Statistics
| Case | Control |
|---|---|
| 9653 | 450541 |
Phenotype Definition
The presence of tufts of 8-15 hairs that appear to emerge from a single follicular orifice. []
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr15:48426484 | rs1426654 | SLC24A5 | A>G | 353 | 27173 | 85.93 | 1.864e-20 | 0.609 |
| chr20:2315543 | rs6132532 | AL121899.2 | A>G | 762 | 48772 | 72.05 | 2.094e-17 | 0.73 |
| chr15:48392165 | rs1834640 | - | A>G | 466 | 31158 | 56.79 | 4.86e-14 | 0.7019 |
| chr6:170242949 | rs9396958 | - | T>C | 200 | 15914 | 55.02 | 1.191e-13 | 0.5919 |
| chr5:33951693 | rs16891982 | SLC45A2 | G>C | 1124 | 65934 | 54.08 | 1.927e-13 | 0.7968 |
| chr5:147863034 | rs9325101 | HTR4 | A>G | 225 | 16515 | 43.9 | 3.449e-11 | 0.6417 |
| chr5:33958959 | rs28777 | SLC45A2 | A>C | 960 | 56032 | 43.58 | 4.063e-11 | 0.8027 |
| chr15:73142636 | rs4777559 | - | C>T | 199 | 14787 | 41.13 | 1.426e-10 | 0.6338 |
| chr2:66725070 | rs12995572 | MEIS1 | G>C | 413 | 26738 | 41.01 | 1.513e-10 | 0.7265 |
| chr6:25918225 | rs80215559 | SLC17A2 | T>C | 1685 | 68699 | 39.97 | 2.577e-10 | 1.177 |
| chr6:170602429 | rs17860704 | DLL1 | T>C | 146 | 11572 | 39.49 | 3.296e-10 | 0.5949 |
| chr5:106908138 | rs163961 | EFNA5 | A>C | 479 | 30089 | 39.48 | 3.315e-10 | 0.7468 |
| chr10:108672251 | rs1572457 | SORCS1 | C>T | 146 | 11572 | 39.39 | 3.476e-10 | 0.5953 |
| chr10:111855748 | rs10400168 | ADD3 | C>A | 177 | 13347 | 38.85 | 4.58e-10 | 0.6254 |
| chr10:12267086 | rs10906102 | CDC123 | T>C | 558 | 34310 | 38.81 | 4.671e-10 | 0.7643 |
| chr2:136788139 | rs7584512 | - | A>G | 189 | 14020 | 38.69 | 4.976e-10 | 0.6352 |
| chr5:54280007 | rs1508890 | ESM1 | C>A | 262 | 18154 | 38.46 | 5.588e-10 | 0.6797 |
| chr3:122328753 | rs2173764 | PARP15 | A>G | 188 | 13931 | 38.34 | 5.947e-10 | 0.6358 |
| chr19:42391425 | rs28521795 | ARHGEF1 | G>A | 269 | 18553 | 38.29 | 6.11e-10 | 0.6837 |
| chr6:3185712 | rs7754077 | - | C>T | 267 | 18405 | 38.14 | 6.598e-10 | 0.6832 |
| chr6:25918225 | rs80215559 | SLC17A2 | T>C | 1669 | 68026 | 32.11 | 1.459e-08 | 1.158 |
| chr5:127548955 | rs36694 | - | A>C | 5298 | 231710 | 28.83 | 7.9e-08 | 1.092 |
| chr6:25842951 | rs1408272 | SLC17A3 | T>G | 1705 | 70179 | 28.68 | 8.542e-08 | 1.147 |
| chr5:127347013 | rs34145453 | - | A>G | 7427 | 329781 | 27.67 | 1.438e-07 | 1.082 |
| chr14:45194762 | rs229748 | - | A>G | 6281 | 309332 | 27.04 | 1.99e-07 | 0.9224 |
| chr7:152339892 | rs57333909 | - | G>A | 1946 | 81149 | 26.51 | 2.623e-07 | 1.133 |
| chr8:9742841 | rs7828229 | - | T>C | 4775 | 208888 | 26.42 | 2.744e-07 | 1.091 |
| chr5:127552590 | rs2546147 | - | A>G | 5297 | 232911 | 25.66 | 4.076e-07 | 1.086 |
| chr6:29961580 | rs9260973 | - | G>A | 2677 | 113941 | 25.47 | 4.499e-07 | 1.112 |
| chr6:30002793 | rs3121593 | - | C>G | 2730 | 116346 | 25.42 | 4.622e-07 | 1.111 |
| chr6:30030114 | rs9261269 | ZNRD1 | G>A | 2729 | 116447 | 24.73 | 6.602e-07 | 1.109 |
| chr6:30067681 | rs7763159 | - | G>A | 2671 | 113896 | 24.39 | 7.86e-07 | 1.11 |
| chr8:8569724 | rs883647 | - | G>A | 7112 | 347223 | 23.88 | 1.025e-06 | 0.9289 |
| chr2:38009280 | rs13404698 | - | A>G | 2200 | 113203 | 23.84 | 1.049e-06 | 0.8944 |
| chr6:27941387 | rs13214703 | - | T>C | 1924 | 80740 | 23.78 | 1.082e-06 | 1.126 |
| chr6:29934454 | rs3893259 | - | G>A | 2695 | 115181 | 23.39 | 1.325e-06 | 1.107 |
| chr6:29955199 | rs5025708 | - | T>G | 2537 | 108090 | 23.31 | 1.381e-06 | 1.11 |
| chr6:29935469 | rs9260761 | - | C>T | 2675 | 114472 | 22.69 | 1.905e-06 | 1.106 |
| chr6:29936135 | rs4959036 | - | T>G | 2689 | 115131 | 22.5 | 2.099e-06 | 1.105 |
| chr8:8123457 | rs951701 | - | C>G | 4739 | 209022 | 22.49 | 2.11e-06 | 1.084 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr4:116690684 | rs72679066 | - | A>C | 319 | 37 | 28.78 | 8.088e-08 | 0.3993 |
| chr1:3301586 | rs117381898 | PRDM16 | G>A | 365 | 40 | 27.04 | 1.99e-07 | 0.4238 |
| chr4:116134873 | rs72669504 | - | C>T | 291 | 34 | 27.01 | 2.026e-07 | 0.3961 |
| chr4:116482173 | rs72676111 | - | A>T | 316 | 36 | 26.84 | 2.212e-07 | 0.4071 |
| chr4:115980099 | rs72681457 | NDST4 | A>G | 297 | 34 | 25.45 | 4.55e-07 | 0.4067 |
| chr5:14910991 | rs56167416 | - | G>A | 850 | 73 | 25.26 | 4.998e-07 | 0.5336 |
| chr9:33520629 | rs10123277 | - | G>A | 4759 | 293 | 24.44 | 7.657e-07 | 0.6987 |
| chr3:14929123 | rs902448 | FGD5 | C>T | 5322 | 320 | 23.34 | 1.355e-06 | 0.71 |
| chr14:57415298 | rs709991 | - | A>G | 237 | 28 | 22.66 | 1.938e-06 | 0.3938 |
| chr3:11914075 | rs115405911 | - | C>T | 493 | 47 | 22.28 | 2.352e-06 | 0.485 |
| chr3:73256681 | rs77960282 | - | T>G | 328 | 35 | 22.16 | 2.504e-06 | 0.4364 |
| chr19:46347542 | rs10420834 | SYMPK | G>T | 1710 | 123 | 22.1 | 2.591e-06 | 0.627 |
| chr2:58764938 | rs4672245 | - | A>G | 450 | 44 | 21.76 | 3.088e-06 | 0.4779 |
| chr17:33008781 | rs76091907 | - | A>C | 216 | 26 | 21.72 | 3.156e-06 | 0.3885 |
| chr9:17896998 | rs4961610 | - | C>T | 942 | 76 | 21.32 | 3.879e-06 | 0.5673 |
| chr5:14915344 | rs835126 | - | A>G | 966 | 78 | 21.31 | 3.911e-06 | 0.5711 |
| chr2:102698360 | rs2041751 | IL1R1 | A>G | 6848 | 257 | 21.19 | 4.155e-06 | 1.411 |
| chr3:14937400 | rs1898040 | FGD5 | T>G | 5242 | 313 | 21.15 | 4.244e-06 | 0.7206 |
| chr10:59986805 | rs61749177 | IPMK | G>A | 221 | 26 | 20.89 | 4.863e-06 | 0.3956 |
| chr18:57785040 | rs75069525 | - | T>C | 284 | 31 | 20.76 | 5.204e-06 | 0.4272 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: L031 | Cellulitis of other parts of limb | 11/20 |