Abnormal renal cortex morphology

0011035

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

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Interactive Plot

Statistics

Case	Control
10871	449323

Phenotype Definition

An abnormality of the cortex of the kidney. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951116	rs35397	SLC45A2	T>G	1884	88224	28.51	9.335e-08	0.8783
chr24:14902414	rs20321	USP9Y	G>A	313	8945	26.91	2.136e-07	1.357
chr15:80985287	rs11629662	ABHD17C	A>G	3388	129838	25.94	3.524e-07	1.101
chr6:396321	rs12203592	IRF4	C>T	5036	196169	25.62	4.155e-07	1.085
chr5:33958959	rs28777	SLC45A2	A>C	1165	55827	24.17	8.832e-07	0.8614
chr7:78169182	rs10243724	MAGI2	G>C	306	16842	24.17	8.801e-07	0.7523
chr17:65408079	rs117216304	PITPNC1	G>A	388	12624	23.69	1.134e-06	1.287
chr5:33951693	rs16891982	SLC45A2	G>C	1391	65667	23.35	1.35e-06	0.8737
chr11:104895327	rs555301	-	C>G	2552	96927	23.19	1.469e-06	1.108
chr12:9407639	rs75641881	-	C>T	2636	119622	22.13	2.548e-06	0.9062
chr15:48426484	rs1426654	SLC24A5	A>G	530	26996	22.01	2.719e-06	0.8124
chr15:69891096	rs72743944	-	A>C	550	18769	21.47	3.598e-06	1.225
chr17:10148724	rs4791955	-	T>C	5395	212271	21.34	3.845e-06	1.076
chr19:53408165	rs7258315	ZNF888	G>C	4933	217558	20.92	4.791e-06	0.9283
chr21:24271200	rs244138	-	A>G	6547	286815	20.89	4.864e-06	0.9337
chr4:171807535	rs7673440	-	A>C	3713	143571	20.85	4.969e-06	1.087
chr6:147680176	rs117319597	STXBP5	C>T	350	11395	20.77	5.178e-06	1.282
chr3:123419733	rs3732486	MYLK	A>G	536	27137	20.68	5.437e-06	0.8184
chr5:61150082	rs114641859	-	C>T	469	15794	20.68	5.441e-06	1.24
chr4:73051488	rs12642225	-	C>G	589	29515	20.65	5.52e-06	0.8259
chr24:14902414	rs20321	USP9Y	G>A	309	8845	25.41	4.646e-07	1.349
chr17:65408079	rs117216304	PITPNC1	G>A	376	12211	22.1	2.586e-06	1.281
chr11:134177205	rs12272129	GLB1L3	G>T	4748	184436	21.74	3.122e-06	1.081
chr15:80985287	rs11629662	ABHD17C	A>G	3331	127681	21.58	3.389e-06	1.093
chr4:118093137	rs10433903	-	T>C	7804	309051	21.31	3.897e-06	1.068
chr4:171807535	rs7673440	-	A>C	3573	137211	20.52	5.912e-06	1.088
chr6:147680176	rs117319597	STXBP5	C>T	346	11212	20.22	6.916e-06	1.28
chr3:72683651	rs10049353	-	T>C	7033	277806	20.21	6.952e-06	1.068
chr15:69558040	rs11636090	GLCE	T>C	968	34743	19.85	8.361e-06	1.16
chr6:396321	rs12203592	IRF4	C>T	4972	193943	19.67	9.218e-06	1.075
chr2:40543129	rs62150814	SLC8A1	T>A	475	24023	19.56	9.727e-06	0.8131
chr7:9223595	rs7796895	-	A>G	6873	296658	19.52	9.97e-06	0.9368
chr20:4139254	rs117910398	SMOX	A>G	448	15035	19.27	1.134e-05	1.236
chr15:69891096	rs72743944	-	A>C	530	18111	19.04	1.278e-05	1.215
chr3:72674925	rs7637028	-	A>G	6222	245154	19.01	1.297e-05	1.069
chr16:58508843	rs56379581	NDRG4	C>G	706	34304	18.87	1.399e-05	0.8456
chr9:32343783	rs17215431	-	G>A	1782	66642	18.73	1.508e-05	1.114
chr6:168670236	rs9355061	-	G>T	379	12554	18.37	1.822e-05	1.252
chr11:104895327	rs555301	-	C>G	2455	93429	18.28	1.909e-05	1.097
chr14:32493840	rs74678887	-	G>A	408	13643	18.21	1.983e-05	1.241

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr7:28557996	rs73299166	CREB5	C>T	1723	4507	24.8	6.365e-07	0.8634
chr4:149496448	rs35506581	-	G>A	1930	3874	23.27	1.41e-06	1.15
chr17:10148724	rs4791955	-	T>C	5395	11503	23.1	1.537e-06	1.095
chr17:75075459	rs7224327	-	G>A	8148	17719	23.06	1.57e-06	1.083
chr4:149398316	rs71616586	-	G>A	1536	3041	22.77	1.829e-06	1.167
chr4:171807535	rs7673440	-	A>C	3713	7766	22.42	2.187e-06	1.109
chr5:33951116	rs35397	SLC45A2	T>G	1884	4852	21.6	3.357e-06	0.8765
chr18:73191145	rs35957621	-	G>A	941	2540	20.74	5.254e-06	0.8373
chr2:40543129	rs62150814	SLC8A1	T>A	484	1397	20.04	7.582e-06	0.788
chr10:18442106	rs11012827	CACNB2	A>G	732	1369	19.94	7.998e-06	1.23
chr14:104188127	rs35311561	ZFYVE21	G>A	6550	14135	19.6	9.548e-06	1.081
chr5:33951693	rs16891982	SLC45A2	G>C	1391	3632	19.09	1.245e-05	0.8674
chr2:217711655	rs1179708	-	T>G	8475	20254	18.99	1.314e-05	0.9311
chr4:118093137	rs10433903	-	T>C	8229	17944	18.99	1.312e-05	1.075
chr5:33958959	rs28777	SLC45A2	A>C	1165	3078	18.81	1.446e-05	0.858
chr1:234564951	rs12135427	TARBP1	A>T	350	600	18.61	1.605e-05	1.338
chr12:9407639	rs75641881	-	C>T	2636	6614	18.56	1.648e-05	0.8997
chr14:32493840	rs74678887	-	G>A	409	718	18.54	1.66e-05	1.308
chr17:65408079	rs117216304	PITPNC1	G>A	388	677	18.53	1.669e-05	1.317
chr15:69558040	rs11636090	GLCE	T>C	997	1937	18.45	1.746e-05	1.186
chr4:149496448	rs35506581	-	G>A	1909	3802	23.17	1.487e-06	1.151
chr4:118093137	rs10433903	-	T>C	7804	16789	22.88	1.724e-06	1.085
chr17:75075459	rs7224327	-	G>A	7847	16931	22.78	1.816e-06	1.085
chr4:149398316	rs71616586	-	G>A	1517	2988	21.84	2.964e-06	1.165
chr7:28557996	rs73299166	CREB5	C>T	1457	3796	21.69	3.209e-06	0.8618
chr2:40543129	rs62150814	SLC8A1	T>A	475	1376	21.63	3.298e-06	0.7789
chr4:171807535	rs7673440	-	A>C	3573	7431	21.22	4.095e-06	1.108
chr10:18442106	rs11012827	CACNB2	A>G	691	1267	21.06	4.448e-06	1.246
chr2:217711655	rs1179708	-	T>G	8027	19109	21.04	4.502e-06	0.9257
chr15:69558040	rs11636090	GLCE	T>C	968	1845	20.49	6.009e-06	1.201
chr6:125122128	rs6924401	NKAIN2	A>G	4762	11553	19.22	1.164e-05	0.9179
chr3:144732045	rs76859420	-	G>A	1009	2672	18.66	1.56e-05	0.8492
chr8:63934532	rs117061297	GGH	C>T	266	815	18.55	1.658e-05	0.7371
chr8:63596549	rs117892667	NKAIN3	T>C	240	745	18.23	1.96e-05	0.728
chr2:88820471	rs62159797	-	G>A	3678	8992	18.12	2.069e-05	0.9124
chr17:65408079	rs117216304	PITPNC1	G>A	376	651	17.98	2.237e-05	1.318
chr16:87218204	rs74037595	C16orf95	G>T	491	1387	17.96	2.258e-05	0.7987
chr17:10148724	rs4791955	-	T>C	5121	10911	17.92	2.298e-05	1.085
chr2:40699589	rs17533866	SLC8A1	C>A	1123	2939	17.91	2.321e-05	0.8586
chr11:20040206	rs4525210	NAV2	T>C	1897	3843	17.86	2.381e-05	1.132

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: C440	Skin of lip	3/20
ICD: H530	Amblyopia ex anopsia	3/20
ICD: R296	Tendency to fall, not elsewhere classified	6/20
ICD: W199	Unspecified place	3/20

ID	Name	Top Correlation
ICD-10: A490	Staphylococcal infection, unspecified	0/20
ICD-10: D230	Skin of lip	0/20
ICD-10: H549	Unspecified visual impairment (binocular)	0/20
ICD-10: M313	Wegener's granulomatosis	0/20
ICD-10: N029	Unspecified	0/20
ICD-10: N039	Unspecified	0/20
ICD-10: N049	Unspecified	0/20
ICD-10: N059	Unspecified	0/20
ICD-10: N119	Chronic tubulo-interstitial nephritis, unspecified	0/20
ICD-10: N138	Other obstructive and reflux uropathy	0/20
ICD-10: N139	Obstructive and reflux uropathy, unspecified	0/20
ICD-10: N26	Unspecified contracted kidney	0/20
ICD-10: N399	Disorder of urinary system, unspecified	0/20
ICD-10: O622	Other uterine inertia	0/20
ICD-10: Q600	Renal agenesis, unilateral	0/20
ICD-10: R34	Anuria and oliguria	0/20
ICD-10: R80	Isolated proteinuria	0/20

Abnormal renal cortex morphology

0011035

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ