Abnormal vascular physiology

0030163

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
84887	375307

Phenotype Definition

Abnormality of vascular function. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr9:22096055	rs10757274	-	A>G	89480	383072	93.98	3.186e-22	1.052
chr9:22098574	rs4977574	-	A>G	89102	381319	93.84	3.425e-22	1.052
chr9:22088260	rs10757272	-	C>T	89292	382456	88.69	4.618e-21	1.05
chr9:22124477	rs10757278	-	A>G	88221	377879	86.49	1.406e-20	1.05
chr9:22125347	rs1333048	-	A>C	91431	392226	85.12	2.803e-20	1.049
chr9:22125503	rs1333049	-	G>C	88219	378219	79.66	4.447e-19	1.048
chr9:22115959	rs2383207	-	G>A	84059	377980	71.27	3.117e-17	0.9569
chr6:160608804	rs16891156	SLC22A2	A>C	4819	18544	68.79	1.095e-16	1.145
chr6:161010118	rs10455872	LPA	A>G	14508	59191	68.56	1.23e-16	1.083
chr9:22081850	rs6475606	-	C>T	91370	392899	67.48	2.133e-16	1.044
chr6:160997118	rs74617384	LPA	A>T	14122	57705	64.7	8.722e-16	1.082
chr9:22083404	rs1333040	-	T>C	73013	328603	59.38	1.303e-14	0.9599
chr8:112002658	rs79922463	-	G>C	12441	51068	48.77	2.872e-12	1.075
chr9:22029445	rs10965215	AL359922.1	G>A	86706	373748	47.05	6.925e-12	1.036
chr9:22068652	rs4977756	-	A>G	69928	314128	46.57	8.818e-12	0.9641
chr9:22003223	rs3217992	AL359922.1	C>T	66938	287366	46.38	9.737e-12	1.038
chr4:100239319	rs1229984	ADH1B	C>T	5201	25275	45.26	1.728e-11	0.9013
chr2:210564805	rs13424278	MAP2	A>G	3492	13521	44.94	2.028e-11	1.137
chr6:396321	rs12203592	IRF4	C>T	38359	162846	44.57	2.459e-11	1.044
chr9:22053687	rs10965219	-	A>G	89846	387905	43.79	3.656e-11	1.035
chr9:22098574	rs4977574	-	A>G	84515	364211	87.08	1.043e-20	1.052
chr9:22096055	rs10757274	-	A>G	84751	365402	86.06	1.742e-20	1.051
chr9:22088260	rs10757272	-	C>T	84206	363000	84.47	3.901e-20	1.051
chr9:22124477	rs10757278	-	A>G	83609	360497	81.87	1.45e-19	1.05
chr9:22125503	rs1333049	-	G>C	83547	360371	79.06	6.012e-19	1.049
chr6:161010118	rs10455872	LPA	A>G	14311	58439	78.54	7.857e-19	1.09
chr9:22125347	rs1333048	-	A>C	86307	372834	78.08	9.873e-19	1.049
chr6:160997118	rs74617384	LPA	A>T	13927	56961	74.22	6.99e-18	1.089
chr9:22115959	rs2383207	-	G>A	80712	365309	70.42	4.79e-17	0.9558
chr9:22081850	rs6475606	-	C>T	83549	361213	66.61	3.304e-16	1.045
chr6:396321	rs12203592	IRF4	C>T	37905	161010	61.43	4.578e-15	1.052
chr9:22083404	rs1333040	-	T>C	68778	311780	59.47	1.241e-14	0.9587
chr6:160608804	rs16891156	SLC22A2	A>C	3844	14855	56.56	5.452e-14	1.147
chr6:160848743	rs9457925	SLC22A3	G>A	3506	13539	52.01	5.513e-13	1.148
chr6:160961137	rs3798220	LPA	T>C	3446	13336	49.33	2.165e-12	1.145
chr6:160922870	rs117733303	-	A>G	3482	13502	48.71	2.966e-12	1.143
chr1:201884952	rs2819348	LMOD1	T>C	61055	263453	45.32	1.67e-11	1.038
chr9:22003223	rs3217992	AL359922.1	C>T	63181	273069	43.26	4.79e-11	1.037
chr1:201860626	rs2250377	SHISA4	G>A	58063	250617	41.46	1.201e-10	1.037
chr6:160557643	rs2282143	SLC22A1	C>T	2953	11458	40.7	1.775e-10	1.142

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	13076	25229	109.1	1.582e-25	1.124
chr5:33958959	rs28777	SLC45A2	A>C	11124	21343	101.2	8.479e-24	1.129
chr5:33955673	rs35391	SLC45A2	C>T	8049	15285	85.59	2.219e-20	1.139
chr5:33955326	rs35390	SLC45A2	A>C	8076	15349	84.45	3.936e-20	1.138
chr9:22096055	rs10757274	-	A>G	89480	187560	79.08	5.976e-19	1.052
chr9:22088260	rs10757272	-	C>T	89292	187137	77.86	1.106e-18	1.052
chr9:22098574	rs4977574	-	A>G	89102	186719	77.7	1.2e-18	1.052
chr9:22125347	rs1333048	-	A>C	91431	191914	74.99	4.735e-18	1.051
chr9:22124477	rs10757278	-	A>G	88221	185043	72.54	1.64e-17	1.05
chr6:160608804	rs16891156	SLC22A2	A>C	4819	8976	66.73	3.119e-16	1.159
chr9:22125503	rs1333049	-	G>C	88219	185184	66.56	3.398e-16	1.048
chr9:22115959	rs2383207	-	G>A	84059	185308	66.42	3.651e-16	0.9546
chr5:33951116	rs35397	SLC45A2	T>G	17239	34493	66.13	4.224e-16	1.083
chr9:22081850	rs6475606	-	C>T	91370	192305	58.14	2.438e-14	1.044
chr9:22029445	rs10965215	AL359922.1	G>A	86706	182360	54.5	1.556e-13	1.043
chr9:22083404	rs1333040	-	T>C	73013	161023	52.44	4.446e-13	0.9589
chr9:22053687	rs10965219	-	A>G	89846	189314	51.22	8.269e-13	1.042
chr9:22003223	rs3217992	AL359922.1	C>T	66938	140318	48.42	3.433e-12	1.042
chr17:9586811	rs73975789	USP43	A>G	2705	4936	47.44	5.667e-12	1.18
chr6:161010118	rs10455872	LPA	A>G	14508	29182	46.77	7.966e-12	1.075
chr9:22098574	rs4977574	-	A>G	84515	178796	71.99	2.162e-17	1.051
chr9:22096055	rs10757274	-	A>G	84751	179388	71.56	2.685e-17	1.051
chr9:22088260	rs10757272	-	C>T	84206	178203	69.95	6.095e-17	1.05
chr9:22124477	rs10757278	-	A>G	83609	176972	68.83	1.074e-16	1.05
chr9:22125347	rs1333048	-	A>C	86307	182912	68.02	1.622e-16	1.05
chr9:22125503	rs1333049	-	G>C	83547	176901	65.74	5.155e-16	1.049
chr9:22115959	rs2383207	-	G>A	80712	179416	62.13	3.21e-15	0.9547
chr6:161010118	rs10455872	LPA	A>G	14311	28791	59.29	1.359e-14	1.086
chr6:160997118	rs74617384	LPA	A>T	13927	28061	56.3	6.221e-14	1.084
chr9:22081850	rs6475606	-	C>T	83549	177396	53.11	3.151e-13	1.044
chr9:22083404	rs1333040	-	T>C	68778	153102	50.98	9.323e-13	0.9583
chr9:22003223	rs3217992	AL359922.1	C>T	63181	133707	44.49	2.557e-11	1.041
chr9:22029445	rs10965215	AL359922.1	G>A	80892	172039	41.26	1.333e-10	1.038
chr9:22053687	rs10965219	-	A>G	82492	175604	40.87	1.63e-10	1.038
chr6:160848743	rs9457925	SLC22A3	G>A	3506	6683	39.5	3.284e-10	1.141
chr6:160608804	rs16891156	SLC22A2	A>C	3844	7381	38.81	4.673e-10	1.133
chr6:160961137	rs3798220	LPA	T>C	3446	6575	38.06	6.861e-10	1.14
chr6:160922870	rs117733303	-	A>G	3482	6659	37.41	9.566e-10	1.138
chr8:112002658	rs79922463	-	G>C	11764	23919	35.4	2.68e-09	1.072
chr9:22033366	rs2157719	-	T>C	72346	160139	34.98	3.324e-09	0.9655

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: I208	Other forms of angina pectoris	9/20
ICD: I209	Angina pectoris, unspecified	14/20
ICD: I501	Left ventricular failure	8/20
ICD: I702	Atherosclerosis of arteries of the extremities	11/20
ICD: I73	Other peripheral vascular diseases	8/20

ID	Name	Top Correlation
ICD-10: B961	Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0/20
ICD-10: C349	Bronchus or lung, unspecified	0/20
ICD-10: G458	Other transient cerebral ischaemic attacks and related syndromes	0/20
ICD-10: H538	Other visual disturbances	0/20
ICD-10: I080	Disorders of both mitral and aortic valves	0/20
ICD-10: I151	Hypertension secondary to other renal disorders	0/20
ICD-10: I201	Angina pectoris with documented spasm	0/20
ICD-10: I270	Primary pulmonary hypertension	0/20
ICD-10: I272	Other secondary pulmonary hypertension	0/20
ICD-10: I460	Cardiac arrest with successful resuscitation	0/20
ICD-10: I601	Subarachnoid haemorrhage from middle cerebral artery	0/20
ICD-10: I603	Subarachnoid haemorrhage from posterior communicating artery	0/20
ICD-10: I609	Subarachnoid haemorrhage, unspecified	0/20
ICD-10: I672	Cerebral atherosclerosis	0/20
ICD-10: I690	Sequelae of subarachnoid haemorrhage	0/20
ICD-10: I728	Aneurysm of other specified arteries	0/20
ICD-10: I730	Raynaud's syndrome	0/20
ICD-10: I776	Arteritis, unspecified	0/20
ICD-10: I792	Peripheral angiopathy in diseases classified elsewhere	0/20
ICD-10: I81	Portal vein thrombosis	0/20
ICD-10: I822	Embolism and thrombosis of vena cava	0/20
ICD-10: I830	Varicose veins of lower extremities with ulcer	0/20
ICD-10: I831	Varicose veins of lower extremities with inflammation	0/20
ICD-10: I832	Varicose veins of lower extremities with both ulcer and inflammation	0/20
ICD-10: I839	Varicose veins of lower extremities without ulcer or inflammation	0/20
ICD-10: I871	Compression of vein	0/20
ICD-10: I872	Venous insufficiency (chronic) (peripheral)	0/20
ICD-10: I878	Other specified disorders of veins	0/20
ICD-10: I952	Hypotension due to drugs	0/20
ICD-10: J150	Pneumonia due to Klebsiella pneumoniae	0/20
ICD-10: J960	Acute respiratory failure	0/20
ICD-10: K224	Dyskinesia of oesophagus	0/20
ICD-10: M316	Other giant cell arteritis	0/20
ICD-10: M349	Systemic sclerosis, unspecified	0/20
ICD-10: M353	Polymyalgia rheumatica	0/20
ICD-10: M544	Lumbago with sciatica	0/20
ICD-10: Q273	Peripheral arteriovenous malformation	0/20
ICD-10: R068	Other and unspecified abnormalities of breathing	0/20
ICD-10: R072	Precordial pain	0/20
ICD-10: R073	Other chest pain	0/20
ICD-10: R074	Chest pain, unspecified	0/20
ICD-10: R101	Pain localised to upper abdomen	0/20
ICD-10: R601	Generalised oedema	0/20
ICD-10: R700	Elevated erythrocyte sedimentation rate	0/20
ICD-10: R778	Other specified abnormalities of plasma proteins	0/20
ICD-10: T404	Other synthetic narcotics	0/20
ICD-10: Y86	Sequelae of other accidents	0/20

Abnormal vascular physiology

0030163

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ