Female Case | Female Control | % Female |
---|---|---|
43265 | 206592 | 51% |
Male Case | Male Control | % Male |
---|---|---|
41622 | 168715 | 49% |
Abnormality of vascular function. [HPO:probinson]
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr2:66725070 | rs12995572 | MEIS1 | G>C | 2961 | 12202 | 47.83 | 4.638e-12 | 1.155 |
chr6:136480972 | rs9483910 | PDE7B | C>T | 2383 | 9758 | 41.49 | 1.186e-10 | 1.161 |
chr2:11885177 | rs58914318 | - | T>G | 1650 | 6746 | 38.37 | 5.848e-10 | 1.187 |
chr5:33951693 | rs16891982 | SLC45A2 | G>C | 6742 | 29465 | 38.11 | 6.69e-10 | 1.09 |
chr5:33958959 | rs28777 | SLC45A2 | A>C | 5774 | 25066 | 37.78 | 7.927e-10 | 1.097 |
chr9:129562274 | rs78594581 | - | C>T | 1555 | 6200 | 37.74 | 8.084e-10 | 1.192 |
chr8:112002658 | rs79922463 | - | G>C | 6409 | 27964 | 37.01 | 1.173e-09 | 1.091 |
chr9:21931609 | rs7868374 | - | A>G | 1781 | 7362 | 36.46 | 1.559e-09 | 1.175 |
chr10:124948232 | rs73362778 | - | G>A | 1426 | 5784 | 36.18 | 1.802e-09 | 1.196 |
chr2:56909573 | rs6732353 | - | C>T | 1653 | 6794 | 36.03 | 1.941e-09 | 1.181 |
chr23:64367019 | rs7064929 | - | G>A | 2493 | 10356 | 35.6 | 2.427e-09 | 1.144 |
chr6:3217822 | rs9501951 | - | C>T | 1643 | 6771 | 34.67 | 3.909e-09 | 1.177 |
chr23:6492543 | rs5989589 | - | C>T | 9240 | 41038 | 34.57 | 4.116e-09 | 1.074 |
chr6:134087290 | rs9493730 | - | T>C | 1895 | 7903 | 34.31 | 4.699e-09 | 1.163 |
chr1:217511930 | rs964347 | - | G>A | 1503 | 6155 | 34.24 | 4.88e-09 | 1.185 |
chr16:88787704 | rs8043924 | PIEZO1 | C>G | 11905 | 53367 | 33.74 | 6.307e-09 | 1.065 |
chr11:4643101 | rs10836365 | - | G>A | 1555 | 6399 | 33.36 | 7.676e-09 | 1.179 |
chr7:114015707 | rs12705960 | FOXP2 | A>C | 46095 | 213789 | 33.35 | 7.717e-09 | 1.043 |
chr8:116784186 | rs7018138 | - | C>A | 1813 | 7555 | 33.31 | 7.872e-09 | 1.165 |
chr11:4643496 | rs10768125 | - | G>A | 1683 | 6983 | 32.65 | 1.104e-08 | 1.169 |
chr2:136608646 | rs4988235 | - | A>G | 19297 | 98217 | 34.83 | 3.597e-09 | 0.9476 |
chr8:112002658 | rs79922463 | - | G>C | 6087 | 26880 | 32.09 | 1.472e-08 | 1.087 |
chr6:396321 | rs12203592 | IRF4 | C>T | 19304 | 88576 | 31.53 | 1.962e-08 | 1.052 |
chr2:136707982 | rs6754311 | - | T>C | 19310 | 98046 | 30.62 | 3.141e-08 | 0.9508 |
chr2:136407479 | rs1446585 | R3HDM1 | A>G | 20299 | 100534 | 30.12 | 4.055e-08 | 0.9528 |
chr6:34827085 | rs9469913 | UHRF1BP1 | A>T | 14348 | 65516 | 28.05 | 1.185e-07 | 1.055 |
chr3:50153356 | rs1138536 | RBM5 | C>T | 38328 | 178949 | 27.89 | 1.281e-07 | 1.041 |
chr2:136608231 | rs4954490 | - | A>G | 15777 | 80350 | 27.55 | 1.533e-07 | 0.9499 |
chr7:114015707 | rs12705960 | FOXP2 | A>C | 42695 | 199894 | 27.37 | 1.679e-07 | 1.04 |
chr2:136488978 | rs6739713 | - | A>G | 13623 | 69614 | 27.12 | 1.909e-07 | 0.9476 |
chr6:34552797 | rs2814944 | - | G>A | 13133 | 59880 | 27.1 | 1.933e-07 | 1.056 |
chr2:136553639 | rs1011361 | - | A>G | 14371 | 73316 | 27.0 | 2.031e-07 | 0.9487 |
chr2:135907088 | rs6730157 | - | A>G | 20517 | 103808 | 26.84 | 2.214e-07 | 0.9547 |
chr13:42001942 | rs73181127 | - | T>C | 3370 | 17693 | 26.61 | 2.494e-07 | 0.9058 |
chr6:34787537 | rs115566179 | UHRF1BP1 | G>T | 3121 | 13479 | 26.45 | 2.707e-07 | 1.11 |
chr2:136398174 | rs12619365 | - | C>T | 14618 | 74516 | 26.29 | 2.943e-07 | 0.9497 |
chr2:136420690 | rs4954280 | - | A>G | 14621 | 74562 | 26.26 | 2.981e-07 | 0.9497 |
chr3:50108792 | rs3774734 | RBM6 | A>C | 39061 | 182637 | 26.2 | 3.073e-07 | 1.039 |
chr3:50144951 | rs1061474 | RBM5 | C>T | 38278 | 178879 | 26.13 | 3.195e-07 | 1.039 |
chr2:136439090 | rs313518 | - | C>T | 14626 | 74523 | 26.1 | 3.234e-07 | 0.9499 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr9:22098574 | rs4977574 | - | A>G | 44166 | 171176 | 111.2 | 5.27e-26 | 1.082 |
chr9:22096055 | rs10757274 | - | A>G | 44350 | 171951 | 110.3 | 8.558e-26 | 1.082 |
chr9:22125347 | rs1333048 | - | A>C | 45281 | 175905 | 106.9 | 4.708e-25 | 1.081 |
chr9:22124477 | rs10757278 | - | A>G | 43745 | 169693 | 104.8 | 1.343e-24 | 1.08 |
chr9:22088260 | rs10757272 | - | C>T | 44241 | 171736 | 103.9 | 2.116e-24 | 1.08 |
chr9:22125503 | rs1333049 | - | G>C | 43749 | 169750 | 100.8 | 1.043e-23 | 1.078 |
chr6:161010118 | rs10455872 | LPA | A>G | 7324 | 26354 | 81.66 | 1.617e-19 | 1.132 |
chr6:160997118 | rs74617384 | LPA | A>T | 7145 | 25689 | 80.77 | 2.538e-19 | 1.133 |
chr6:160608804 | rs16891156 | SLC22A2 | A>C | 2484 | 8243 | 75.25 | 4.152e-18 | 1.223 |
chr9:22115959 | rs2383207 | - | G>A | 40947 | 170957 | 72.18 | 1.964e-17 | 0.9381 |
chr9:22083404 | rs1333040 | - | T>C | 35413 | 148305 | 67.39 | 2.226e-16 | 0.9391 |
chr9:22081850 | rs6475606 | - | C>T | 44982 | 176157 | 66.09 | 4.315e-16 | 1.063 |
chr9:22003223 | rs3217992 | AL359922.1 | C>T | 33194 | 128812 | 65.58 | 5.579e-16 | 1.065 |
chr9:22068652 | rs4977756 | - | A>G | 34032 | 142223 | 55.96 | 7.381e-14 | 0.9439 |
chr9:22029445 | rs10965215 | AL359922.1 | G>A | 42767 | 167686 | 53.92 | 2.09e-13 | 1.057 |
chr6:160848743 | rs9457925 | SLC22A3 | G>A | 1865 | 6278 | 48.34 | 3.581e-12 | 1.203 |
chr6:160922870 | rs117733303 | - | A>G | 1867 | 6311 | 46.16 | 1.088e-11 | 1.198 |
chr9:22053687 | rs10965219 | - | A>G | 44183 | 173844 | 46.0 | 1.182e-11 | 1.052 |
chr15:48426484 | rs1426654 | SLC24A5 | A>G | 1995 | 9487 | 45.75 | 1.344e-11 | 0.845 |
chr6:160961137 | rs3798220 | LPA | T>C | 1833 | 6192 | 45.55 | 1.49e-11 | 1.198 |
chr9:22096055 | rs10757274 | - | A>G | 41906 | 163532 | 95.07 | 1.836e-22 | 1.078 |
chr9:22098574 | rs4977574 | - | A>G | 41780 | 163005 | 94.99 | 1.91e-22 | 1.078 |
chr9:22125347 | rs1333048 | - | A>C | 42660 | 166793 | 91.66 | 1.028e-21 | 1.077 |
chr9:22088260 | rs10757272 | - | C>T | 41609 | 162517 | 89.81 | 2.628e-21 | 1.076 |
chr9:22125503 | rs1333049 | - | G>C | 41350 | 161373 | 89.76 | 2.687e-21 | 1.076 |
chr9:22124477 | rs10757278 | - | A>G | 41359 | 161486 | 89.72 | 2.744e-21 | 1.076 |
chr6:161010118 | rs10455872 | LPA | A>G | 7223 | 25995 | 86.96 | 1.107e-20 | 1.138 |
chr6:160997118 | rs74617384 | LPA | A>T | 7045 | 25335 | 85.9 | 1.891e-20 | 1.139 |
chr9:22115959 | rs2383207 | - | G>A | 39224 | 164942 | 82.75 | 9.308e-20 | 0.9319 |
chr9:22081850 | rs6475606 | - | C>T | 41279 | 161620 | 78.9 | 6.55e-19 | 1.071 |
chr9:22083404 | rs1333040 | - | T>C | 33379 | 140581 | 68.15 | 1.513e-16 | 0.9369 |
chr6:160608804 | rs16891156 | SLC22A2 | A>C | 1968 | 6545 | 60.78 | 6.374e-15 | 1.224 |
chr6:160848743 | rs9457925 | SLC22A3 | G>A | 1805 | 5961 | 59.53 | 1.202e-14 | 1.233 |
chr6:160922870 | rs117733303 | - | A>G | 1796 | 5943 | 58.02 | 2.592e-14 | 1.23 |
chr9:22003223 | rs3217992 | AL359922.1 | C>T | 31246 | 121987 | 57.5 | 3.382e-14 | 1.063 |
chr6:160961137 | rs3798220 | LPA | T>C | 1772 | 5866 | 56.92 | 4.535e-14 | 1.229 |
chr9:22068652 | rs4977756 | - | A>G | 32538 | 136574 | 52.73 | 3.833e-13 | 0.9441 |
chr9:21974218 | rs3731239 | AL359922.1 | A>G | 29494 | 123949 | 47.76 | 4.808e-12 | 0.9457 |
chr9:22053687 | rs10965219 | - | A>G | 40660 | 160430 | 47.23 | 6.314e-12 | 1.055 |
chr9:22043926 | rs1412829 | - | A>G | 34192 | 143111 | 46.78 | 7.935e-12 | 0.9476 |