Statistics
| Case | Control |
|---|---|
| 332 | 459862 |
Phenotype Definition
Tumor (An abnormal mass of tissue resulting from abnormally dividing cells) of the nasal cavity. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:92712489 | rs79102072 | - | G>A | 37 | 21625 | 29.55 | 5.44e-08 | 2.433 |
| chr13:100607344 | rs80169367 | - | G>T | 36 | 21155 | 28.32 | 1.026e-07 | 2.417 |
| chr10:15415828 | rs77079513 | - | T>C | 22 | 11048 | 24.73 | 6.585e-07 | 2.811 |
| chr1:27332637 | rs151266984 | TENT5B | T>G | 24 | 12562 | 24.67 | 6.804e-07 | 2.695 |
| chr10:15343723 | rs57306636 | FAM171A1 | A>G | 271 | 289744 | 24.57 | 7.164e-07 | 1.464 |
| chr1:207578564 | rs56310041 | - | C>T | 22 | 11056 | 24.53 | 7.312e-07 | 2.795 |
| chr20:4210613 | rs118181669 | ADRA1D | C>T | 23 | 12177 | 22.97 | 1.647e-06 | 2.658 |
| chr15:78424369 | rs72732571 | IDH3A | A>C | 24 | 13034 | 22.7 | 1.897e-06 | 2.595 |
| chr3:27953384 | rs114195666 | - | T>C | 38 | 25195 | 21.81 | 3.003e-06 | 2.14 |
| chr9:111562833 | rs117972024 | - | A>G | 28 | 16515 | 21.67 | 3.239e-06 | 2.388 |
| chr10:130413057 | rs78132018 | - | C>T | 141 | 135808 | 21.02 | 4.54e-06 | 1.535 |
| chr3:19693610 | rs75024326 | - | C>T | 60 | 46979 | 20.72 | 5.308e-06 | 1.832 |
| chr13:82565122 | rs1280002 | - | G>A | 103 | 207089 | 20.67 | 5.463e-06 | 0.6184 |
| chr9:111574525 | rs17801419 | - | A>G | 44 | 31525 | 20.59 | 5.703e-06 | 2.0 |
| chr5:92945156 | rs318105 | - | C>T | 160 | 159061 | 20.42 | 6.21e-06 | 1.497 |
| chr22:43298426 | rs117551605 | PACSIN2 | C>A | 35 | 23053 | 20.24 | 6.833e-06 | 2.143 |
| chr13:27316298 | rs117878987 | - | A>G | 24 | 13691 | 20.1 | 7.353e-06 | 2.462 |
| chr2:46724671 | rs115574807 | ATP6V1E2 | A>G | 59 | 46622 | 19.48 | 1.015e-05 | 1.807 |
| chr3:24335220 | rs75361937 | THRB | C>T | 66 | 54058 | 19.48 | 1.018e-05 | 1.757 |
| chr8:145689667 | rs142152732 | CYHR1 | C>G | 37 | 25326 | 19.29 | 1.122e-05 | 2.067 |
| chr6:92712489 | rs79102072 | - | G>A | 37 | 21233 | 31.32 | 2.183e-08 | 2.498 |
| chr1:207578564 | rs56310041 | - | C>T | 22 | 10847 | 25.83 | 3.731e-07 | 2.868 |
| chr10:15343723 | rs57306636 | FAM171A1 | A>G | 257 | 273035 | 25.45 | 4.54e-07 | 1.491 |
| chr13:100607344 | rs80169367 | - | G>T | 34 | 20641 | 24.97 | 5.821e-07 | 2.35 |
| chr5:92945156 | rs318105 | - | C>T | 157 | 151942 | 24.31 | 8.187e-07 | 1.564 |
| chr15:78424369 | rs72732571 | IDH3A | A>C | 24 | 12858 | 23.7 | 1.126e-06 | 2.649 |
| chr1:27332637 | rs151266984 | TENT5B | T>G | 23 | 12182 | 23.3 | 1.386e-06 | 2.678 |
| chr10:15415828 | rs77079513 | - | T>C | 21 | 10815 | 22.65 | 1.948e-06 | 2.757 |
| chr13:27316298 | rs117878987 | - | A>G | 24 | 13322 | 21.71 | 3.17e-06 | 2.548 |
| chr2:46724671 | rs115574807 | ATP6V1E2 | A>G | 59 | 45971 | 20.93 | 4.77e-06 | 1.849 |
| chr6:140821294 | rs62429835 | - | T>A | 36 | 24364 | 20.61 | 5.635e-06 | 2.14 |
| chr20:4210613 | rs118181669 | ADRA1D | C>T | 22 | 12067 | 20.52 | 5.899e-06 | 2.579 |
| chr22:43298426 | rs117551605 | PACSIN2 | C>A | 34 | 22242 | 20.34 | 6.491e-06 | 2.171 |
| chr5:92680028 | rs2343707 | - | A>G | 186 | 191901 | 20.2 | 6.963e-06 | 1.471 |
| chr13:41015950 | rs74369099 | - | C>T | 25 | 14588 | 20.11 | 7.305e-06 | 2.425 |
| chr1:207303477 | rs75202466 | C4BPA | T>C | 24 | 13969 | 19.87 | 8.269e-06 | 2.454 |
| chr14:62206548 | rs2301113 | HIF1A | A>C | 100 | 203629 | 19.68 | 9.171e-06 | 0.6207 |
| chr13:82565122 | rs1280002 | - | G>A | 97 | 196471 | 19.64 | 9.361e-06 | 0.6169 |
| chr3:24335220 | rs75361937 | THRB | C>T | 65 | 53252 | 19.6 | 9.527e-06 | 1.77 |
| chr3:27953384 | rs114195666 | - | T>C | 36 | 24512 | 19.44 | 1.038e-05 | 2.094 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr20:10986278 | rs118008636 | - | C>T | 6 | 14 | 22.28 | 2.358e-06 | 0.1342 |
| chr4:20047097 | rs16869098 | - | T>C | 31 | 31 | 22.23 | 2.415e-06 | 0.3005 |
| chr7:118020725 | rs10255887 | ANKRD7 | G>A | 3 | 11 | 22.17 | 2.491e-06 | 0.08541 |
| chr20:11048999 | rs117508848 | - | G>T | 13 | 19 | 21.13 | 4.301e-06 | 0.2113 |
| chr19:4742238 | rs12460850 | - | G>A | 15 | 20 | 20.28 | 6.677e-06 | 0.2311 |
| chr11:36120480 | rs80219938 | LDLRAD3 | G>A | 1 | 8 | 19.92 | 8.056e-06 | 0.03997 |
| chr12:80597844 | rs10778719 | OTOGL | C>T | 196 | 101 | 19.9 | 8.159e-06 | 0.4934 |
| chr2:208560001 | rs76100888 | - | T>C | 14 | 19 | 19.5 | 1.006e-05 | 0.2286 |
| chr8:18546543 | rs17644811 | PSD3 | T>C | 2 | 9 | 19.31 | 1.11e-05 | 0.07083 |
| chr9:103473681 | rs74212697 | - | A>G | 2 | 9 | 19.25 | 1.149e-05 | 0.07104 |
| chr3:135031027 | rs112461594 | - | G>A | 3 | 10 | 19.11 | 1.233e-05 | 0.09531 |
| chr3:62606184 | rs114266327 | CADPS | A>T | 3 | 10 | 19.04 | 1.279e-05 | 0.0956 |
| chr15:46801599 | rs117380401 | - | T>C | 3 | 10 | 19.04 | 1.279e-05 | 0.0956 |
| chr18:71636992 | rs28604594 | - | A>G | 103 | 63 | 18.66 | 1.56e-05 | 0.4575 |
| chr1:78714535 | rs2025292 | - | C>T | 15 | 19 | 18.46 | 1.736e-05 | 0.2421 |
| chr17:76445231 | rs7223548 | DNAH17 | G>C | 37 | 32 | 18.37 | 1.821e-05 | 0.3478 |
| chr15:79327299 | rs117849714 | RASGRF1 | A>G | 15 | 19 | 18.08 | 2.117e-05 | 0.2453 |
| chr20:11081580 | rs76797565 | - | C>G | 14 | 18 | 17.66 | 2.647e-05 | 0.2401 |
| chr2:50826828 | rs60788817 | NRXN1 | A>G | 186 | 31 | 17.46 | 2.932e-05 | 2.382 |
| chr17:75319681 | rs16969898 | SEPTIN9 | G>T | 42 | 34 | 17.16 | 3.436e-05 | 0.373 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: D140 | Middle ear, nasal cavity and accessory sinuses | 2/20 |
| ID | Name | Top Correlation |
|---|