs6041383 | - | C>T | 107 | 739 | 18.84 | 1.424e-05 | 1.573 |
| chr2:126934533 | rs28494186 | - | A>C | 97 | 1610 | 18.8 | 1.455e-05 | 0.633 |
| chr6:116563547 | rs1204822 | NT5DC1 | G>A | 1041 | 12430 | 18.8 | 1.453e-05 | 0.8403 |
| chr20:19538337 | rs118065979 | SLC24A3 | G>A | 63 | 377 | 18.76 | 1.484e-05 | 1.799 |
| chr6:43526737 | rs17287964 | POLR1C | A>G | 293 | 2438 | 18.43 | 1.763e-05 | 1.321 |
| chr2:127060704 | rs7585599 | - | C>T | 53 | 1019 | 18.35 | 1.837e-05 | 0.5486 |
| chr3:35250224 | rs34123676 | - | C>T | 901 | 8478 | 18.28 | 1.907e-05 | 1.196 |
| chr3:127715133 | rs1549874 | MGLL | A>G | 365 | 4849 | 18.22 | 1.966e-05 | 0.7809 |
| chr13:106062530 | rs1924762 | - | T>C | 314 | 2638 | 18.15 | 2.037e-05 | 1.307 |
| chr3:17231524 | rs114362220 | TBC1D5 | T>C | 203 | 1602 | 17.92 | 2.302e-05 | 1.384 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|