Statistics
| Case | Control |
|---|---|
| 46160 | 414034 |
Phenotype Definition
Abnormal appearance of material expectorated (coughed up) from the respiratory system and that is composed of mucus but may contain other substances such as pus, blood, microorganisms, and fibrin. []
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32612430 | Affx-37072023 | HLA-DQA1 | C>T | 38525 | 366295 | 242.3 | 1.223e-54 | 0.8983 |
| chr6:32620775 | rs17843619 | - | A>C | 36553 | 347745 | 227.6 | 1.944e-51 | 0.9004 |
| chr6:32613712 | rs9273215 | HLA-DQA1 | A>G | 36661 | 348824 | 226.8 | 3.012e-51 | 0.9007 |
| chr6:32620399 | rs17843606 | - | T>G | 35710 | 340169 | 226.0 | 4.489e-51 | 0.8999 |
| chr6:32615458 | rs17612576 | - | A>G | 36496 | 346995 | 224.4 | 9.781e-51 | 0.901 |
| chr6:32627714 | rs1063355 | HLA-DQB1 | G>T | 36687 | 348804 | 224.2 | 1.104e-50 | 0.9013 |
| chr6:32634838 | rs9274552 | HLA-DQB1 | C>A | 36121 | 343219 | 222.7 | 2.334e-50 | 0.901 |
| chr6:32612488 | rs9273088 | HLA-DQA1 | C>A | 36551 | 347587 | 222.2 | 3.043e-50 | 0.9015 |
| chr6:32623430 | rs9273339 | - | A>G | 36720 | 349116 | 220.4 | 7.246e-50 | 0.902 |
| chr6:32625869 | Affx-28496566 | - | C>T | 35121 | 332841 | 215.5 | 8.732e-49 | 0.9012 |
| chr6:32635809 | rs3828790 | HLA-DQB1 | C>T | 35875 | 340340 | 212.7 | 3.554e-48 | 0.903 |
| chr6:32636866 | rs3134996 | - | T>A | 32696 | 311409 | 193.3 | 6.13e-44 | 0.9056 |
| chr6:32602430 | rs17211510 | HLA-DQA1 | C>A | 21256 | 206768 | 188.5 | 6.845e-43 | 0.8942 |
| chr6:32600057 | rs35242582 | HLA-DQA1 | A>G | 21741 | 210723 | 177.6 | 1.62e-40 | 0.8979 |
| chr6:32607376 | rs34250758 | HLA-DQA1 | G>A | 20695 | 169568 | 173.1 | 1.527e-39 | 1.115 |
| chr6:32582650 | rs3104413 | - | C>G | 19540 | 159529 | 172.8 | 1.778e-39 | 1.118 |
| chr2:102960824 | rs2160203 | IL1RL1 | A>G | 21534 | 208460 | 170.4 | 6.101e-39 | 0.8996 |
| chr6:32577973 | rs532965 | - | T>G | 19687 | 160850 | 168.9 | 1.295e-38 | 1.116 |
| chr2:102954213 | rs72823646 | IL1RL1 | G>A | 12417 | 123923 | 164.8 | 1.025e-37 | 0.8787 |
| chr6:32583357 | rs6931277 | - | A>T | 19280 | 157412 | 164.6 | 1.135e-37 | 1.116 |
| chr6:32612430 | Affx-37072023 | HLA-DQA1 | C>T | 35447 | 340521 | 256.1 | 1.189e-57 | 0.8921 |
| chr6:32620775 | rs17843619 | - | A>C | 33741 | 324411 | 244.0 | 5.205e-55 | 0.8936 |
| chr6:32613712 | rs9273215 | HLA-DQA1 | A>G | 33843 | 325425 | 243.1 | 8.137e-55 | 0.8939 |
| chr6:32620399 | rs17843606 | - | T>G | 32961 | 317379 | 242.5 | 1.105e-54 | 0.893 |
| chr6:32615458 | rs17612576 | - | A>G | 33692 | 323762 | 241.0 | 2.418e-54 | 0.8942 |
| chr6:32627714 | rs1063355 | HLA-DQB1 | G>T | 33867 | 325406 | 240.4 | 3.14e-54 | 0.8945 |
| chr6:32634838 | rs9274552 | HLA-DQB1 | C>A | 33346 | 320201 | 239.6 | 4.797e-54 | 0.894 |
| chr6:32612488 | rs9273088 | HLA-DQA1 | C>A | 33734 | 324254 | 239.3 | 5.494e-54 | 0.8945 |
| chr6:32623430 | rs9273339 | - | A>G | 33891 | 325644 | 237.1 | 1.66e-53 | 0.8952 |
| chr6:32625869 | Affx-28496566 | - | C>T | 32431 | 310485 | 231.0 | 3.549e-52 | 0.8946 |
| chr6:32635809 | rs3828790 | HLA-DQB1 | C>T | 33109 | 317525 | 230.0 | 5.825e-52 | 0.8959 |
| chr6:32602430 | rs17211510 | HLA-DQA1 | C>A | 19699 | 193868 | 201.2 | 1.159e-45 | 0.8872 |
| chr6:32636866 | rs3134996 | - | T>A | 30829 | 296007 | 197.8 | 6.17e-45 | 0.9017 |
| chr6:32607376 | rs34250758 | HLA-DQA1 | G>A | 19961 | 163329 | 195.3 | 2.245e-44 | 1.126 |
| chr6:32582650 | rs3104413 | - | C>G | 18909 | 154285 | 191.8 | 1.318e-43 | 1.127 |
| chr6:32600057 | rs35242582 | HLA-DQA1 | A>G | 20171 | 197790 | 190.2 | 2.91e-43 | 0.891 |
| chr6:32577973 | rs532965 | - | T>G | 19057 | 155610 | 187.1 | 1.342e-42 | 1.125 |
| chr6:32583357 | rs6931277 | - | A>T | 18663 | 152293 | 181.5 | 2.316e-41 | 1.124 |
| chr6:32428062 | rs9268833 | - | C>T | 31105 | 261010 | 179.2 | 7.231e-41 | 1.103 |
| chr6:32428115 | rs9268835 | - | G>A | 31076 | 260958 | 178.2 | 1.214e-40 | 1.103 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32612430 | Affx-37072023 | HLA-DQA1 | C>T | 35447 | 78791 | 181.6 | 2.13e-41 | 0.8952 |
| chr6:32620775 | rs17843619 | - | A>C | 33741 | 75026 | 170.3 | 6.266e-39 | 0.8974 |
| chr6:32613712 | rs9273215 | HLA-DQA1 | A>G | 33843 | 75276 | 170.1 | 6.998e-39 | 0.8977 |
| chr6:32620399 | rs17843606 | - | T>G | 32961 | 73421 | 170.0 | 7.463e-39 | 0.8967 |
| chr6:32627714 | rs1063355 | HLA-DQB1 | G>T | 33867 | 75249 | 167.4 | 2.726e-38 | 0.8985 |
| chr6:32612488 | rs9273088 | HLA-DQA1 | C>A | 33734 | 74980 | 167.3 | 2.843e-38 | 0.8983 |
| chr6:32615458 | rs17612576 | - | A>G | 33692 | 74882 | 167.2 | 2.982e-38 | 0.8983 |
| chr6:32623430 | rs9273339 | - | A>G | 33891 | 75318 | 165.2 | 8.099e-38 | 0.899 |
| chr6:32634838 | rs9274552 | HLA-DQB1 | C>A | 33346 | 73945 | 162.6 | 3.078e-37 | 0.8992 |
| chr6:32635809 | rs3828790 | HLA-DQB1 | C>T | 33109 | 73423 | 158.5 | 2.405e-36 | 0.9003 |
| chr6:32625869 | Affx-28496566 | - | C>T | 32431 | 71799 | 158.2 | 2.866e-36 | 0.8993 |
| chr6:32636866 | rs3134996 | - | T>A | 30829 | 68584 | 146.3 | 1.101e-33 | 0.9027 |
| chr6:32602430 | rs17211510 | HLA-DQA1 | C>A | 19699 | 44691 | 134.2 | 4.937e-31 | 0.8939 |
| chr2:102954213 | rs72823646 | IL1RL1 | G>A | 11580 | 27037 | 125.4 | 4.193e-29 | 0.8752 |
| chr6:32600057 | rs35242582 | HLA-DQA1 | A>G | 20171 | 45588 | 125.3 | 4.282e-29 | 0.8981 |
| chr2:102953617 | rs3771180 | IL1RL1 | G>T | 11617 | 27078 | 122.4 | 1.908e-28 | 0.8768 |
| chr2:102960824 | rs2160203 | IL1RL1 | A>G | 20145 | 45471 | 121.8 | 2.586e-28 | 0.8994 |
| chr2:102931534 | rs72823632 | IL1RL1 | C>T | 11710 | 27268 | 120.6 | 4.715e-28 | 0.878 |
| chr2:102955082 | rs13408661 | IL1RL1 | G>A | 10460 | 24464 | 114.2 | 1.172e-26 | 0.8752 |
| chr6:32635092 | rs9274569 | HLA-DQB1 | C>A | 40849 | 81006 | 111.4 | 4.885e-26 | 1.089 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: J459 | Asthma, unspecified | 18/20 |