Constitutional symptom


Normal Case/Contol

GWAS of 0025142

Sibling Case/Control

No sibling GWAS available 0025142


Case Control
234487 225707

Phenotype Definition

A symptom or manifestation indicating a systemic or general effect of a disease and that may affect the general well-being or status of an individual. []

Phenotype Comment

Note that we use the preferred term label constitutional symptom because this reflects common usage, but we do not restrict the term or its descendents to the narrow meaning of symptom, i.e., a complaint related by a patient to a physician. There is no generally accepted classification of what defines a constitutional symptom, but examples include weight loss, fatigue, general weakness, night sweats, shaking, chills, fever, and vomiting.

Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: I209 Angina pectoris, unspecified 1/20
ICD: I848 Unspecified haemorrhoids with other complications 1/20
ICD: K30 Dyspepsia 2/20
ICD: K409 Unilateral or unspecified inguinal hernia, without obstruction or gangrene 2/20
ICD: K801 Calculus of gallbladder with other cholecystitis 3/20
ICD: K802 Calculus of gallbladder without cholecystitis 3/20
ICD: K804 Calculus of bile duct with cholecystitis 1/20
ICD: K805 Calculus of bile duct without cholangitis or cholecystitis 2/20
ICD: L989 Disorder of skin and subcutaneous tissue, unspecified 2/20
ICD: M169 Coxarthrosis, unspecified 2/20
ICD: M189 Arthrosis of first carpometacarpal joint, unspecified 2/20
ICD: M1994 Arthrosis, unspecified (Hand) 2/20
ICD: M1997 Arthrosis, unspecified (Ankle and foot) 2/20
ICD: M202 Hallux rigidus 2/20
ICD: M841 Nonunion of fracture [pseudarthrosis] 1/20
ICD: N393 Stress incontinence 2/20
ICD: N811 Cystocele 2/20
ICD: R101 Pain localised to upper abdomen 1/20
ICD: R102 Pelvic and perineal pain 1/20
ICD: R104 Other and unspecified abdominal pain 2/20
ICD: R194 Change in bowel habit 2/20
ICD: R33 Retention of urine 4/20