Statistics
| Case | Control |
|---|---|
| 2979 | 457215 |
Phenotype Definition
A closed sac located in the spleen. [HPO:probinson, PMID:24794024]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr3:38051211 | rs75495843 | PLCD1 | G>A | 263 | 28745 | 33.97 | 5.585e-09 | 1.443 |
| chr14:75699566 | rs60699541 | - | C>G | 1426 | 194977 | 29.2 | 6.518e-08 | 1.177 |
| chr5:1315660 | rs4975616 | - | A>G | 2422 | 408394 | 26.5 | 2.64e-07 | 0.8745 |
| chr14:75572265 | rs96358 | ZC2HC1C | G>A | 2543 | 366028 | 24.75 | 6.51e-07 | 1.137 |
| chr5:33951693 | rs16891982 | SLC45A2 | G>C | 331 | 66727 | 23.79 | 1.072e-06 | 0.7593 |
| chr7:138317237 | rs28617498 | SVOPL | G>A | 52 | 15596 | 23.49 | 1.257e-06 | 0.5149 |
| chr6:31800868 | rs2471980 | - | G>C | 1888 | 321516 | 22.82 | 1.775e-06 | 0.8762 |
| chr4:135608367 | rs75890193 | - | T>C | 104 | 10179 | 22.81 | 1.788e-06 | 1.601 |
| chr5:1322087 | rs401681 | CLPTM1L | C>T | 2529 | 423139 | 22.65 | 1.946e-06 | 0.8841 |
| chr9:109538577 | rs7858184 | - | T>G | 938 | 126521 | 22.61 | 1.98e-06 | 1.184 |
| chr4:108094603 | rs72667821 | DKK2 | C>T | 318 | 38142 | 22.46 | 2.143e-06 | 1.314 |
| chr14:75459633 | rs175016 | - | C>T | 3097 | 453873 | 22.24 | 2.4e-06 | 1.128 |
| chr14:75701221 | rs4899554 | - | C>T | 1345 | 186667 | 22.08 | 2.61e-06 | 1.156 |
| chr14:75690868 | rs4903296 | - | T>C | 1362 | 189208 | 21.72 | 3.153e-06 | 1.154 |
| chr14:75538217 | rs3742778 | ZC2HC1C | G>T | 2736 | 452709 | 21.57 | 3.417e-06 | 0.8873 |
| chr14:75697062 | rs6574214 | - | A>G | 1876 | 266838 | 21.55 | 3.445e-06 | 1.137 |
| chr5:85393840 | rs72772174 | - | A>G | 316 | 38102 | 21.47 | 3.593e-06 | 1.307 |
| chr14:75626042 | rs910316 | TMED10 | A>C | 2771 | 459258 | 21.2 | 4.132e-06 | 0.8889 |
| chr10:134539299 | rs2767454 | INPP5A | C>G | 472 | 89849 | 21.05 | 4.482e-06 | 0.8027 |
| chr1:217641603 | rs76751983 | GPATCH2 | C>T | 181 | 20103 | 20.94 | 4.735e-06 | 1.412 |
| chr14:75699566 | rs60699541 | - | C>G | 1381 | 185609 | 29.61 | 5.277e-08 | 1.182 |
| chr5:1315660 | rs4975616 | - | A>G | 2314 | 384912 | 25.76 | 3.873e-07 | 0.8735 |
| chr3:38051211 | rs75495843 | PLCD1 | G>A | 247 | 27610 | 25.6 | 4.2e-07 | 1.389 |
| chr14:75697062 | rs6574214 | - | A>G | 1780 | 247001 | 25.13 | 5.371e-07 | 1.153 |
| chr5:1322087 | rs401681 | CLPTM1L | C>T | 2425 | 401073 | 23.47 | 1.27e-06 | 0.8797 |
| chr14:75572265 | rs96358 | ZC2HC1C | G>A | 2458 | 349188 | 23.39 | 1.326e-06 | 1.136 |
| chr13:74871188 | rs9543560 | - | C>A | 1042 | 139360 | 22.7 | 1.89e-06 | 1.177 |
| chr21:32497674 | rs2833283 | TIAM1 | A>C | 249 | 28388 | 22.22 | 2.429e-06 | 1.357 |
| chr4:108094603 | rs72667821 | DKK2 | C>T | 314 | 37138 | 22.16 | 2.515e-06 | 1.314 |
| chr14:75459633 | rs175016 | - | C>T | 2967 | 428278 | 21.75 | 3.109e-06 | 1.13 |
| chr14:75538217 | rs3742778 | ZC2HC1C | G>T | 2626 | 428554 | 21.74 | 3.117e-06 | 0.8846 |
| chr14:75626042 | rs910316 | TMED10 | A>C | 2656 | 434781 | 21.64 | 3.286e-06 | 0.8855 |
| chr6:31800868 | rs2471980 | - | G>C | 1771 | 297351 | 21.53 | 3.477e-06 | 0.8764 |
| chr14:75532941 | rs7156328 | ACYP1 | T>C | 2649 | 434230 | 21.5 | 3.537e-06 | 0.8857 |
| chr14:75574087 | rs10146482 | ZC2HC1C | C>T | 2646 | 434560 | 21.39 | 3.743e-06 | 0.8859 |
| chr14:75590822 | rs8017642 | NEK9 | G>A | 2654 | 434477 | 21.08 | 4.402e-06 | 0.8868 |
| chr4:135608367 | rs75890193 | - | T>C | 101 | 9879 | 20.85 | 4.961e-06 | 1.579 |
| chr23:93056170 | rs62597059 | - | G>C | 787 | 105201 | 20.74 | 5.265e-06 | 1.196 |
| chr14:75671659 | rs6574212 | - | A>G | 2657 | 434994 | 20.43 | 6.178e-06 | 0.8884 |
| chr9:109538577 | rs7858184 | - | T>G | 910 | 121747 | 20.2 | 6.962e-06 | 1.176 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr3:66430870 | Affx-22621685 | SLC25A26 | G>A | 493 | 921 | 26.55 | 2.563e-07 | 1.347 |
| chr6:32109979 | rs204999 | - | A>G | 1689 | 4689 | 25.59 | 4.232e-07 | 0.843 |
| chr6:31851234 | rs652888 | EHMT2 | A>G | 1279 | 3630 | 25.46 | 4.514e-07 | 0.8302 |
| chr6:29546799 | rs1233396 | GABBR1 | G>A | 711 | 2146 | 25.37 | 4.725e-07 | 0.7923 |
| chr6:29548089 | rs926552 | GABBR1 | G>A | 712 | 2146 | 25.01 | 5.709e-07 | 0.7937 |
| chr6:32059867 | rs1150753 | TNXB | A>G | 697 | 2093 | 23.75 | 1.099e-06 | 0.7967 |
| chr6:32080191 | rs1269852 | TNXB | G>C | 692 | 2080 | 23.68 | 1.14e-06 | 0.7964 |
| chr6:32064726 | rs1150752 | TNXB | T>C | 698 | 2095 | 23.61 | 1.177e-06 | 0.7973 |
| chr6:32155581 | rs204993 | PBX2 | A>G | 1746 | 4801 | 23.17 | 1.48e-06 | 0.8513 |
| chr6:32156908 | rs204992 | PBX2 | G>A | 1388 | 3885 | 23.08 | 1.555e-06 | 0.8416 |
| chr6:31940897 | rs389884 | STK19 | A>G | 699 | 2095 | 23.03 | 1.595e-06 | 0.7996 |
| chr6:31918860 | rs1270942 | AL645922.1 | A>G | 699 | 2092 | 22.94 | 1.675e-06 | 0.8 |
| chr2:219755011 | rs121908120 | WNT10A | T>A | 101 | 417 | 22.7 | 1.894e-06 | 0.5899 |
| chr6:31870326 | rs558702 | C2 | G>A | 697 | 2082 | 22.67 | 1.926e-06 | 0.8008 |
| chr6:32117971 | rs3134608 | PRRT1 | T>G | 1269 | 3574 | 22.45 | 2.162e-06 | 0.8392 |
| chr6:31340075 | rs2844559 | - | C>T | 781 | 2305 | 22.4 | 2.218e-06 | 0.8099 |
| chr6:32154998 | rs204994 | PBX2 | C>T | 1388 | 3887 | 22.38 | 2.236e-06 | 0.8438 |
| chr6:31892484 | rs497309 | C2 | A>C | 699 | 2085 | 22.38 | 2.234e-06 | 0.8021 |
| chr6:32158319 | rs176095 | - | A>G | 1390 | 3885 | 22.3 | 2.331e-06 | 0.8442 |
| chr6:32145993 | rs3134946 | - | C>G | 1276 | 3588 | 22.11 | 2.579e-06 | 0.8406 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: L720 | Epidermal cyst | 9/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: C252 | Tail of pancreas | 0/20 |