Statistics
| Case | Control |
|---|---|
| 3142 | 457052 |
Phenotype Definition
The presence of two or more accessory spleens. [HPO:curators]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr3:38051211 | rs75495843 | PLCD1 | G>A | 269 | 28739 | 28.48 | 9.484e-08 | 1.394 |
| chr14:75699566 | rs60699541 | - | C>G | 1494 | 194909 | 26.44 | 2.724e-07 | 1.164 |
| chr5:1315660 | rs4975616 | - | A>G | 2577 | 408239 | 23.81 | 1.061e-06 | 0.8838 |
| chr14:75572265 | rs96358 | ZC2HC1C | G>A | 2677 | 365894 | 23.28 | 1.404e-06 | 1.129 |
| chr6:31800868 | rs2471980 | - | G>C | 2001 | 321403 | 22.95 | 1.66e-06 | 0.8791 |
| chr14:75459633 | rs175016 | - | C>T | 3268 | 453702 | 22.32 | 2.302e-06 | 1.125 |
| chr9:109538577 | rs7858184 | - | T>G | 987 | 126472 | 22.24 | 2.404e-06 | 1.177 |
| chr1:213068127 | rs41301013 | FLVCR1 | C>T | 259 | 28613 | 21.92 | 2.845e-06 | 1.346 |
| chr1:212852806 | rs12138919 | - | C>T | 251 | 27625 | 21.72 | 3.161e-06 | 1.35 |
| chr5:85511883 | rs72772345 | - | T>C | 327 | 37513 | 21.36 | 3.807e-06 | 1.3 |
| chr5:1322087 | rs401681 | CLPTM1L | C>T | 2685 | 422983 | 21.31 | 3.917e-06 | 0.8903 |
| chr23:93056170 | rs62597059 | - | G>C | 854 | 110478 | 21.31 | 3.903e-06 | 1.19 |
| chr6:16180557 | rs114862361 | - | T>C | 255 | 28267 | 21.3 | 3.924e-06 | 1.343 |
| chr7:138317237 | rs28617498 | SVOPL | G>A | 59 | 15589 | 21.04 | 4.487e-06 | 0.553 |
| chr3:66477828 | rs75178583 | LRIG1 | A>G | 518 | 62715 | 20.87 | 4.908e-06 | 1.233 |
| chr5:85393840 | rs72772174 | - | A>G | 331 | 38087 | 20.87 | 4.916e-06 | 1.294 |
| chr6:31783507 | rs1043618 | HSPA1A | G>C | 2364 | 374620 | 20.72 | 5.302e-06 | 0.8892 |
| chr14:75532941 | rs7156328 | ACYP1 | T>C | 2916 | 456769 | 20.7 | 5.381e-06 | 0.8928 |
| chr14:75455810 | rs175012 | - | A>C | 3208 | 445220 | 20.69 | 5.397e-06 | 1.119 |
| chr14:75626042 | rs910316 | TMED10 | A>C | 2937 | 459092 | 20.69 | 5.411e-06 | 0.8931 |
| chr14:75699566 | rs60699541 | - | C>G | 1442 | 185548 | 26.33 | 2.883e-07 | 1.167 |
| chr5:1315660 | rs4975616 | - | A>G | 2452 | 384774 | 24.25 | 8.463e-07 | 0.8801 |
| chr13:74871188 | rs9543560 | - | C>A | 1099 | 139303 | 23.94 | 9.95e-07 | 1.177 |
| chr5:1322087 | rs401681 | CLPTM1L | C>T | 2566 | 400932 | 22.78 | 1.812e-06 | 0.8843 |
| chr14:75572265 | rs96358 | ZC2HC1C | G>A | 2585 | 349061 | 22.73 | 1.866e-06 | 1.13 |
| chr14:75459633 | rs175016 | - | C>T | 3127 | 428118 | 22.66 | 1.929e-06 | 1.129 |
| chr3:38051211 | rs75495843 | PLCD1 | G>A | 253 | 27604 | 21.54 | 3.462e-06 | 1.347 |
| chr23:93056170 | rs62597059 | - | G>C | 825 | 105163 | 21.43 | 3.67e-06 | 1.194 |
| chr21:32497674 | rs2833283 | TIAM1 | A>C | 259 | 28378 | 21.17 | 4.208e-06 | 1.34 |
| chr6:31800868 | rs2471980 | - | G>C | 1875 | 297247 | 21.03 | 4.525e-06 | 0.8809 |
| chr10:122247789 | rs17705622 | PLPP4 | A>G | 549 | 66187 | 20.91 | 4.802e-06 | 1.227 |
| chr4:108094603 | rs72667821 | DKK2 | C>T | 327 | 37125 | 20.85 | 4.963e-06 | 1.297 |
| chr14:75532941 | rs7156328 | ACYP1 | T>C | 2802 | 434077 | 20.7 | 5.359e-06 | 0.8905 |
| chr14:75626042 | rs910316 | TMED10 | A>C | 2811 | 434626 | 20.58 | 5.705e-06 | 0.8909 |
| chr14:75538217 | rs3742778 | ZC2HC1C | G>T | 2782 | 428398 | 20.48 | 6.014e-06 | 0.8906 |
| chr3:66477828 | rs75178583 | LRIG1 | A>G | 486 | 57914 | 20.33 | 6.506e-06 | 1.238 |
| chr9:109538577 | rs7858184 | - | T>G | 956 | 121701 | 19.98 | 7.829e-06 | 1.171 |
| chr5:85511883 | rs72772345 | - | T>C | 324 | 36991 | 19.96 | 7.918e-06 | 1.291 |
| chr14:75590822 | rs8017642 | NEK9 | G>A | 2809 | 434322 | 19.87 | 8.302e-06 | 0.8926 |
| chr14:75574087 | rs10146482 | ZC2HC1C | C>T | 2804 | 434402 | 19.84 | 8.429e-06 | 0.8927 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr5:33951693 | rs16891982 | SLC45A2 | G>C | 362 | 1206 | 37.48 | 9.218e-10 | 0.6862 |
| chr19:440478 | rs2075018 | SHC2 | G>C | 256 | 890 | 33.19 | 8.371e-09 | 0.6603 |
| chr3:66430870 | Affx-22621685 | SLC25A26 | G>A | 533 | 953 | 26.99 | 2.048e-07 | 1.338 |
| chr12:33058062 | rs4931655 | - | A>G | 447 | 1371 | 26.98 | 2.056e-07 | 0.746 |
| chr2:200142591 | rs994185 | SATB2 | C>T | 694 | 2007 | 26.21 | 3.057e-07 | 0.7875 |
| chr5:54201566 | rs73128671 | - | G>A | 1388 | 3748 | 26.08 | 3.273e-07 | 0.8339 |
| chr14:106054456 | rs61984162 | - | G>A | 256 | 849 | 25.26 | 5.004e-07 | 0.6946 |
| chr19:475667 | rs61277751 | - | G>T | 249 | 831 | 25.26 | 5.013e-07 | 0.6914 |
| chr7:138317237 | rs28617498 | SVOPL | G>A | 59 | 278 | 25.18 | 5.212e-07 | 0.4923 |
| chr3:55449045 | rs3846040 | - | T>C | 88 | 368 | 25.04 | 5.611e-07 | 0.5542 |
| chr6:31800868 | rs2471980 | - | G>C | 2001 | 5214 | 24.97 | 5.809e-07 | 0.8532 |
| chr19:33874354 | rs75826800 | - | C>T | 1737 | 3591 | 24.79 | 6.404e-07 | 1.183 |
| chr6:31794592 | rs2763979 | - | C>T | 2189 | 5666 | 24.57 | 7.169e-07 | 0.8574 |
| chr6:31783507 | rs1043618 | HSPA1A | G>C | 2364 | 6077 | 24.31 | 8.208e-07 | 0.8602 |
| chr5:33958959 | rs28777 | SLC45A2 | A>C | 320 | 1017 | 24.28 | 8.319e-07 | 0.7238 |
| chr4:25822281 | rs10939083 | SEL1L3 | G>A | 209 | 713 | 24.15 | 8.893e-07 | 0.6762 |
| chr19:2394853 | rs75280324 | TMPRSS9 | G>A | 958 | 1874 | 23.93 | 1e-06 | 1.232 |
| chr2:66939510 | rs76079223 | - | C>T | 151 | 213 | 23.66 | 1.149e-06 | 1.677 |
| chr6:31851234 | rs652888 | EHMT2 | A>G | 1418 | 3780 | 23.05 | 1.581e-06 | 0.844 |
| chr11:81321935 | rs74568444 | - | T>C | 116 | 442 | 22.69 | 1.904e-06 | 0.6083 |
| chr3:66430870 | Affx-22621685 | SLC25A26 | G>A | 517 | 897 | 26.74 | 2.329e-07 | 1.345 |
| chr11:81321935 | rs74568444 | - | T>C | 113 | 430 | 24.46 | 7.605e-07 | 0.593 |
| chr6:29546799 | rs1233396 | GABBR1 | G>A | 757 | 2100 | 24.26 | 8.434e-07 | 0.7999 |
| chr6:32109979 | rs204999 | - | A>G | 1792 | 4586 | 23.98 | 9.749e-07 | 0.85 |
| chr6:31851234 | rs652888 | EHMT2 | A>G | 1359 | 3550 | 23.9 | 1.017e-06 | 0.8377 |
| chr6:29548089 | rs926552 | GABBR1 | G>A | 758 | 2100 | 23.9 | 1.016e-06 | 0.8013 |
| chr6:32155581 | rs204993 | PBX2 | A>G | 1845 | 4702 | 23.72 | 1.115e-06 | 0.8519 |
| chr5:54201566 | rs73128671 | - | G>A | 1352 | 3538 | 23.26 | 1.415e-06 | 0.8394 |
| chr6:32059867 | rs1150753 | TNXB | A>G | 742 | 2048 | 22.66 | 1.936e-06 | 0.8044 |
| chr6:32064726 | rs1150752 | TNXB | T>C | 743 | 2050 | 22.54 | 2.057e-06 | 0.8049 |
| chr6:32156908 | rs204992 | PBX2 | G>A | 1471 | 3802 | 22.52 | 2.077e-06 | 0.8459 |
| chr6:32080191 | rs1269852 | TNXB | G>C | 738 | 2034 | 22.05 | 2.656e-06 | 0.8063 |
| chr6:31940897 | rs389884 | STK19 | A>G | 744 | 2050 | 22.04 | 2.668e-06 | 0.8069 |
| chr6:32154998 | rs204994 | PBX2 | C>T | 1470 | 3805 | 22.01 | 2.71e-06 | 0.8474 |
| chr6:32158319 | rs176095 | - | A>G | 1473 | 3802 | 21.76 | 3.088e-06 | 0.8483 |
| chr3:66477828 | rs75178583 | LRIG1 | A>G | 486 | 860 | 21.6 | 3.354e-06 | 1.314 |
| chr6:31918860 | rs1270942 | AL645922.1 | A>G | 745 | 2046 | 21.48 | 3.575e-06 | 0.8092 |
| chr4:44261451 | rs73245591 | KCTD8 | G>T | 213 | 327 | 21.35 | 3.821e-06 | 1.507 |
| chr6:31870326 | rs558702 | C2 | G>A | 743 | 2036 | 21.13 | 4.297e-06 | 0.8103 |
| chr6:31058340 | rs3130544 | - | C>A | 859 | 2324 | 21.1 | 4.362e-06 | 0.8204 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: L720 | Epidermal cyst | 10/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: C252 | Tail of pancreas | 0/20 |
| ICD-10: D759 | Disease of blood and blood-forming organs, unspecified | 0/20 |