Stridor

0010307

Normal Case/Contol

GWAS of 0010307

Sibling Case/Control

No sibling GWAS available 0010307

Statistics

Case Control
1947 458247

Phenotype Definition

Stridor is a high pitched sound resulting from turbulent air flow in the upper airway. [HPO:probinson, PMID:26229557]

Phenotype Comment

Stridor is different from wheezing by the following reasons. It is louder over the neck than chest wall. Secondly; stridor is mainly inspiratory. If occurs in expiration, it is usually biphasic. On the other hand; wheeze is mainly expiratory and occurs during both phases. It indicates extrathoracic upper-airway obstruction (supraglottic lesions like laryngomalacia, vocal cord lesion) when heard on inspiration. It occurs in expiration if associated with intrathoracic tracheobronchial lesions (tracheomalacia, bronchomalacia, and extrinsic compression). It occurs in both phases if lesion is fixed, for example, stenosis. Stridor is caused by the turbulent flow passing through a narrowed segment of the upper respiratory tract.


Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: J384 Oedema of larynx 1/20