Statistics
| Case | Control |
|---|---|
| 5326 | 454868 |
Phenotype Definition
A sudden, irresistible need to have a bowel movement. [UToronto:htrang]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr16:7309339 | rs17143097 | RBFOX1 | T>C | 238 | 14292 | 29.28 | 6.255e-08 | 1.427 |
| chr6:154237937 | rs4870255 | - | G>T | 1382 | 133556 | 25.55 | 4.301e-07 | 0.8644 |
| chr19:53895955 | rs12983284 | ZNF765 | T>C | 5790 | 472284 | 23.12 | 1.521e-06 | 1.095 |
| chr1:57602383 | rs563921 | DAB1 | T>C | 2322 | 180741 | 23.03 | 1.593e-06 | 1.119 |
| chr1:61250591 | rs34655839 | - | A>G | 1677 | 128409 | 21.96 | 2.78e-06 | 1.133 |
| chr9:112702724 | rs73539445 | PALM2AKAP2 | A>G | 916 | 67171 | 21.88 | 2.902e-06 | 1.176 |
| chr19:53888813 | rs12983975 | ZNF525 | A>G | 5843 | 476806 | 21.72 | 3.158e-06 | 1.092 |
| chr13:98038846 | rs10459305 | MBNL2 | G>A | 108 | 14308 | 21.63 | 3.303e-06 | 0.6391 |
| chr9:78199135 | rs79794811 | - | T>G | 206 | 12715 | 21.47 | 3.595e-06 | 1.387 |
| chr8:2020827 | rs2294059 | MYOM2 | G>C | 4821 | 431922 | 21.07 | 4.428e-06 | 0.9159 |
| chr18:55747303 | rs55784553 | NEDD4L | C>T | 187 | 11463 | 20.31 | 6.573e-06 | 1.396 |
| chr6:26363755 | rs9358934 | - | G>C | 1291 | 123712 | 20.24 | 6.824e-06 | 0.8749 |
| chr9:14809826 | rs1389738 | FREM1 | T>C | 1373 | 104176 | 20.22 | 6.899e-06 | 1.139 |
| chr1:156247665 | rs114416960 | SMG5 | C>T | 315 | 20941 | 19.78 | 8.699e-06 | 1.291 |
| chr6:26368279 | rs72841509 | BTN3A2 | G>A | 1298 | 123944 | 19.23 | 1.157e-05 | 0.8781 |
| chr5:114521710 | rs4041 | - | C>A | 2368 | 185528 | 19.19 | 1.185e-05 | 1.108 |
| chr6:26404374 | rs3799378 | BTN3A1 | A>G | 2453 | 225762 | 19.04 | 1.281e-05 | 0.9047 |
| chr11:11806206 | rs17375799 | - | T>C | 1536 | 117929 | 18.95 | 1.34e-05 | 1.128 |
| chr5:50478828 | rs4373244 | - | G>T | 4126 | 332717 | 18.92 | 1.362e-05 | 1.089 |
| chr12:118186488 | rs603755 | KSR2 | C>T | 1832 | 142184 | 18.83 | 1.427e-05 | 1.118 |
| chr6:154237937 | rs4870255 | - | G>T | 1279 | 124335 | 24.78 | 6.424e-07 | 0.8615 |
| chr9:78199135 | rs79794811 | - | T>G | 203 | 12352 | 23.48 | 1.263e-06 | 1.411 |
| chr1:61250591 | rs34655839 | - | A>G | 1618 | 123630 | 23.32 | 1.375e-06 | 1.14 |
| chr2:185894256 | rs114303014 | - | A>T | 261 | 16696 | 22.07 | 2.624e-06 | 1.344 |
| chr7:7804891 | rs17137468 | UMAD1 | A>G | 744 | 75015 | 21.95 | 2.798e-06 | 0.8363 |
| chr1:61224069 | rs4915708 | - | T>G | 1714 | 132039 | 21.5 | 3.543e-06 | 1.131 |
| chr19:53895955 | rs12983284 | ZNF765 | T>C | 5356 | 437742 | 21.35 | 3.832e-06 | 1.094 |
| chr5:114521710 | rs4041 | - | C>A | 2307 | 180989 | 20.5 | 5.972e-06 | 1.114 |
| chr1:57602383 | rs563921 | DAB1 | T>C | 2015 | 156974 | 20.34 | 6.469e-06 | 1.119 |
| chr11:11806206 | rs17375799 | - | T>C | 1434 | 109643 | 20.12 | 7.286e-06 | 1.137 |
| chr17:43901665 | rs80067508 | LINC02210-CRHR1 | T>C | 615 | 44041 | 19.96 | 7.913e-06 | 1.205 |
| chr19:15112239 | rs10423303 | SLC1A6 | G>A | 805 | 59016 | 19.92 | 8.071e-06 | 1.179 |
| chr3:86063320 | rs73134199 | CADM2 | T>C | 1013 | 75756 | 19.72 | 8.959e-06 | 1.159 |
| chr1:156247665 | rs114416960 | SMG5 | C>T | 310 | 20640 | 19.7 | 9.055e-06 | 1.293 |
| chr7:67715697 | rs117105802 | - | G>T | 188 | 11637 | 19.57 | 9.677e-06 | 1.386 |
| chr8:34415528 | rs4291266 | - | A>G | 1659 | 128195 | 19.35 | 1.088e-05 | 1.126 |
| chr6:68595171 | rs9454346 | - | T>C | 3300 | 263956 | 19.31 | 1.111e-05 | 1.097 |
| chr19:53888813 | rs12983975 | ZNF525 | A>G | 5362 | 438999 | 18.9 | 1.378e-05 | 1.089 |
| chr5:37735573 | rs16903709 | WDR70 | A>G | 663 | 66536 | 18.55 | 1.658e-05 | 0.8408 |
| chr8:2020827 | rs2294059 | MYOM2 | G>C | 4594 | 411898 | 18.45 | 1.742e-05 | 0.9188 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:154237937 | rs4870255 | - | G>T | 1279 | 12654 | 23.96 | 9.832e-07 | 0.858 |
| chr1:61250591 | rs34655839 | - | A>G | 1618 | 12470 | 22.94 | 1.675e-06 | 1.147 |
| chr10:37256635 | rs2488747 | - | T>C | 3694 | 29914 | 21.97 | 2.766e-06 | 1.106 |
| chr1:57602383 | rs563921 | DAB1 | T>C | 2015 | 15804 | 21.16 | 4.232e-06 | 1.128 |
| chr8:34415528 | rs4291266 | - | A>G | 1659 | 12871 | 20.87 | 4.903e-06 | 1.138 |
| chr19:53895955 | rs12983284 | ZNF765 | T>C | 5356 | 44338 | 20.36 | 6.415e-06 | 1.097 |
| chr1:61224069 | rs4915708 | - | T>G | 1714 | 13372 | 19.77 | 8.749e-06 | 1.132 |
| chr7:67715697 | rs117105802 | - | G>T | 188 | 1153 | 19.68 | 9.137e-06 | 1.419 |
| chr6:68595171 | rs9454346 | - | T>C | 3300 | 26667 | 19.31 | 1.111e-05 | 1.102 |
| chr3:86063320 | rs73134199 | CADM2 | T>C | 1013 | 7636 | 19.29 | 1.121e-05 | 1.167 |
| chr5:62238258 | rs17476228 | - | C>T | 1592 | 15335 | 19.19 | 1.186e-05 | 0.8824 |
| chr11:11806206 | rs17375799 | - | T>C | 1434 | 11080 | 19.19 | 1.181e-05 | 1.141 |
| chr1:57615514 | rs17115220 | DAB1 | G>A | 1184 | 9032 | 18.72 | 1.514e-05 | 1.152 |
| chr1:57599216 | rs546020 | DAB1 | T>C | 1743 | 13652 | 18.4 | 1.788e-05 | 1.127 |
| chr18:21568367 | rs6508073 | - | C>T | 1768 | 16826 | 18.4 | 1.795e-05 | 0.889 |
| chr7:128492817 | rs117653869 | FLNC | G>A | 76 | 1084 | 18.29 | 1.9e-05 | 0.6041 |
| chr20:7139241 | rs73598224 | - | A>G | 266 | 1747 | 18.27 | 1.921e-05 | 1.328 |
| chr7:128435403 | rs117651959 | CCDC136 | A>G | 93 | 1265 | 18.21 | 1.975e-05 | 0.6334 |
| chr10:9217032 | rs1149953 | - | C>A | 4217 | 38580 | 18.15 | 2.045e-05 | 0.9147 |
| chr19:53888813 | rs12983975 | ZNF525 | A>G | 5362 | 44467 | 17.79 | 2.469e-05 | 1.091 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|