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ICD-10
HPO
Compare GWAS
Super Class
Abnormal cardiovascular system physiology
Sub Class
Internal hemorrhage
Abnormality of blood volume homeostasis
Cardiac shunt
Abnormality of blood circulation
0011028
Normal Case/Contol
ⓘ
Sibling Case/Control
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
136396
323798
Phenotype Definition
An abnormality of blood circulation. [HPO:probinson]
Top SNP Information
Show Normal Table
Show Sibling SNP
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds ratio
chr6:93667780
rs9363020
-
G>A
3191
8800
51.65
6.634e-13
0.8614
chr15:48426484
rs1426654
SLC24A5
A>G
7609
19917
51.33
7.81e-13
0.9068
chr7:89690199
rs1990160
-
T>C
8308
21651
50.96
9.423e-13
0.9107
chr12:110171036
rs73407761
FAM222A
C>T
4880
13048
49.07
2.466e-12
0.8882
chr5:33958959
rs28777
SLC45A2
A>C
16130
40862
47.76
4.819e-12
0.936
chr6:93645908
rs77956657
-
T>C
4160
11166
44.74
2.25e-11
0.8848
chr4:68102416
rs4860240
-
T>C
7302
19024
44.49
2.554e-11
0.9112
chr6:396321
rs12203592
IRF4
C>T
60777
140428
44.37
2.719e-11
1.037
chr13:58656599
rs9563574
-
T>C
49607
121836
42.25
8.02e-11
0.9626
chr16:57068106
rs3995818
NLRC5
A>G
4046
10838
41.85
9.84e-11
0.8869
chr5:33951693
rs16891982
SLC45A2
G>C
19101
47957
41.81
1.005e-10
0.9443
chr6:170602429
rs17860704
DLL1
T>C
3150
8568
41.71
1.059e-10
0.8735
chr7:114119935
rs17372022
FOXP2
T>G
71018
165041
41.01
1.512e-10
1.034
chr17:9502283
rs73253863
CFAP52
T>G
9516
24440
41.0
1.521e-10
0.9243
chr6:32577973
rs532965
-
T>G
54517
126020
40.62
1.848e-10
1.037
chr16:10882632
rs1830370
TVP23A
C>G
10784
27544
40.34
2.139e-10
0.9291
chr10:21834536
rs7098100
MLLT10
G>A
99153
231449
39.95
2.603e-10
1.03
chr20:19214390
rs6136658
SLC24A3
G>A
3711
9964
39.94
2.62e-10
0.8849
chr15:48392165
rs1834640
-
A>G
8854
22770
39.55
3.201e-10
0.9231
chr2:136407479
rs1446585
R3HDM1
A>G
77544
188854
39.5
3.28e-10
0.9691
chr6:32577973
rs532965
-
T>G
52847
121820
40.07
2.446e-10
1.037
chr6:32607376
rs34250758
HLA-DQA1
G>A
55410
127880
38.4
5.762e-10
1.036
chr6:32581973
rs521539
-
G>A
58935
136160
38.39
5.801e-10
1.035
chr6:32582650
rs3104413
-
C>G
52353
120841
36.56
1.482e-09
1.036
chr6:32577380
rs660895
-
A>G
58861
136106
36.41
1.597e-09
1.034
chr6:396321
rs12203592
IRF4
C>T
60075
138840
36.09
1.888e-09
1.034
chr10:21834536
rs7098100
MLLT10
G>A
93524
217844
35.94
2.038e-09
1.029
chr6:32431147
rs9268877
-
G>A
104458
252243
34.89
3.493e-09
0.9726
chr6:32429594
Affx-28475675
-
G>A
105776
255335
34.82
3.61e-09
0.9727
chr6:32583357
rs6931277
-
A>T
51664
119292
34.79
3.672e-09
1.035
chr6:32439964
rs5026743
-
T>G
105438
254467
34.57
4.108e-09
0.9728
chr10:21824727
rs10828249
MLLT10
G>A
94811
221091
33.5
7.136e-09
1.028
chr6:32546912
rs34252386
HLA-DRB1
A>AG
91353
212663
33.11
8.694e-09
1.029
chr6:32429643
rs9268853
-
T>C
97978
228583
31.91
1.618e-08
1.027
chr6:32634838
rs9274552
HLA-DQB1
C>A
103604
249943
31.31
2.196e-08
0.9739
chr18:35171653
rs12956949
-
A>G
98264
229213
31.09
2.46e-08
1.027
chr7:114015707
rs12705960
FOXP2
A>C
133730
313402
30.73
2.961e-08
1.026
chr20:32484835
rs6057933
-
T>C
14730
36846
30.7
3.019e-08
0.946
chr6:32428115
rs9268835
-
G>A
87681
204353
30.43
3.453e-08
1.027
chr12:104161253
rs77344054
-
C>T
28270
64593
30.36
3.583e-08
1.042
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds ratio
chr4:81184341
rs16998073
-
A>T
79360
56733
29.27
6.281e-08
0.9652
chr4:81164723
rs1458038
-
C>T
78099
55820
29.07
6.991e-08
0.965
chr2:68457573
rs12468533
AC017083.3
T>C
94414
64362
28.54
9.173e-08
1.034
chr2:68435280
rs7572554
AC017083.3
T>C
94299
64304
28.27
1.055e-07
1.034
chr15:91429176
rs7497304
FES
G>T
88182
62897
28.08
1.165e-07
0.9668
chr15:91428521
rs11330240
FES
CT>C
88606
63170
27.43
1.631e-07
0.9672
chr2:68385097
rs2044693
AC017083.3
G>A
97692
66703
26.01
3.403e-07
1.032
chr16:89708224
rs164749
-
T>G
118276
81060
25.47
4.484e-07
1.031
chr15:91404705
rs4932370
-
G>A
91194
64930
25.32
4.863e-07
0.9687
chr4:81157098
rs6848130
-
T>C
74236
53017
25.02
5.667e-07
0.967
chr4:81158221
rs17004846
-
A>G
96895
68933
24.94
5.927e-07
0.9694
chr9:136149399
rs507666
ABO
G>A
49234
35419
24.74
6.554e-07
0.9624
chr9:136149229
rs505922
ABO
T>C
85440
60889
24.52
7.364e-07
0.9687
chr9:136137065
rs687621
ABO
A>G
85709
61026
24.06
9.318e-07
0.969
chr9:136155000
rs635634
-
C>T
48898
35161
23.95
9.869e-07
0.9628
chr6:32359821
rs17577980
-
G>A
18424
13540
23.44
1.291e-06
0.9448
chr16:89702124
rs449882
DPEP1
C>G
117887
80815
23.43
1.297e-06
1.03
chr12:104161253
rs77344054
-
C>T
28270
18866
22.96
1.657e-06
1.049
chr20:55296245
rs6069841
-
A>G
14971
11062
22.7
1.898e-06
0.9404
chr9:136143442
rs612169
ABO
A>G
85841
61094
22.62
1.975e-06
0.97
Associated Diseases
ⓘ
Shared SNP diseases
No shared SNP diseases
ID
Name
Top Correlation
ICD: D125
Sigmoid colon
4/20
ICD: D128
Rectum
4/20
ICD: E114
With neurological complications
2/20
ICD: H330
Retinal detachment with retinal break
2/20
ICD: H334
Traction detachment of retina
1/20
ICD: H360
Diabetic retinopathy
2/20
ICD: I639
Cerebral infarction, unspecified
1/20
ICD: I849
Unspecified haemorrhoids without complication
1/20
ICD: K221
Ulcer of oesophagus
4/20
ICD: K573
Diverticular disease of large intestine without perforation or abscess
4/20
ICD: K579
Diverticular disease of intestine, part unspecified, without perforation or abscess
5/20
ICD: K649
Haemorrhoids, unspecified
2/20
ICD: K921
Melaena
1/20
ICD: K922
Gastro-intestinal haemorrhage, unspecified
1/20
ICD: M189
Arthrosis of first carpometacarpal joint, unspecified
2/20
ICD: M199
Arthrosis, unspecified
4/20
ICD: O16
Unspecified maternal hypertension
2/20
ICD: O209
Haemorrhage in early pregnancy, unspecified
1/20
ICD: O268
Other specified pregnancy-related conditions
4/20
ICD: O420
Premature rupture of membranes, onset of labour within 24 hours
4/20
ICD: O429
Premature rupture of membranes, unspecified
1/20
ICD: O469
Antepartum haemorrhage, unspecified
1/20
ICD: O479
False labour, unspecified
3/20
ICD: O60
Preterm delivery
4/20
ICD: O722
Delayed and secondary postpartum haemorrhage
1/20
ICD: O800
Spontaneous vertex delivery
2/20
ICD: O821
Delivery by emergency Caesarean section
3/20
ICD: R040
Epistaxis
1/20
ICD: R194
Change in bowel habit
2/20
ID
Name
Top Correlation
ICD-10: A408
Other streptococcal septicaemia
0/20
ICD-10: B509
Plasmodium falciparum malaria, unspecified
0/20
ICD-10: C185
Splenic flexure
0/20
ICD-10: C186
Descending colon
0/20
ICD-10: C187
Sigmoid colon
0/20
ICD-10: C19
Malignant neoplasm of rectosigmoid junction
0/20
ICD-10: D124
Descending colon
0/20
ICD-10: D127
Rectosigmoid junction
0/20
ICD-10: D140
Middle ear, nasal cavity and accessory sinuses
0/20
ICD-10: D375
Rectum
0/20
ICD-10: D62
Acute posthaemorrhagic anaemia
0/20
ICD-10: D682
Hereditary deficiency of other clotting factors
0/20
ICD-10: D693
Idiopathic thrombocytopenic purpura
0/20
ICD-10: D759
Disease of blood and blood-forming organs, unspecified
0/20
ICD-10: E104
With neurological complications
0/20
ICD-10: E65
Localised adiposity
0/20
ICD-10: E86
Volume depletion
0/20
ICD-10: E877
Fluid overload
0/20
ICD-10: G458
Other transient cerebral ischaemic attacks and related syndromes
0/20
ICD-10: H119
Disorder of conjunctiva, unspecified
0/20
ICD-10: H179
Corneal scar and opacity, unspecified
0/20
ICD-10: H261
Traumatic cataract
0/20
ICD-10: H333
Retinal breaks without detachment
0/20
ICD-10: H352
Other proliferative retinopathy
0/20
ICD-10: H356
Retinal haemorrhage
0/20
ICD-10: H431
Vitreous haemorrhage
0/20
ICD-10: H438
Other disorders of vitreous body
0/20
ICD-10: I601
Subarachnoid haemorrhage from middle cerebral artery
0/20
ICD-10: I602
Subarachnoid haemorrhage from anterior communicating artery
0/20
ICD-10: I603
Subarachnoid haemorrhage from posterior communicating artery
0/20
ICD-10: I609
Subarachnoid haemorrhage, unspecified
0/20
ICD-10: I611
Intracerebral haemorrhage in hemisphere, cortical
0/20
ICD-10: I615
Intracerebral haemorrhage, intraventricular
0/20
ICD-10: I619
Intracerebral haemorrhage, unspecified
0/20
ICD-10: I620
Subdural haemorrhage (acute) (nontraumatic)
0/20
ICD-10: I629
Intracranial haemorrhage (nontraumatic), unspecified
0/20
ICD-10: I632
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0/20
ICD-10: I633
Cerebral infarction due to thrombosis of cerebral arteries
0/20
ICD-10: I634
Cerebral infarction due to embolism of cerebral arteries
0/20
ICD-10: I635
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0/20
ICD-10: I638
Other cerebral infarction
0/20
ICD-10: I64
Stroke, not specified as haemorrhage or infarction
0/20
ICD-10: I671
Cerebral aneurysm, nonruptured
0/20
ICD-10: I690
Sequelae of subarachnoid haemorrhage
0/20
ICD-10: I691
Sequelae of intracerebral haemorrhage
0/20
ICD-10: I694
Sequelae of stroke, not specified as haemorrhage or infarction
0/20
ICD-10: I712
Thoracic aortic aneurysm, without mention of rupture
0/20
ICD-10: I719
Aortic aneurysm of unspecified site, without mention of rupture
0/20
ICD-10: I720
Aneurysm of carotid artery
0/20
ICD-10: I728
Aneurysm of other specified arteries
0/20
ICD-10: I780
Hereditary haemorrhagic telangiectasia
0/20
ICD-10: I842
Internal haemorrhoids without complication
0/20
ICD-10: I845
External haemorrhoids without complication
0/20
ICD-10: I846
Residual haemorrhoidal skin tags
0/20
ICD-10: I859
Oesophageal varices without bleeding
0/20
ICD-10: I864
Gastric varices
0/20
ICD-10: I952
Hypotension due to drugs
0/20
ICD-10: J80
Adult respiratory distress syndrome
0/20
ICD-10: J960
Acute respiratory failure
0/20
ICD-10: K051
Chronic gingivitis
0/20
ICD-10: K056
Periodontal disease, unspecified
0/20
ICD-10: K081
Loss of teeth due to accident, extraction or local periodontal disease
0/20
ICD-10: K136
Irritative hyperplasia of oral mucosa
0/20
ICD-10: K226
Gastro-oesophageal laceration-haemorrhage syndrome
0/20
ICD-10: K290
Acute haemorrhagic gastritis
0/20
ICD-10: K292
Alcoholic gastritis
0/20
ICD-10: K512
Ulcerative (chronic) proctitis
0/20
ICD-10: K513
Ulcerative (chronic) rectosigmoiditis
0/20
ICD-10: K552
Angiodysplasia of colon
0/20
ICD-10: K571
Diverticular disease of small intestine without perforation or abscess
0/20
ICD-10: K572
Diverticular disease of large intestine with perforation and abscess
0/20
ICD-10: K578
Diverticular disease of intestine, part unspecified, with perforation and abscess
0/20
ICD-10: K600
Acute anal fissure
0/20
ICD-10: K627
Radiation proctitis
0/20
ICD-10: K640
First degree haemorrhoids
0/20
ICD-10: K641
Second degree haemorrhoids
0/20
ICD-10: K642
Third degree haemorrhoids
0/20
ICD-10: K644
Residual haemorrhoidal skin tags
0/20
ICD-10: K648
Other specified haemorrhoids
0/20
ICD-10: K920
Haematemesis
0/20
ICD-10: L500
Allergic urticaria
0/20
ICD-10: L959
Vasculitis limited to skin, unspecified
0/20
ICD-10: M0730
Other psoriatic arthropathies (Multiple sites)
0/20
ICD-10: M0739
Other psoriatic arthropathies (Site unspecified)
0/20
ICD-10: M150
Primary generalised (osteo)arthrosis
0/20
ICD-10: M180
Primary arthrosis of first carpometacarpal joints, bilateral
0/20
ICD-10: M181
Other primary arthrosis of first carpometacarpal joint
0/20
ICD-10: M190
Primary arthrosis of other joints
0/20
ICD-10: M234
Loose body in knee
0/20
ICD-10: M254
Effusion of joint
0/20
ICD-10: M255
Pain in joint
0/20
ICD-10: M258
Other specified joint disorders
0/20
ICD-10: M2596
Joint disorder, unspecified (Lower leg)
0/20
ICD-10: M313
Wegener's granulomatosis
0/20
ICD-10: M359
Systemic involvement of connective tissue, unspecified
0/20
ICD-10: M704
Prepatellar bursitis
0/20
ICD-10: M960
Pseudarthrosis after fusion or arthrodesis
0/20
ICD-10: N085
Glomerular disorders in systemic connective tissue disorders
0/20
ICD-10: N321
Vesicointestinal fistula
0/20
ICD-10: N831
Corpus luteum cyst
0/20
ICD-10: N907
Vulvar cyst
0/20
ICD-10: N923
Ovulation bleeding
0/20
ICD-10: O200
Threatened abortion
0/20
ICD-10: O421
Premature rupture of membranes, onset of labour after 24 hours
0/20
ICD-10: O440
Placenta praevia specified as without haemorrhage
0/20
ICD-10: O441
Placenta praevia with haemorrhage
0/20
ICD-10: O470
False labour before 37 completed weeks of gestation
0/20
ICD-10: O471
False labour at or after 37 completed weeks of gestation
0/20
ICD-10: O639
Long labour, unspecified
0/20
ICD-10: O640
Obstructed labour due to incomplete rotation of foetal head
0/20
ICD-10: O641
Obstructed labour due to breech presentation
0/20
ICD-10: O660
Obstructed labour due to shoulder dystocia
0/20
ICD-10: O679
Intrapartum haemorrhage, unspecified
0/20
ICD-10: O730
Retained placenta, without haemorrhage
0/20
ICD-10: O756
Delayed delivery after spontaneous or unspecified rupture of membranes
0/20
ICD-10: O758
Other specified complications of labour and delivery
0/20
ICD-10: Q273
Peripheral arteriovenous malformation
0/20
ICD-10: Q430
Meckel's diverticulum
0/20
ICD-10: R042
Haemoptysis
0/20
ICD-10: R090
Asphyxia
0/20
ICD-10: R233
Spontaneous ecchymoses
0/20
ICD-10: R944
Abnormal results of kidney function studies
0/20