Statistics
| Case | Control |
|---|---|
| 695 | 459499 |
Phenotype Definition
Lymphocytoma cutis, or Spiegler-Fendt sarcoid, is classed as one of the pseudolymphomas, referring to inflammatory disorders in which the accumulation of lymphocytes on the skin resemble, clinically and histopathologically, cutaneous lymphomas. Careful clinical evaluation, histopathological and immunohistochemical exams may be needed to make the correct diagnosis. [PMID:24346899]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr23:151996723 | rs142811420 | CETN2 | T>C | 38 | 12186 | 24.95 | 5.877e-07 | 2.236 |
| chr7:86066506 | rs117929214 | - | A>G | 53 | 17765 | 24.69 | 6.726e-07 | 1.979 |
| chr8:69379087 | rs55654401 | C8orf34 | G>T | 610 | 458965 | 24.56 | 7.206e-07 | 0.7709 |
| chr23:100022675 | rs146267721 | - | T>C | 65 | 25455 | 23.33 | 1.362e-06 | 1.84 |
| chr8:55398033 | rs9792222 | - | C>T | 300 | 246411 | 21.4 | 3.737e-06 | 0.7424 |
| chr6:44223765 | rs114193300 | SLC35B2 | C>A | 49 | 16832 | 21.17 | 4.202e-06 | 1.93 |
| chr6:161758640 | rs1407212 | - | T>C | 138 | 62204 | 20.37 | 6.395e-06 | 1.493 |
| chr15:22980776 | rs62008564 | CYFIP1 | C>T | 47 | 16143 | 20.21 | 6.926e-06 | 1.926 |
| chr13:107561332 | rs9558896 | - | T>C | 330 | 264757 | 19.8 | 8.602e-06 | 0.7582 |
| chr2:216620599 | rs115607052 | - | G>A | 79 | 31564 | 19.64 | 9.329e-06 | 1.661 |
| chr23:100472473 | rs140013631 | - | G>A | 46 | 17136 | 19.57 | 9.676e-06 | 1.927 |
| chr4:78131621 | rs78875074 | CCNG2 | G>A | 51 | 18117 | 19.53 | 9.904e-06 | 1.86 |
| chr2:131904064 | rs76214160 | PLEKHB2 | A>G | 32 | 9847 | 19.03 | 1.284e-05 | 2.143 |
| chr9:7081110 | rs72703378 | KDM4C | G>A | 75 | 29905 | 18.98 | 1.32e-05 | 1.667 |
| chr5:36977003 | rs13163996 | NIPBL | A>G | 273 | 139819 | 18.82 | 1.433e-05 | 1.336 |
| chr9:20291602 | rs12344091 | - | A>G | 303 | 157098 | 18.59 | 1.618e-05 | 1.319 |
| chr2:62019643 | rs34495175 | - | C>T | 183 | 159783 | 18.54 | 1.66e-05 | 0.7129 |
| chr1:31223269 | rs116077605 | LAPTM5 | A>G | 88 | 36700 | 18.4 | 1.789e-05 | 1.596 |
| chr6:97414756 | rs11753834 | KLHL32 | A>G | 297 | 154069 | 18.37 | 1.818e-05 | 1.319 |
| chr5:99936178 | rs116695292 | - | A>G | 39 | 13000 | 18.19 | 1.994e-05 | 1.974 |
| chr7:86066506 | rs117929214 | - | A>G | 52 | 17203 | 26.36 | 2.828e-07 | 2.038 |
| chr8:69379087 | rs55654401 | C8orf34 | G>T | 569 | 436466 | 24.72 | 6.63e-07 | 0.7629 |
| chr23:100022675 | rs146267721 | - | T>C | 64 | 25153 | 24.1 | 9.122e-07 | 1.868 |
| chr6:44223765 | rs114193300 | SLC35B2 | C>A | 48 | 16217 | 22.88 | 1.728e-06 | 1.993 |
| chr8:69100070 | rs1155491 | PREX2 | A>G | 254 | 129723 | 21.0 | 4.6e-06 | 1.374 |
| chr23:151996723 | rs142811420 | CETN2 | T>C | 34 | 11414 | 20.59 | 5.685e-06 | 2.168 |
| chr15:22980776 | rs62008564 | CYFIP1 | C>T | 46 | 15924 | 20.21 | 6.922e-06 | 1.94 |
| chr19:39918351 | rs78287148 | PLEKHG2 | C>T | 38 | 12398 | 20.15 | 7.152e-06 | 2.062 |
| chr23:100472473 | rs140013631 | - | G>A | 45 | 16779 | 20.12 | 7.255e-06 | 1.959 |
| chr4:78131621 | rs78875074 | CCNG2 | G>A | 50 | 17782 | 20.03 | 7.616e-06 | 1.887 |
| chr9:20291602 | rs12344091 | - | A>G | 285 | 148131 | 19.42 | 1.047e-05 | 1.339 |
| chr5:36977003 | rs13163996 | NIPBL | A>G | 261 | 134703 | 19.11 | 1.232e-05 | 1.349 |
| chr9:7081110 | rs72703378 | KDM4C | G>A | 70 | 27793 | 19.1 | 1.24e-05 | 1.7 |
| chr7:138093986 | rs10225894 | - | G>A | 35 | 11260 | 18.95 | 1.34e-05 | 2.075 |
| chr14:43517217 | rs73332500 | - | A>G | 44 | 15405 | 18.7 | 1.527e-05 | 1.919 |
| chr18:2788541 | rs113835155 | SMCHD1 | G>A | 39 | 13189 | 18.47 | 1.724e-05 | 1.985 |
| chr17:27174335 | rs72848943 | FAM222B | G>A | 60 | 23065 | 18.46 | 1.738e-05 | 1.752 |
| chr15:51674017 | rs79753478 | GLDN | T>G | 53 | 19729 | 18.26 | 1.926e-05 | 1.805 |
| chr22:24610854 | rs117077425 | - | G>A | 47 | 16904 | 18.16 | 2.028e-05 | 1.865 |
| chr2:216620599 | rs115607052 | - | G>A | 76 | 31117 | 18.09 | 2.108e-05 | 1.644 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr7:86066506 | rs117929214 | - | A>G | 52 | 3127 | 24.95 | 5.87e-07 | 2.009 |
| chr8:69379087 | rs55654401 | C8orf34 | G>T | 569 | 78221 | 24.41 | 7.79e-07 | 0.7635 |
| chr6:44223765 | rs114193300 | SLC35B2 | C>A | 48 | 2894 | 22.9 | 1.711e-06 | 2.003 |
| chr23:100022675 | rs146267721 | - | T>C | 64 | 4682 | 22.75 | 1.844e-06 | 1.842 |
| chr23:151996723 | rs142811420 | CETN2 | T>C | 34 | 2074 | 20.92 | 4.799e-06 | 2.191 |
| chr8:69100070 | rs1155491 | PREX2 | A>G | 254 | 23249 | 20.91 | 4.808e-06 | 1.375 |
| chr4:78131621 | rs78875074 | CCNG2 | G>A | 50 | 3172 | 20.11 | 7.319e-06 | 1.896 |
| chr19:39918351 | rs78287148 | PLEKHG2 | C>T | 38 | 2221 | 19.92 | 8.076e-06 | 2.064 |
| chr23:100472473 | rs140013631 | - | G>A | 45 | 3082 | 19.87 | 8.275e-06 | 1.959 |
| chr7:138093986 | rs10225894 | - | G>A | 35 | 1976 | 19.85 | 8.376e-06 | 2.12 |
| chr4:149283684 | rs72729952 | NR3C2 | G>C | 67 | 4660 | 19.66 | 9.256e-06 | 1.737 |
| chr22:24610854 | rs117077425 | - | G>A | 47 | 2960 | 19.4 | 1.062e-05 | 1.91 |
| chr9:20291602 | rs12344091 | - | A>G | 285 | 26552 | 19.32 | 1.106e-05 | 1.34 |
| chr15:22980776 | rs62008564 | CYFIP1 | C>T | 46 | 2886 | 19.28 | 1.128e-05 | 1.919 |
| chr14:43517217 | rs73332500 | - | A>G | 44 | 2733 | 19.1 | 1.242e-05 | 1.94 |
| chr5:36977003 | rs13163996 | NIPBL | A>G | 261 | 24163 | 18.87 | 1.397e-05 | 1.348 |
| chr17:27174335 | rs72848943 | FAM222B | G>A | 60 | 4110 | 18.58 | 1.627e-05 | 1.761 |
| chr5:99936178 | rs116695292 | - | A>G | 38 | 2261 | 18.48 | 1.716e-05 | 2.012 |
| chr9:7081110 | rs72703378 | KDM4C | G>A | 70 | 5022 | 18.3 | 1.89e-05 | 1.686 |
| chr11:84448853 | rs75781049 | DLG2 | T>G | 178 | 15574 | 18.2 | 1.993e-05 | 1.409 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: A498 | Other bacterial infections of unspecified site | 1/20 |
| ICD: A499 | Bacterial infection, unspecified | 1/20 |
| ID | Name | Top Correlation |
|---|