Abnormal oral morphology

0031816

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
98302	361892

Phenotype Definition

Any structural anomaly of the mouth, which is also known as the oral cavity. []

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr6:396321	rs12203592	IRF4	C>T	44566	156639	91.44	1.153e-21	1.06
chr6:421281	rs62389423	-	G>A	36328	127708	72.2	1.943e-17	1.057
chr11:44843134	rs11038167	TSPAN18	A>C	1901	8548	63.2	1.866e-15	0.8169
chr13:74144529	rs9573252	-	C>G	4070	16974	51.95	5.696e-13	0.8807
chr1:169510139	rs13306334	F5	G>A	2164	9444	51.74	6.325e-13	0.8418
chr5:95194445	rs57525142	-	G>A	5162	21199	50.95	9.474e-13	0.8939
chr3:181586376	rs10937067	-	G>A	2553	10973	50.45	1.22e-12	0.8548
chr6:170602429	rs17860704	DLL1	T>C	2199	9519	47.59	5.261e-12	0.8488
chr16:30628333	rs12447859	ZNF689	G>A	2488	10611	47.32	6.044e-12	0.8572
chr2:26113913	rs78404020	-	A>G	2624	11193	46.85	7.65e-12	0.8613
chr6:93667780	rs9363020	-	G>A	2260	9731	45.76	1.336e-11	0.8533
chr2:108088349	rs2377892	-	G>A	2669	11325	44.34	2.756e-11	0.8658
chr1:54009583	rs41363049	GLIS1	C>T	2471	10528	43.48	4.273e-11	0.8623
chr9:87887178	rs2031823	-	T>G	3292	13735	42.31	7.788e-11	0.8806
chr15:47590746	rs72623947	SEMA6D	C>T	4944	20151	42.28	7.912e-11	0.9008
chr17:38489170	rs2715554	RARA	A>G	31190	110571	40.82	1.666e-10	1.045
chr17:38364764	rs55673000	-	C>T	32424	115059	40.42	2.045e-10	1.044
chr18:77563334	rs11665567	-	G>A	43905	156860	39.13	3.963e-10	1.039
chr1:212556551	rs3754142	PACC1	A>G	3494	14456	39.05	4.136e-10	0.888
chr19:49214470	rs281380	-	T>C	73788	277292	38.2	6.384e-10	0.9686
chr6:396321	rs12203592	IRF4	C>T	44000	154915	85.02	2.956e-20	1.058
chr6:421281	rs62389423	-	G>A	35798	126067	66.37	3.738e-16	1.055
chr17:38364764	rs55673000	-	C>T	30874	109590	37.89	7.466e-10	1.044
chr17:38489170	rs2715554	RARA	A>G	30412	107990	36.6	1.449e-09	1.044
chr7:114015707	rs12705960	FOXP2	A>C	96639	350493	32.76	1.044e-08	1.03
chr18:77563334	rs11665567	-	G>A	42027	150479	32.31	1.313e-08	1.036
chr6:475489	rs12210050	-	C>T	40628	145368	32.07	1.49e-08	1.036
chr13:58265596	rs9597588	PCDH17	A>G	45603	163757	28.3	1.041e-07	1.033
chr4:140867514	rs797090	MAML3	A>G	71770	268908	27.89	1.282e-07	0.9725
chr7:114223723	rs1229761	FOXP2	A>C	65060	244056	27.62	1.478e-07	0.972
chr13:59808492	rs7985532	-	G>A	50171	188924	27.49	1.576e-07	0.9699
chr16:30823047	rs4889490	-	G>T	75422	282413	27.47	1.598e-07	0.973
chr17:38544624	rs2715555	-	G>A	28634	102070	27.28	1.763e-07	1.039
chr7:89734282	rs39203	-	A>G	32012	114388	26.72	2.348e-07	1.036
chr7:114457983	rs73212672	-	G>A	15992	61497	26.42	2.752e-07	0.9535
chr16:30536918	rs10871453	ZNF768	C>G	79835	289459	26.41	2.768e-07	1.027
chr16:30566747	rs17850402	ZNF764	G>A	20056	71019	26.38	2.808e-07	1.044
chr6:31465030	rs6922431	MICB	T>C	9532	37167	26.32	2.889e-07	0.9414
chr1:201884952	rs2819348	LMOD1	T>C	70280	254228	25.95	3.51e-07	1.027
chr16:30174926	rs6565176	-	C>T	96466	350498	25.69	4.005e-07	1.026

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr25:154986418	rs142918084	-	C>G	6268	9528	28.68	8.518e-08	0.9151
chr25:155183483	rs73237015	-	G>A	35548	51014	26.14	3.172e-07	0.9617
chr17:47718188	rs10853111	SPOP	G>A	80808	114365	24.32	8.152e-07	0.9708
chr13:111792557	rs9559997	ARHGEF7	C>T	38130	51507	23.02	1.606e-06	1.037
chr7:114457983	rs73212672	-	G>A	15992	23292	22.27	2.367e-06	0.9506
chr16:89219366	rs72819315	ACSF3	G>T	12127	15972	21.57	3.408e-06	1.059
chr8:41667681	rs75663018	ANK1	G>T	2804	4341	21.4	3.737e-06	0.8932
chr5:150610965	rs153454	GM2A	G>A	36314	51929	20.41	6.264e-06	0.9663
chr7:70071086	rs73179429	AUTS2	T>G	6689	9979	20.36	6.417e-06	0.93
chr6:421281	rs62389423	-	G>A	35798	48378	20.25	6.781e-06	1.035
chr25:155058865	rs73234550	-	G>A	6619	8561	20.22	6.916e-06	1.078
chr6:396321	rs12203592	IRF4	C>T	44000	59641	20.07	7.46e-06	1.033
chr18:35143860	rs76655181	CELF4	A>G	15875	23074	20.04	7.568e-06	0.953
chr8:9154065	rs330081	-	A>C	86796	122517	19.58	9.653e-06	0.974
chr17:38489170	rs2715554	RARA	A>G	30412	41030	19.13	1.224e-05	1.037
chr1:1094979	rs7538773	-	A>G	75324	103054	19.07	1.262e-05	1.027
chr17:38364764	rs55673000	-	C>T	30874	41667	18.92	1.362e-05	1.036
chr17:163525	rs57332907	RPH3AL	G>T	19171	25627	18.86	1.409e-05	1.045
chr1:208314049	rs60447286	PLXNA2	C>A	23555	31606	18.81	1.447e-05	1.041
chr20:49073726	rs79764691	-	G>T	16267	23595	18.72	1.516e-05	0.955

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: F101	Harmful use	2/20
ICD: F103	Withdrawal state	2/20
ICD: J448	Other specified chronic obstructive pulmonary disease	2/20
ICD: L570	Actinic keratosis	2/20
ICD: L814	Other melanin hyperpigmentation	1/20
ICD: N86	Erosion and ectropion of cervix uteri	1/20
ICD: Y836	Removal of other organ (partial) (total)	1/20

ID	Name	Top Correlation
ICD-10: A020	Salmonella gastro-enteritis	0/20
ICD-10: B009	Herpesviral infection, unspecified	0/20
ICD-10: B24	Unspecified human immunodeficiency virus [HIV] disease	0/20
ICD-10: B349	Viral infection, unspecified	0/20
ICD-10: B370	Candidal stomatitis	0/20
ICD-10: B378	Candidiasis of other sites	0/20
ICD-10: B379	Candidiasis, unspecified	0/20
ICD-10: B99	Other and unspecified infectious diseases	0/20
ICD-10: C01	Malignant neoplasm of base of tongue	0/20
ICD-10: C021	Border of tongue	0/20
ICD-10: C029	Tongue, unspecified	0/20
ICD-10: C07	Malignant neoplasm of parotid gland	0/20
ICD-10: C099	Tonsil, unspecified	0/20
ICD-10: C320	Glottis	0/20
ICD-10: C440	Skin of lip	0/20
ICD-10: C772	Intra-abdominal lymph nodes	0/20
ICD-10: C80	Malignant neoplasm without specification of site	0/20
ICD-10: C838	Other types of diffuse non-Hodgkin's lymphoma	0/20
ICD-10: D101	Tongue	0/20
ICD-10: D110	Parotid gland	0/20
ICD-10: D130	Oesophagus	0/20
ICD-10: D170	Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0/20
ICD-10: D171	Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0/20
ICD-10: D172	Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0/20
ICD-10: D173	Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0/20
ICD-10: D175	Benign lipomatous neoplasm of intra-abdominal organs	0/20
ICD-10: D176	Benign lipomatous neoplasm of spermatic cord	0/20
ICD-10: D177	Benign lipomatous neoplasm of other sites	0/20
ICD-10: D179	Benign lipomatous neoplasm, unspecified	0/20
ICD-10: D230	Skin of lip	0/20
ICD-10: D370	Lip, oral cavity and pharynx	0/20
ICD-10: D510	Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0/20
ICD-10: D519	Vitamin B12 deficiency anaemia, unspecified	0/20
ICD-10: D62	Acute posthaemorrhagic anaemia	0/20
ICD-10: D759	Disease of blood and blood-forming organs, unspecified	0/20
ICD-10: E079	Disorder of thyroid, unspecified	0/20
ICD-10: E220	Acromegaly and pituitary gigantism	0/20
ICD-10: F112	Dependence syndrome	0/20
ICD-10: F121	Harmful use	0/20
ICD-10: F171	Harmful use	0/20
ICD-10: F172	Dependence syndrome	0/20
ICD-10: H021	Ectropion of eyelid	0/20
ICD-10: H023	Blepharochalasis	0/20
ICD-10: I479	Paroxysmal tachycardia, unspecified	0/20
ICD-10: I693	Sequelae of cerebral infarction	0/20
ICD-10: I859	Oesophageal varices without bleeding	0/20
ICD-10: J00	Acute nasopharyngitis [common cold]	0/20
ICD-10: J151	Pneumonia due to Pseudomonas	0/20
ICD-10: J343	Hypertrophy of nasal turbinates	0/20
ICD-10: J351	Hypertrophy of tonsils	0/20
ICD-10: J384	Oedema of larynx	0/20
ICD-10: J398	Other specified diseases of upper respiratory tract	0/20
ICD-10: J449	Chronic obstructive pulmonary disease, unspecified	0/20
ICD-10: K006	Disturbances in tooth eruption	0/20
ICD-10: K010	Embedded teeth	0/20
ICD-10: K011	Impacted teeth	0/20
ICD-10: K028	Other dental caries	0/20
ICD-10: K029	Dental caries, unspecified	0/20
ICD-10: K044	Acute apical periodontitis of pulpal origin	0/20
ICD-10: K045	Chronic apical periodontitis	0/20
ICD-10: K046	Periapical abscess with sinus	0/20
ICD-10: K047	Periapical abscess without sinus	0/20
ICD-10: K048	Radicular cyst	0/20
ICD-10: K049	Other and unspecified diseases of pulp and periapical tissues	0/20
ICD-10: K051	Chronic gingivitis	0/20
ICD-10: K053	Chronic periodontitis	0/20
ICD-10: K056	Periodontal disease, unspecified	0/20
ICD-10: K068	Other specified disorders of gingiva and edentulous alveolar ridge	0/20
ICD-10: K073	Anomalies of tooth position	0/20
ICD-10: K076	Temporomandibular joint disorders	0/20
ICD-10: K081	Loss of teeth due to accident, extraction or local periodontal disease	0/20
ICD-10: K083	Retained dental root	0/20
ICD-10: K089	Disorder of teeth and supporting structures, unspecified	0/20
ICD-10: K090	Developmental odontogenic cysts	0/20
ICD-10: K092	Other cysts of jaw	0/20
ICD-10: K108	Other specified diseases of jaws	0/20
ICD-10: K111	Hypertrophy of salivary gland	0/20
ICD-10: K112	Sialoadenitis	0/20
ICD-10: K115	Sialolithiasis	0/20
ICD-10: K116	Mucocele of salivary gland	0/20
ICD-10: K118	Other diseases of salivary glands	0/20
ICD-10: K119	Disease of salivary gland, unspecified	0/20
ICD-10: K120	Recurrent oral aphthae	0/20
ICD-10: K121	Other forms of stomatitis	0/20
ICD-10: K122	Cellulitis and abscess of mouth	0/20
ICD-10: K130	Diseases of lips	0/20
ICD-10: K132	Leukoplakia and other disturbances of oral epithelium, including tongue	0/20
ICD-10: K136	Irritative hyperplasia of oral mucosa	0/20
ICD-10: K137	Other and unspecified lesions of oral mucosa	0/20
ICD-10: K140	Glossitis	0/20
ICD-10: K148	Other diseases of tongue	0/20
ICD-10: K149	Disease of tongue, unspecified	0/20
ICD-10: K635	Polyp of colon	0/20
ICD-10: K768	Other specified diseases of liver	0/20
ICD-10: K929	Disease of digestive system, unspecified	0/20
ICD-10: L059	Pilonidal cyst without abscess	0/20
ICD-10: L270	Generalised skin eruption due to drugs and medicaments	0/20
ICD-10: L439	Lichen planus, unspecified	0/20
ICD-10: L578	Other skin changes due to chronic exposure to nonionising radiation	0/20
ICD-10: L819	Disorder of pigmentation, unspecified	0/20
ICD-10: L83	Acanthosis nigricans	0/20
ICD-10: M254	Effusion of joint	0/20
ICD-10: M350	Sicca syndrome [Sjogren]	0/20
ICD-10: M359	Systemic involvement of connective tissue, unspecified	0/20
ICD-10: M798	Other specified soft tissue disorders	0/20
ICD-10: M858	Other specified disorders of bone density and structure	0/20
ICD-10: M898	Other specified disorders of bone	0/20
ICD-10: N085	Glomerular disorders in systemic connective tissue disorders	0/20
ICD-10: N904	Leukoplakia of vulva	0/20
ICD-10: O996	Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0/20
ICD-10: R065	Mouth breathing	0/20
ICD-10: R066	Hiccough	0/20
ICD-10: R21	Rash and other nonspecific skin eruption	0/20
ICD-10: R238	Other and unspecified skin changes	0/20
ICD-10: R253	Fasciculation	0/20
ICD-10: R490	Dysphonia	0/20
ICD-10: T390	Salicylates	0/20
ICD-10: T819	Unspecified complication of procedure	0/20
ICD-10: T884	Failed or difficult intubation	0/20
ICD-10: T885	Other complications of anaesthesia	0/20
ICD-10: Y834	Other reconstructive surgery	0/20
ICD-10: Y839	Surgical procedure, unspecified	0/20

Abnormal oral morphology

0031816

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ