Statistics
| Case | Control |
|---|---|
| 375 | 459819 |
Phenotype Definition
An anomaly of the pulse pressure, which is defined as the systolic pressured minus the diastolic pressure. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr10:24694909 | rs17513725 | KIAA1217 | G>A | 275 | 256812 | 32.74 | 1.052e-08 | 1.532 |
| chr9:118720316 | rs117717315 | - | C>T | 34 | 17735 | 28.34 | 1.018e-07 | 2.468 |
| chr12:95906147 | rs71458597 | METAP2 | G>A | 82 | 58690 | 28.2 | 1.095e-07 | 1.842 |
| chr10:77576753 | rs117873064 | LRMDA | A>G | 36 | 19858 | 26.2 | 3.072e-07 | 2.337 |
| chr4:31090001 | rs78548360 | PCDH7 | G>A | 63 | 43340 | 24.74 | 6.566e-07 | 1.902 |
| chr16:88872229 | rs480727 | CDT1 | A>G | 222 | 360795 | 23.7 | 1.126e-06 | 0.6808 |
| chr10:77544651 | rs76519949 | LRMDA | A>G | 34 | 19252 | 23.2 | 1.461e-06 | 2.275 |
| chr6:14072545 | rs115994014 | - | C>T | 64 | 44875 | 22.54 | 2.057e-06 | 1.842 |
| chr9:118741536 | rs117897410 | - | T>C | 27 | 14216 | 22.33 | 2.292e-06 | 2.451 |
| chr10:114232089 | rs11195970 | VTI1A | T>C | 109 | 89127 | 22.19 | 2.474e-06 | 1.62 |
| chr4:2396293 | rs6814736 | ZFYVE28 | G>C | 134 | 115359 | 22.0 | 2.72e-06 | 1.556 |
| chr15:68317407 | rs17249287 | - | A>G | 251 | 244686 | 21.7 | 3.18e-06 | 1.428 |
| chr4:31076904 | rs73218819 | PCDH7 | A>G | 110 | 91004 | 21.27 | 3.997e-06 | 1.601 |
| chr7:155630045 | rs1151791 | - | T>G | 79 | 60419 | 21.13 | 4.297e-06 | 1.715 |
| chr4:2351551 | rs11737615 | ZFYVE28 | T>C | 126 | 108546 | 20.72 | 5.313e-06 | 1.553 |
| chr1:65699345 | rs12403808 | - | A>G | 33 | 19423 | 20.43 | 6.174e-06 | 2.192 |
| chr7:4647809 | rs80081644 | - | G>A | 46 | 30394 | 20.29 | 6.669e-06 | 1.959 |
| chr13:91126869 | rs11619126 | - | C>T | 29 | 16263 | 20.21 | 6.939e-06 | 2.288 |
| chr11:10830691 | rs1546164 | - | C>T | 32 | 18649 | 20.16 | 7.105e-06 | 2.205 |
| chr23:46546737 | rs5906255 | SLC9A7 | G>A | 50 | 38030 | 19.92 | 8.067e-06 | 1.919 |
| chr5:60866192 | rs6872620 | - | C>A | 36 | 18171 | 30.87 | 2.764e-08 | 2.503 |
| chr10:24694909 | rs17513725 | KIAA1217 | G>A | 269 | 246823 | 30.62 | 3.141e-08 | 1.52 |
| chr9:118720316 | rs117717315 | - | C>T | 34 | 17334 | 28.2 | 1.094e-07 | 2.465 |
| chr12:95906147 | rs71458597 | METAP2 | G>A | 82 | 57568 | 27.67 | 1.44e-07 | 1.834 |
| chr10:77576753 | rs117873064 | LRMDA | A>G | 36 | 19163 | 26.76 | 2.304e-07 | 2.358 |
| chr4:2351551 | rs11737615 | ZFYVE28 | T>C | 125 | 101271 | 24.74 | 6.576e-07 | 1.622 |
| chr4:31090001 | rs78548360 | PCDH7 | G>A | 63 | 42587 | 24.15 | 8.9e-07 | 1.89 |
| chr10:114232089 | rs11195970 | VTI1A | T>C | 108 | 84494 | 24.04 | 9.424e-07 | 1.657 |
| chr10:77544651 | rs76519949 | LRMDA | A>G | 34 | 18603 | 23.77 | 1.084e-06 | 2.299 |
| chr15:79238656 | rs77719589 | CTSH | C>T | 35 | 19664 | 22.85 | 1.756e-06 | 2.239 |
| chr9:118741536 | rs117897410 | - | T>C | 27 | 13826 | 22.5 | 2.098e-06 | 2.46 |
| chr1:203502968 | rs61828007 | - | A>G | 25 | 12341 | 22.36 | 2.255e-06 | 2.532 |
| chr20:54967893 | rs2236208 | CSTF1 | T>C | 23 | 11166 | 21.37 | 3.789e-06 | 2.572 |
| chr4:2396293 | rs6814736 | ZFYVE28 | G>C | 129 | 108403 | 21.06 | 4.441e-06 | 1.554 |
| chr18:67568317 | rs67660661 | CD226 | G>T | 194 | 178029 | 20.7 | 5.377e-06 | 1.459 |
| chr16:88872229 | rs480727 | CDT1 | A>G | 210 | 329630 | 20.39 | 6.314e-06 | 0.694 |
| chr9:113646117 | rs76887292 | LPAR1 | T>C | 81 | 62151 | 19.67 | 9.22e-06 | 1.676 |
| chr5:21031429 | rs13158052 | - | G>A | 65 | 46844 | 19.65 | 9.28e-06 | 1.765 |
| chr1:163815371 | rs781946 | - | G>A | 13 | 48849 | 19.15 | 1.206e-05 | 0.3139 |
| chr20:56579137 | rs6070334 | - | T>C | 291 | 288044 | 19.0 | 1.308e-05 | 1.384 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr5:60866192 | rs6872620 | - | C>A | 36 | 3273 | 32.07 | 1.485e-08 | 2.555 |
| chr10:24694909 | rs17513725 | KIAA1217 | G>A | 269 | 45318 | 30.67 | 3.06e-08 | 1.521 |
| chr9:118720316 | rs117717315 | - | C>T | 34 | 3198 | 27.73 | 1.394e-07 | 2.456 |
| chr12:95906147 | rs71458597 | METAP2 | G>A | 82 | 10618 | 27.14 | 1.892e-07 | 1.827 |
| chr10:77576753 | rs117873064 | LRMDA | A>G | 36 | 3520 | 26.59 | 2.511e-07 | 2.36 |
| chr4:31090001 | rs78548360 | PCDH7 | G>A | 63 | 7860 | 23.65 | 1.156e-06 | 1.882 |
| chr4:2351551 | rs11737615 | ZFYVE28 | T>C | 125 | 18772 | 23.63 | 1.165e-06 | 1.606 |
| chr10:114232089 | rs11195970 | VTI1A | T>C | 108 | 15594 | 23.46 | 1.276e-06 | 1.649 |
| chr10:77544651 | rs76519949 | LRMDA | A>G | 34 | 3428 | 23.42 | 1.302e-06 | 2.292 |
| chr9:118741536 | rs117897410 | - | T>C | 27 | 2508 | 23.01 | 1.608e-06 | 2.493 |
| chr15:79238656 | rs77719589 | CTSH | C>T | 35 | 3600 | 22.9 | 1.707e-06 | 2.248 |
| chr20:54967893 | rs2236208 | CSTF1 | T>C | 23 | 2007 | 22.27 | 2.369e-06 | 2.63 |
| chr1:203502968 | rs61828007 | - | A>G | 25 | 2277 | 21.96 | 2.78e-06 | 2.522 |
| chr4:2396293 | rs6814736 | ZFYVE28 | G>C | 129 | 19940 | 20.86 | 4.934e-06 | 1.553 |
| chr18:67568317 | rs67660661 | CD226 | G>T | 194 | 32858 | 20.02 | 7.671e-06 | 1.451 |
| chr9:113646117 | rs76887292 | LPAR1 | T>C | 81 | 11401 | 19.7 | 9.063e-06 | 1.679 |
| chr10:28201745 | rs184829476 | ARMC4 | G>A | 20 | 1749 | 19.24 | 1.152e-05 | 2.618 |
| chr23:46546737 | rs5906255 | SLC9A7 | G>A | 50 | 6719 | 19.23 | 1.16e-05 | 1.903 |
| chr20:56579137 | rs6070334 | - | T>C | 291 | 52858 | 19.2 | 1.18e-05 | 1.388 |
| chr5:21031429 | rs13158052 | - | G>A | 65 | 8653 | 19.16 | 1.202e-05 | 1.755 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: I672 | Cerebral atherosclerosis | 20/20 |
| ID | Name | Top Correlation |
|---|