Statistics
| Case | Control |
|---|---|
| 601 | 459593 |
Phenotype Definition
An anomalous structure of the periosteum, i.e., of the membrane that covers the outer surface of bones. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr3:45987980 | rs2234355 | FYCO1 | G>A | 38 | 10285 | 42.7 | 6.385e-11 | 2.805 |
| chr15:49737696 | rs8031680 | FAM227B | G>A | 45 | 13836 | 38.17 | 6.471e-10 | 2.478 |
| chr15:45556163 | rs8023604 | SLC28A2 | T>C | 41 | 12870 | 33.06 | 8.948e-09 | 2.422 |
| chr3:188327555 | rs7645635 | LPP | T>C | 44 | 14332 | 32.3 | 1.322e-08 | 2.333 |
| chr15:48309447 | rs16960493 | - | T>G | 88 | 36791 | 31.39 | 2.107e-08 | 1.84 |
| chr4:163907132 | rs28595382 | - | A>G | 52 | 18376 | 31.29 | 2.221e-08 | 2.167 |
| chr7:84866699 | rs2109504 | - | T>C | 38 | 11947 | 30.45 | 3.427e-08 | 2.414 |
| chr19:42965119 | rs11665935 | - | A>C | 179 | 90849 | 29.92 | 4.511e-08 | 1.548 |
| chr15:45695612 | rs1346265 | SPATA5L1 | C>T | 37 | 11633 | 29.68 | 5.088e-08 | 2.414 |
| chr19:39575987 | rs544041 | ACP7 | G>A | 34 | 10463 | 28.67 | 8.569e-08 | 2.463 |
| chr6:134358890 | rs6907633 | SLC2A12 | G>A | 88 | 37826 | 28.54 | 9.192e-08 | 1.79 |
| chr3:73713641 | rs907337 | - | T>C | 43 | 14576 | 28.46 | 9.553e-08 | 2.24 |
| chr10:18287814 | rs11818989 | SLC39A12 | T>G | 62 | 24054 | 28.2 | 1.096e-07 | 1.972 |
| chr13:31074486 | rs7326905 | HMGB1 | G>A | 34 | 10575 | 28.1 | 1.154e-07 | 2.442 |
| chr15:45694768 | rs1834686 | SPATA5L1 | G>T | 33 | 10186 | 27.75 | 1.382e-07 | 2.459 |
| chr16:1135797 | rs28379464 | - | C>T | 130 | 62570 | 27.09 | 1.942e-07 | 1.611 |
| chr2:97257528 | rs10183164 | - | A>G | 61 | 23832 | 27.05 | 1.987e-07 | 1.955 |
| chr16:82056468 | rs74029358 | - | A>G | 64 | 25412 | 27.0 | 2.036e-07 | 1.925 |
| chr10:14813860 | rs2768713 | FAM107B | A>G | 67 | 26995 | 26.9 | 2.146e-07 | 1.897 |
| chr10:111855748 | rs10400168 | ADD3 | C>A | 40 | 13484 | 26.81 | 2.25e-07 | 2.249 |
| chr6:42715323 | rs16896053 | BICRAL | C>T | 291 | 171197 | 24.83 | 6.255e-07 | 1.398 |
| chr16:85834818 | Affx-13376832 | COX4I1 | G>A | 99 | 47586 | 22.82 | 1.777e-06 | 1.643 |
| chr16:85821629 | rs74032013 | EMC8 | T>C | 99 | 47613 | 22.71 | 1.88e-06 | 1.641 |
| chr16:85832292 | rs11648858 | EMC8 | C>G | 94 | 45161 | 21.84 | 2.963e-06 | 1.645 |
| chr23:23775001 | rs72620454 | ACOT9 | G>A | 30 | 10412 | 21.71 | 3.165e-06 | 2.32 |
| chr16:85827080 | rs11644720 | EMC8 | T>C | 96 | 46462 | 21.43 | 3.667e-06 | 1.629 |
| chr5:73331784 | rs285600 | - | A>G | 47 | 18596 | 21.41 | 3.715e-06 | 1.967 |
| chr11:122590559 | rs79972088 | UBASH3B | C>T | 29 | 9779 | 20.66 | 5.473e-06 | 2.297 |
| chr3:146524722 | rs16858910 | - | T>C | 91 | 43825 | 20.62 | 5.608e-06 | 1.633 |
| chr9:7953253 | rs10815728 | - | C>T | 87 | 41814 | 20.42 | 6.221e-06 | 1.646 |
| chr19:39918351 | rs78287148 | PLEKHG2 | C>T | 34 | 12402 | 19.74 | 8.883e-06 | 2.129 |
| chr3:146537789 | rs12632326 | - | A>G | 99 | 49121 | 19.68 | 9.135e-06 | 1.587 |
| chr16:57822932 | rs78064555 | KIFC3 | G>C | 32 | 11410 | 19.63 | 9.395e-06 | 2.171 |
| chr10:10574494 | rs10905734 | - | C>T | 647 | 435516 | 19.62 | 9.439e-06 | 1.292 |
| chr3:69738461 | rs76328915 | - | G>A | 38 | 14429 | 19.61 | 9.508e-06 | 2.045 |
| chr5:9934655 | rs72734865 | - | A>G | 254 | 151521 | 19.36 | 1.085e-05 | 1.363 |
| chr9:133319473 | rs11244367 | - | T>G | 71 | 32779 | 19.27 | 1.136e-05 | 1.701 |
| chr23:23788125 | rs12689254 | - | G>A | 29 | 10444 | 18.96 | 1.334e-05 | 2.229 |
| chr14:42170021 | rs79033448 | LRFN5 | T>C | 30 | 10652 | 18.59 | 1.618e-05 | 2.178 |
| chr11:115941605 | rs112019166 | - | T>C | 44 | 17873 | 18.54 | 1.663e-05 | 1.917 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:42715323 | rs16896053 | BICRAL | C>T | 291 | 29454 | 25.31 | 4.89e-07 | 1.404 |
| chr23:23775001 | rs72620454 | ACOT9 | G>A | 30 | 1852 | 21.83 | 2.983e-06 | 2.337 |
| chr11:122590559 | rs79972088 | UBASH3B | C>T | 29 | 1657 | 21.38 | 3.767e-06 | 2.342 |
| chr16:85821629 | rs74032013 | EMC8 | T>C | 99 | 8354 | 20.97 | 4.667e-06 | 1.614 |
| chr16:85834818 | Affx-13376832 | COX4I1 | G>A | 99 | 8380 | 20.73 | 5.301e-06 | 1.609 |
| chr3:69738461 | rs76328915 | - | G>A | 38 | 2435 | 20.71 | 5.341e-06 | 2.094 |
| chr3:146524722 | rs16858910 | - | T>C | 91 | 7561 | 20.52 | 5.912e-06 | 1.635 |
| chr5:73331784 | rs285600 | - | A>G | 47 | 3246 | 20.45 | 6.134e-06 | 1.945 |
| chr9:133319473 | rs11244367 | - | T>G | 71 | 5573 | 20.28 | 6.701e-06 | 1.729 |
| chr19:39918351 | rs78287148 | PLEKHG2 | C>T | 34 | 2114 | 20.2 | 6.971e-06 | 2.158 |
| chr10:78944763 | rs11596909 | KCNMA1 | G>A | 54 | 3949 | 19.77 | 8.746e-06 | 1.847 |
| chr16:85827080 | rs11644720 | EMC8 | T>C | 96 | 8171 | 19.57 | 9.723e-06 | 1.598 |
| chr3:146537789 | rs12632326 | - | A>G | 99 | 8484 | 19.48 | 1.016e-05 | 1.587 |
| chr16:85832292 | rs11648858 | EMC8 | C>G | 94 | 7987 | 19.45 | 1.031e-05 | 1.604 |
| chr10:10574494 | rs10905734 | - | C>T | 647 | 75230 | 19.44 | 1.037e-05 | 1.291 |
| chr14:42170021 | rs79033448 | LRFN5 | T>C | 30 | 1808 | 19.22 | 1.167e-05 | 2.217 |
| chr23:23788125 | rs12689254 | - | G>A | 29 | 1865 | 18.89 | 1.382e-05 | 2.236 |
| chr7:123276611 | rs118072245 | ASB15 | C>T | 33 | 2074 | 18.88 | 1.394e-05 | 2.127 |
| chr16:57822932 | rs78064555 | KIFC3 | G>C | 32 | 1991 | 18.82 | 1.439e-05 | 2.148 |
| chr5:9934655 | rs72734865 | - | A>G | 254 | 26251 | 18.75 | 1.489e-05 | 1.358 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|
| ID | Name | Top Correlation |
|---|