Abnormal bronchus morphology

0025426

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

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Interactive Plot

Statistics

Case	Control
46284	413910

Phenotype Definition

Any anomaly of the morphology of the bronchi. []

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	5178	61880	378.5	2.583e-84	0.7493
chr5:33958959	rs28777	SLC45A2	A>C	4354	52638	342.3	1.986e-76	0.7425
chr5:33955326	rs35390	SLC45A2	A>C	3087	38060	273.5	1.935e-61	0.7309
chr5:33955673	rs35391	SLC45A2	C>T	3078	37902	270.4	9.389e-61	0.7319
chr15:48426484	rs1426654	SLC24A5	A>G	1971	25555	236.3	2.545e-53	0.6968
chr5:33951116	rs35397	SLC45A2	T>G	7605	82503	232.5	1.665e-52	0.8267
chr23:71651365	rs12007867	AL133500.1	C>T	591	10080	219.6	1.116e-49	0.538
chr6:93667780	rs9363020	-	G>A	712	11279	212.6	3.78e-48	0.5722
chr15:48392165	rs1834640	-	A>G	2380	29244	204.3	2.456e-46	0.7354
chr2:144305674	rs6704689	ARHGAP15	A>G	18751	155024	195.2	2.279e-44	1.128
chr17:9586811	rs73975789	USP43	A>G	869	12791	193.4	5.615e-44	0.6156
chr2:136407479	rs1446585	R3HDM1	A>G	24561	241837	180.3	4.262e-41	0.901
chr2:3313043	rs73133173	EIPR1	A>C	954	13509	178.1	1.285e-40	0.6404
chr6:170602429	rs17860704	DLL1	T>C	731	10987	176.9	2.293e-40	0.6037
chr16:57068106	rs3995818	NLRC5	A>G	994	13890	174.4	8.191e-40	0.6488
chr6:93645908	rs77956657	-	T>C	1031	14295	174.2	8.785e-40	0.6539
chr10:78274538	rs2130801	LRMDA	A>G	722	10733	166.9	3.599e-38	0.6104
chr1:169510139	rs13306334	F5	G>A	737	10871	164.7	1.067e-37	0.6153
chr5:177915428	rs7730172	COL23A1	C>T	1168	15590	162.4	3.42e-37	0.6793
chr2:135837906	rs7570971	RAB3GAP1	C>A	28265	275308	162.3	3.483e-37	0.9096
chr2:144305674	rs6704689	ARHGAP15	A>G	18078	146231	197.4	7.579e-45	1.131
chr2:144428286	rs12691689	ARHGAP15	C>T	28491	241863	97.88	4.441e-23	1.077
chr2:144403796	rs13409480	ARHGAP15	A>G	46521	401935	95.71	1.332e-22	1.07
chr2:144301488	rs34406675	ARHGAP15	G>A	7490	59866	91.18	1.31e-21	1.13
chr10:25815417	rs3923088	GPR158	A>G	43981	380878	75.98	2.872e-18	1.062
chr2:144450181	rs1996447	ARHGAP15	T>G	33684	289641	71.9	2.263e-17	1.063
chr2:56040099	rs10199082	-	T>C	13276	110473	71.35	2.999e-17	1.087
chr10:25821318	rs10508700	GPR158	T>C	42784	394723	71.31	3.046e-17	0.9429
chr9:136137065	rs687621	ABO	A>G	28319	264428	70.17	5.429e-17	0.9389
chr9:136139265	rs657152	ABO	C>A	30246	281725	69.82	6.51e-17	0.9402
chr9:136149229	rs505922	ABO	T>C	28242	263651	68.63	1.187e-16	0.9396
chr9:136142355	rs643434	ABO	G>A	30358	282666	68.4	1.335e-16	0.9408
chr9:136142203	rs514659	ABO	A>C	27414	255720	68.29	1.413e-16	0.939
chr9:136143442	rs612169	ABO	A>G	28384	264759	66.32	3.831e-16	0.9407
chr9:136132908	rs8176719	ABO	T>TC	30295	281988	64.99	7.528e-16	0.9421
chr7:102466741	rs1541519	FBXL13	G>T	32179	277260	59.3	1.356e-14	1.058
chr1:234362972	rs10910388	SLC35F3	A>G	12611	105599	56.35	6.074e-14	1.079
chr6:32407906	rs41270488	HLA-DRA	T>C	5503	54474	55.34	1.014e-13	0.8972
chr7:102527517	rs10241865	FBXL13	G>A	34119	294941	55.15	1.115e-13	1.055
chr21:47398647	rs7281388	-	C>A	13865	116957	50.46	1.218e-12	1.072

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr1:192511183	rs10489868	-	T>C	21093	1914	29.35	6.04e-08	1.156
chr2:144305674	rs6704689	ARHGAP15	A>G	18078	1650	21.42	3.684e-06	1.14
chr9:77776101	rs773019	-	T>C	11308	1304	21.42	3.689e-06	0.8644
chr2:199182325	rs12466968	PLCL1	C>T	5916	487	21.31	3.9e-06	1.25
chr18:30640189	rs4556865	CCDC178	A>G	19963	2222	21.28	3.978e-06	0.8888
chr1:234556098	rs74397124	TARBP1	C>T	2891	375	20.52	5.91e-06	0.7765
chr7:147619621	rs7791949	CNTNAP2	G>A	24185	2658	19.83	8.459e-06	0.8983
chr2:2460597	rs823543	-	C>T	44349	4284	19.77	8.735e-06	1.101
chr15:101969052	rs2643350	PCSK6	A>G	15453	1738	19.59	9.62e-06	0.8835
chr7:125696608	rs117326610	-	G>A	3542	275	19.32	1.104e-05	1.321
chr17:11645082	rs62061840	DNAH9	A>G	4631	374	19.13	1.218e-05	1.271
chr2:2464675	Affx-19742929	-	C>T	34874	3761	19.09	1.244e-05	0.9078
chr23:69163134	rs1938023	EDA	A>G	2515	318	19.01	1.303e-05	0.7674
chr12:80059628	rs117270283	PAWR	T>C	2520	329	18.94	1.352e-05	0.7719
chr10:92632424	rs61857742	RPP30	C>G	2219	159	18.81	1.447e-05	1.429
chr9:139498558	rs117656202	-	G>A	6242	525	18.47	1.726e-05	1.222
chr13:32928404	rs1460817	BRCA2	T>C	25623	2407	18.36	1.825e-05	1.112
chr13:20831472	rs56044432	-	A>G	2414	177	18.23	1.956e-05	1.397
chr10:18481525	rs77726527	CACNB2	C>T	1711	233	18.1	2.102e-05	0.7411
chr3:147378666	rs17511206	-	C>A	6204	739	17.96	2.251e-05	0.8424

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: D573	Sickle-cell trait	1/20
ICD: J441	Chronic obstructive pulmonary disease with acute exacerbation, unspecified	1/20
ICD: J981	Pulmonary collapse	1/20
ICD: K573	Diverticular disease of large intestine without perforation or abscess	8/20
ICD: K579	Diverticular disease of intestine, part unspecified, without perforation or abscess	9/20

ID	Name	Top Correlation
ICD-10: B449	Aspergillosis, unspecified	0/20
ICD-10: C340	Main bronchus	0/20
ICD-10: G440	Cluster headache syndrome	0/20
ICD-10: J152	Pneumonia due to staphylococcus	0/20
ICD-10: J40	Bronchitis, not specified as acute or chronic	0/20
ICD-10: J42	Unspecified chronic bronchitis	0/20
ICD-10: J432	Centrilobular emphysema	0/20
ICD-10: J47	Bronchiectasis	0/20
ICD-10: J869	Pyothorax without fistula	0/20
ICD-10: K571	Diverticular disease of small intestine without perforation or abscess	0/20
ICD-10: K572	Diverticular disease of large intestine with perforation and abscess	0/20
ICD-10: K578	Diverticular disease of intestine, part unspecified, with perforation and abscess	0/20
ICD-10: R093	Abnormal sputum	0/20

Abnormal bronchus morphology

0025426

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ