Intracranial epidermoid cyst


Normal Case/Contol

GWAS of 0012096

Sibling Case/Control

No sibling GWAS available 0012096


Case Control
2819 457375

Phenotype Definition

A congenital inclusion cysts that arises from ectodermal cells that normally form skin cells being left behind in the nervous system during development. [HPO:probinson, PMID:16714456]

Phenotype Comment

See Figure 8 in PMID:16714456. Epidermoid cysts arise from ectodermal inclusion during neural tube closure in the 3rd-5th week of embryogenesis. The microscopic cyst lining consists of stratified squamous epithelium supported by an outer layer of collagenous connective tissue. Cystic contents usually include debris, keratin, water, and cholesterol laid down in a lamellar fashion. Epidermoid cysts do not contain dermal appendages.

Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: L720 Epidermal cyst 19/20