Respiratory tract infection

0011947

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

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Sex Split

Interactive Plot

Statistics

Case	Control
52697	407497

Phenotype Definition

An infection of the upper or lower respiratory tract. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr6:396321	rs12203592	IRF4	C>T	23988	177217	54.57	1.497e-13	1.059
chr2:135837906	rs7570971	RAB3GAP1	C>A	33738	269835	48.94	2.646e-12	0.9527
chr2:136407479	rs1446585	R3HDM1	A>G	29534	236864	46.81	7.81e-12	0.9519
chr2:173168867	rs3934991	-	G>A	2245	20129	44.97	1.999e-11	0.8602
chr6:170242949	rs9396958	-	T>C	1577	14537	44.26	2.872e-11	0.8374
chr4:100239319	rs1229984	ADH1B	C>T	3129	27347	42.96	5.573e-11	0.8821
chr15:78907656	rs6495308	CHRNA3	T>C	25771	206654	38.93	4.386e-10	0.9541
chr2:136825272	rs932206	-	T>C	41681	330644	37.43	9.455e-10	0.9605
chr18:77563334	rs11665567	-	G>A	23755	177010	37.1	1.123e-09	1.049
chr2:135911422	Affx-17900027	RAB3GAP1	T>C	26725	213881	35.91	2.062e-09	0.9564
chr14:106053975	rs72713340	-	G>A	1914	17070	35.58	2.447e-09	0.8651
chr15:78783277	rs11858836	IREB2	G>A	35465	266930	34.35	4.595e-09	1.041
chr6:32210799	rs419132	-	A>G	25385	203194	34.32	4.671e-09	0.9566
chr6:421281	rs62389423	-	G>A	19458	144578	33.75	6.27e-09	1.05
chr15:78863472	rs667282	CHRNA5	T>C	25513	204083	33.42	7.432e-09	0.9572
chr15:78896547	rs938682	CHRNA3	A>G	25633	204992	33.26	8.066e-09	0.9574
chr5:177854281	rs114214071	COL23A1	A>G	3298	28304	33.13	8.619e-09	0.8981
chr15:78873119	rs569207	CHRNA5	C>T	25545	204294	32.89	9.764e-09	0.9576
chr16:11366258	rs59124406	RMI2	G>A	1580	14209	32.75	1.046e-08	0.8584
chr15:78891627	rs12910984	CHRNA3	A>G	25729	205740	32.71	1.069e-08	0.9578
chr6:396321	rs12203592	IRF4	C>T	23698	175217	52.15	5.151e-13	1.059
chr2:135837906	rs7570971	RAB3GAP1	C>A	28711	229175	36.46	1.557e-09	0.9566
chr2:136407479	rs1446585	R3HDM1	A>G	24701	197759	34.86	3.54e-09	0.9555
chr6:32210799	rs419132	-	A>G	22156	177756	34.03	5.431e-09	0.9543
chr6:421281	rs62389423	-	G>A	19206	142659	33.44	7.352e-09	1.05
chr15:78741384	rs2656074	IREB2	C>T	22107	177138	32.32	1.308e-08	0.9554
chr6:32607376	rs34250758	HLA-DQA1	G>A	21682	161608	32.17	1.415e-08	1.047
chr15:78863472	rs667282	CHRNA5	T>C	23260	186191	32.13	1.444e-08	0.9563
chr15:78873119	rs569207	CHRNA5	C>T	23306	186517	31.7	1.798e-08	0.9566
chr15:78907656	rs6495308	CHRNA3	T>C	23392	187140	31.33	2.177e-08	0.9569
chr15:78754000	rs1964678	IREB2	G>A	39417	312036	30.95	2.646e-08	0.9631
chr15:78896547	rs938682	CHRNA3	A>G	23391	187053	30.81	2.85e-08	0.9573
chr15:78891627	rs12910984	CHRNA3	A>G	23377	186971	30.48	3.368e-08	0.9575
chr18:77563334	rs11665567	-	G>A	22730	169776	30.44	3.443e-08	1.045
chr6:32209027	rs382259	-	T>C	21217	170014	30.4	3.511e-08	0.956
chr15:78783277	rs11858836	IREB2	G>A	34375	258991	30.18	3.931e-08	1.039
chr15:78789488	rs13180	IREB2	T>C	39642	313618	29.64	5.196e-08	0.9639
chr15:78774271	rs8042238	IREB2	T>C	39630	313531	29.36	5.996e-08	0.964
chr6:475489	rs12210050	-	C>T	21950	164046	27.8	1.347e-07	1.043
chr2:136825272	rs932206	-	T>C	36647	290124	27.77	1.365e-07	0.9643

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr14:42597168	rs1825713	-	A>G	5176	3939	23.92	1.003e-06	1.112
chr2:186554772	rs116131645	-	A>G	2262	2197	23.46	1.273e-06	0.8636
chr15:78741384	rs2656074	IREB2	C>T	22107	19399	22.93	1.678e-06	0.9482
chr14:57489586	rs7143862	-	G>A	20891	18365	22.41	2.204e-06	0.9477
chr22:49077114	rs7511071	TAFA5	G>A	12714	10094	21.96	2.777e-06	1.069
chr6:92889890	rs12212424	-	A>C	28010	24420	21.54	3.471e-06	0.9535
chr13:99635611	rs17785077	DOCK9	G>A	11143	8815	21.19	4.149e-06	1.072
chr6:65382136	rs12203072	EYS	T>C	42172	34619	21.08	4.406e-06	1.044
chr16:6558638	rs79866383	RBFOX1	T>C	1975	1422	20.84	4.984e-06	1.174
chr1:247234754	rs78805933	ZNF670-ZNF695	A>G	2991	2222	20.79	5.112e-06	1.138
chr14:75750105	Affx-35929150	-	A>G	16305	13077	20.41	6.254e-06	1.059
chr1:87743989	rs4655843	-	C>T	39279	32189	20.07	7.485e-06	1.043
chr2:220567392	rs2194776	-	C>T	2812	2666	19.93	8.018e-06	0.8848
chr1:6871756	rs17441010	CAMTA1	A>G	4831	4452	19.81	8.56e-06	0.9096
chr4:156601201	rs13114009	GUCY1A1	A>G	29143	23736	19.47	1.019e-05	1.046
chr1:909238	rs3829740	PLEKHN1	C>G	45862	37737	19.46	1.03e-05	1.041
chr9:79385790	rs78791104	PRUNE2	T>C	3313	2488	19.23	1.157e-05	1.125
chr1:31073453	rs61766955	-	A>G	6205	5650	19.22	1.165e-05	0.9202
chr6:65363281	rs6454948	EYS	T>C	41847	34373	19.1	1.243e-05	1.042
chr15:84661145	rs62027818	ADAMTSL3	T>C	22702	19824	18.98	1.324e-05	0.9532

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: J181	Lobar pneumonia, unspecified	4/20
ICD: J189	Pneumonia, unspecified	2/20
ICD: J22	Unspecified acute lower respiratory infection	1/20
ICD: J439	Emphysema, unspecified	1/20
ICD: J441	Chronic obstructive pulmonary disease with acute exacerbation, unspecified	1/20
ICD: J448	Other specified chronic obstructive pulmonary disease	2/20

ID	Name	Top Correlation
ICD-10: A045	Campylobacter enteritis	0/20
ICD-10: A048	Other specified bacterial intestinal infections	0/20
ICD-10: A491	Streptococcal infection, unspecified	0/20
ICD-10: B348	Other viral infections of unspecified site	0/20
ICD-10: B349	Viral infection, unspecified	0/20
ICD-10: B953	Streptococcus pneumoniae as the cause of diseases classified to other chapters	0/20
ICD-10: B961	Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0/20
ICD-10: C099	Tonsil, unspecified	0/20
ICD-10: C180	Caecum	0/20
ICD-10: C880	Waldenstrom's macroglobulinaemia	0/20
ICD-10: D120	Caecum	0/20
ICD-10: D801	Nonfamilial hypogammaglobulinaemia	0/20
ICD-10: G553	Nerve root and plexus compressions in other dorsopathies	0/20
ICD-10: H654	Other chronic nonsuppurative otitis media	0/20
ICD-10: J019	Acute sinusitis, unspecified	0/20
ICD-10: J029	Acute pharyngitis, unspecified	0/20
ICD-10: J039	Acute tonsillitis, unspecified	0/20
ICD-10: J040	Acute laryngitis	0/20
ICD-10: J069	Acute upper respiratory infection, unspecified	0/20
ICD-10: J100	Influenza with pneumonia, influenza virus identified	0/20
ICD-10: J13	Pneumonia due to Streptococcus pneumoniae	0/20
ICD-10: J14	Pneumonia due to Haemophilus influenzae	0/20
ICD-10: J150	Pneumonia due to Klebsiella pneumoniae	0/20
ICD-10: J151	Pneumonia due to Pseudomonas	0/20
ICD-10: J152	Pneumonia due to staphylococcus	0/20
ICD-10: J154	Pneumonia due to other streptococci	0/20
ICD-10: J180	Bronchopneumonia, unspecified	0/20
ICD-10: J209	Acute bronchitis, unspecified	0/20
ICD-10: J312	Chronic pharyngitis	0/20
ICD-10: J328	Other chronic sinusitis	0/20
ICD-10: J350	Chronic tonsillitis	0/20
ICD-10: J36	Peritonsillar abscess	0/20
ICD-10: J398	Other specified diseases of upper respiratory tract	0/20
ICD-10: J40	Bronchitis, not specified as acute or chronic	0/20
ICD-10: J42	Unspecified chronic bronchitis	0/20
ICD-10: J432	Centrilobular emphysema	0/20
ICD-10: J440	Chronic obstructive pulmonary disease with acute lower respiratory infection	0/20
ICD-10: J449	Chronic obstructive pulmonary disease, unspecified	0/20
ICD-10: J61	Pneumoconiosis due to asbestos and other mineral fibres	0/20
ICD-10: J690	Pneumonitis due to food and vomit	0/20
ICD-10: J950	Tracheostomy malfunction	0/20
ICD-10: J958	Other postprocedural respiratory disorders	0/20
ICD-10: J989	Respiratory disorder, unspecified	0/20
ICD-10: K073	Anomalies of tooth position	0/20
ICD-10: K292	Alcoholic gastritis	0/20
ICD-10: K528	Other specified non-infective gastro-enteritis and colitis	0/20
ICD-10: L988	Other specified disorders of skin and subcutaneous tissue	0/20
ICD-10: M500	Cervical disk disorder with myelopathy	0/20
ICD-10: M549	Dorsalgia, unspecified	0/20
ICD-10: N398	Other specified disorders of urinary system	0/20
ICD-10: N760	Acute vaginitis	0/20
ICD-10: R062	Wheezing	0/20
ICD-10: R070	Pain in throat	0/20
ICD-10: R093	Abnormal sputum	0/20
ICD-10: R845	Abnormal microbiological findings	0/20
ICD-10: T598	Other specified gases, fumes and vapours	0/20

Respiratory tract infection

0011947

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ