Statistics
| Case | Control |
|---|---|
| 805 | 459389 |
Phenotype Definition
Respiratory failure in the newborn. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr19:34664325 | rs10422534 | LSM14A | G>A | 127 | 44802 | 28.9 | 7.64e-08 | 1.634 |
| chr23:130412178 | rs4524963 | IGSF1 | G>C | 535 | 311707 | 28.1 | 1.151e-07 | 0.7531 |
| chr4:33591552 | rs16989044 | - | A>G | 130 | 47847 | 24.57 | 7.175e-07 | 1.566 |
| chr9:30094854 | rs1857654 | - | T>G | 61 | 18584 | 23.41 | 1.311e-06 | 1.862 |
| chr8:34706724 | rs74319599 | - | T>C | 52 | 15277 | 22.67 | 1.927e-06 | 1.934 |
| chr1:69968819 | rs78282469 | - | G>A | 91 | 31336 | 22.61 | 1.985e-06 | 1.661 |
| chr13:102460341 | rs1322701 | FGF14 | A>G | 197 | 79958 | 22.37 | 2.251e-06 | 1.428 |
| chr15:65114484 | rs8031690 | PIF1 | G>A | 42 | 11678 | 21.56 | 3.427e-06 | 2.037 |
| chr14:73343239 | rs8010875 | DPF3 | G>A | 135 | 51372 | 21.41 | 3.701e-06 | 1.512 |
| chr4:36281837 | rs10029345 | - | G>A | 51 | 15146 | 21.39 | 3.749e-06 | 1.91 |
| chr1:90600783 | rs12562356 | - | C>T | 304 | 215515 | 20.72 | 5.308e-06 | 0.7504 |
| chr3:176237200 | rs1351800 | - | C>T | 799 | 396437 | 20.68 | 5.431e-06 | 1.245 |
| chr13:47863156 | rs8000212 | - | G>A | 174 | 69938 | 20.67 | 5.442e-06 | 1.436 |
| chr3:111554228 | rs6785777 | PLCXD2 | T>C | 87 | 30283 | 20.48 | 6.011e-06 | 1.638 |
| chr4:84331768 | rs4693623 | HELQ | T>C | 848 | 422535 | 20.47 | 6.052e-06 | 1.242 |
| chr3:43197817 | rs12489611 | - | C>T | 113 | 41827 | 20.46 | 6.082e-06 | 1.549 |
| chr1:244465254 | rs3102471 | - | A>G | 788 | 389835 | 19.83 | 8.475e-06 | 1.239 |
| chr16:80560659 | rs75740027 | - | T>C | 137 | 52925 | 19.83 | 8.445e-06 | 1.483 |
| chr9:114270410 | rs2026647 | - | T>C | 165 | 66341 | 19.78 | 8.685e-06 | 1.437 |
| chr10:95514432 | rs10509664 | - | C>T | 263 | 113570 | 19.51 | 1.003e-05 | 1.343 |
| chr8:34706724 | rs74319599 | - | T>C | 52 | 15067 | 25.2 | 5.157e-07 | 2.004 |
| chr23:130412178 | rs4524963 | IGSF1 | G>C | 501 | 297864 | 24.92 | 5.982e-07 | 0.7577 |
| chr3:149253949 | rs58783823 | WWTR1 | G>A | 26 | 6075 | 22.25 | 2.399e-06 | 2.468 |
| chr13:46503671 | rs9562629 | - | G>A | 163 | 65760 | 21.26 | 4.008e-06 | 1.461 |
| chr16:80560659 | rs75740027 | - | T>C | 133 | 51710 | 20.74 | 5.251e-06 | 1.507 |
| chr1:90600783 | rs12562356 | - | C>T | 272 | 198915 | 20.47 | 6.066e-06 | 0.7404 |
| chr5:18178389 | rs11950780 | - | G>A | 182 | 75378 | 20.38 | 6.342e-06 | 1.425 |
| chr13:35423040 | rs7318381 | - | T>C | 257 | 188267 | 20.12 | 7.282e-06 | 0.7376 |
| chr6:127830000 | rs9491801 | AL096711.2 | C>T | 64 | 21170 | 19.98 | 7.841e-06 | 1.757 |
| chr9:114270410 | rs2026647 | - | T>C | 152 | 61429 | 19.89 | 8.182e-06 | 1.46 |
| chr11:125303807 | rs34141026 | - | A>G | 257 | 112950 | 19.89 | 8.21e-06 | 1.353 |
| chr14:73343239 | rs8010875 | DPF3 | G>A | 122 | 47226 | 19.72 | 8.946e-06 | 1.517 |
| chr4:2341194 | rs2071680 | ZFYVE28 | C>T | 607 | 396516 | 19.59 | 9.586e-06 | 0.7965 |
| chr13:46505599 | rs71431394 | - | T>C | 160 | 65192 | 19.47 | 1.021e-05 | 1.442 |
| chr10:95514432 | rs10509664 | - | C>T | 245 | 106943 | 19.45 | 1.031e-05 | 1.357 |
| chr5:52836514 | rs114770246 | - | T>C | 41 | 11984 | 19.37 | 1.076e-05 | 1.982 |
| chr14:73582301 | rs362439 | RBM25 | C>T | 195 | 82454 | 19.17 | 1.193e-05 | 1.396 |
| chr6:1305687 | rs62388390 | - | G>A | 101 | 38069 | 19.11 | 1.234e-05 | 1.563 |
| chr23:149420111 | rs112893161 | - | A>G | 36 | 8893 | 19.05 | 1.275e-05 | 2.06 |
| chr15:29665115 | rs8037595 | FAM189A1 | T>C | 187 | 78888 | 18.85 | 1.414e-05 | 1.4 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr5:165109865 | rs34056036 | - | A>G | 140 | 72 | 25.97 | 3.467e-07 | 0.4574 |
| chr5:88138731 | rs11951031 | MEF2C | C>T | 83 | 50 | 23.5 | 1.252e-06 | 0.4132 |
| chr8:131960656 | rs7815277 | ADCY8 | T>C | 145 | 73 | 22.74 | 1.855e-06 | 0.485 |
| chr16:90084561 | rs11648785 | DBNDD1 | C>T | 544 | 93 | 21.84 | 2.962e-06 | 1.803 |
| chr3:20267818 | rs80181101 | - | C>T | 10 | 14 | 20.45 | 6.108e-06 | 0.1848 |
| chr9:84603019 | rs1999661 | - | C>T | 30 | 25 | 20.38 | 6.352e-06 | 0.3067 |
| chr6:166013748 | rs118174059 | PDE10A | G>C | 53 | 35 | 19.58 | 9.667e-06 | 0.3828 |
| chr4:35790972 | rs10019864 | - | C>G | 870 | 177 | 19.55 | 9.793e-06 | 1.603 |
| chr10:108615678 | rs72827207 | SORCS1 | C>T | 31 | 25 | 19.48 | 1.018e-05 | 0.3164 |
| chr12:69133950 | rs7962663 | NUP107 | A>G | 743 | 250 | 19.4 | 1.058e-05 | 0.6298 |
| chr1:245965252 | rs76371141 | SMYD3 | C>T | 29 | 24 | 19.39 | 1.066e-05 | 0.309 |
| chr2:54353453 | rs35295105 | ACYP2 | A>G | 14 | 16 | 19.2 | 1.176e-05 | 0.2261 |
| chr3:20388173 | rs78600729 | - | A>G | 14 | 16 | 19.2 | 1.176e-05 | 0.2261 |
| chr6:157910732 | rs241588 | ZDHHC14 | C>T | 578 | 104 | 18.9 | 1.376e-05 | 1.698 |
| chr9:22938308 | rs79729048 | - | G>A | 38 | 28 | 18.78 | 1.467e-05 | 0.3469 |
| chr16:3307475 | rs11466011 | - | C>T | 30 | 24 | 18.75 | 1.493e-05 | 0.3169 |
| chr21:25595567 | rs2828919 | - | T>C | 193 | 86 | 18.67 | 1.553e-05 | 0.5455 |
| chr18:58951545 | rs7227872 | - | C>T | 136 | 66 | 18.61 | 1.6e-05 | 0.5062 |
| chr19:56744689 | rs73067870 | ZSCAN5A | A>G | 74 | 43 | 18.59 | 1.617e-05 | 0.4323 |
| chr11:114633076 | rs116868446 | - | T>C | 97 | 4 | 18.53 | 1.675e-05 | 6.768 |
| chr5:88138731 | rs11951031 | MEF2C | C>T | 77 | 50 | 26.78 | 2.283e-07 | 0.3847 |
| chr5:165109865 | rs34056036 | - | A>G | 130 | 67 | 23.66 | 1.149e-06 | 0.461 |
| chr10:108615678 | rs72827207 | SORCS1 | C>T | 28 | 25 | 22.21 | 2.449e-06 | 0.2871 |
| chr6:157910732 | rs241588 | ZDHHC14 | C>T | 552 | 98 | 20.6 | 5.667e-06 | 1.767 |
| chr19:54434126 | rs10411229 | CACNG7 | T>G | 688 | 133 | 20.39 | 6.327e-06 | 1.681 |
| chr4:175023326 | rs62338788 | - | A>G | 20 | 20 | 20.35 | 6.448e-06 | 0.2591 |
| chr3:20267818 | rs80181101 | - | C>T | 10 | 14 | 20.12 | 7.259e-06 | 0.1866 |
| chr1:245965252 | rs76371141 | SMYD3 | C>T | 28 | 24 | 19.99 | 7.783e-06 | 0.3009 |
| chr5:37922538 | rs4869559 | - | A>C | 694 | 238 | 19.38 | 1.07e-05 | 0.6193 |
| chr8:13725740 | rs79200734 | - | C>T | 35 | 27 | 19.13 | 1.222e-05 | 0.334 |
| chr21:25595567 | rs2828919 | - | T>C | 170 | 79 | 18.91 | 1.368e-05 | 0.5282 |
| chr1:57517318 | rs116566276 | DAB1 | G>A | 14 | 16 | 18.9 | 1.378e-05 | 0.2281 |
| chr3:20388173 | rs78600729 | - | A>G | 14 | 16 | 18.86 | 1.405e-05 | 0.2284 |
| chr20:58559654 | rs1474909 | CDH26 | C>A | 120 | 61 | 18.64 | 1.576e-05 | 0.4905 |
| chr11:114633076 | rs116868446 | - | T>C | 96 | 4 | 18.62 | 1.597e-05 | 6.803 |
| chr4:35790972 | rs10019864 | - | C>G | 815 | 168 | 18.52 | 1.679e-05 | 1.607 |
| chr19:56744689 | rs73067870 | ZSCAN5A | A>G | 71 | 42 | 18.39 | 1.803e-05 | 0.4284 |
| chr16:3307475 | rs11466011 | - | C>T | 30 | 24 | 18.38 | 1.814e-05 | 0.3196 |
| chr5:59773582 | rs77540604 | PDE4D | T>C | 32 | 25 | 18.29 | 1.893e-05 | 0.3285 |
| chr1:18000613 | rs869526 | ARHGEF10L | G>A | 81 | 46 | 18.24 | 1.95e-05 | 0.4463 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: R090 | Asphyxia | 1/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: O622 | Other uterine inertia | 0/20 |