Severe viral infection


Normal Case/Contol

GWAS of 0031691

Sibling Case/Control

No sibling GWAS available 0031691


Case Control
8641 451553

Phenotype Definition

An unusually severe viral infection. [PMID:21960712]

Phenotype Comment

The majority of viral infections acquired by nonimmunosuppressed individuals are asymptomatic or result in mild clinical manifestations. These individuals are able to mount effective immune responses that either clear the virus from the body or, for viruses that establish latency, maintain the virus in a dormant state. For individuals who are immunocompromised, because of a genetic immunodeficiency or immunosuppressive drug therapy, viral infections may result in life-threatening disease. Such patients present with infections that are severe, persistent, recurrent, or refractory to therapy and are usually caused by viruses of low virulence prevalent in the community.

Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: J189 Pneumonia, unspecified 4/20