0030846

Case	Control
19172	441022

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr1:10833232	rs58064215	CASZ1	G>C	13272	283958	121.4	3.184e-28	1.127
chr15:48426484	rs1426654	SLC24A5	A>G	789	26737	114.2	1.191e-26	0.6788
chr15:48392165	rs1834640	-	A>G	959	30665	99.49	1.967e-23	0.7192
chr8:145639681	rs1871534	SLC39A4	G>C	495	17650	91.67	1.023e-21	0.6468
chr16:88808743	Affx-13429237	PIEZO1	G>A	5702	117874	84.87	3.182e-20	1.144
chr16:88744470	rs8048897	SNAI3	G>T	4019	81094	82.76	9.25e-20	1.167
chr16:88792047	Affx-13428879	PIEZO1	G>A	5350	110313	82.32	1.156e-19	1.146
chr16:88783521	Affx-13428745	PIEZO1	C>T	4770	97594	81.53	1.727e-19	1.153
chr8:10557760	rs57041981	RP1L1	A>G	458	16190	81.3	1.943e-19	0.6528
chr16:88776297	rs4390574	CTU2	C>T	4976	102500	76.8	1.889e-18	1.145
chr9:140957557	rs11137360	CACNA1B	A>G	620	20386	75.3	4.039e-18	0.7014
chr19:42393286	rs717225	ARHGEF1	A>G	654	21289	74.72	5.433e-18	0.7087
chr16:88787704	rs8043924	PIEZO1	C>G	5542	115243	73.28	1.123e-17	1.135
chr1:159174683	rs2814778	ACKR1	T>C	566	18811	72.92	1.347e-17	0.6943
chr17:58508582	rs8071181	C17orf64	G>A	429	14988	71.88	2.289e-17	0.6607
chr16:88783449	rs8057031	PIEZO1	G>C	18475	408966	71.64	2.581e-17	1.09
chr9:137925543	rs7027926	-	G>A	479	16341	71.07	3.454e-17	0.6766
chr16:88807896	rs7404939	PIEZO1	G>A	5548	115629	70.14	5.524e-17	1.132
chr1:10831218	rs172228	CASZ1	G>C	7170	151854	68.92	1.028e-16	1.117
chr12:3417813	rs729914	-	G>T	459	15628	67.28	2.356e-16	0.6782
chr1:10833232	rs58064215	CASZ1	G>C	12194	252429	180.5	3.701e-41	1.163
chr1:10831218	rs172228	CASZ1	G>C	6531	131493	129.9	4.224e-30	1.172
chr1:10824329	rs6540950	CASZ1	C>T	7456	155241	86.97	1.1e-20	1.131
chr16:88776297	rs4390574	CTU2	C>T	4681	94655	83.56	6.175e-20	1.157
chr16:88807896	rs7404939	PIEZO1	G>A	5148	104824	82.55	1.031e-19	1.149
chr16:88783521	Affx-13428745	PIEZO1	C>T	4533	91590	81.45	1.799e-19	1.157
chr16:88808743	Affx-13429237	PIEZO1	G>A	5479	112395	79.34	5.227e-19	1.142
chr16:88792047	Affx-13428879	PIEZO1	G>A	5069	103579	77.5	1.324e-18	1.145
chr16:88787704	rs8043924	PIEZO1	C>G	5199	106475	76.22	2.536e-18	1.143
chr16:88744470	rs8048897	SNAI3	G>T	3859	77585	73.2	1.169e-17	1.16
chr16:88804734	rs7184427	PIEZO1	G>A	6169	128626	65.38	6.178e-16	1.123
chr16:88853729	Affx-13430005	-	T>C	17758	390089	64.52	9.548e-16	1.088
chr16:88783449	rs8057031	PIEZO1	G>C	17727	389707	62.79	2.304e-15	1.087
chr2:68435280	rs7572554	AC017083.3	T>C	12419	302978	62.05	3.341e-15	0.9159
chr2:68409037	rs1868402	AC017083.3	A>G	10325	254054	61.58	4.245e-15	0.9119
chr2:68457573	rs12468533	AC017083.3	T>C	12441	303202	61.16	5.272e-15	0.9166
chr2:68385097	rs2044693	AC017083.3	G>A	12917	314132	59.9	9.99e-15	0.9182
chr16:88844433	rs2968482	PIEZO1	T>C	10716	262769	59.9	9.955e-15	0.914
chr16:88719980	rs8046018	MVD	G>T	5537	115918	54.16	1.846e-13	1.116
chr5:127548955	rs36694	-	A>C	10487	226521	52.96	3.399e-13	1.089

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr15:48426484	rs1426654	SLC24A5	A>G	789	4108	110.2	9.063e-26	0.6639
chr5:33951693	rs16891982	SLC45A2	G>C	2435	10641	108.1	2.557e-25	0.786
chr15:48392165	rs1834640	-	A>G	959	4793	107.6	3.318e-25	0.6909
chr8:145639681	rs1871534	SLC39A4	G>C	495	2825	105.8	8.171e-25	0.6068
chr19:42393286	rs717225	ARHGEF1	A>G	654	3480	101.5	7.246e-24	0.6505
chr8:10557760	rs57041981	RP1L1	A>G	458	2574	91.46	1.141e-21	0.6167
chr1:10833232	rs58064215	CASZ1	G>C	13272	42809	91.05	1.398e-21	1.122
chr19:42392441	rs16975619	ARHGEF1	T>C	600	3160	88.18	5.968e-21	0.6579
chr23:102201216	rs725570	-	A>G	631	3039	86.44	1.44e-20	0.6647
chr1:159174683	rs2814778	ACKR1	T>C	566	3000	86.0	1.798e-20	0.6537
chr9:140957557	rs11137360	CACNA1B	A>G	620	3215	84.42	4.001e-20	0.6678
chr19:42391425	rs28521795	ARHGEF1	G>A	566	2987	84.0	4.936e-20	0.6568
chr5:33958959	rs28777	SLC45A2	A>C	2087	9037	83.99	4.963e-20	0.7958
chr9:137925543	rs7027926	-	G>A	479	2615	83.79	5.494e-20	0.635
chr19:42392310	rs2288509	ARHGEF1	C>T	523	2795	82.05	1.328e-19	0.6496
chr23:64367019	rs7064929	-	G>A	575	2786	81.16	2.082e-19	0.6611
chr17:58508582	rs8071181	C17orf64	G>A	429	2381	80.95	2.31e-19	0.6247
chr23:71628912	rs3012642	AL133500.1	A>G	743	3407	77.84	1.118e-18	0.6978
chr10:127291027	rs927957	TEX36	C>T	764	3754	76.89	1.812e-18	0.7048
chr23:106146349	rs5962774	MORC4	T>C	316	1724	76.0	2.839e-18	0.5884
chr1:10833232	rs58064215	CASZ1	G>C	12194	37518	150.7	1.193e-34	1.167
chr1:10831218	rs172228	CASZ1	G>C	6531	19512	109.1	1.56e-25	1.177
chr1:10824329	rs6540950	CASZ1	C>T	7456	22967	79.63	4.514e-19	1.141
chr16:88776297	rs4390574	CTU2	C>T	4681	14083	67.56	2.04e-16	1.159
chr16:88807896	rs7404939	PIEZO1	G>A	5148	15630	64.52	9.571e-16	1.148
chr16:88783521	Affx-13428745	PIEZO1	C>T	4533	13655	64.19	1.13e-15	1.157
chr16:88744470	rs8048897	SNAI3	G>T	3859	11504	61.97	3.486e-15	1.167
chr16:88792047	Affx-13428879	PIEZO1	G>A	5069	15440	61.1	5.428e-15	1.145
chr16:88787704	rs8043924	PIEZO1	C>G	5199	15862	60.61	6.962e-15	1.143
chr16:88808743	Affx-13429237	PIEZO1	G>A	5479	16791	60.24	8.386e-15	1.139
chr2:68435280	rs7572554	AC017083.3	T>C	12419	45234	54.89	1.275e-13	0.9124
chr16:88853729	Affx-13430005	-	T>C	17758	58071	54.73	1.383e-13	1.09
chr2:68457573	rs12468533	AC017083.3	T>C	12441	45260	53.18	3.047e-13	0.9138
chr2:68409037	rs1868402	AC017083.3	A>G	10325	37853	50.1	1.461e-12	0.9119
chr2:68385097	rs2044693	AC017083.3	G>A	12917	46834	49.79	1.712e-12	0.9172
chr16:88804734	rs7184427	PIEZO1	G>A	6169	19121	49.59	1.895e-12	1.12
chr16:88844433	rs2968482	PIEZO1	T>C	10716	39135	48.21	3.835e-12	0.9144
chr16:88719980	rs8046018	MVD	G>T	5537	17182	47.95	4.364e-12	1.122
chr3:128290848	rs2713587	-	A>G	19011	62590	46.8	7.86e-12	1.083
chr5:127548955	rs36694	-	A>C	10487	33697	44.82	2.165e-11	1.092

Location

SNP

Gene

Ref>Alt

Alt in Case

Alt in Control

Chi-square

P-value

Odds ratio

chr15:48426484

rs1426654

SLC24A5

A>G

789

4108

110.2

9.063e-26

0.6639

chr5:33951693

rs16891982

SLC45A2

G>C

2435

10641

108.1

2.557e-25

0.786

chr15:48392165

rs1834640

-

A>G

959

4793

107.6

3.318e-25

0.6909

chr8:145639681

rs1871534

SLC39A4

G>C

495

2825

105.8

8.171e-25

0.6068

chr19:42393286

rs717225

ARHGEF1

A>G

654

3480

101.5

7.246e-24

0.6505

chr8:10557760

rs57041981

RP1L1

A>G

458

2574

91.46

1.141e-21

0.6167

chr1:10833232

rs58064215

CASZ1

G>C

13272

42809

91.05

1.398e-21

1.122

chr19:42392441

rs16975619

ARHGEF1

T>C

600

3160

88.18

5.968e-21

0.6579

chr23:102201216

rs725570

-

A>G

631

3039

86.44

1.44e-20

0.6647

chr1:159174683

rs2814778

ACKR1

T>C

566

3000

86.0

1.798e-20

0.6537

chr9:140957557

rs11137360

CACNA1B

A>G

620

3215

84.42

4.001e-20

0.6678

chr19:42391425

rs28521795

ARHGEF1

G>A

566

2987

84.0

4.936e-20

0.6568

chr5:33958959

rs28777

SLC45A2

A>C

2087

9037

83.99

4.963e-20

0.7958

chr9:137925543

rs7027926

-

G>A

479

2615

83.79

5.494e-20

0.635

chr19:42392310

rs2288509

ARHGEF1

C>T

523

2795

82.05

1.328e-19

0.6496

chr23:64367019

rs7064929

-

G>A

575

2786

81.16

2.082e-19

0.6611

chr17:58508582

rs8071181

C17orf64

G>A

429

2381

80.95

2.31e-19

0.6247

chr23:71628912

rs3012642

AL133500.1

A>G

743

3407

77.84

1.118e-18

0.6978

chr10:127291027

rs927957

TEX36

C>T

764

3754

76.89

1.812e-18

0.7048

chr23:106146349

rs5962774

MORC4

T>C

316

1724

76.0

2.839e-18

0.5884

chr1:10833232

rs58064215

CASZ1

G>C

12194

37518

150.7

1.193e-34

1.167

chr1:10831218

rs172228

CASZ1

G>C

6531

19512

109.1

1.56e-25

1.177

chr1:10824329

rs6540950

CASZ1

C>T

7456

22967

79.63

4.514e-19

1.141

chr16:88776297

rs4390574

CTU2

C>T

4681

14083

67.56

2.04e-16

1.159

chr16:88807896

rs7404939

PIEZO1

G>A

5148

15630

64.52

9.571e-16

1.148

chr16:88783521

Affx-13428745

PIEZO1

C>T

4533

13655

64.19

1.13e-15

1.157

chr16:88744470

rs8048897

SNAI3

G>T

3859

11504

61.97

3.486e-15

1.167

chr16:88792047

Affx-13428879

PIEZO1

G>A

5069

15440

61.1

5.428e-15

1.145

chr16:88787704

rs8043924

PIEZO1

C>G

5199

15862

60.61

6.962e-15

1.143

chr16:88808743

Affx-13429237

PIEZO1

G>A

5479

16791

60.24

8.386e-15

1.139

chr2:68435280

rs7572554

AC017083.3

T>C

12419

45234

54.89

1.275e-13

0.9124

chr16:88853729

Affx-13430005

-

T>C

17758

58071

54.73

1.383e-13

1.09

chr2:68457573

rs12468533

AC017083.3

T>C

12441

45260

53.18

3.047e-13

0.9138

chr2:68409037

rs1868402

AC017083.3

A>G

10325

37853

50.1

1.461e-12

0.9119

chr2:68385097

rs2044693

AC017083.3

G>A

12917

46834

49.79

1.712e-12

0.9172

chr16:88804734

rs7184427

PIEZO1

G>A

6169

19121

49.59

1.895e-12

1.12

chr16:88844433

rs2968482

PIEZO1

T>C

10716

39135

48.21

3.835e-12

0.9144

chr16:88719980

rs8046018

MVD

G>T

5537

17182

47.95

4.364e-12

1.122

chr3:128290848

rs2713587

-

A>G

19011

62590

46.8

7.86e-12

1.083

chr5:127548955

rs36694

-

A>C

10487

33697

44.82

2.165e-11

1.092

ID	Name	Top Correlation
ICD-10: I728	Aneurysm of other specified arteries	0/20
ICD-10: I81	Portal vein thrombosis	0/20
ICD-10: I830	Varicose veins of lower extremities with ulcer	0/20
ICD-10: I831	Varicose veins of lower extremities with inflammation	0/20
ICD-10: I832	Varicose veins of lower extremities with both ulcer and inflammation	0/20
ICD-10: I872	Venous insufficiency (chronic) (peripheral)	0/20
ICD-10: I878	Other specified disorders of veins	0/20
ICD-10: R072	Precordial pain	0/20

Abnormality of venous physiology

0030846

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information

Associated Diseases ^ⓘ

Abnormality of venous physiology

0030846

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ