Statistics
| Case | Control |
|---|---|
| 745 | 459449 |
Phenotype Definition
Overgrowth of the outer labia. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32593507 | rs9271720 | - | G>A | 638 | 453357 | 23.33 | 1.363e-06 | 0.7802 |
| chr6:32599999 | rs9272105 | HLA-DQA1 | G>A | 682 | 481672 | 22.31 | 2.321e-06 | 0.7864 |
| chr5:123746171 | rs7705687 | - | T>C | 613 | 436732 | 21.8 | 3.032e-06 | 0.7856 |
| chr6:32594916 | rs9271824 | - | A>G | 648 | 457316 | 21.18 | 4.175e-06 | 0.7901 |
| chr2:236187746 | rs74661965 | - | G>A | 45 | 14316 | 21.12 | 4.312e-06 | 1.98 |
| chr25:333275 | rs5987274 | - | T>C | 710 | 384479 | 21.02 | 4.55e-06 | 1.261 |
| chr2:168629336 | rs77352129 | - | A>G | 108 | 43605 | 20.98 | 4.638e-06 | 1.574 |
| chr8:128549089 | rs79636191 | - | C>T | 38 | 11474 | 20.96 | 4.685e-06 | 2.088 |
| chr2:168590290 | rs111642065 | - | T>C | 111 | 45096 | 20.68 | 5.441e-06 | 1.56 |
| chr6:32600404 | rs9272116 | HLA-DQA1 | T>C | 684 | 480568 | 20.38 | 6.34e-06 | 0.7943 |
| chr9:11068072 | rs58357208 | - | C>T | 181 | 81971 | 19.74 | 8.893e-06 | 1.419 |
| chr3:191897218 | rs975121 | FGF12 | G>A | 858 | 477430 | 19.71 | 9.003e-06 | 1.252 |
| chr7:48801114 | rs117741354 | - | C>T | 44 | 14366 | 19.24 | 1.154e-05 | 1.934 |
| chr5:131612876 | rs162896 | P4HA2 | C>T | 81 | 31301 | 19.04 | 1.279e-05 | 1.638 |
| chr12:104562673 | rs78221103 | - | C>T | 41 | 13085 | 18.94 | 1.348e-05 | 1.968 |
| chr17:12990893 | rs78107574 | - | G>A | 70 | 26138 | 18.93 | 1.359e-05 | 1.693 |
| chr9:83162962 | rs62572770 | - | G>T | 132 | 56805 | 18.82 | 1.437e-05 | 1.481 |
| chr8:42800400 | rs77786122 | HOOK3 | A>G | 126 | 53965 | 18.7 | 1.534e-05 | 1.491 |
| chr15:80018493 | rs72732749 | - | G>T | 99 | 40248 | 18.61 | 1.602e-05 | 1.56 |
| chr7:137081750 | rs116974120 | DGKI | A>G | 50 | 17034 | 18.59 | 1.62e-05 | 1.842 |
| chr3:191897218 | rs975121 | FGF12 | G>A | 798 | 434173 | 23.8 | 1.066e-06 | 1.288 |
| chr20:62827895 | rs7265274 | MYT1 | T>G | 25 | 6089 | 23.55 | 1.219e-06 | 2.573 |
| chr7:50901104 | rs79344312 | - | C>T | 66 | 22747 | 23.44 | 1.287e-06 | 1.825 |
| chr10:31515132 | rs2484990 | - | C>T | 27 | 7011 | 21.54 | 3.46e-06 | 2.399 |
| chr2:168629336 | rs77352129 | - | A>G | 107 | 42838 | 21.14 | 4.269e-06 | 1.581 |
| chr7:57131423 | rs74636229 | - | G>A | 150 | 64796 | 20.89 | 4.858e-06 | 1.479 |
| chr6:32593507 | rs9271720 | - | G>A | 607 | 427203 | 20.82 | 5.04e-06 | 0.786 |
| chr2:168590290 | rs111642065 | - | T>C | 110 | 44325 | 20.68 | 5.43e-06 | 1.564 |
| chr2:46045551 | rs13431476 | PRKCE | C>T | 137 | 57869 | 20.47 | 6.073e-06 | 1.497 |
| chr2:236187746 | rs74661965 | - | G>A | 43 | 13573 | 20.33 | 6.517e-06 | 1.985 |
| chr5:123746171 | rs7705687 | - | T>C | 596 | 420273 | 20.08 | 7.429e-06 | 0.7891 |
| chr21:24027256 | rs12483587 | - | T>C | 129 | 54422 | 19.83 | 8.478e-06 | 1.504 |
| chr15:80018493 | rs72732749 | - | G>T | 99 | 39606 | 19.59 | 9.577e-06 | 1.579 |
| chr10:31512098 | rs2484992 | - | C>T | 26 | 6929 | 19.42 | 1.046e-05 | 2.335 |
| chr8:128549089 | rs79636191 | - | C>T | 37 | 11294 | 19.33 | 1.102e-05 | 2.05 |
| chr6:32599999 | rs9272105 | HLA-DQA1 | G>A | 647 | 451458 | 19.28 | 1.126e-05 | 0.795 |
| chr19:51845371 | rs10414211 | VSIG10L | G>T | 720 | 391080 | 19.25 | 1.15e-05 | 1.255 |
| chr5:131612876 | rs162896 | P4HA2 | C>T | 80 | 30765 | 18.77 | 1.471e-05 | 1.638 |
| chr6:32594916 | rs9271824 | - | A>G | 617 | 430888 | 18.68 | 1.543e-05 | 0.7968 |
| chr12:12094208 | rs78137435 | - | C>T | 64 | 23362 | 18.63 | 1.583e-05 | 1.726 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32593507 | rs9271720 | - | G>A | 638 | 178817 | 23.01 | 1.616e-06 | 0.7813 |
| chr5:123746171 | rs7705687 | - | T>C | 613 | 172954 | 22.9 | 1.706e-06 | 0.7807 |
| chr6:32599999 | rs9272105 | HLA-DQA1 | G>A | 682 | 189833 | 21.67 | 3.236e-06 | 0.7888 |
| chr2:236187746 | rs74661965 | - | G>A | 45 | 5613 | 21.46 | 3.606e-06 | 1.993 |
| chr6:32594916 | rs9271824 | - | A>G | 648 | 180366 | 20.88 | 4.897e-06 | 0.7912 |
| chr25:333275 | rs5987274 | - | T>C | 710 | 152007 | 20.46 | 6.074e-06 | 1.258 |
| chr2:168629336 | rs77352129 | - | A>G | 108 | 17349 | 20.13 | 7.247e-06 | 1.561 |
| chr3:191897218 | rs975121 | FGF12 | G>A | 858 | 188197 | 20.12 | 7.285e-06 | 1.255 |
| chr8:128549089 | rs79636191 | - | C>T | 38 | 4590 | 20.07 | 7.468e-06 | 2.06 |
| chr2:168590290 | rs111642065 | - | T>C | 111 | 17905 | 20.06 | 7.499e-06 | 1.551 |
| chr6:32600404 | rs9272116 | HLA-DQA1 | T>C | 684 | 189413 | 19.84 | 8.416e-06 | 0.7965 |
| chr9:11068072 | rs58357208 | - | C>T | 181 | 32378 | 19.6 | 9.553e-06 | 1.418 |
| chr21:24027256 | rs12483587 | - | T>C | 134 | 22812 | 18.76 | 1.485e-05 | 1.477 |
| chr8:42800400 | rs77786122 | HOOK3 | A>G | 126 | 21275 | 18.75 | 1.487e-05 | 1.493 |
| chr5:131612876 | rs162896 | P4HA2 | C>T | 81 | 12402 | 18.67 | 1.556e-05 | 1.632 |
| chr15:80018493 | rs72732749 | - | G>T | 99 | 15868 | 18.65 | 1.567e-05 | 1.562 |
| chr7:57131423 | rs74636229 | - | G>A | 155 | 27255 | 18.54 | 1.667e-05 | 1.438 |
| chr2:25691325 | rs79765644 | DTNB | C>T | 171 | 30556 | 18.52 | 1.678e-05 | 1.416 |
| chr7:48801114 | rs117741354 | - | C>T | 44 | 5731 | 18.51 | 1.693e-05 | 1.913 |
| chr17:12990893 | rs78107574 | - | G>A | 70 | 10369 | 18.47 | 1.723e-05 | 1.684 |
| chr20:62827895 | rs7265274 | MYT1 | T>G | 25 | 2398 | 23.71 | 1.121e-06 | 2.588 |
| chr7:50901104 | rs79344312 | - | C>T | 66 | 9004 | 23.38 | 1.326e-06 | 1.826 |
| chr3:191897218 | rs975121 | FGF12 | G>A | 798 | 172253 | 23.09 | 1.545e-06 | 1.284 |
| chr10:31515132 | rs2484990 | - | C>T | 27 | 2700 | 22.91 | 1.702e-06 | 2.467 |
| chr7:57131423 | rs74636229 | - | G>A | 150 | 25611 | 21.04 | 4.505e-06 | 1.482 |
| chr2:46045551 | rs13431476 | PRKCE | C>T | 137 | 22813 | 20.91 | 4.807e-06 | 1.505 |
| chr10:31512098 | rs2484992 | - | C>T | 26 | 2667 | 20.72 | 5.318e-06 | 2.403 |
| chr2:168629336 | rs77352129 | - | A>G | 107 | 17046 | 20.59 | 5.682e-06 | 1.573 |
| chr2:236187746 | rs74661965 | - | G>A | 43 | 5346 | 20.58 | 5.725e-06 | 1.996 |
| chr5:123746171 | rs7705687 | - | T>C | 596 | 166610 | 20.41 | 6.241e-06 | 0.7873 |
| chr2:168590290 | rs111642065 | - | T>C | 110 | 17602 | 20.37 | 6.373e-06 | 1.56 |
| chr6:32593507 | rs9271720 | - | G>A | 607 | 168971 | 20.37 | 6.399e-06 | 0.7879 |
| chr15:80018493 | rs72732749 | - | G>T | 99 | 15620 | 19.91 | 8.127e-06 | 1.586 |
| chr21:24027256 | rs12483587 | - | T>C | 129 | 21525 | 19.89 | 8.213e-06 | 1.506 |
| chr19:51845371 | rs10414211 | VSIG10L | G>T | 720 | 154762 | 19.42 | 1.05e-05 | 1.257 |
| chr12:12094208 | rs78137435 | - | C>T | 64 | 9160 | 19.28 | 1.126e-05 | 1.744 |
| chr3:103416050 | rs115956529 | - | C>T | 56 | 7722 | 19.11 | 1.234e-05 | 1.802 |
| chr10:31495974 | rs1250307 | - | A>G | 25 | 2625 | 18.79 | 1.461e-05 | 2.345 |
| chr10:113129539 | rs76286912 | - | C>T | 33 | 3866 | 18.75 | 1.489e-05 | 2.113 |
| chr6:32599999 | rs9272105 | HLA-DQA1 | G>A | 647 | 178476 | 18.65 | 1.569e-05 | 0.7978 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: L980 | Pyogenic granuloma | 2/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: C519 | Vulva, unspecified | 0/20 |
| ICD-10: D071 | Vulva | 0/20 |
| ICD-10: D280 | Vulva | 0/20 |