0025408

Case	Control
10317	449877

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr20:33971914	rs4911494	UQCC1	T>C	8681	361319	22.56	2.034e-06	1.069
chr20:33972899	rs4911179	UQCC1	C>A	8677	361278	22.02	2.698e-06	1.068
chr10:115922208	rs17776701	CCDC186	C>T	2355	93013	21.72	3.155e-06	1.108
chr9:118701934	rs10983022	-	G>A	610	21877	21.55	3.44e-06	1.213
chr20:33975181	rs6088813	UQCC1	A>C	8675	361473	21.5	3.529e-06	1.067
chr20:34025983	rs78110303	GDF5	A>G	8592	357929	21.39	3.747e-06	1.067
chr5:78586460	rs2404143	JMY	C>T	678	34923	20.66	5.475e-06	0.8363
chr12:118395933	rs79879869	KSR2	C>T	1656	64321	20.65	5.525e-06	1.125
chr18:19047571	rs8092018	GREB1L	G>A	4122	167463	20.24	6.826e-06	1.082
chr10:115840882	rs11592629	-	T>C	2393	95009	20.08	7.413e-06	1.103
chr14:75459633	rs175016	-	C>T	10642	446328	19.95	7.958e-06	1.063
chr18:58258805	rs72979219	-	A>G	440	15329	19.87	8.3e-06	1.243
chr9:132947473	rs4448387	NCS1	C>A	476	25296	19.86	8.349e-06	0.812
chr18:19034556	rs3794938	GREB1L	T>C	4088	166142	19.83	8.458e-06	1.081
chr5:5042466	rs114530427	-	G>A	182	10965	19.78	8.676e-06	0.7173
chr18:45833529	rs16949059	ZBTB7C	C>G	2378	94496	19.46	1.029e-05	1.102
chr16:60081785	rs7200383	-	T>G	836	31135	19.42	1.047e-05	1.17
chr4:88368830	rs4324526	NUDT9	A>G	7225	326310	18.83	1.43e-05	0.9389
chr16:716273	rs11866949	WDR90	T>C	3237	130572	18.81	1.444e-05	1.087
chr5:5038608	rs72650147	-	G>A	368	19893	18.8	1.45e-05	0.7949
chr10:115922208	rs17776701	CCDC186	C>T	2297	90505	25.4	4.656e-07	1.12
chr9:118701934	rs10983022	-	G>A	600	21467	23.24	1.431e-06	1.224
chr10:115840882	rs11592629	-	T>C	2325	92449	21.75	3.103e-06	1.11
chr18:58258805	rs72979219	-	A>G	429	14891	21.29	3.948e-06	1.256
chr14:75572265	rs96358	ZC2HC1C	G>A	8191	343455	20.27	6.73e-06	1.067
chr3:84480665	rs12632655	-	G>A	3953	161512	19.91	8.115e-06	1.083
chr14:75459633	rs175016	-	C>T	9992	421253	19.91	8.111e-06	1.065
chr4:88368830	rs4324526	NUDT9	A>G	6787	309127	19.82	8.518e-06	0.9355
chr18:45833529	rs16949059	ZBTB7C	C>G	2183	86884	19.77	8.73e-06	1.107
chr10:115899540	rs35060624	CCDC186	C>T	1765	69632	19.44	1.039e-05	1.118
chr16:89148643	rs9935216	-	C>T	4109	190614	19.43	1.042e-05	0.9252
chr3:84603909	rs35563441	-	G>A	4341	178078	19.11	1.233e-05	1.079
chr4:65475995	rs80077365	-	G>A	706	26126	19.07	1.262e-05	1.184
chr14:75513828	rs175080	MLH3	G>A	9853	416944	18.79	1.457e-05	1.063
chr1:209055813	rs11119146	-	T>C	909	45629	18.71	1.525e-05	0.8624
chr10:115922492	rs12782946	CCDC186	C>T	2001	79524	18.66	1.562e-05	1.108
chr6:396321	rs12203592	IRF4	C>T	4717	194198	18.53	1.675e-05	1.075
chr2:5600812	rs792068	-	T>C	6581	299664	18.48	1.716e-05	0.9371
chr14:75455810	rs175012	-	A>C	9880	417390	18.43	1.766e-05	1.062
chr15:92246643	rs117527651	-	G>A	1893	74960	18.37	1.822e-05	1.11

Location

SNP

Gene

Ref>Alt

Alt in Case

Alt in Control

Chi-square

P-value

Odds ratio

chr20:33971914

rs4911494

UQCC1

T>C

8681

361319

22.56

2.034e-06

1.069

chr20:33972899

rs4911179

UQCC1

C>A

8677

361278

22.02

2.698e-06

1.068

chr10:115922208

rs17776701

CCDC186

C>T

2355

93013

21.72

3.155e-06

1.108

chr9:118701934

rs10983022

-

G>A

610

21877

21.55

3.44e-06

1.213

chr20:33975181

rs6088813

UQCC1

A>C

8675

361473

21.5

3.529e-06

1.067

chr20:34025983

rs78110303

GDF5

A>G

8592

357929

21.39

3.747e-06

1.067

chr5:78586460

rs2404143

JMY

C>T

678

34923

20.66

5.475e-06

0.8363

chr12:118395933

rs79879869

KSR2

C>T

1656

64321

20.65

5.525e-06

1.125

chr18:19047571

rs8092018

GREB1L

G>A

4122

167463

20.24

6.826e-06

1.082

chr10:115840882

rs11592629

-

T>C

2393

95009

20.08

7.413e-06

1.103

chr14:75459633

rs175016

-

C>T

10642

446328

19.95

7.958e-06

1.063

chr18:58258805

rs72979219

-

A>G

440

15329

19.87

8.3e-06

1.243

chr9:132947473

rs4448387

NCS1

C>A

476

25296

19.86

8.349e-06

0.812

chr18:19034556

rs3794938

GREB1L

T>C

4088

166142

19.83

8.458e-06

1.081

chr5:5042466

rs114530427

-

G>A

182

10965

19.78

8.676e-06

0.7173

chr18:45833529

rs16949059

ZBTB7C

C>G

2378

94496

19.46

1.029e-05

1.102

chr16:60081785

rs7200383

-

T>G

836

31135

19.42

1.047e-05

1.17

chr4:88368830

rs4324526

NUDT9

A>G

7225

326310

18.83

1.43e-05

0.9389

chr16:716273

rs11866949

WDR90

T>C

3237

130572

18.81

1.444e-05

1.087

chr5:5038608

rs72650147

-

G>A

368

19893

18.8

1.45e-05

0.7949

chr10:115922208

rs17776701

CCDC186

C>T

2297

90505

25.4

4.656e-07

1.12

chr9:118701934

rs10983022

-

G>A

600

21467

23.24

1.431e-06

1.224

chr10:115840882

rs11592629

-

T>C

2325

92449

21.75

3.103e-06

1.11

chr18:58258805

rs72979219

-

A>G

429

14891

21.29

3.948e-06

1.256

chr14:75572265

rs96358

ZC2HC1C

G>A

8191

343455

20.27

6.73e-06

1.067

chr3:84480665

rs12632655

-

G>A

3953

161512

19.91

8.115e-06

1.083

chr14:75459633

rs175016

-

C>T

9992

421253

19.91

8.111e-06

1.065

chr4:88368830

rs4324526

NUDT9

A>G

6787

309127

19.82

8.518e-06

0.9355

chr18:45833529

rs16949059

ZBTB7C

C>G

2183

86884

19.77

8.73e-06

1.107

chr10:115899540

rs35060624

CCDC186

C>T

1765

69632

19.44

1.039e-05

1.118

chr16:89148643

rs9935216

-

C>T

4109

190614

19.43

1.042e-05

0.9252

chr3:84603909

rs35563441

-

G>A

4341

178078

19.11

1.233e-05

1.079

chr4:65475995

rs80077365

-

G>A

706

26126

19.07

1.262e-05

1.184

chr14:75513828

rs175080

MLH3

G>A

9853

416944

18.79

1.457e-05

1.063

chr1:209055813

rs11119146

-

T>C

909

45629

18.71

1.525e-05

0.8624

chr10:115922492

rs12782946

CCDC186

C>T

2001

79524

18.66

1.562e-05

1.108

chr6:396321

rs12203592

IRF4

C>T

4717

194198

18.53

1.675e-05

1.075

chr2:5600812

rs792068

-

T>C

6581

299664

18.48

1.716e-05

0.9371

chr14:75455810

rs175012

-

A>C

9880

417390

18.43

1.766e-05

1.062

chr15:92246643

rs117527651

-

G>A

1893

74960

18.37

1.822e-05

1.11

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr10:115922208	rs17776701	CCDC186	C>T	2297	45226	22.92	1.686e-06	1.115
chr9:118701934	rs10983022	-	G>A	600	10725	21.76	3.084e-06	1.219
chr18:58258805	rs72979219	-	A>G	429	7414	20.76	5.217e-06	1.256
chr3:84480665	rs12632655	-	G>A	3953	80216	20.74	5.259e-06	1.086
chr4:88368830	rs4324526	NUDT9	A>G	6787	154090	20.69	5.411e-06	0.9334
chr18:45833529	rs16949059	ZBTB7C	C>G	2183	43142	20.33	6.522e-06	1.11
chr10:115840882	rs11592629	-	T>C	2325	46136	20.15	7.166e-06	1.107
chr1:209055813	rs11119146	-	T>C	909	22815	19.51	1.003e-05	0.8584
chr4:65475995	rs80077365	-	G>A	706	12962	19.34	1.095e-05	1.189
chr7:35946779	rs10233082	-	A>G	6966	144796	19.14	1.216e-05	1.068
chr3:84603909	rs35563441	-	G>A	4341	88629	19.11	1.231e-05	1.08
chr11:33958433	rs4756085	-	C>T	3826	77795	18.86	1.408e-05	1.083
chr10:115899540	rs35060624	CCDC186	C>T	1765	34685	18.74	1.497e-05	1.117
chr14:75572265	rs96358	ZC2HC1C	G>A	8191	171231	18.39	1.798e-05	1.064
chr16:89148643	rs9935216	-	C>T	4109	94694	17.82	2.434e-05	0.9276
chr18:2305971	rs890327	-	T>G	3830	88452	17.66	2.64e-05	0.926
chr3:194704787	rs1996383	-	T>C	6765	153195	17.63	2.684e-05	0.9383
chr5:5042466	rs114530427	-	G>A	181	5377	17.56	2.788e-05	0.7285
chr14:75459633	rs175016	-	C>T	9992	210109	17.41	3.008e-05	1.062
chr19:53420774	rs11669026	ZNF888	C>T	8481	190653	17.38	3.057e-05	0.9414

ID	Name	Top Correlation
ICD-10: B963	Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0/20
ICD-10: C252	Tail of pancreas	0/20
ICD-10: D730	Hyposplenism	0/20
ICD-10: D735	Infarction of spleen	0/20
ICD-10: D759	Disease of blood and blood-forming organs, unspecified	0/20
ICD-10: I859	Oesophageal varices without bleeding	0/20
ICD-10: J920	Pleural plaque with presence of asbestos	0/20
ICD-10: J929	Pleural plaque without asbestos	0/20
ICD-10: R100	Acute abdomen	0/20
ICD-10: R161	Splenomegaly, not elsewhere classified	0/20
ICD-10: R162	Hepatomegaly with splenomegaly, not elsewhere classified	0/20
ICD-10: R590	Localised enlarged lymph nodes	0/20
ICD-10: R591	Generalised enlarged lymph nodes	0/20
ICD-10: Y848	Other medical procedures	0/20

Abnormal spleen morphology

0025408

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information

Associated Diseases ^ⓘ

Abnormal spleen morphology

0025408

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ