Statistics
| Case | Control |
|---|---|
| 4691 | 455503 |
Phenotype Definition
A structural abnormality of the ureter. The ureter is the duct by which urine passes from the kidney to the bladder. []
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr13:114504663 | rs41284482 | TMEM255B | G>A | 208 | 14470 | 24.13 | 9.024e-07 | 1.412 |
| chr8:40246254 | rs75528130 | - | A>G | 237 | 17030 | 22.62 | 1.976e-06 | 1.368 |
| chr10:63717836 | rs72833363 | ARID5B | C>T | 377 | 46763 | 22.47 | 2.13e-06 | 0.7793 |
| chr9:112964736 | rs4246877 | C9orf152 | T>C | 1218 | 104611 | 22.06 | 2.641e-06 | 1.155 |
| chr3:6718768 | rs17045636 | - | G>A | 630 | 51288 | 21.45 | 3.629e-06 | 1.211 |
| chr13:77272457 | rs115069062 | - | C>T | 269 | 19883 | 21.23 | 4.077e-06 | 1.331 |
| chr18:36988137 | rs11877246 | - | C>T | 539 | 63675 | 20.9 | 4.835e-06 | 0.8162 |
| chr21:27749876 | rs2830193 | - | T>C | 1236 | 135943 | 20.62 | 5.594e-06 | 0.8705 |
| chr3:82200397 | rs79300077 | - | G>T | 880 | 74232 | 20.24 | 6.834e-06 | 1.173 |
| chr13:77266350 | rs9600759 | - | T>C | 309 | 23508 | 19.64 | 9.352e-06 | 1.293 |
| chr9:7689927 | rs1332910 | - | C>G | 1127 | 97208 | 19.3 | 1.118e-05 | 1.15 |
| chr8:139999840 | rs111494341 | - | T>C | 239 | 17595 | 19.27 | 1.134e-05 | 1.334 |
| chr2:160141580 | rs11675075 | WDSUB1 | A>G | 4496 | 459982 | 19.26 | 1.139e-05 | 0.9148 |
| chr6:116305183 | rs6939175 | FRK | G>A | 3811 | 352375 | 19.17 | 1.195e-05 | 1.095 |
| chr1:221317254 | rs116462660 | - | G>A | 194 | 13844 | 19.14 | 1.212e-05 | 1.375 |
| chr8:100350744 | rs13260338 | VPS13B | T>C | 1078 | 92658 | 19.1 | 1.242e-05 | 1.152 |
| chr10:15194361 | rs79251353 | NMT2 | A>G | 270 | 20214 | 19.07 | 1.259e-05 | 1.311 |
| chr2:160075886 | rs146371641 | TANC1 | GC>G | 4409 | 451974 | 18.87 | 1.401e-05 | 0.9153 |
| chr3:80074897 | rs115786051 | - | G>A | 376 | 29425 | 18.8 | 1.455e-05 | 1.257 |
| chr13:77182103 | rs9600747 | - | G>T | 254 | 18927 | 18.78 | 1.47e-05 | 1.318 |
| chr10:63717836 | rs72833363 | ARID5B | C>T | 357 | 45078 | 25.69 | 4.009e-07 | 0.7605 |
| chr8:40246254 | rs75528130 | - | A>G | 236 | 16829 | 22.84 | 1.763e-06 | 1.372 |
| chr21:27749876 | rs2830193 | - | T>C | 1142 | 126147 | 22.4 | 2.217e-06 | 0.8607 |
| chr9:112964736 | rs4246877 | C9orf152 | T>C | 1201 | 102740 | 21.36 | 3.809e-06 | 1.154 |
| chr3:6718768 | rs17045636 | - | G>A | 622 | 50543 | 20.37 | 6.367e-06 | 1.207 |
| chr13:114504663 | rs41284482 | TMEM255B | G>A | 200 | 14177 | 19.93 | 8.046e-06 | 1.377 |
| chr13:77272457 | rs115069062 | - | C>T | 251 | 18439 | 19.9 | 8.165e-06 | 1.332 |
| chr13:41842561 | rs1591127 | - | T>C | 670 | 55280 | 19.42 | 1.048e-05 | 1.194 |
| chr3:82200397 | rs79300077 | - | G>T | 867 | 72996 | 19.0 | 1.308e-05 | 1.169 |
| chr13:77266350 | rs9600759 | - | T>C | 297 | 22522 | 18.57 | 1.636e-05 | 1.291 |
| chr4:59958177 | rs56255875 | - | A>G | 671 | 55435 | 18.43 | 1.761e-05 | 1.189 |
| chr1:221317254 | rs116462660 | - | G>A | 192 | 13693 | 18.38 | 1.812e-05 | 1.368 |
| chr6:116305183 | rs6939175 | FRK | G>A | 3683 | 338952 | 18.36 | 1.832e-05 | 1.095 |
| chr3:122687018 | rs60776642 | SEMA5B | G>A | 432 | 34253 | 18.3 | 1.892e-05 | 1.236 |
| chr12:10562025 | rs1841957 | KLRC4-KLRK1 | T>C | 2517 | 259741 | 18.24 | 1.947e-05 | 0.9037 |
| chr4:99685875 | rs11942265 | - | G>T | 3856 | 354960 | 18.22 | 1.972e-05 | 1.094 |
| chr15:92249722 | rs72762020 | - | T>C | 481 | 38585 | 18.22 | 1.963e-05 | 1.222 |
| chr13:77182103 | rs9600747 | - | G>T | 247 | 18358 | 17.88 | 2.357e-05 | 1.315 |
| chr13:47056349 | rs117128013 | - | C>T | 287 | 21764 | 17.8 | 2.456e-05 | 1.289 |
| chr4:99699147 | rs4605663 | - | G>A | 4406 | 407638 | 17.46 | 2.936e-05 | 1.091 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr7:54621134 | rs964823 | VSTM2A | A>C | 2477 | 9590 | 25.07 | 5.527e-07 | 1.14 |
| chr8:40246254 | rs75528130 | - | A>G | 236 | 706 | 23.06 | 1.573e-06 | 1.438 |
| chr10:63717836 | rs72833363 | ARID5B | C>T | 357 | 1977 | 21.46 | 3.622e-06 | 0.7626 |
| chr3:133656433 | rs6439448 | SLCO2A1 | C>A | 2076 | 8017 | 20.9 | 4.837e-06 | 1.136 |
| chr5:167559743 | rs17550124 | TENM2 | G>A | 1593 | 7603 | 20.41 | 6.245e-06 | 0.8721 |
| chr19:6744762 | rs339405 | TRIP10 | C>A | 1612 | 6128 | 20.35 | 6.454e-06 | 1.148 |
| chr1:221317254 | rs116462660 | - | G>A | 192 | 567 | 19.87 | 8.277e-06 | 1.453 |
| chr2:202793266 | rs6722501 | - | G>A | 418 | 2248 | 19.8 | 8.589e-06 | 0.7849 |
| chr3:6718768 | rs17045636 | - | G>A | 622 | 2181 | 19.62 | 9.43e-06 | 1.231 |
| chr4:59958177 | rs56255875 | - | A>G | 671 | 2378 | 19.31 | 1.111e-05 | 1.22 |
| chr2:106027586 | rs59683937 | FHL2 | G>T | 1173 | 4373 | 19.26 | 1.142e-05 | 1.166 |
| chr10:15194361 | rs79251353 | NMT2 | A>G | 264 | 830 | 19.15 | 1.209e-05 | 1.366 |
| chr3:105467984 | rs115868309 | CBLB | T>C | 180 | 531 | 18.82 | 1.44e-05 | 1.456 |
| chr1:30255396 | rs10753253 | - | A>G | 1541 | 5846 | 18.81 | 1.445e-05 | 1.145 |
| chr13:77272457 | rs115069062 | - | C>T | 251 | 787 | 18.76 | 1.486e-05 | 1.373 |
| chr14:29579407 | rs4981683 | - | C>T | 3168 | 12599 | 18.57 | 1.639e-05 | 1.111 |
| chr13:41842561 | rs1591127 | - | T>C | 670 | 2399 | 18.23 | 1.953e-05 | 1.213 |
| chr18:4488582 | rs1658190 | - | A>G | 2556 | 11778 | 18.11 | 2.083e-05 | 0.8948 |
| chr11:118251534 | rs73020208 | UBE4A | G>A | 306 | 997 | 17.65 | 2.649e-05 | 1.321 |
| chr3:6475872 | rs17044885 | - | C>T | 314 | 1029 | 17.53 | 2.825e-05 | 1.315 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: N133 | Other and unspecified hydronephrosis | 2/20 |