Autoimmune antibody positivity

0030057

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
16678	443516

Phenotype Definition

The presence of an antibody in the blood circulation that is directed against the organism's own cells or tissues. []

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr6:32607376	rs34250758	HLA-DQA1	G>A	8084	182179	221.8	3.653e-50	1.212
chr6:32577973	rs532965	-	T>G	7687	172850	213.1	2.95e-48	1.211
chr6:32583357	rs6931277	-	A>T	7514	169178	210.0	1.386e-47	1.212
chr6:32581973	rs521539	-	G>A	8589	195208	209.5	1.802e-47	1.2
chr6:32577380	rs660895	-	A>G	8562	195085	203.1	4.404e-46	1.197
chr6:32582650	rs3104413	-	C>G	7607	171462	202.9	4.764e-46	1.207
chr6:32402778	rs9268614	-	T>G	8882	207576	143.0	5.755e-33	1.161
chr6:32282854	rs6910071	TSBP1	A>G	8761	204839	138.6	5.403e-32	1.159
chr6:32379295	rs9268515	-	G>C	7479	172891	137.3	1.023e-31	1.168
chr6:32303848	rs28361060	TSBP1	G>A	8763	205097	136.8	1.352e-31	1.158
chr6:32387809	rs2395163	-	T>C	8721	204062	136.0	1.961e-31	1.158
chr6:32375973	rs3763309	-	C>A	8731	204350	135.7	2.336e-31	1.157
chr6:32371915	rs3793127	BTNL2	C>T	8737	204627	134.7	3.913e-31	1.157
chr6:32257284	rs9268145	TSBP1	T>G	8744	204884	134.1	5.253e-31	1.156
chr6:32333341	rs9268362	TSBP1	A>G	8768	205643	132.5	1.14e-30	1.155
chr6:32376348	rs3763312	-	G>A	8659	203216	129.0	6.832e-30	1.154
chr6:32338986	rs2073044	TSBP1	C>T	9972	238251	113.9	1.383e-26	1.137
chr6:32406342	rs3129871	-	C>A	11994	338851	105.6	9.247e-25	0.8895
chr6:32681355	rs9275595	-	T>C	8656	206335	95.23	1.696e-22	1.131
chr6:32401217	rs3135338	-	T>C	11132	314796	94.36	2.626e-22	0.8932
chr6:32607376	rs34250758	HLA-DQA1	G>A	7742	175548	238.4	8.786e-54	1.227
chr6:32577973	rs532965	-	T>G	7389	167278	228.9	1.038e-51	1.226
chr6:32583357	rs6931277	-	A>T	7223	163733	225.6	5.569e-51	1.227
chr6:32581973	rs521539	-	G>A	8166	186929	223.3	1.707e-50	1.214
chr6:32582650	rs3104413	-	C>G	7308	165886	218.9	1.535e-49	1.221
chr6:32577380	rs660895	-	A>G	8139	186828	216.4	5.501e-49	1.211
chr6:32379295	rs9268515	-	G>C	7270	168916	157.0	5.103e-36	1.185
chr6:32402778	rs9268614	-	T>G	8437	198682	155.3	1.212e-35	1.174
chr6:32282854	rs6910071	TSBP1	A>G	8510	200470	155.2	1.291e-35	1.173
chr6:32303848	rs28361060	TSBP1	G>A	8514	200723	153.3	3.325e-35	1.172
chr6:32257284	rs9268145	TSBP1	T>G	8493	200502	150.5	1.33e-34	1.17
chr6:32333341	rs9268362	TSBP1	A>G	8519	201263	149.4	2.393e-34	1.169
chr6:32387809	rs2395163	-	T>C	8293	195536	147.8	5.143e-34	1.17
chr6:32375973	rs3763309	-	C>A	8307	196080	145.4	1.718e-33	1.168
chr6:32371915	rs3793127	BTNL2	C>T	8312	196342	144.4	2.865e-33	1.168
chr6:32376348	rs3763312	-	G>A	8237	195011	138.4	6.084e-32	1.165
chr6:32406342	rs3129871	-	C>A	10939	316720	120.9	3.94e-28	0.8776
chr6:32338986	rs2073044	TSBP1	C>T	9427	227817	117.8	1.896e-27	1.145
chr6:32448129	rs4410767	-	T>C	16672	417017	113.6	1.602e-26	1.126
chr6:32428772	rs9268839	-	A>G	16728	418688	110.1	9.326e-26	1.124

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr8:145639681	rs1871534	SLC39A4	G>C	825	402	74.47	6.161e-18	0.5897
chr5:147863034	rs9325101	HTR4	A>G	739	367	72.53	1.643e-17	0.5793
chr8:10557760	rs57041981	RP1L1	A>G	740	358	64.27	1.084e-15	0.5954
chr4:111516322	rs113989538	-	T>A	594	301	63.8	1.375e-15	0.5683
chr3:45987980	rs2234355	FYCO1	G>A	429	235	63.21	1.856e-15	0.5269
chr10:108763241	rs73371935	SORCS1	C>G	834	390	61.73	3.93e-15	0.6153
chr4:76788564	rs34155925	PPEF2	C>T	442	238	60.82	6.257e-15	0.5361
chr10:108751262	rs7091076	SORCS1	T>G	918	419	60.49	7.403e-15	0.6293
chr1:159174683	rs2814778	ACKR1	T>C	899	412	60.35	7.942e-15	0.6272
chr2:185043361	rs1997132	-	T>C	456	243	60.04	9.272e-15	0.5421
chr3:188327555	rs7645635	LPP	T>C	649	318	59.66	1.129e-14	0.5886
chr9:129979758	rs3780318	RALGPS1	G>A	720	341	56.51	5.593e-14	0.6086
chr6:32607376	rs34250758	HLA-DQA1	G>A	8084	2003	55.45	9.573e-14	1.231
chr16:50711334	rs1131716	SNX20	G>A	504	257	55.28	1.047e-13	0.5663
chr6:136480972	rs9483910	PDE7B	C>T	959	427	55.21	1.084e-13	0.6458
chr9:129984107	rs3739553	RALGPS1	G>A	692	328	54.46	1.584e-13	0.6085
chr12:80106323	rs2463171	-	G>A	1301	548	54.37	1.663e-13	0.682
chr12:132549300	rs7136109	EP400	A>G	479	246	54.09	1.919e-13	0.5626
chr14:33956209	rs1012023	NPAS3	C>A	1384	575	53.26	2.922e-13	0.691
chr9:79488840	rs12342344	PRUNE2	A>G	972	429	53.24	2.949e-13	0.6519
chr6:32607376	rs34250758	HLA-DQA1	G>A	7742	1894	46.66	8.448e-12	1.217
chr6:32448129	rs4410767	-	T>C	16672	4401	42.81	6.045e-11	1.165
chr6:32583357	rs6931277	-	A>T	7223	1765	42.72	6.318e-11	1.214
chr6:32428772	rs9268839	-	A>G	16728	4413	41.68	1.076e-10	1.162
chr6:32577973	rs532965	-	T>G	7389	1818	41.64	1.095e-10	1.207
chr6:32447341	rs29001568	-	G>A	16171	4307	37.76	8.011e-10	1.155
chr6:32590953	rs9271588	-	T>C	17697	4714	37.49	9.202e-10	1.153
chr6:32582650	rs3104413	-	C>G	7308	1810	36.84	1.282e-09	1.195
chr6:32402778	rs9268614	-	T>G	8437	2137	32.54	1.169e-08	1.17
chr6:32581973	rs521539	-	G>A	8166	2070	31.21	2.312e-08	1.169
chr6:32577380	rs660895	-	A>G	8139	2061	31.17	2.369e-08	1.169
chr6:32375973	rs3763309	-	C>A	8307	2104	31.15	2.382e-08	1.167
chr6:32371915	rs3793127	BTNL2	C>T	8312	2110	30.96	2.637e-08	1.167
chr6:32387809	rs2395163	-	T>C	8293	2105	30.64	3.098e-08	1.166
chr6:32379295	rs9268515	-	G>C	7270	1826	30.4	3.523e-08	1.175
chr6:32378866	rs5007265	-	G>T	15013	4588	30.14	4.022e-08	0.88
chr6:32663999	rs6457620	-	G>C	16808	4497	30.03	4.253e-08	1.136
chr6:32375745	rs6926737	-	A>G	15005	4586	29.96	4.413e-08	0.8804
chr6:32379239	rs5007258	-	G>A	15018	4589	29.83	4.723e-08	0.8805
chr6:32659878	rs9275224	-	A>G	16884	4508	29.75	4.914e-08	1.136

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: K743	Primary biliary cirrhosis	2/20
ICD: M059	Seropositive rheumatoid arthritis, unspecified	18/20
ICD: M069	Rheumatoid arthritis, unspecified	17/20

ID	Name	Top Correlation
ICD-10: B182	Chronic viral hepatitis C	0/20
ICD-10: D367	Other specified sites	0/20
ICD-10: D487	Other specified sites	0/20
ICD-10: D591	Other autoimmune haemolytic anaemias	0/20
ICD-10: D695	Secondary thrombocytopenia	0/20
ICD-10: G610	Guillain-Barre syndrome	0/20
ICD-10: G700	Myasthenia gravis	0/20
ICD-10: J849	Interstitial pulmonary disease, unspecified	0/20
ICD-10: K745	Biliary cirrhosis, unspecified	0/20
ICD-10: K754	Autoimmune hepatitis	0/20
ICD-10: L439	Lichen planus, unspecified	0/20
ICD-10: M060	Seronegative rheumatoid arthritis	0/20
ICD-10: M130	Polyarthritis, unspecified	0/20
ICD-10: M329	Systemic lupus erythematosus, unspecified	0/20
ICD-10: M349	Systemic sclerosis, unspecified	0/20
ICD-10: O034	Incomplete, without complication	0/20
ICD-10: O039	Complete or unspecified, without complication	0/20
ICD-10: O120	Gestational oedema	0/20
ICD-10: R945	Abnormal results of liver function studies	0/20

Autoimmune antibody positivity

0030057

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ